Systems Biology Commons^™

Msis-Kadelka: Modularizing The Control Search For Biological Systems, David Murrugarra

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Msis-Kadelka: Algebraic Methods For Inferring Discrete Models Of Biological Networks, Brandilyn Stigler

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Msis-Kadelka: Canalization Reduces The Nonlinearity Of Regulation In Biological Networks, Claus Kadelka, David Murrugarra

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Systems Network Analysis Of Protein Interaction Network (Pin) For Deducing Molecular Mechanistic Action Of Bap Induced Carcinogenesis, Anukriti ., Anupam Dhasmana, Uma Bhardwaj

Research Symposium

Background: Benzo[a]pyrene (BaP), a polycyclic aromatic hydrocarbon, has been placed in group 1 by IARC which indicates that it is a potential carcinogen to human beings. It has shown tumorigenic properties in approximately all animal model systems. In the current study, we have tried to identify the most probable biomolecular targets of BaP using systems biology approach.

Method: All the proteins that interact with BaP were extracted from T3DB. STRING-db was used to generate the Protein- protein interaction network (PPIN). Various apps of cytoscape software were used for network analysis, modulation and GO enrichment analysis. By developing biokinetic …

Modeling Nonsegmented Negative-Strand Rna Virus (Nnsv) Transcription With Ejective Polymerase Collisions And Biased Diffusion, Felipe-Andres Piedra

Research Symposium

Background: The textbook model of NNSV transcription predicts a gene expression gradient. However, multiple studies show non-gradient gene expression patterns or data inconsistent with a simple gradient. Regarding the latter, several studies show a dramatic decrease in gene expression over the last two genes of the respiratory syncytial virus (RSV) genome (a highly studied NNSV). The textbook model cannot explain these phenomena.

Methods: Computational models of RSV and vesicular stomatitis virus (VSV – another highly studied NNSV) transcription were written in the Python programming language using the Scientific Python Development Environment. The model code is freely available on GitHub: …

Histological Evidence For The Therapeutic Effect Of Chitosan Nanofibrous Dressing On Acute Skin Wounds In A Rat Model, Mahboubeh Ghanbari, Sayed Ahmadreza Razian, Sara Cartwright, Yury Salkovskiy, Jason Mactaggart, Mark A. Carlson

UNO Student Research and Creative Activity Fair

Introduction: Large-area skin traumas, such as thermal burns, are among the most severe health issues that decrease patients’ quality of life and burden healthcare systems. The CDC estimates that there are 1.1 million burns requiring medical attention each year, with more than 20,000 cases involving at least 25% of the body surface, resulting in 4,500 deaths. In addition, about 10,000 people die from burn-related infections. A promising solution to alleviate this problem is using wound dressings based on biopolymers with inherent wound healing properties and biodegradability. One of these biopolymers is chitosan, which is derived from arthropod shells and exhibits …

Modularity And Boolean Network Decomposition, Matthew Wheeler

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

The Nonlinearity Of Regulation In Biological Networks, Santosh Manicka, Kathleen Johnson, Michael Levin, David Murrugarra

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Modularity In Gene Regulatory Networks, Mehak Kapoor, Claus Kadelka

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Inferring Dynamics Of Biological Systems, Tracey G. Oellerich

Biology and Medicine Through Mathematics Conference

No abstract provided.

Machine Learning-Based Risk Factor Analysis And Prevalence Prediction Of Intestinal Parasitic Infections, Ahmet Ay

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Identification Of Control Targets In Boolean Networks Via Computational Algebra, Alan Veliz-Cuba

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Building Model Prototypes From Time-Course Data, David Murrugarra, Alan Veliz-Cuba

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Mathematical Model Describing The Behavior Of Biomass, Acidity, And Viscosity As A Function Of Temperature In The Shelf Life Of Yogurt, Manuel Alvarado, Paul A. Valle, Yolocuauhtli Salazar

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Neural Network Controller Vs Pulse Control To Achieve Complete Eradication Of Cancer Cells In A Mathematical Model, Joel A. Quevedo, Sergio A. Puga, Paul A. Valle

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Chemoimmunotherapy Treatment Strategies On A Mathematical Model Of Cancer Evolution, Sandra M. Lopez, Yolocuauhtli Salazar, Paul A. Valle

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

The Role Of Mathematics In 21st Century Medicine, Reinhard Laubenbacher

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Reconstructing Mathematical Models With Chaotic Attractors Via Genetic Algorithms, Luis A. Ramirez Islas, Paul A. Valle

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Perivascular Adipose Tissue In Relation To Diet, Thermogenesis And Cardiovascular Health, Ginger Paquette, Caitlin Stieber, Ashely Soucy, Benjamin Tero, Lucy Liaw

Thinking Matters Symposium

Adipose tissue is a diverse and crucial component to vascular health due to its role in energy storage and heat production. The primary function of white adipose tissue (WAT) is energy storage while the function of mitochondria-rich brown adipose tissue (BAT) is heat production. Perivascular adipose tissue (PVAT), which surrounds blood vessels, contains both WAT and BAT adipocytes. Dietary calorie restriction is associated with increased lifespan with decreased adiposity. Increased prevalence of WAT-like PVAT, due to high-fat diets and obesity, leads to increased metabolic disfunction and cardiovascular-disease. We used a calorie-restriction model in C57BL6/J mice to test the hypothesis that …

Estimating The Number Of Discrete Models Of Biological Networks, Brandilyn Stigler

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Mathematical Modelling And In Silico Experimentation To Estimate The Quantity Of Covid-19 Infected Individuals In Tijuana, México, Karla A. Encinas, Luis N. Coria, Paul A. Valle

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Coping With Stress: The Caulobacter Approach, Bronson R. Weston, Yang Cao, John J. Tyson

Biology and Medicine Through Mathematics Conference

No abstract provided.

A Phosphoinositide-Based Model Of Actin Waves In Frustrated Phagocytosis, Marco A. Avila Ponce De Leon

Biology and Medicine Through Mathematics Conference

No abstract provided.

Mathematics Saves Lives: Models And Signals Enabling Medicine And Biology, Raina Robeva

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Network Reconstruction Using Computational Algebra And Gene Knockouts, Matthew Macauley

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Petri Nets As A Unifying Tool To Link Physiologically Based Toxicokinetic (Pbtk) Models To Adverse Outcome Pathways (Aops), Ian Edhlund

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Transient Dynamics Of Infection Transmission In An Intensive Care Unit, Christopher Short, Matthew S. Mietchen, Eric T. Lofgren

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Using Canalization For The Control Of Discrete Networks, David Murrugarra

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Generation Of Nonlinear-Differential-Equations System From A Model Of Boolean Relationships In Arabidopsis Salt Stress Network, Renee Dale

Biology and Medicine Through Mathematics Conference

No abstract provided.

Dynamic Modeling And Stochastic Simulation Of Metabolic Networks, Emalie Clement

UNO Student Research and Creative Activity Fair

Throughout our current generation, scientific studies, with the help of increased technological methods, have enabled the investigation of biology at nanoscale levels. Nevertheless, such systems necessitate the use of computational methods to comprehend the complex interactions occurring. Traditionally, dynamics of metabolic systems are described by ordinary differential equations producing a deterministic result which negates the intrinsic heterogeneity of intracellular systems. More recently, stochastic modeling approaches have gained popularity with the capability of providing more realistic outcomes. Yet, solving stochastic algorithms tend to be computationally intensive processes. Employing the queueing theory, an approach commonly used to evaluate telecommunication networks, reduces the …