Medicine and Health Sciences Commons^™

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Neuropsychological Sequelae Of Brain Tumors, John L. Fisk, Jerel E. Del Dotto

Henry Ford Hospital Medical Journal

Investigation of the neuropsychological sequelae of brain tumors is extremely complex largely because the neurobehavioral consequences of brain tumors depend upon complex interactions among disease and treatment variables as well as patient characteristics. To illustrate some of these complexities, we present case studies of two patients in whom the behavioral outcome was not easily predictable on the basis of our current understanding of brain-behavior relationships in tumor patients. The case studies do illustrate how neuropsychological evaluation aids in identifying cognitive deficits which have implications for subsequent quality of life. Recommendations for future experiments and statistical analyses of neurobehavioral data of …

Health And Adjustment In Young Adults: Preliminary Findings From An Epidemiologic Survey, Naomi Breslau, Glenn C. Davis, Patricia Andreski

Henry Ford Hospital Medical Journal

No abstract provided.

Response To Cpap And Uppp In Apnea, Frank J. Zorick, Timothy Roehrs, William Conway, George Potts, Thomas Roth

Henry Ford Hospital Medical Journal

Ninety-two consecutive patients with obstructive sleep apnea syndrome (OSAS) were studied before and six weeks after treatment with either nasal continuous positive airway pressure (CPAP) or uvulopalatopharyngoplasty (UPPP) (n = 46 per group). Assignment of patients to treatment was based on clinical considerations and patient preference. Patients were assessed by nocturnal polysomnography and performance on the Multiple Sleep Latency Test (MSLT) the following day. Before treatment, the CPAP and UPPP groups did not differ in sleep-related respiratory disturbance, oxygenation during sleep, fragmentation of sleep, or the level of excessive daytime sleepiness indicated by the MSLT. Both treatments produced significant improvement …

Perioperative Management Of Diabetes, Gary W. Edelson, J. David Fachnie, Fred W. Whitehouse

Henry Ford Hospital Medical Journal

No abstract provided.

The Physiologic Basis For Nutritional Support In Hepatic Failure, John J. Fath

Henry Ford Hospital Medical Journal

Hepatic failure is often perceived as a unidimensional progression from near normal clinical function (Child's class A) to overt clinical failure (Child's class C). As this view fails to distinguish between patients who are capable of using exogenous protein and those who cannot, it hinders the nutritional support team in determining protein supplementation. This report addresses the physiologic basis for variable findings in hepatic failure and proposes a simple definition of hepatic faliure based upon ability to utilize amino acids.

Nutritional Implications Of Liver Transplantation, Jeanette M. Hasse

Henry Ford Hospital Medical Journal

Malnutrition is a common problem of patients undergoing liver transplantation. To treat malnutrition, it must first be identified through a nutritional assessment. Because many objective nutritional assessment parameters have limitations in end-stage liver disease, subjective nutritional indicators may be used as an alternative. Nutritional needs following transplantation are categorized as short and long term. The short-term nutritional goal, anabolism, can be complicated by the nutritional status of the patient, surgical procedures, and necessary medications. The increased nutrient needs during the early posttransplant phase require particular nutritional support. Nutrition-related problems following transplantation may include obesity, hyperlipidemia. hypertension, diabetes mellitus. hyperkalemia, edema, …

Allogeneic Whole Pancreas Transplantation In Insulin-Dependent Diabetes Mellitus, José Goldman, Heung K. Oh, Mark G. Webb, Martin Mozes, Nancy Turza, Warren L. Kupin, K. K. Venkat, Ramón Del Busto

Henry Ford Hospital Medical Journal

A clinical whole organ pancreas transplantation program for patients with insulin-dependent diabetes mellitus complicated by end-stage renal disease was initiated at Henry Ford Hospital in 1987. Five patients have received pancreatic allografts after a previous kidney transplant (phase 1), and six patients had simultaneous pancreas-kidney transplants (phase 2). Ten patients had functioning pancreatic grafts after surgery, and all of them had normal carbohydrate tolerance with appropriate plasma free insulin responses to an oral glucose tolerance test three months after transplantation. As long as 28 months postsurgery six patients remained free of insulin requirements; however, one patient rejected the pancreatic allograft, …

