Research Methods in Life Sciences Commons^™

Ethology And Laboratory Animal Welfare, James A. Cohen

International Journal for the Study of Animal Problems

No abstract provided.

Live Animals In Car Crash Studies, Nancy Heneson

International Journal for the Study of Animal Problems

No abstract provided.

Definition Of The Concept Of ''Humane Treatment" In Relation To Food And Laboratory Animals, Bernard E. Rollin

International Journal for the Study of Animal Problems

The very title of this talk makes a suggestion which must be forestalled, namely the idea that laboratory and food animals enjoy some exceptional moral status by virtue of the fact that we use them. In fact, it is extremely difficult to find any morally relevant grounds for distinguishing between food and laboratory animals and other animals and, far more dramatically, between animals and humans. The same conditions which require that we apply moral categories to humans rationally require that we apply them to animals as well. While it is obviously pragmatically impossible in our current sociocultural setting to expect …

Nsmr: Its Image, Direction And Future, J. Russell Lindsey

International Journal for the Study of Animal Problems

The following speech was presented by Dr. Lindsey, Chairman of the University of Alabama Department of Comparative Medicine, at the Annual Board Meeting of the National Society for Medical Research (NSMR), Chicago, Illinois, November 10, 1979.

Laboratory Animals And Alternatives In The 80'S, Andrew N. Rowan

International Journal for the Study of Animal Problems

No abstract provided.

Animals Are Suffering: Hsus Seeks To End Rabbit Blinding Tests

Close Up Reports

The research industry has long held that the use of animals is the only "reliable" way we have of determining the safety of a cosmetic, drug, or household product. Over the years this belief has served to support scientists as they subjected animals to many tests. The American public has seen little of the massive animal suffering that has taken place in the research labs.

Today, a new debate is taking place. People from all walks of life are asking if all the suffering and death is worth it. Many research scientists have joined the ranks of those who are …

The Public Governance Of Science And Research Animal Welfare, T. E. Malone

International Journal for the Study of Animal Problems

The following is excerpted from a speech given by Dr. Thomas E. Malone, Deputy Director of the National Institutes of Health, at the 26th Annual Meeting of the American Association of Laboratory Animal Scientists (AALAS), Anaheim, California, October 5, 1977.

Live Animals In Car Crash Studies, Nancy Heneson

Experimentation Collection

The scientific rationale for using live animals in car crash studies proceeds from the argument that comparative biomedical and biomechanical data are needed to develop an instrumented dummy, or anthropomorphic test device, which will provide reliable, reproducible information for designing safe cars. The animal studies are thus not really ends in themselves, i.e., they do not supply data which can be readily applied to real situations. Instead, they contribute to a pool of information which is supposed to lead to the perfecting of an experimental subject (the instrumented dummy) which will eventually render the further use of Iive animals unnecessary.

Nsmr: Its Image, Direction And Future, J. Russell Lindsey

Experimentation Collection

The point I wish to emphasize is that NSMR, like all of its predecessors representing the scientific community, has consistently maintained a defensive posture while claiming that a// practices of animal use and care within the biomedical community have been "lily white." In my judgment, this has been a major tactical error because abuses of freedoms to use animals in research too frequently have been and continue to be common knowledge (e.g., Science, Editorial, 1976). NSMR's complete unwillingness to face up to these realities and torespond positively to the public's legitimate concerns has led to the inevitable loss of credibility …

Ethology And Laboratory Animal Welfare, James A. Cohen

Laboratory Experiments Collection

At its annual conference, held this June at Colorado State University in Fort Collins, the Animal Behavior Society (ABS) passed a resolution opposing HR 4805, a bill which would establish a National Center for Alternative Research to develop and coordinate alternative methods of research and testing which do not involve the use of live animals. The ABS, which represents some 1750 North American animal behavior researchers, took issue with the bill on the grounds that: a) it discourages replication of previously-obtained results, b) there are currently no satisfactory substitutes for live animals in behavioral research, c) it would complicate and …

Pain-Infliction In Animal Research, Dorothy Tennov

Experimentation Collection

A summary of research outlining the main sources of pain and stress to animals in laboratories provides the background for the results of a survey conducted by the author on how students feel about experimentation involving animals. The psychological aspects of student reaction to animal experimentation are examined. The conclusion outlines specific recommendations on ways to minimize pain and discomfort of laboratory animals.

Animals In Education: The Use Of Animals In High School Biology Classes And Science Fairs, Heather Mcgiffin, Nancie Brownley

ANIMALS IN EDUCATION is the proceedings of the conference, "The Use of Animals in High School Biology Classes and Science Fairs," held September 27-28, 1979 in Washington, D.C. which was sponsored by The Institute for the Study of Animal Problems, 2100 L Street, N.W., Washington, D.C. in connection with The Myrin Institute for Adult Education, 521 Park Avenue, New York, N.Y. 10021.

