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Articles 1 - 30 of 51

Full-Text Articles in Systems Biology

The Dynamics Of Synchrony On Replicating Biological Populations, Montse Torres Garcia, Kevin Mcgoff, Francis Motta, Breschine Cummins, Steve Haase May 2026

The Dynamics Of Synchrony On Replicating Biological Populations, Montse Torres Garcia, Kevin Mcgoff, Francis Motta, Breschine Cummins, Steve Haase

Biology and Medicine Through Mathematics Conference

No abstract provided.


Data-Driven Modeling Of Dynamics And Adaptation In Mapk Pathway, Elisha Erzoah, Maria Emelianenko, Mariaelena Pierobon Nov 2025

Data-Driven Modeling Of Dynamics And Adaptation In Mapk Pathway, Elisha Erzoah, Maria Emelianenko, Mariaelena Pierobon

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Reconstructing Gene Regulatory Networks From Time-Series Data In Knime, Raina Robeva Nov 2025

Reconstructing Gene Regulatory Networks From Time-Series Data In Knime, Raina Robeva

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


[Kadel] Robust Basins, Fragile Attractors: A New View On Boolean Network Dynamics, Claus Kadelka Nov 2025

[Kadel] Robust Basins, Fragile Attractors: A New View On Boolean Network Dynamics, Claus Kadelka

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


[Kadel] Understanding Aging In Worms Using Boolean Modeling, Brandilyn Stigler Nov 2025

[Kadel] Understanding Aging In Worms Using Boolean Modeling, Brandilyn Stigler

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


[Kadel] A Multilevel Extension Of Boolean Networks Captures Topologically-Stable Hybrid Attractors, Kishore Hari Nov 2025

[Kadel] A Multilevel Extension Of Boolean Networks Captures Topologically-Stable Hybrid Attractors, Kishore Hari

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Trpv1 And Its Co‑Expressed Genes Are Associated With The Progression Of Hepatocellular Carcinoma, Bhuvnesh P. Sharma, Himanshu N. Singh, Sanjay Kumar, Deepak Verma, Deepak Parashar, Murali M. Yallapu, Everardo Cobos, Subhash C. Chauhan, Vivek K. Kashyap Mar 2025

Trpv1 And Its Co‑Expressed Genes Are Associated With The Progression Of Hepatocellular Carcinoma, Bhuvnesh P. Sharma, Himanshu N. Singh, Sanjay Kumar, Deepak Verma, Deepak Parashar, Murali M. Yallapu, Everardo Cobos, Subhash C. Chauhan, Vivek K. Kashyap

Research Symposium

Background: Hepatocellular carcinoma (HCC) is the most common type of liver cancer. Transient receptor potential vanilloid 1 (TRPV1) is a nonselective Ca2+ channel protein widely expressed and plays a significant role in cancer initiation and progression. However, the biological significance of TRPV1 in HCC has not been systematically and comprehensively investigated. This study used deep data mining and transcriptomics analyses to describe the significance of TRPV1 expression and its association with HCC prognosis.

Methods: Download the RNA expression of TRPV1 from the Cancer Genome Atlas (TCGA), Genotype Tissue Expression Atlas (GTEx), Tumor Immune Estimation Resource (TIMER), and the UALCAN …


The Correlation Between Temporomandibular Disorder (Tmd) And Vitamin D Deficiency, Iris Kim, Claudia Freitas Feb 2025

The Correlation Between Temporomandibular Disorder (Tmd) And Vitamin D Deficiency, Iris Kim, Claudia Freitas

Annual Research Symposium

No abstract provided.


Leveraging Quantitative Systems Pharmacology For Dose Optimization In Oncology Drug Development, Blerta Shtylla Nov 2024

Leveraging Quantitative Systems Pharmacology For Dose Optimization In Oncology Drug Development, Blerta Shtylla

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Kreig: Quantifying The Relationship Between Sars-Cov-2 Viral Load And Infectiousness, Aurelien Marc Nov 2024

Kreig: Quantifying The Relationship Between Sars-Cov-2 Viral Load And Infectiousness, Aurelien Marc

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Study Of Different Treatment Strategies In Epidemic Models Using Nonlinear Model Predictive Control, Hector Puebla, Luis A. Ricardez-Sandoval, Priti Kumar Roy Nov 2024

