Research Methods in Life Sciences Commons^™

Bluebird Bait: Quantifying The Attraction Of Ectoparasites To Nestling Eastern Bluebirds (Sialia Sialis), Ella Grace Bollinger

ATU Scholars Symposium

Ectoparasites, such as mosquitoes (Culicidae), blackflies (Simuliidae), and biting midges (Ceratopogonidae), have been shown to reduce population viability by lowering post-fledging survival and decreasing the lifetime reproductive success of adult birds. This issue is particularly concerning for songbirds such as the Eastern Bluebird (Sialia sialis) because their nestlings are relatively naked and have limited mobility, making them highly vulnerable to attacks by biting flies. However, the specific mechanisms attracting ectoparasites to nests remain understudied. We hypothesized that biting fly and mosquito abundance would be significantly higher at active Eastern Bluebird nests than that of empty boxes and would increase with …

Consumption Habitats Of Male And Female Lionfish Regarding The Production Of Eggs, Zalyn Baker, Natalie Tipsword, Sam Fisher

Symposium of Student Scholars

The lionfish, scientifically known as Pterois, belongs to the Scorpaenidae family, which is native to the Indo-Pacific Ocean, but has become an invasive species in the Caribbean Sea. First observed in Belize in 2008, lionfish have since become established in the Belize Barrier Reefs. Known for their ability to consume a wide range of species, lionfish compete with native fish for food resources. This invasive species poses a significant threat to the ecosystem due to their venomous spines, aggressive predatory behavior, lack of predators, and high reproductive rate, with lifespans extending up to 30 years. Our study aimed to investigate …

Morph- And Sex-Specific Differences In Corticosterone Of The Arizona Tiger Salamander (Ambystoma Mavortium Nebulosum), Megan Zerger

Scholars Week

Life history morph, sex, and body condition are traits that may influence stress within salamander populations because of differences in physiology and environmental conditions. Given widespread declines and the effects chronic stress can have on amphibian health, it is important to understand within-population drivers of stress and how population level variation may influence population viability. Thus, the objective of our study was to assess how corticosterone varies within the Arizona tiger salamander (Ambystoma mavortium nebulosum) population at the Mexican Cut Nature Preserve. We used a non-invasive skin swabbing method to collect baseline and elevated corticosterone from paedomorph (aquatic …

Development Of A Pd-L1 Pet Imaging Biomarker, Caleb Jack Bridgwater

Posters-at-the-Capitol

Immunotherapy strategies are very promising treatments for cancer patients. Specifically, Immune checkpoint inhibitor therapy focusing on the PD-1/PD-L1 pathway shows long-lasting positive results in many cancer patients. Unfortunately, not all the patients can benefit from this highly effective treatment. Hence, there is a great need for predictive biomarkers. Immunohistochemical (IHC) staining has been used as a way of predicting patient response, yet shows many problems. For example, IHC utilizes an invasive biopsy and sample fixing, which creates an incomplete and delayed picture of the patient’s biochemistry and the tumor microenvironment, consequently ignoring metastases.

The purpose of this study is to …

Studies Of Amino Acid Mutations In Drug Resistance Of The Smo Protein, Eunice Wintona

UNO Student Research and Creative Activity Fair

Smoothened receptor (SMO) is a protein that in humans, is encoded by the SMO gene. A systemic mutation in its binding pocket helps predict the sensitivity of mutant proteins to different drugs. Known as a GPCR-like receptor, it is a component of the hedgehog signaling pathway; a pathway involved in body patterning and the regulation of adult stem cells. An uncontrolled or inappropriate activation of the Hedgehog pathway drives tumor progression in cancers and a number of birth defects. To achieve these goals, the molecular modeling software MOE was used to build small molecules and drug molecules like Vismodegib and …