Animal Experimentation and Research Commons^™

Comparative Potency Testing Of Diphtheria Toxoid In Guinea Pigs And Mice For In-House Diphtheria-Tetanus-Pertussis And Diphtheria-Tetanus Vaccines, Wanlop Leeden, Supanee Ummalukacholk, Orawin Mangkhaladul, Eakachai Prompetchara

The Thai Journal of Pharmaceutical Sciences

Background: Diphtheria remains endemic in parts of Thailand and continues to threaten unvaccinated populations. To strengthen vaccine self-sufficiency, the Government Pharmaceutical Organization has developed in-house diphtheria–tetanus–pertussis (DTP) and diphtheria– tetanus (dT) vaccines. Potency testing of diphtheria toxoid is traditionally performed in guinea pigs; however, limitations in animal availability, cost, and logistics have prompted evaluation of alternative models.
Objectives: To compare diphtheria toxoid potency estimates of in-houseproduced DTP and dT vaccines using guinea pigs and mice, followed by a Vero cell-based toxin neutralization assay, and to assess the suitability of mice as an alternative model for potency testing.
Materials and Methods: …

Fish Tissue Digestion And Microplastic Polymer Identification Protocol Using Open-Source Ftir Database, Shawn L. Kissinger, Vick-Ariel Privert, Jason Bystriansky, Kyle A. Grice

DePaul Discoveries

Microplastic (MP) contamination in aquatic ecosystems poses significant concerns for environmental and public health, as seafood represents a critical food source worldwide. Despite increasing evidence of MP presence in marine organisms, efficient and accessible detection methods remain essential for characterizing contamination patterns and informing regulatory frameworks. This study extracted MPs from brain, gill, intestine, liver, and muscle tissues of gilt-head bream (Sparus aurata) and European sea bass (Dicentrarchus labrax), two commercially important species from the Gulf of Cádiz, Spain, using a NaOH–HNO₃ chemical digestion protocol. Isolated particles were characterized by Fourier Transform Infrared (FTIR) spectroscopy, with …

Near-Infrared Spectroscopy For Monitoring Bovine Respiratory Syncytial Virus Infection In Experimentally Challenged Calves, Erin Blanchard, Jelena Muncan, Grace Beddingfield, Cassandra Barber, Florencia Meyer, Santiago Cornejo, Merrilee Thoresen, Amelia Woolums, Carrie Vance

Endeavors: Mississippi State Undergraduate Research Journal

Bovine respiratory disease (BRD) is a multifactorial disease complex that causes significant economic loss in the cattle industry. Bovine respiratory syncytial virus (BRSV), one of the primary viruses included in BRD, primarily targets the lower respiratory tract and causes a wide variety of subclinical and clinical signs. Current diagnosis techniques require off-site laboratory testing, creating delays that allow BRSV to spread through herds and highlighting the need for rapid diagnostic methods. The objective of the study was to evaluate near-infrared spectroscopy as a diagnostic tool for BRSV detection across varying infection severities. Twenty-two Holstein bull calves were reared in research …

Napier Grass (Pennisetum Purpureum) Meal Modulates Growth Efficiency, Gut Morphology, And Systemic Health In Broiler Chickens, Eric Lim Teik Chung, Yee Lyn Ong, Nazri Nayan, Muhamad Faris Ab Aziz, Faez Firdaus Abdullah Jesse, Faizal Andri, Arissara Sopawong

The Thai Journal of Veterinary Medicine

Grass and leaf meals, which include vital phytocompounds, have the potential to be a natural and safe alternative to antibiotics in the poultry industry. Therefore, this study aims to assess Pennisetum purpureum leaf meal and its phytocompounds on the health performances of colored-broilers. A total of 216 unsexed Sasso chicks were assigned to six diet groups. The negative control (T1) received a commercial basal diet without antibiotics, while the positive control (T2) received the same diet with oxytetracycline (100 mg/kg). Groups T3 to T6 received no antibiotics and included P. purpureum meal at 1.25, 2.50, 3.75, or 5.00 grams per …

Water Sources And Livelihood Choices Among Pastoralist Households In Monduli District, Tanzania, Fredrick Alleni Mfinanga, Jacqueline Temba, Monica F. Timbuka