Study Of Different Treatment Strategies In Epidemic Models Using Nonlinear Model Predictive Control, Hector Puebla, Luis A. Ricardez-Sandoval, Priti Kumar Roy

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modelling Saccharomyces Cerevisiae For The Production Of Fermented Beverages, Paul A. Valle Dr., Yolocuauhtli Salazar Dr., Luis N. Coria Dr., Oscar N. Soto Dr., Jesus B. Paez Dr. Nov 2024

Modelling Saccharomyces Cerevisiae For The Production Of Fermented Beverages, Paul A. Valle Dr., Yolocuauhtli Salazar Dr., Luis N. Coria Dr., Oscar N. Soto Dr., Jesus B. Paez Dr.

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Msis-Kadelka: Modularizing The Control Search For Biological Systems, David Murrugarra Nov 2023

Msis-Kadelka: Modularizing The Control Search For Biological Systems, David Murrugarra

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Msis-Kadelka: Algebraic Methods For Inferring Discrete Models Of Biological Networks, Brandilyn Stigler Nov 2023

Msis-Kadelka: Algebraic Methods For Inferring Discrete Models Of Biological Networks, Brandilyn Stigler

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Msis-Kadelka: Canalization Reduces The Nonlinearity Of Regulation In Biological Networks, Claus Kadelka, David Murrugarra Nov 2023

Msis-Kadelka: Canalization Reduces The Nonlinearity Of Regulation In Biological Networks, Claus Kadelka, David Murrugarra

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Systems Network Analysis Of Protein Interaction Network (Pin) For Deducing Molecular Mechanistic Action Of Bap Induced Carcinogenesis, Anukriti ., Anupam Dhasmana, Uma Bhardwaj Sep 2023

Systems Network Analysis Of Protein Interaction Network (Pin) For Deducing Molecular Mechanistic Action Of Bap Induced Carcinogenesis, Anukriti ., Anupam Dhasmana, Uma Bhardwaj

Research Symposium

Background: Benzo[a]pyrene (BaP), a polycyclic aromatic hydrocarbon, has been placed in group 1 by IARC which indicates that it is a potential carcinogen to human beings. It has shown tumorigenic properties in approximately all animal model systems. In the current study, we have tried to identify the most probable biomolecular targets of BaP using systems biology approach.

Method: All the proteins that interact with BaP were extracted from T3DB. STRING-db was used to generate the Protein- protein interaction network (PPIN). Various apps of cytoscape software were used for network analysis, modulation and GO enrichment analysis. By developing biokinetic …


Modeling Nonsegmented Negative-Strand Rna Virus (Nnsv) Transcription With Ejective Polymerase Collisions And Biased Diffusion, Felipe-Andres Piedra Sep 2023

Modeling Nonsegmented Negative-Strand Rna Virus (Nnsv) Transcription With Ejective Polymerase Collisions And Biased Diffusion, Felipe-Andres Piedra

Research Symposium

Background: The textbook model of NNSV transcription predicts a gene expression gradient. However, multiple studies show non-gradient gene expression patterns or data inconsistent with a simple gradient. Regarding the latter, several studies show a dramatic decrease in gene expression over the last two genes of the respiratory syncytial virus (RSV) genome (a highly studied NNSV). The textbook model cannot explain these phenomena.

Methods: Computational models of RSV and vesicular stomatitis virus (VSV – another highly studied NNSV) transcription were written in the Python programming language using the Scientific Python Development Environment. The model code is freely available on GitHub: …


Rapid Assesment Of Aquatic Insect Diversity And Abundance Used To Evaluate The Quality Of Stream Restoration, Kaleb Stephen Kindoll Apr 2023

Rapid Assesment Of Aquatic Insect Diversity And Abundance Used To Evaluate The Quality Of Stream Restoration, Kaleb Stephen Kindoll

2023 Midwest Ecology & Evolution Conference

Stream and wetland restoration activities seek to improve the function of aquatic ecosystems. Measurement of the diversity and abundance of aquatic insects are commonly used to evaluate the success of restoration efforts, but these measurements are often very time consuming. In this study, we attempt to construct an efficient method that can be used to rapidly assess the diversity and abundance of aquatic insects as a measure of the quality of stream restoration. We suspended uniform sized pieces of cardboard paper coated with adhesive to trap insects in three different environments: one restored and two unrestored streams with similar characteristics. …


