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Marquette University

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Full-Text Articles in Animal Experimentation and Research

Elucidating The Mechanical, Structural, Functional, And Molecular Mechanisms Involved In Irreversible Vascular Changes In Aortic Coarctation, Brandon Wegter Oct 2017

Elucidating The Mechanical, Structural, Functional, And Molecular Mechanisms Involved In Irreversible Vascular Changes In Aortic Coarctation, Brandon Wegter

Master's Theses (2009 -)

Coarctation of the aorta (CoA) is a constriction of the thoracic aorta and is one of the most common congenital cardiovascular defects. Treatment by surgical correction has saved the lives of thousands of children, but many still have a reduced lifespan due to hypertension. Previous results using our novel rabbit model showed that the current treatment guideline of a 20 mmHg blood pressure gradient (BPG) induces irreversible vascular changes, which persisted despite correction. Preliminary data of the downregulation of natriuretic peptide receptor C (NPR-C) in proximal aortic tissue of human patients with CoA serves as the possible underlying mechanism for …

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A Study Of The Renal Vascular Supply In The Domestic Cat, Elizabeth Rosen May 1946

A Study Of The Renal Vascular Supply In The Domestic Cat, Elizabeth Rosen

Bachelors’ Theses

Studies on the normal and abnormal vascularization of the renal vessels in the domestic cat (felis domestica) indicate the frequency of anomalies that occur, but in most of the studies it is the inferior vena cava that is most often recorded. Among the occasional references to several renal veins or arteries we have Huntington and McClure, Elmer Butler, Gaylord Bates, William Darrach, and C.H. Fortune. Yet no study seems to have been made of individuals of any particular class. A superficial observation seems to indicate a large number of cats used in the laboratory had multiple renal veins. Hence a …

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Histological Study Of The Small Intestine Of The Common Green Snake, Thamnophis Sirtalis, Robert George Stineman Jun 1945

Histological Study Of The Small Intestine Of The Common Green Snake, Thamnophis Sirtalis, Robert George Stineman

Bachelors’ Theses

Although much work has been done histologically with the vertebrates, very little seems to have been done on the intestinal tract of the reptile. This is especially true of the snakes, despite the abundant sources of material. Reptiles are one of the first classes of vertebrates in which there is a distinction made between small and large intestine. Histology textbooks devote only a few lines to the histology of the reptilian small intestine. For this reason it seems that it would be worthwhile to make a detailed study of that portion of the intestinal tract immediately distal to the duodenum …

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The Effect Of Adrenaline Injection On Glycogenolysis And Glycogenesis In Rat Livers, Virginia Mary Zingsheim Feb 1945

The Effect Of Adrenaline Injection On Glycogenolysis And Glycogenesis In Rat Livers, Virginia Mary Zingsheim

Bachelors’ Theses

Present day knowledge concerning the liver is derived from many sources and the accumulation of many methods of investigation. Sugar, which is needed by the body for energy, is stored in the liver as glycogen. Claude Bernard (26), an eminent physiologist, was the first to suspect that carbohydrates were stored in the liver. Faulty glycogen synthesis and hydrolysis results in one of our most widespread diseases, diabetes. Thus, many biochemists and physiologists have tried to find the mechanism of the process, and the primary and secondary facts which affect glycogenesis and glycogenolysis. Although the chemical secretions and hormones of such …

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The Spinal Nerves And Spinal Cord Of The Frog, Laverne A. Penn Sep 1938

The Spinal Nerves And Spinal Cord Of The Frog, Laverne A. Penn

Bachelors’ Theses

The common grass frog, Rana pipiens as wall as the bull frog, Rana catesbiana have served during many decades as material from which both the student of zoology and the investigator in biological problems have gathered valuable information about the anatomy and physiology of the common systems. Among these systems the central, peripheral, and sympathetic nervous system plays a coordinating role, because of the ramifying nature of its organization. It is the purpose of this thesis to investigate the gross and histological structure of these branches known as spinal nerves. When one inspects the literature on the nervous system of …

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The Lungs And Respiration In The Frog, Peter P. Strassburg Jun 1938

The Lungs And Respiration In The Frog, Peter P. Strassburg

Bachelors’ Theses

In a wide sense, respiration is sometimes defined as the gaseous exchange constantly taking place between an organism and its environment. Essentially it is concerned with the intake of oxygen and the output of carbon dioxide but it also includes any other gas exchange that might occur. Small organisms take oxygen directly from the air or from the watery medium surrounding them into all parts of their structures. They also give off carbon dioxide from all their parts directly into the surrounding medium. They can do this successfully because they are small enough to have every cell in direct or …

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Kidney Of The Frog, Felix Taubman May 1938

Kidney Of The Frog, Felix Taubman

Bachelors’ Theses

The frog has been used exclusively in both high school and college as the main source of experimental biological and zoological studies. Because it is so easily obtained and so finely adapted to our purposes, we chose it as the specimen upon which to do our thesis work. Much has been done experimentally on the kidneys with the frog. The purpose of this thesis is to present a general view of the external and microscopic anatomy of the frog kidney and with this as a groundwork to present the problems of secretion; whether secretion is carried on by the renal …

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