Passive Inhalation Of Cocaine By Infants, Sabrina M. Heidemann, Mark G. Goetting

Henry Ford Hospital Medical Journal

Cocaine abuse has increased greatly in recent years, creating important medical, legal, and social problems. Urine drug testing is used to diagnose cocaine ingestion. The presence of the cocaine metabolite benzoylecgonine (BZ) is commonly believed to be proof of recent cocaine intoxication. However, oral ingestion of even a minute quantity of cocaine can result in a positive test result. BZ was detected in the urine of four nonbreast-fed infants aged 6 weeks to 14 months who were admitted with diagnoses unrelated to cocaine poisoning. These infants were exposed to cocaine by passive inhalation of vapors generated by adult caretakers smoking …

Temperature And Pain Changes Resulting From Post Surgical (Arthroscopy) Application Of Cold Packs, Caroline L. Creager

All-Inclusive List of Electronic Theses and Dissertations

Post-surgical cold applications are beneficial to orthopedic surgery patients. However, their use is limited because of the difficulty in maintaining a constant temperature, increased need for attention, and unwanted leaks or condensation from ice bags. Twenty-one arthroscopic surgery patients were divided into three groups: a Dura*Kold cold pack group, an Aircast Cryo/cuff compression dressing group, and a control group. Six dependent variables were examined: subjective pain ratings three and 48 hours after surgery, a subjective rating of functional activity 48 hours after surgery, skin temperature for three hours after surgery, and pain medication consumed during three hours and 48 hours …

Psychiatry Update: Current Research And Other New Developments, Glenn C. Davis, Naomi Breslau

Henry Ford Hospital Medical Journal

No abstract provided.

Effects Of Age, Neuropsychological Impairment, And Medication On Regional Cerebral Blood Flow In Schizophrenia And Major Affective Disorder, Perry C. Goldstein, Gregory G. Brown, Andrew Marcus, James R. Ewing

Henry Ford Hospital Medical Journal

Reports of abnormalities of regional cerebral blood flow (rCBF) in patients with schizophrenia and major affective disorder are contradictory. To gain a better understanding of the possible sources of these contradictions, the rCBF and neuropsychological functioning of 15 schizophrenics, 15 patients with major affective disorder, and 15 age-matched controls were studied. No group differences in overall rCBF, percent frontal devialion in flow, or rCBF asymmetries were observed. Both overall rCBF and percent frontal deviation of rCBF were reduced with greater age and with increasing neuropsychological impairment. Dosage of neuroleptic medication was associated with reduced whole brain flow, not with percent …

The Ketterer Stress Symptom Frequency Checklist: Anger And The Severity Of Coronary Artery Disease, Mark W. Ketterer

Henry Ford Hospital Medical Journal

Recent research suggests that the most potent feature of the Type A behavior pattern for prospectively predicting cardiac disease is aggravation, irritation, anger, and impatience (AIAI). The present study examines psychometric properties of a new AIAI measure and its relationship to the severity of coronary artery disease (CAD). Subjects included 61 males undergoing coronary angiography. Comparisons were made of mean psychometric scores across groupings, defined by number of vessels occluded. These comparisons showed that the normal or subclinically occluded coronary angiographic group had high levels of depression and anxiety. Higher levels of AIAI were observed in patients with multivessel CAD …

Psychometric Profiles Of Patient Populations With Excessive Daytime Sleepiness, Edward J. Stepanski, Jon J. Markey, Frank J. Zorick, Thomas Roth

Henry Ford Hospital Medical Journal

Patients with narcolepsy have more psychiatric symptoms than normal controls as measured by psychometric tests. However, it is unclear whether these findings are specific to narcolepsy, as some studies have suggested, or related to excessive daytime sleepiness (EDS) or to chronic illness. We compared a group of 56 narcoleptics to age- and sex-matched controls with EDS. A group of 48 individuals with normal sleep architecture was also used as an additional control group. Both the narcoleptic group and the EDS-control group had significantly greater scores on Minnesota Multiphasic Personality Inventory scales hut were not different from each other. Our data …

From His Rib, J. David Fachnie

Henry Ford Hospital Medical Journal

No abstract provided.