Histological Evidence For The Therapeutic Effect Of Chitosan Nanofibrous Dressing On Acute Skin Wounds In A Rat Model, Mahboubeh Ghanbari, Sayed Ahmadreza Razian, Sara Cartwright, Yury Salkovskiy, Jason Mactaggart, Mark A. Carlson Mar 2023

Histological Evidence For The Therapeutic Effect Of Chitosan Nanofibrous Dressing On Acute Skin Wounds In A Rat Model, Mahboubeh Ghanbari, Sayed Ahmadreza Razian, Sara Cartwright, Yury Salkovskiy, Jason Mactaggart, Mark A. Carlson

UNO Student Research and Creative Activity Fair

Introduction: Large-area skin traumas, such as thermal burns, are among the most severe health issues that decrease patients’ quality of life and burden healthcare systems. The CDC estimates that there are 1.1 million burns requiring medical attention each year, with more than 20,000 cases involving at least 25% of the body surface, resulting in 4,500 deaths. In addition, about 10,000 people die from burn-related infections. A promising solution to alleviate this problem is using wound dressings based on biopolymers with inherent wound healing properties and biodegradability. One of these biopolymers is chitosan, which is derived from arthropod shells and exhibits …


Modularity And Boolean Network Decomposition, Matthew Wheeler Nov 2022

Modularity And Boolean Network Decomposition, Matthew Wheeler

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


The Nonlinearity Of Regulation In Biological Networks, Santosh Manicka, Kathleen Johnson, Michael Levin, David Murrugarra Nov 2022

The Nonlinearity Of Regulation In Biological Networks, Santosh Manicka, Kathleen Johnson, Michael Levin, David Murrugarra

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modularity In Gene Regulatory Networks, Mehak Kapoor, Claus Kadelka Nov 2022

Modularity In Gene Regulatory Networks, Mehak Kapoor, Claus Kadelka

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Inferring Dynamics Of Biological Systems, Tracey G. Oellerich May 2022

Inferring Dynamics Of Biological Systems, Tracey G. Oellerich

Biology and Medicine Through Mathematics Conference

No abstract provided.


Machine Learning-Based Risk Factor Analysis And Prevalence Prediction Of Intestinal Parasitic Infections, Ahmet Ay Nov 2021

Machine Learning-Based Risk Factor Analysis And Prevalence Prediction Of Intestinal Parasitic Infections, Ahmet Ay

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Identification Of Control Targets In Boolean Networks Via Computational Algebra, Alan Veliz-Cuba Nov 2021

Identification Of Control Targets In Boolean Networks Via Computational Algebra, Alan Veliz-Cuba

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Building Model Prototypes From Time-Course Data, David Murrugarra, Alan Veliz-Cuba Nov 2021

Building Model Prototypes From Time-Course Data, David Murrugarra, Alan Veliz-Cuba

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Chemoimmunotherapy Treatment Strategies On A Mathematical Model Of Cancer Evolution, Sandra M. Lopez, Yolocuauhtli Salazar, Paul A. Valle Nov 2021

Chemoimmunotherapy Treatment Strategies On A Mathematical Model Of Cancer Evolution, Sandra M. Lopez, Yolocuauhtli Salazar, Paul A. Valle

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Mathematical Model Describing The Behavior Of Biomass, Acidity, And Viscosity As A Function Of Temperature In The Shelf Life Of Yogurt, Manuel Alvarado, Paul A. Valle, Yolocuauhtli Salazar Nov 2021

Mathematical Model Describing The Behavior Of Biomass, Acidity, And Viscosity As A Function Of Temperature In The Shelf Life Of Yogurt, Manuel Alvarado, Paul A. Valle, Yolocuauhtli Salazar

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Neural Network Controller Vs Pulse Control To Achieve Complete Eradication Of Cancer Cells In A Mathematical Model, Joel A. Quevedo, Sergio A. Puga, Paul A. Valle Nov 2021

Neural Network Controller Vs Pulse Control To Achieve Complete Eradication Of Cancer Cells In A Mathematical Model, Joel A. Quevedo, Sergio A. Puga, Paul A. Valle

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


The Role Of Mathematics In 21st Century Medicine, Reinhard Laubenbacher Nov 2021

The Role Of Mathematics In 21st Century Medicine, Reinhard Laubenbacher

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.