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Articles 211 - 240 of 291

Full-Text Articles in Plant Pathology

Results Of The Tenth International Winter Wheat Performance Nursery Grown In 1978, S. L. Kuhr, V. A. Johnson, P. J. Mattern, K. D. Wilhelmi, J. W. Schmidt Jul 1981

Results Of The Tenth International Winter Wheat Performance Nursery Grown In 1978, S. L. Kuhr, V. A. Johnson, P. J. Mattern, K. D. Wilhelmi, J. W. Schmidt

Nebraska Agricultural Experiment Station: Historical Research Bulletins

This is the tenth report of results from an International Winter Wheat Performance Nursery (IWWPN) organized in 1968 by the Nebraska Agricultural Experiment Station in cooperation with the Science and Education Administration (SEA), U.S. Department of Agriculture, under contract number AID/ta-C-1093 with the U.S. International Development Corporation, Agency for International Development. The Nursery was designed to (1) test the adaptation and stability of winter wheat cultivars in a range of latitudes, daylengths, fertility conditions, water management regimes, and disease complexes; (2) identify superior winter cultivars to serve as recipient genotypes for high protein and high lysine genes: (3) test the …


Proceedings Of The 8th Annual Meeting, Southern Soybean Disease Workers (March 11-12, 1981, Memphis, Tennessee): Soybeans, The Crop Of The Future Jan 1981

Proceedings Of The 8th Annual Meeting, Southern Soybean Disease Workers (March 11-12, 1981, Memphis, Tennessee): Soybeans, The Crop Of The Future

Southern Soybean Disease Workers: Conference Proceedings

General Session

Presidential Address - Glen Whitney

The Influence of Plant Diseases on American Agriculture - Wiley Garrett

Integrated Pest Management: A National Prospective - B. Blair

Development in Brazil, the Future World Supplier of Food: Industry Overview - Ray Smith

Soybean Disease Loss Estimate - R. V. Sturgeon

Soybeans, Seed, Seedling, and Soil-Borne Disease, James Kantzes presiding

Standardized Seed Treatment Research Report - M. C. McDaniel

Soybean Seedling Disease Control and Plant Populations - Norman Horn

Metalaxyl: A New Seed Dressing and Soil Treatment Fungicide - H. V. Morton and D. Houseworth

Soybean Seed Treatment: U. S. Status …


Results Of The Second High Protein-High Lysine Wheat Observation Nursery Grown In 1976, S. L. Kuhr, K. D. Wilhelmi, V. A. Johnson, P. J. Mattern Jan 1980

Results Of The Second High Protein-High Lysine Wheat Observation Nursery Grown In 1976, S. L. Kuhr, K. D. Wilhelmi, V. A. Johnson, P. J. Mattern

Nebraska Agricultural Experiment Station: Historical Research Bulletins

This is the second report of results from a high protein-high lysine (HP-HL) observation nursery organized in 1974 by the Nebraska Agricultural Experiment Station and the Science and Education Administration, U. S. Department of Agriculture, under a contract with the Agency for International Development, U. S. Department of State. Primary objectives of this nursery are to: (1) Systematically provide breeders and cooperators with superior genetic germplasm for elevated levels of protein and/or lysine. (2) Test the degree of expression of the high protein and high lysine traits in a diverse array of environments. Funding from USAID has permitted the Nebraska …


Proceedings Of The 7th Annual Meeting, Southern Soybean Disease Workers (April 2-3, 1980, Fort Walton Beach, Florida) Jan 1980

Proceedings Of The 7th Annual Meeting, Southern Soybean Disease Workers (April 2-3, 1980, Fort Walton Beach, Florida)

Southern Soybean Disease Workers: Conference Proceedings

Contents

Schedule, Committees, Officers

History of the Southern Soybean Disease Workers, Glen Whitney

Presidential Address, H. Ray Smith

Global Agriculture Year 2000: A Strategic Analysis, Stuart Stearns

Attorneys Got Us Into This Mess, Attorneys Must Get Us Out, John Donley

Soybeans as a Protein Source, Kenneth Lepley

Soybeans in Human Nutrition, Ruth Patrick

Review of Plant Parasitic Nematode Problems on Soybeans, John Fulkerson

Efficacy of Nematicides for Nematode Control, Charles Baldwin

Breeding for Nematode Resistance, C. E. Caviness and R. D. Riggs

Effects of Fertility on Efficacy of Nematicides for Control of the Soybean Cyst Nematode, Al Chambers