Journal of Humanities and Social Sciences

This paper investigates the association between types of water sources for livestock and livelihood choices of pastoralist households in semi-arid areas of Monduli District, Tanzania. Specifically, it aims to examine the influence of the types of water sources for livestock on livelihood diversification of pastoralist households. Using a mixed research methods approach, the data were collected from 367 households through three methods: surveys, interviews, and focus group discussions. The quantitative data were analysed using descriptive statistics such as frequencies and counts, and inferential statistics, Chi-square tests and correlation, while the qualitative data were analysed using content analysis. The findings revealed …

Beta-Casomorphin7 Detection In Milk From Dairy Species And Beta-Casein Protein Characterization In Cattle From Selected Provinces In The Philippines, Angelo M. Tapia, Cynthia R. Oliveros Maria, Queennie Hope D. Umipon, Hazel Marie E. Nicolas, Naoya Ogawa, Yasuyuki Kitaura

The Philippine Agricultural Scientist

This study was conducted to detect β-casomorphin7 (BCM7) in dairy animals and to characterize the β-casein (CSN2) genotype among dairy cattle breeds in the Philippines. A total of 59 dairy animals, composed of 35 cattle (12 Holstein Sahiwal [HS16 Jersey × Holstein Friesian [JHF], and 7 Siquijor Native Cattle [SNC]), 15 buffaloes (Bulgarian Murrah and Brazilian Murrah), and 9 goats (Saanen and Anglo-Nubian) were collected with milk samples. Milk protein was extracted and subjected to high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) analysis after stimulated gastrointestinal digestion. BCM7 was detected in cattle with an average concentration of 0.322 + 0.080, whereas …

Just "Beet" It? A Comparison Of Road Salt Effects On The Life History Of Daphnia Magna, Koby Sellner

The Journal of Purdue Undergraduate Research

In areas that experience snow and ice, deicing reagents such as road salts are often used on roads to promote safer driving conditions. However, road salts run off into local vegetation, soil systems, and (my focus) freshwater systems. The impacts of excess salt and chloride in freshwater have been studied extensively on a broad diversity of organisms under different conditions, but previous studies have rarely used different types of road salts. Zooplankton are primary consumers in many freshwater systems, feeding on phytoplankton and serving as prey for predator species higher in the trophic chain. These animals generally are impacted negatively …

Prediction Equations For In Vitro Nutrient Utilization Of Bakery Byproducts For Pigs, Junghyun Oh, Hansol Kim, Yoon Soo Song, Noa Park, Youl-Chang Baek, Chung Hyun Kim, Beob Gyun Kim

The Philippine Agricultural Scientist

This study aimed to develop equations for predicting the in vitro ileal disappearance (IVID) of dry matter (DM) and crude protein (CP) and in vitro total tract disappearance (IVTTD) of DM and organic matter (OM) in bakery byproducts based on their chemical composition, including neutral detergent fiber (NDF). Ten sources of bakery byproducts were tested for IVID and IVTTD of nutrients using a 2-step procedure simulating the digestion and absorption in the stomach and small intestine and a 3-step procedure simulating the digestion and absorption in the stomach, small intestine, and large intestine of pigs. The prediction models for IVID …

Factors Affecting Beef Average Daily Gain And Carcass Traits In Smallholder Farms In Thailand, China Supakorn, Sumalee Supant, Warinthorn Maneerat, Ya-Shiou Chang, Monticha Putsakhum

The Philippine Agricultural Scientist

This study examined the effects of farm management, body weight, fattening duration, breed, and estimated age on average daily gain (ADG) and meat quality traits, such as hot carcass weight (HCW) and dressing percentage (DP). The dataset comprised 3,286 steers from the Livestock Cooperative in Sakon Nakhon province, Thailand, spanning 10 yr (from 2013 to 2023). The mean initial and slaughter weights were 392.92 ± 29.18 kg and 600.75 ± 60.73 kg, respectively. The ADG during the fattening period was 0.95 ± 0.17 kg/d, while HCW and DP averaged 328.86 ± 40.79 kg and 54.75 ± 1.41%, respectively. The beef …

Evaluation Of Semen Characteristics And The Impact Of Storage Time In Dong Tao And Ho Indigenous Chickens, Phan Nhan, Nguyen Thi My Phuong

The Philippine Agricultural Scientist

This study aimed to evaluate the semen quality of 2 indigenous Vietnamese chicken breeds, Dong Tao and Ho, and to assess their reproductive potential for breeding and conservation programs. Semen samples were collected from 10 roosters of each breed and analyzed for macroscopic and microscopic traits. The results indicated that both breeds exhibited semen quality within acceptable physiological ranges. Mean semen volume was 0.47 mL in Dong Tao and 0.48 mL in Ho roosters; pH values were 7.47 and 7.42, respectively. Semen color scores (2.39 vs. 2.35), sperm concentrations (2.11 vs. 1.92 × 109/mL), and mass activity scores (3.79 vs. …