An Overview Of Renal Transplantation At Henry Ford Hospital, Warren L. Kupin, K. K. Venkat, Martin Mozes, Hajime Hayashi, Heung K. Oh

Henry Ford Hospital Medical Journal

No abstract provided.

Rectal Non-Hodgkin's Lymphoma: A Clinicopathologic Study And Review, Cary A. Gottlieb, Eyal Meiri, Koichi Maeda

Henry Ford Hospital Medical Journal

A total of 11 patients with lymphomatous involvement of the rectum were seen at Henry Ford Hospital between 1964 and 1987. Eight of these patients had primary rectal lymphoma and three had secondary rectal lymphoma. These patients' clinical presentation and course as well as pathological findings are described and compared with cases previously reported. As identified in ours and others' series, rectal lymphomas are associated with the acquired immunodeficiency syndrome and tend to have a B-cell phenotype.

Lipohyperplasia Of Ileocecal Valve, Causing Recurrent Intussusception, Lacey Walke, Adrian J. Christie

Henry Ford Hospital Medical Journal

Lipohyperplasia of the ileocecal valve is a fairly common entity that occasionally behaves as an intestinal tumor, causing obstruction, sometimes with intussusception, or bleeding, which may be acute or chronic. Most often occurring in middle-aged or elderly women, it may be mistaken clinically and radiologically for carcinoma or other neoplasms. Its differentiation is best made by endoscopy, confirmed if possible by biopsy. Differentiation is important, as the treatment is a limited ileal and cecal resection, instead of a blind hemicolectomy. A recent study suggests possible associations with other medical conditions. We describe the clinical and pathological findings of this entity …

The Smoke-Out At Henry Ford Hospital, Or How Henry Ford Created A Smoke-Free Environment, Sidney Goldstein

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Concentration Of Leukotrienes B4 And C4 In Human Periradicular Lesions, Elisabetta Cotti

Loma Linda University Electronic Theses, Dissertations & Projects

The 5-lipoxygenase metabolites of arachidonic acid such as leukotrienes (LT) B₄ and C₄, are potent mediators of inflammation. The purpose of this investigation was to determine the concentrations of LTB₄ and LTC₄ in human periradicular lesions. Specimens from asymptomatic and symptomatic patients were obtained and immediately frozen in liquid nitrogen. Periradicular tissues from unerupted third molars as well as chronically inflamed gingival tissues were also obtained, frozen and were used as negative and positive controls respectively. The concentrations of LTB₄ and LTC₄ were determined by the reverse phase high pressure liquid chromatography. Representative …

1990scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti

Ua66 1989-1990 Annual Report, Wku Ogden College Of Science & Engineering

WKU Administration Documents

Annual report created by then Ogden College of Science, Technology and Health which highlights students, faculty, alumni, international activities, facilities and equipment and departments:

• Agriculture
• Allied Health
• Biology
• Chemistry
• Computer Science
• Engineering Technology
• Geography & Geology
• Health & Safety
• Industrial Technology
• Mathematics
• Nursing
• Physics & Astronomy

Santa Clara Magazine, Volume 33 Number 1, Fall 1990, Santa Clara University

Santa Clara Magazine

12 - PRIESTS & MARRIAGE The Pope has allowed the ordination of nearly 50 married Episcopal priests since 1980. Some see this as a sign of hope for a married priesthood . By Julie Sly '82

18 - THE POWER OF ONE Because of her own personal tragedy, Mary Beth Cahill Phillips '76 forced the state of California to form Trustline, a registry parents can use to check out a nanny. By Susan Frey

20 - THE ART OF BIOGRAPHY Our natural curiosity about each other tempts us into reading biographies the same way we turn to novels. Is peering …