Mississippi's Approach …


Results Of The Ninth International Winter Wheat Performance Nursery Grown In 1977, S. L. Kuhr, K. D. Wilhelmi, V. A. Johnson, P. J. Mattern, J. W. Schmidt Sep 1979

Results Of The Ninth International Winter Wheat Performance Nursery Grown In 1977, S. L. Kuhr, K. D. Wilhelmi, V. A. Johnson, P. J. Mattern, J. W. Schmidt

Nebraska Agricultural Experiment Station: Historical Research Bulletins

This is the ninth report of results from an International Winter Wheat Performance Nursery (IWWPN) organized in 1968 by the Nebraska Agricultural Experiment Station and the Science and Education Administration (SEA), U.S. Department of Agriculture, under a contract with the Agency for International Development, U.S. Department of State. The Nursery was designed to (1) test the adaptation and stability of winter wheat cultivars in a range of latitudes, daylengths, fertility conditions, water management regimes, and disease complexes; (2) identify superior winter cultivars to serve as recipient genotypes for high protein and high lysine genes, (3) test the degree of expression …


Proceedings Of The 6th Annual Meeting, Southern Soybean Disease Workers (March 13-15, 1979, Hot Springs, Arkansas): Healthy Beans, A Key To Profit Jan 1979

Proceedings Of The 6th Annual Meeting, Southern Soybean Disease Workers (March 13-15, 1979, Hot Springs, Arkansas): Healthy Beans, A Key To Profit

Southern Soybean Disease Workers: Conference Proceedings

Contents

Schedule, Committees, Officers

The Gold That Grows, John Stephens

IPM Program, Joe Good

The Role of the Ag Consultant - Dick Jensen

Seed Quality, Ron Hager

Nematode-Economic Threshold, Don Schmitt

Problems of Marketing Foliar Fungicides, Gordon Elliott and Nic Thomas

Results of Point System in Determining Application Time, Billy Moore

Disease Loss Report, R. V. Sturgeon

Seed Treatment Report, M. C. McDaniel

SSDW Financial Status Report, Sid Stephens

Update of FIFRA and RPAR, Curtis L. Mason

Needs and Effects of a Foliar Fungicide - B. C. Smale

The Effect of Bean Pod Mottle, Soybean Mosaic and Bean Yellow Mosaic …


Results Of The Eighth International Winter Wheat Performance Nursery Grown In 1976, K. D. Wilhelmi, S. L. Kuhr, V. A. Johnson, P. J. Mattern, J. W. Schmidt Jul 1978

Results Of The Eighth International Winter Wheat Performance Nursery Grown In 1976, K. D. Wilhelmi, S. L. Kuhr, V. A. Johnson, P. J. Mattern, J. W. Schmidt

Nebraska Agricultural Experiment Station: Historical Research Bulletins

This is the eighth report of results from an International Winter Wheat Performance Nursery (IWWPN) organized in 1968 by the Nebraska Agricultural Experiment Station and the Science and Education Administration (SEA), U.S. Department of Agriculture, under a contract with the Agency for International Development, U.S. Department of State. The Nursery was designed to (1) test the adaptation and stability of winter wheat cultivars in a range of latitudes, daylengths, fertility conditions, water management regimes, and disease complexes; (2) identify superior winter cultivars to serve as recipient genotypes for high protein and high lysine genes, (3) test the degree of expression …


Results Of The First High Protein-High Lysine Wheat Observation Nursery Grown In 1975, K. D. Wilhelmi, S. L. Kuhr, V. A. Johnson, P. J. Mattern Apr 1978

Results Of The First High Protein-High Lysine Wheat Observation Nursery Grown In 1975, K. D. Wilhelmi, S. L. Kuhr, V. A. Johnson, P. J. Mattern

Nebraska Agricultural Experiment Station: Historical Research Bulletins

This is the first report of results from a high protein-high lysine observation (HP-HL) nursery organized in 1974 by the Nebraska Agricultural Experiment Station and the Agricultural Research Service, U.S. Department of Agriculture, under a contract with the Agency for International Development, U.S. Department of State. Primary objectives of this nursery are to: (1) Systematically provide breeders and cooperators with superior genetic germplasm for elevated levels of protein and/or lysine. (2) Test the degree of expression of the high protein and high lysine traits in a diverse array of environments.