Enhancing Topical Drug Delivery Of Apremilast Through Niosomal Gel Formulation: Ex Vivo Skin Permeation And In Vivo Evaluation For Psoriasis, Megha Shyam Matlapudi, Anka Rao Areti, Yukti Jaiswal, Veeresh Bantal, Raghavender Medishetti

The Thai Journal of Pharmaceutical Sciences

Background: Psoriasis is a dynamic and chronic disease characterized by inflammatory changes and an increased rate of keratinocyte proliferation leading to the formation of erythematous scleroderma plaques with a silvery sheen. The existing therapies come with shortcomings in terms of effectiveness and leave behind a trail of side effects. Hence, there is a need of alternative therapeutic measures. Objectives: This study aimed to assess the therapeutic potential of Apremilast Niosomal Gel (APR Nio Gel) in treating psoriasis, comparing its effectiveness with conventional gel (APR Gel) and oral suspension (APR Oral) formulations. Materials and Methods: Apremilast niosomes were prepared by thin …

Exploring The Therapeutic Potential Of Trigonella Foenum-Graecum Extract-Loaded Transferosomal Gel In Freund's Complete Adjuvant-Induced Rat Models., Vandana Singh Ms., Hema Arya Ms., Bhavana Singh Dr., Koushal Dhamija Mr., Preeti Singh Dr., Gautam Kumar Dr.

Chulalongkorn Medical Journal

Abstract:

Background: Rheumatoid arthritis (RA) is a debilitating autoimmune disorder characterized by inflammation and joint damage.

Objective: This study aimed to evaluate the antiarthritic activity of Trigonella foenum-graecum (TFG) Transferosomal gel in a Freund’s adjuvant-induced arthritic rat model and compare it with Diclofenac gel, a standard anti-inflammatory drug.

Methods: Arthritis was induced in rats by injecting a 0.1 mL (1mg/ml) CFA suspension into the left hind foot in the subplantar region, allowing them to develop arthritis for 21 days.

Results: Arthritis induction led to a significant increase in paw volume, indicative of inflammation. Treatment with both TFG-transferosomal gel and Diclofenac …

External Jugular Vein Catheterization Technique For Continuous Blood Sampling In Gilts, Preechaphon Taechamaeteekul, Yosua Kristian Adi, Chutikan Srisang, Pirada Virankabutra, Natchanon Dumniem, Jinda Singlor, Padet Tummaruk

The Thai Journal of Veterinary Medicine

External jugular vein blood collection is common in gilts and sows, but continuous sampling for hormonal and pharmacokinetic research requires catheterization. The standard protocol has remained largely unchanged for nearly 40 years. This study aimed to develop a modified external jugular vein catheterization technique in gilts. Ten gilts (72.0 ± 3.4 kg) underwent surgery under general anesthesia after 12-hour fasting. Sedation was induced with intramuscular Xylazine (4.4 mg/kg) and Tiletamine–Zolazepam (2.2 mg/kg), followed by intravenous Thiopental sodium (10 mg/kg). Once anesthetized, gilts were placed in dorsal recumbency, and the external jugular fossa was prepared under sterile conditions. A 10 cm …

Antibiotic Resistome, Mobile Genetic Elements, And Virulence Profile Of Multidrug-Resistant Enterobacteriaceae Isolated From Healthy Philippine Native Chicken As Revealed By Analysis Of Whole Genome Sequence, Alvin P. Jimenez, Grignard James R. Buday, Rina B. Opulencia

The Philippine Agricultural Scientist

Gram-negative bacteria, particularly Enterobacteriaceae, acquire antibiotic resistance via horizontal transmission of resistance genes in poultry farms that give rise to multidrug-resistant (MDR) strains. The presence of MDR strains that are potentially pathogenic and zoonotic poses a concern to animal and human health. The aims of this study were to isolate MDR, potentially pathogenic Enterobacteriaceae from Philippine native chicken (PNC) and to analyze the genome of a representative MDR isolate to gain insights into the mechanisms, acquisition, and transmissibility of antibiotic resistance genes (ARGs). Cloacal swabs from PNC were used to isolate putative Salmonella that were then tested for antimicrobial …