Comparative Effects Of Two Avoidance Paradigms Upon Ethanol Self-Selection, Richard O. Shellenberger Ii

Masters Theses

Twelve adult male rats were given free access to a two bottle free-selection of tap water or a 10% ethanol/tap water solution in the home cage for a period of 140 consecutive days with the alcohol consumption data in the form of mg absolute ETOH/g subject weight collected daily. This study incorporated three stages. Phase I was a 40 day period of alcohol acclimation with alcohol consumption during the second 20 days constituting the baseline consumption rate. Mean baseline alcohol consumption was used to block subjects into three groups. The second phase of the study consisted of an 80 day …

Alternatives To Laboratory Animals: Definition And Discussion, Andrew N. Rowan

The Institute for the Study of Animal Problems [ISAP]

The origins of the concept of "alternatives" to the use of animals in research may be traced back to the 1800's and the furore about using live animals in surgical and other experiments. Some of the animal protection societies in England were prepared to accept animal experimentation provided it was performed under anesthesia. Even Dr. Marshall Hall, who championed the spread of experimental medicine in 19th century England, considered it necessary to control and prevent unwarranted, inept and cruel experimentation (French, 1975). The concept of alternatives has developed in the 20th century to encompass not only the reduction (prevention) of …

Euthanasia Of Dogs And Cats: An Analysis Of Experience And Current Knowledge With Recommendations For Research, T. Carding, M. W. Fox

eBooks

1978 Special Report prepared by the Institute for the Study of Animal Problems

State-Dependent Learning As A Function Of The Temporal Relationship Between Noncontingent Footshock And Electroconvulsive Shock, T. Scott Shutt

All Master's Theses

Rats were given a noncontingent footshock followed at various intervals by electroconvulsive shock. Twentyfour hours later they were trained on a non-shock passive avoidance task and tested for retention 72 hours later. When the interval between NCFS and ECS was short the animals showed an amnesia which reduced as the interval was lengthened. An interval of .5 seconds produced the most pronounced amnesia and intervals greater than 10 seconds produced virtually no amnesia. The results were consistent with a state dependent retrieval failure hypothesis.

The Cathartic Effects Of Aggressive Responses Directed Toward An Inanimate Object, Timothy William Creston

All Master's Theses

This study was intended to test the catharsis of aggression hypothesis which in part holds that aggressive responses directed towards an inanimate object will have a tension reducing effect and result in a lowering of residual hostility.

Sub-Aversive Response Contingent Foot Shock As A Positive Reinforcer, Robert Lea Fulwiler

All Master's Theses

Forty-eight rats were divided into 8 groups; four were maintained under normal conditions and the other four under sensory deprivation and tested at o, 3, 6, and 9 days after condition institution. The response was placing the head through a hole in the operant chamber and the stimulus (0, 1.2, 4, or 12 Vac) was contingent upon the response. Analysis ot variance disclosed significant differences (p<.01) between the deprived and the non-deprived groups at days 6 and 9; and a significant interaction between deprivation condition and time of test. No differences were shown between the stimulus intensities indicating that the stimulus did not have a reinforcing effect.

The Effects Of Cs Habituation And Duration Of The Directional Modification Of The Cardiac Response In The Guinea Pig (Cavia Procellus), Ray Charles Larson

All Master's Theses

The present experiment examined the effects of CS habituation and two different levels of CS duration (60 versus 6 sec) on the directional modification of the conditioned cardiac response in the guinea pig. The results indicated that the only reaction to the CS, regardless of prior habituation or CS duration, was a decelerative conditioned HR response. However, habituation to a CS prior to classical aversive conditioning was found to attenuate the magnitude of the bradycardia CR that developed. The bradycardia CR was discussed in terms of being a cardiac component of the orienting response.

Protection For Animals In Biomedical Research, F. L. Thomsen

Laboratory Experiments Collection

Our conclusion from all of this work and study is that not just a small part, but that most of the suffering undergone by laboratory animals in "unnecessary" under the terms of the pain provisions of the Rogers-Javits bill. Granted, it will take some time and effort to bring about the necessary interpretations of these provisions. The Act, when passed, offers us the medium through which to obtain such interpretations.

This unnecessary suffering results mostly from the indifference, and from the inertia and the lack of proper scientific training and technical knowledge, of many of those conducting laboratory animal experiments …

How Can We Best Help Laboratory Animals Now?, Oliver Evans

Laws and Legislation Collection

No abstract provided.