Proceedings Of The 5th Annual Meeting, Southern Soybean Disease Workers (March 21-23, 1978, Fort Walton Beach, Florida): 3 P'S In A Pod - Policies, Protection, Production Jan 1978

Proceedings Of The 5th Annual Meeting, Southern Soybean Disease Workers (March 21-23, 1978, Fort Walton Beach, Florida): 3 P'S In A Pod - Policies, Protection, Production

Southern Soybean Disease Workers: Conference Proceedings

Contents

Farm Policies, Weldon Barton (Assistant US Secretary of Agriculture)

World Soybean Problems, Glen Whitney, Dick Ford, and Frank Ray

Interrelation of Governmental Agencies with Industry, University, and Soybean Producers
EPA: Relationship and Responsibility to Agriculture and the Public, Nathan Chandler
EPA: Problems and Requirements of Registration, Herb Harrison
State: Pesticide Impact Program, Charles Smith
Industry: View on Benefit and Risk of the Pesticide Business, Charles Gilbert
University: Role of Land Grant University in Pesticide Development, James Martin
Producer: What's Needed, "Profit or Perish," Peter Myers

DBCP Status Report and Other Nematicides
Shell Chemical, Max Sckerl
Dow Chemical, Walter Miller …


Results Of The Seventh International Winter Wheat Performance Nursery Grown In 1975, K. D. Wilhelmi, S. L. Kuhr, V. A. Johnson, P. J. Mattern, J. W. Schmidt Oct 1977

Results Of The Seventh International Winter Wheat Performance Nursery Grown In 1975, K. D. Wilhelmi, S. L. Kuhr, V. A. Johnson, P. J. Mattern, J. W. Schmidt

Nebraska Agricultural Experiment Station: Historical Research Bulletins

This is the seventh report of results from an International Winter Wheat Performance Nursery (IWWPN) organized in 1968 by the Nebraska Agricultural Experiment Station and the Agricultural Research Service, U.S. Department of Agriculture, under a contract with the Agency for International Development, U.S. Department of State. The Nursery was designed to (1) test the adaptation of winter wheat cultivars in a range of latitudes, daylengths, fertility conditions, water management regimes, and disease complexes; (2) identify superior winter cultivars to serve as recipient genotypes for high protein and high lysine genes, and (3) test the degree of expression and stability of …


Results Of The Sixth International Winter Wheat Performance Nursery Grown In 1974, K. D. Wilhelmi, S. L. Kuhr, V. A. Johnson, P. J. Mattern, J. W. Schmidt Dec 1976

Results Of The Sixth International Winter Wheat Performance Nursery Grown In 1974, K. D. Wilhelmi, S. L. Kuhr, V. A. Johnson, P. J. Mattern, J. W. Schmidt

Nebraska Agricultural Experiment Station: Historical Research Bulletins

This is the sixth report of results from an International Winter Wheat Performance Nursery (IWWPN) organized in 1968 by the Nebraska Agricultural Experiment Station and the Agricultural Research Service, U. S. Department of Agriculture, under a contract with the Agency for International Development, U.S. Department of State. The Nursery was designed to (1) test the adaptation of winter wheat cultivars in a range of latitudes, daylengths, fertility conditions, water management, and disease complexes; (2) identify superior winter cultivars to serve as recipient genotypes for high protein and high lysine genes, and (3) test the degree of expression and stability of …


Results Of The Fifth International Winter Wheat Performance Nursery Grown In 1973, J. E. Stroike, K. D. Wilhelmi, V. A. Johnson, J. W. Schmidt, P. J. Mattern Apr 1976

Results Of The Fifth International Winter Wheat Performance Nursery Grown In 1973, J. E. Stroike, K. D. Wilhelmi, V. A. Johnson, J. W. Schmidt, P. J. Mattern

Nebraska Agricultural Experiment Station: Historical Research Bulletins

This is the fifth report of results from an International Winter Wheat Performance Nursery (IWWPN) organized in 1968 by the Nebraska Agricultural Experiment Station and the Agricultural Research Service, U. S. Department of Agriculture, under a contract with the Agency for International Development, U. S. Department of State. The Nursery was designed to (1) test the adaptation of winter wheat cultivars in a range of latitudes, daylengths, fertility conditions, water management, and disease complexes; (2) identify superior winter cultivars to serve as recipient genotypes for high protein and high lysine genes, and (3) test the degree of expression and stability …