Local Tissue Damage Treatment Of Snake Venom, Suchitra Khunsap

The Thai Journal of Veterinary Medicine

Local tissue damage caused by snake envenomation was a medical problem that caused morbidity and mortality for more than a decade, with no defined treatment guidelines. Nowadays, antivenom is the primary treatment for snakebite, which substantially reduces systemic venom but not significantly reducing local symptoms. We compiled a list of local damage therapies, including antivenom medication, surgery and skin grafting, small molecule medicines, and alternative therapies. Although each was not approved as a standard treatment, it may be a treatment option for tissue damage caused by snake venom. However, antivenoms and most resistant compounds may not be the best strategy …

Effectiveness Of Maternal Bovine Appeasing Substance Administered To Newly Received, High-Risk Stocker Calves, Elle Johnston, Rosie Whittle, Robin Cheek, Beth Kegley, Jeremy Powell, Shawna Weimer

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Stocker cattle purchased at auction can be susceptible to disease due to the stressors associated with the auction process and are referred to as “high-risk.” The objective of this study was to determine the efficacy of a maternal bovine appeasing substance, FerAppease^®, on the growth performance, health, and behavior of stocker cattle. Male beef calves (n = 80) were purchased at auction and transported to the University of Arkansas System Division of Agriculture Savoy Research Complex Beef Stocker Unit. On day 0, bulls were castrated, and steers and bulls were assigned to 8 pens (n = 10 calves/pen; …

Effect Of Traditional Versus Fenceline Weaning On Lamb Stress, Emma N. Sutton, Kenneth P. Coffey, Eva Wray, Derico Setyabrata, Bryan Kutz, Shawna Weimer

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Stress in sheep can negatively affect productivity and increase their susceptibility to illness and parasites. The traditional method of weaning lambs is the abrupt separation of lambs from their dams. An alternative method of weaning, fenceline weaning, where offspring are separated from their dams by a single fence but retain visual and auditory contact, has been found to reduce stress in cattle and may also reduce stress in sheep. The objectives of this study were to evaluate body weights, fecal egg counts, and behavior to determine if traditional or fenceline weaning has lower stress associated with weaning in lambs. The …

Development Of An Injectable Chitosan-Based Bioink For Enhanced Bone Fracture Healing Via Msc-Derived Osteogenesis, Zeina H. Adel, Jana A. Hassan, Hala H. Muhammed, Haneen M. Elsaeid, Raghad M. Nasr, Ahmed M. Deghidy

BAU Journal - Science and Technology

Worldwide, bone fractures are a major public health concern and, there is an urgent requirement to create new treatments to accelerate the rate of the bone healing process. This research mainly relies on creating a hydrogel that satisfies the bone marrow mesenchymal stem cells (BM-MSCs) and makes it a suitable medium to differentiate into osteogenic cells. We combine the BM-MSCs with a chitosan polymer-based hydrogel, infused with PVA to enhance bone healing, this unique mixture forms " Bioink ". We induced a closed fracture model in the rat's right humerus, followed by injection of a single dosage of bioink. On …

Production Objectives And Trait Preferences Of Smallholder Farmers In The Philippines: Implications For Designing Breeding Schemes Utilizing Indigenous Swine Genetics, Joy Banayo, Kathlyn Louise Manese, Kaito Furusho, Madeline Kingan, Justine Ayomen, Marcelino Saliw-An, Karina Marie Nicolas, Kayvin Joel Petipit, Dorothy Pagbilao, Vea Roven Arellano, Rene Santiago, Flomella Caguicla, Arnolfo Monleon, Giselle Perlas, Giselle Perlas, Rea Palma Ortego, Sharon Singzon, Agapita Salces, Takahiro Yamagata

The Philippine Agricultural Scientist

Profit maximization is not the only production objective in farming. For smallholder farms worldwide, family sustenance often takes priority, with production being viewed more as savings-oriented than market-oriented. Furthermore, market pressures can lead to the mismanagement of indigenous livestock resources, increasing their risk of genetic erosion. To ensure the long-term conservation of the Philippine native pig, this study aimed to determine the various types of native pig farmers and define the intervention strategies for each type. A total of 432 native pig farmers representing seven provinces in the Philippines (Benguet, Kalinga, Isabela, Nueva Vizcaya, Quezon, Marinduque, and Eastern Samar; n …

Growth And Mobility Of Physella Acuta Under Individual And Combined Acetaminophen And Salinity Exposure, Rhea Wilder, Jason Doll, Daniel Elias