1991 Beef Cattle Report, Darrell W. Nelson

Nebraska Beef Cattle Reports

A two-year study tested the hypothesis that growth rate interacts with bull exposure to influence age at puberty in heifers. Heifers exposed to sterile bulls and fed to achieve a high growth rate (1.8 lb/day) attained puberty 73 days earlier than heifers not exposed to bulls and fed to a moderate growth rate (1.3 lb/day). Heifers exposed to bulls and fed to achieve a moderate growth rate attained puberty at ages similar to heifers not exposed to bulls and fed to a high growth rate. Furthermore. heifers receiving these two treatments attained puberty 23 days earlier than heifers not exposed …

Assessment Of Lipid Extraction From Human Bone On Subsequent Demineralization, Jaeeun Lee

Biological Sciences Theses & Dissertations

The purpose of this study was to assess the effectiveness of various solvents m removal of lipids from human bone, and to determine the effects of lipid extraction on subsequent acid solubilization of the mineral components of bone. Specifically, the following processing steps were studied; 1) ground human bone was de fatted in various ethanol / water mixtures, and / or chloroform / methanol ( 2: 1, v:v ), 2) ground human bone which had lipids extracted ( in absolute ethanol ) and bone which had not had lipids extracted were demineralized using vanous concentrations of hydrochloric acid to assess …

Activation In Vitro Of Transfer Rna-Guanine Ribosyltransferase By Protein Kinase C, Panayota Eriotou

Chemistry & Biochemistry Theses & Dissertations

The purpose of this study was to isolate and purify the enzymes, transfer RNA-guanine ribosyltrasferase and protein kinase C, and to determine whether the phosphorylating enzyme activates the insertion enzyme in vitro. Transfer RNA-guanine ribosyltransferase lost activity within several days after isolation and total, complete reactivation was accomplished in the presence of protein kinase C. This demonstrated that ribosyltransferase's instability is related to the degree of its phosphorylation. It is proposed that modification of tRNA is controlled by protein kinase C. Deactivation of the insertion enzyme leads to hypomodified tRNA which in turn is associated with neoplasia. Potential use …

Application Of Dna Fingerprints For Cell-Line Individualization, Dennis A. Gilbert, Yvonne Reid, Mitchell H. Gail, David Pee, Christine White, Robert J. Hay, Stephen J. O'Brien

Biology Faculty Articles

DNA fingerprints of 46 human cell lines were derived using minisatellite probes for hypervariable genetic loci. The incidence of 121 HaeIII DNA fragments among 33 cell lines derived from unrelated individuals was used to estimate allelic and genotypic frequencies for each fragment and for composite individual DNA fingerprints. We present a quantitative estimate of the extent of genetic difference between individuals, an estimate based on the percentage of restriction fragments at which they differ. The average percent difference (APD) among pairwise combinations from the population of 33 unrelated cell lines was 76.9%, compared with the APD in band sharing …

Federal Technology Transfer: Should We Build Subarus In Bethesda, Christopher J. Harnett

RISK: Health, Safety & Environment (1990-2002)

A critical examination of a policy designed to encourage commercial exploitation of federally funded biomedical research. The author argues that the implementation of this policy threatens the integrity of basic science in America.

Laminin Potentiates Differentiation Of Pcc4uva Embryonal Carcinoma Into Neurons, T. M. Sweeney, Roy C. Ogle, C. D. Little

School of Medical Diagnostics & Translational Sciences Publications

The embryonal carcinoma PCC4uva differentiates into neurons in response to treatment with retinoic acid and dbcAMP. We used this in vitro model system to study the effects of laminin on early neural differentiation. Laminin substrata markedly potentiate neural differentiation of retinoic acid and dbcAMP-treated cultures. Only laminin induced more rapid neural cell body clustering, neurite growth and neurite fasciculation as compared to type IV collagen, type I collagen, and fibronectin substrata. Exogenous laminin substrata promoted greater cell attachment, cellular spreading and growth to confluence than type IV collagen, type I collagen, fibronectin and glass substrata. Laminin-induced effects were inhibited by …