Bulletin No 3863 - Plants Which Cause Kimberley Horse Disease, A. L. Payne Apr 1976

Bulletin No 3863 - Plants Which Cause Kimberley Horse Disease, A. L. Payne

Bulletins - 3000 - 3999

Crotalaria crispata and Crotalaria retusa (Rattlepod), two plants responsible for Kimberley horse disease*, are, unfortunately, fairly widespread throughout the Kimberleys. Both species are apparently toxic in all stages of growth.

This bulletin is to assist pastoralists to:-

• Identify the two plants;

• Recognise the type of country and conditions under which they grow; and

• Locate horse paddocks on country where the plants are least likely to occur.


Leaf Freckles And Wilt Of Corn Incited By Corynebacterium Nebraskense Schuster, Hoff, Mandel, Lazar, 1972, M. L. Schuster May 1975

Leaf Freckles And Wilt Of Corn Incited By Corynebacterium Nebraskense Schuster, Hoff, Mandel, Lazar, 1972, M. L. Schuster

Nebraska Agricultural Experiment Station: Historical Research Bulletins

The new bacterial disease Leaf Freckles and Wilt (LFW) of corn (Zea mays L.) was first observed in 1969 on two farms in southcentral Nebraska. Since then it has spread to other areas in the state. LFW is a serious disease on farms in six Nebraska counties (Clay, Custer, Dawson, Furnas, Hall and Phelps) and has been found in isolated cases in at least 28 other counties. In 1971 LFW was found in a seedcorn field in western Iowa, in 1973 in two Kansas counties, and in 1974 in South Dakota and Colorado. Because of its explosive nature, several …


Survival Factors Of Plant Pathogenic Bacteria, M. L. Schuster, D. P. Coyne Feb 1975

Survival Factors Of Plant Pathogenic Bacteria, M. L. Schuster, D. P. Coyne

Nebraska Agricultural Experiment Station: Historical Research Bulletins

The research works discussed in this review were selected to provide a cross section of the phenomenon of survival of plant pathogenic bacteria.


Results Of The Fourth International Winter Wheat Performance Nursery, J. E. Stroike, V. A. Johnson, J. W. Schmidt, P. J. Mattern, K. D. Wilhelmi Oct 1974

Results Of The Fourth International Winter Wheat Performance Nursery, J. E. Stroike, V. A. Johnson, J. W. Schmidt, P. J. Mattern, K. D. Wilhelmi

Nebraska Agricultural Experiment Station: Historical Research Bulletins

The Fourth International Winter Wheat Performance Nursery was grown in 1972 at 44 sites in 27 countries. Data were reported from 40 sites. The 30 cultivars grown in the nursery included 15 new entries. Twenty-nine cultivars were winter wheats; one was a spring wheat. Data are reported on grain yield, test weight, plant maturity, plant height, lodging, shattering, winter survival, 1000 kernel weight, frost damage, plant diseases, grain protein and lysine content. Two-year mean data summaries also are reported. Supplemental nursery management information is reported for each nursery site.


Results Of The Third International Winter Wheat Performance Nursery, J. E. Stroike, V. A. Johnson, J. W. Schmidt, P. J. Mattern, K. D. Wilhelmi Nov 1973

Results Of The Third International Winter Wheat Performance Nursery, J. E. Stroike, V. A. Johnson, J. W. Schmidt, P. J. Mattern, K. D. Wilhelmi

Nebraska Agricultural Experiment Station: Historical Research Bulletins

This is the third report of results from an International Winter Wheat Performance Nursery (IWWPN) organized in 1968 by the Nebraska Agricultural Experiment Station and the Agricultural Research Service, U.S. Department of Agriculture, under a contract with the Agency for International Development, U.S. Department of State. The nursery was designed to (1) test the adaptation of winter wheat varieties in a range of latitudes, daylengths, fertility conditions, water management, and disease complexes; (2) identify superior winter varieties to serve as recipient genotypes for high protein and high lysine genes, and (3) test the degree of expression and stability of the …