Journal of the South Carolina Academy of Science

Global climate change, driven by rapid population growth and anthropogenic activities, presents an urgent challenge to aquatic ecosystems. Salinity intrusion threatens water quality and availability for human and wildlife populations. At the same time, due to the demand for pharmaceuticals, these pollutants are increasingly detected in freshwater environments, with acetaminophen being one of the most prevalent. This research analyzed the individual and combined effects of salinity (2.5 g/L) and acetaminophen (488 μg/L) on Physella acuta. Overall, we observed reduced snail movement under elevated salinity and no effects on growth or movement with acetaminophen alone or in combination with salinity. …

Boar Sperm Performance In Polystyrene Transport Cool Box Under Various Storage Conditions And Holding Times [Rsearch Note], Santiago T. Peña Jr., Bianca Therese P. Ymas, Mark Edd B. Janier, Heherson A. Luza

The Philippine Agricultural Scientist

When transporting highly valuable boar semen samples over long distances, it is crucial to ensure that boar semen is stored ideally at approximately 15 – 17°C to minimize the impact of cold shock and oxidative damage on sperm quality. This study evaluated the performance of a commercially available semen and embryo polystyrene transport cool box, BotuFLEX®, in preserving the quality of extended boar semen under different storage conditions and holding times. Boar ejaculates were extended at 1:1 or 1:3 using a commercial mid-term extender, stored in a BotuFLEX® semen cool box, and examined 24 vs. 48 h thereafter (Experiment 1; …

Microplastic Accumulation In The Marsh Periwinkle (Littoraria Irrorata), Sarah Keaton, Hannah Lukhard, Eli Windy, Manar Hasan

DePaul Discoveries

Contamination of oceans by microplastics (mm) currently poses a major threat to aquatic and terrestrial ecosystems worldwide. Recent attention towards this issue has raised questions about the extent to which microplastics have accumulated in the environment, and has led to an increase in studies on the effects of microplastics in various organisms. However, levels of contamination in protected natural areas are still largely unexplored, yet can offer an important empirical perspective on the issue. In addition, little is known about the potential effects of microplastics on behavior in the field. This research was conducted within the protected ACE Basin National …

Baseline Characterization Of Semen From Philippine Native Chickens: Banaba, Joloano And Paraoakan, Darcy Pamulaklakin, Carla Alilie Junsay, Consuelo Amor Estrella, Percival Sangel

The Philippine Agricultural Scientist

The study aimed to characterize and establish baseline data on the quantity and quality of fresh avian semen utilizing a sample of Philippine native roosters. Twenty-two heads each were acquired from breeds Banaba, Joloano, and Paraoakan. The baseline data analysis revealed significant variations in semen volume among different genetic groups, with Banaba displaying the highest volume, followed by Joloano and Paraoakan. Banaba also exhibited the highest semen pH value of 7.27 when compared to the other two genetic groups (P < 0.05). Across various genetic groups of native chickens, the majority of semen samples demonstrated a thick and creamy consistency and color (42.6%), followed by thin and creamy (32.9%), with a statistical significance of P < 0.05. Furthermore, variations in sperm concentration were observed among genetic groups, with Paraoakan having the highest sperm concentration, followed by Banaba and Joloano (P < 0.05). When the semen from Banaba and Joloano native roosters were extended in Ringer’s solution, it exhibited good motility, with more than 50% of spermatozoa in motion, even after six hours of extension. In contrast, the pooled extended semen from Paraoakan native roosters displayed poor motility, particularly after eight hours of extension (P < 0.05). The study also showed that storage temperatures did not significantly affect all the sperm quality parameters of Banaba and Joloano. However, for Paraoakan, samples stored at low temperatures of 5 – 10ºC had significantly higher percent motile and progressive sperm, and lower percent static sperm than those stored at room temperature (22 – 25ºC) (P < 0.05).

A Comparison Of Larvicide And Garlic Mineral Salts On Horn Fly Populations, Kristina N. Dees, Benjamin J. Schrag

SACAD: Scholarly Activities

For this research project, we studied three separate pastures containing Fort Hays State University’s Holstein cows. One pasture was our control group, with no horn fly protection applied. Another pasture had cattle that were fed with garlic in their mineral salts, an all-natural horn fly prevention method. Our final pasture contained cows sprayed with a larvicide. This was a single-blind study, meaning I did not know which pasture had what treatment, but my professor knew. Throughout the late summer and early fall of 2023, we went out to each pasture and took pictures of ten cows per pasture. Then, using …