Results Of The Second International Winter Wheat Performance Nursery, J. E. Stroike, V. A. Johnson, J. W. Schmidt, P. J. Mattern Sep 1972

Results Of The Second International Winter Wheat Performance Nursery, J. E. Stroike, V. A. Johnson, J. W. Schmidt, P. J. Mattern

Nebraska Agricultural Experiment Station: Historical Research Bulletins

The Second International Winter Wheat Performance Nursery was grown in 1970 at 38 sites in 23 countries. Four of the sites were in the southern hemisphere. Data were reported from 36 sites. The same 30 varieties evaluated in the First International Winter Wheat Performance Nursery were grown in this Second International Winter Wheat Performance Nursery. Twenty-eight varieties were winter wheats; two were spring wheats. Data on grain yield, test weight, maturity, plant height, lodging, shattering, winter survival, diseases, grain protein content and lysine content for 1970 are reported. Two-year mean data summaries also are reported.


Date Of Planting Studies Of Winter Wheat And Winter Barley In Relation To Root And Crown Rot Grain Yields And Quality, C. R. Fenster, M. G. Boosalis, J. L. Weihing Apr 1972

Date Of Planting Studies Of Winter Wheat And Winter Barley In Relation To Root And Crown Rot Grain Yields And Quality, C. R. Fenster, M. G. Boosalis, J. L. Weihing

Nebraska Agricultural Experiment Station: Historical Research Bulletins

This study was undertaken to determine the nature of root and crown rot of wheat and to ascertain the proper time to plant winter wheat so as to conserve moisture, minimize root and crown rot and thereby maximize yield. Studies conducted for 15 years at several locations in western Nebraska reveal that planting date is a significant factor for higher yields, particularly in certain years.


Bulletin No 3861 - Kimberley Research Station - Progress Report 1972, J. R. Mcalpine, R. H. Gunn, P. Jakobsen, R. Wetselaar, J. J. Basinski, N. J. Thomson, A. G. L. Wilson, D. H. Mackenzie, A. J. Millington, D. F. Beech, P. C. Owen, B. G. Williams, C. G. Blunt, A. Mcr Holm Jan 1972

Bulletin No 3861 - Kimberley Research Station - Progress Report 1972, J. R. Mcalpine, R. H. Gunn, P. Jakobsen, R. Wetselaar, J. J. Basinski, N. J. Thomson, A. G. L. Wilson, D. H. Mackenzie, A. J. Millington, D. F. Beech, P. C. Owen, B. G. Williams, C. G. Blunt, A. Mcr Holm

Bulletins - 3000 - 3999

The systematic investigations of the potential of the Ord area for irrigated farming began during the Second World War when the possibilities of damming the river were first examined, initial soil survey was carried out, and agricultural experiments started. The Kimberley Research Station was established on its present site in 1945. A year later the State and Commonwealth Governments agreed to finance and operate the Station jointly, with CSIRO and the Western Australian Department of Agriculture being responsible for research.

The construction of the main dam designed to store 5,675 million m" ( 4.6 million acre feet) was completed in …


Results Of The First International Winter Wheat Performance Nursery, J. E. Stroike, V. A. Johnson, J. W. Schmidt, P. J. Mattern Jul 1971

Results Of The First International Winter Wheat Performance Nursery, J. E. Stroike, V. A. Johnson, J. W. Schmidt, P. J. Mattern

Nebraska Agricultural Experiment Station: Historical Research Bulletins

The International Winter Wheat Performance Nursery was organized by the Nebraska Agricultural Experiment Station and the Agricultural Research Service, U.S. Department of Agriculture, under a contract with the Agency for International Development, U.S. Department of State. There has been informal cooperation with the Food and Agriculture Organization, United Nations, and the International Maize and Wheat Improvement Center (CIMMYT), Mexico, D. F. Specific objectives of the nursery are to: (1) Test the adaptation of winter wheat varieties under a range of latitudes, daylengths, fertility conditions, water management and disease complexes (2) Identify superior winter varieties to serve as recipient genotypes for …


Bulletin No 3768 - Submitting Plants For Disease Identification, M D. Marcley Feb 1971

Bulletin No 3768 - Submitting Plants For Disease Identification, M D. Marcley

Bulletins - 3000 - 3999

THERE are several important points to remember when submitting plant material for disease identification by the Department of Agriculture's Plant Pathology Branch.