Eristalis Tenax Movement Behavior In Response To Light, Temperature, And Food, Jeffery J. Zheng, Zdena M. Janderova, Jason D. Lang

Georgia Journal of Science

Drone flies, Eristalis tenax (Diptera: Syrphidae), are important generalist pollinators and visit flowers globally that range widely in color. The flies’ photoreceptors allow them to sense light wavelengths between 300-600 nm and E. tenax exhibit a positive phototactic response. To understand the effects of light on E. tenax movement, we conducted two-choice behavioral tests to determine their phototactic response to different wavelengths of light across the spectrum (ultraviolet to red light, plus full spectrum white light). The drone flies moved most and quickest toward sunlight, with almost twice the percentage of flies moving toward sunlight than toward black and …

Quantifying Wild Pig Disturbance In Pastures And Wetlands Using Unmanned Aerial Vehicle-Derived Imagery, Wesley M. Anderson, Bethany Wight, Raoul K. Boughton

Human–Wildlife Interactions

The use of unmanned aerial vehicles (UAVs) for agricultural and environmental research has increased markedly in recent years, and a key application has been to conduct damage assessments. Invasive wild pigs (Sus scrofa) cause both agricultural and environmental damage, and past studies have utilized UAVs to quantify this damage. Each methodology has advantages, but they also have drawbacks such as high rates of damage omission or reliance upon a near-infrared camera, which may be prohibitively expensive for some land managers and scientists. Our objective was to develop a methodology that could be easily implemented to conduct wild pig …

Digestible And Metabolizable Energy In Ground Yellow Corn, Rice Bran, And Copra Meal Fed To 10 To 15 Kg Philippine Native Pigs (Benguet Strain), Mary Arnel D. Garcia

The Philippine Agricultural Scientist

The experiment was conducted to determine the digestible energy (DE), metabolizable energy (ME), and apparent total tract digestibility (ATTD) of gross energy in ground yellow corn, rice bran, and copra meal when fed to Philippine native pigs. Nine barrows with an average initial bodyweight of 10 kg and ages ranging from 60 to 75 d old were housed individually in metabolism crates and randomly allotted to a triplicated incomplete 3 × 2 Latin square design with three diets and two periods. A corn-based diet containing 94.89% yellow corn and two diets containing 66.42% yellow corn and 30% rice bran or …

Consolidated Chamber Design And Protocol For Olfactory Conditioning Assay With Drosophila Melanogaster, Sasha Bronovitskiy, Andres Castillo, Michael Yan, Fang Ju Lin

Journal of the South Carolina Academy of Science

The olfactory conditioning assay is widely used in Alzheimer’s disease research to quantify learning and memory in Drosophila melanogaster. The assay tests ability to recall an aversive conditioned stimulus of scent paired with electrical shock when presented a choice between shock-associated and unrelated scents. The T-maze, a commonly used apparatus for olfactory conditioning assays, employs an elevator mechanism to transfer live flies from the shock-delivering training chamber to the scent selection point. This elevator mechanism is known to cause fly casualty. T-mazes are not commercially available and often difficult to reproduce. Other existing variations of olfactory conditioning apparatuses use …

Update – Food & Drug Administration’S Animal Testing Mandate, Andrew N. Rowan

WellBeing News

Following the end of the Second World War, the World Medical Association developed new ethical guidelines regarding research involving human subjects. These guidelines included requirements to obtain informed consent from research subjects but also emphasized the importance of conducting animal research before engaging in human clinical trials and other human research. This principle was included in legislation mandating the FDA to require prior animal research before permitting human trials of new drugs. That mandate was recently eliminated by new US legislation cosponsored by Senators Cory Booker and Rand Paul. The FDA can now encourage non-animal methods and no longer has …

A Critical Look At Wild Pig Elimination: Myths And Facts, Kim M. Pepin, Travis L. Guerrant, Jeremiah L. Psiropoulos, Jeanine T. Neskey, John M. Tomeček, Michael J. Bodenchuk, Janean L. Romines

Human–Wildlife Interactions

Wild pigs (Sus scrofa) are abundant and widely distributed in the United States. They damage crops and pastures, predate livestock and sensitive species, impact ecosystem functions, and damage personal property. To address these issues, some states in the United States are seeking complete elimination. A frequently asked question by stakeholders is: “What portion of the population needs to be removed annually to reach elimination?” The number 70% is widely touted as the answer. There is little scientific evidence to support that this percent annual removal would be needed to achieve elimination, yet 70% has now become a standard …