Firstly it is very important to collect a suitable sample because it is very difficult to determine the cause of a plant disease by looking at a completely dead plant. The sample should include the entire plant (before it is completely dead) including roots and soil. Then all the effects of the disease can be seen. For example leaf yellowing, dead areas of the stem, collar rot, root rot, eelworm damage, and disease of the water and food …


Field Peas : A Crop For The Cereal Growing Areas?, M L. Poole, H. M. Fisher Jan 1971

Field Peas : A Crop For The Cereal Growing Areas?, M L. Poole, H. M. Fisher

Journal of the Department of Agriculture, Western Australia, Series 4

No abstract provided.


Copper Requirements For The South-Eastern Wheatbelt, D J. Gilbey, K. D. Greathead, J. W. Gartrell Jan 1970

Copper Requirements For The South-Eastern Wheatbelt, D J. Gilbey, K. D. Greathead, J. W. Gartrell

Journal of the Department of Agriculture, Western Australia, Series 4

FARM experience and the results of five years intensive research have shown copper deficiency to be widespread in the south-eastern wheatbelt.

On many areas of the south-eastern wheatbelt, copper deficiency is likely to restrict wheat yields.


Submitting Plants For Disease Identification, M D. Marcley Jan 1970

Submitting Plants For Disease Identification, M D. Marcley

Journal of the Department of Agriculture, Western Australia, Series 4

THERE are several important points to remember when submitting plant material for disease identification by the Department of Agriculture's Plant Pathology Branch.


Growing Barley For Grain In Western Australia : Barley Quality, J A. Parish Jan 1970

Growing Barley For Grain In Western Australia : Barley Quality, J A. Parish

Journal of the Department of Agriculture, Western Australia, Series 4

Plumpness and absence of pinched grain are desirable for both malting and feed barley.

This is a brief discussion of various Quality standards in barley and how they may not be met.


Controll Of Eelworm Diseases Of Bananas In Western Australia : A Review, O M. Goss, M. G. Hawson Jan 1969

Controll Of Eelworm Diseases Of Bananas In Western Australia : A Review, O M. Goss, M. G. Hawson

Journal of the Department of Agriculture, Western Australia, Series 4

During the 1950's, a decline in bananas in plantations in Carnarvon, caused by heavy infestations of eelworms, prompted investigations into eelworm control.

The work was started in 1955. The results and recommendations based on experiments have been published in Department of Agriculture Bulletin 3532.


Linseed : An Alternative Crop For The South Coast, R J. Doyle, R. J. Guyton Jan 1969

Linseed : An Alternative Crop For The South Coast, R J. Doyle, R. J. Guyton

Journal of the Department of Agriculture, Western Australia, Series 4

IN the over-17 inch rainfall zone of the south coast region of Western Australia animal production is the main farm enterprise.

Although farmers in the main cereal growing regions of W.A. crop about one-third of their cleared land each year, farmers in the south have been reluctant to crop more than about 12 per cent, of their cleared area.


Why Australia Needs Plant Quarantine, A T. Gulvin Jan 1968

Why Australia Needs Plant Quarantine, A T. Gulvin

Journal of the Department of Agriculture, Western Australia, Series 4

LATE blight of potatoes in 1830, powdery mildew of grapes in 1847, phylloxera in 1861, downy mildew in 1875, and black rot in 1838 . . . It was this grim list of plant disease epidemics in Europe that forced Governments to protect plants by quarantine.


Northern Corn Leaf Blight (Helminthosporium Turcicum Pass.) On Susceptible And Resistant Corn, Saffet Baydar Jan 1968

Northern Corn Leaf Blight (Helminthosporium Turcicum Pass.) On Susceptible And Resistant Corn, Saffet Baydar

Open Access Master's Theses (through 2010)

The objectives of the research reported herein were to (1) become familiar with the technique of inoculating corn with Helminthosporium turcicum, (2) become familiar with a technique of evaluating the susceptibility of corn lines to H. turcicum, (3) become familiar with plant reaction and organism development in the various types of corn and (4) evaluate Turkish corn susceptibility in relation to various types of germ plasm in American corn lines in order to assist in combating the serious disease of Northern corn left blight in Turkey.

Comparative reactions of 10 Turkish, 5 multigenic resistant, 2 heterozygous monogenic …