Physiology Commons^™

Effects Of Voluntary Exercise On Pressure-Induced Natriuresis In Hypertensive Female And Male Rats, Keshari Sudasinghe

All Graduate Theses, Dissertations, and Other Capstone Projects

Hypertension (HT) is one of the major diseases associated with the circulatory system and remains a public health problem with a high rate of prevalence in the adult population in the USA. The pressure natriuresis mechanism which is Na+ excretion in respond to rise in blood pressure acts as a long-term regulator of arterial blood pressure. Recent studies have demonstrated that impairment of this long-term pressure natriuresis mechanism is involved in hypertension (HT) and many other renal disorders. Exercise is a nonpharmacological treatment to help control HT, and exercise has a beneficial effect on vascular health, endothelial functions, arterial stiffness, …

Vulnerable And Resilient Phenotypes In A Mouse Model Of Anorexia Nervosa, Jeff A. Beeler, Devry Mourra, Roseanna M. Zanca, Abigail Kalmbach, Celia Gellman, Benjamin Y. Klein, Rebecca Ravenelle, Peter Serrano, Holly Moore, Stephen Rayport, Susana Mingote, Nesha Burghard

Advanced Science Research Center

Background

Increased physical activity is a common feature of anorexia nervosa (AN). Although high activity levels are associated with greater risk of developing AN, particularly when combined with dieting, most individuals who diet and exercise maintain a healthy body weight. It is unclear why some individuals develop AN while most do not. A rodent model of resilience and vulnerability to AN would be valuable to research. Dopamine, which is believed to play a crucial role in AN, regulates both reward and activity and may modulate vulnerability.

Methods

Adolescent and young adult female C57BL/6N mice were tested in the activity-based anorexia …

Energy Expenditure And Muscular Recruitment Patterns Of Riding A Novel Electrically Powered Skateboard, Anthony J. Robinson, Robert P. Carter, Jonathan D. Browne, Jonathan Hu, Michael T. Arnold, Jaxon T. Baum, Eric V. Neufeld, Brett A. Dolezal

International Journal of Exercise Science

International Journal of Exercise Science 13(4): 1783-1793, 2020. Analysis of metabolic gas exchange and muscular output measures have enabled researchers to index activity intensity and energy expenditure for a myriad of exercises. However, there is no current research that investigates the physiological demands of riding electrically powered skateboards. The aim of this study was to measure the energetic cost and muscular trends of riding a novel electrically powered skateboard engineered to emulate snowboarding on dry-land. While riding the skateboard, eight participants (aged 21-37 years, 1 female) donned a portable breath-by-breath gas analyzer to measure energy expenditure (mean = 12.5, …

No Change In Executive Function Or Stress Hormones Following A Bout Of Moderate Treadmill Exercise In Preadolescent Children, Brian T. Ebisuzaki, Nicholas D. Riemen, Kory M. Bettencourt, Lupita M. Gonzalez, Kelly A. Bennion, Cory J. Greever

International Journal of Exercise Science

International Journal of Exercise Science 13(5): 1650-1666, 2020. Several studies suggest that acute bouts of exercise improve executive function in preadolescent children. However, the mechanisms underlying these effects are not completely understood. Specifically, no studies have examined the relationship between the stress hormone response to exercise and improvements in executive function in preadolescent children. The purpose of this study was to examine the effects of a bout of moderate intensity exercise versus rest on working memory (List Sorting Working Memory Task) and selective inhibition/attention (Eriksen flanker task) in preadolescent children, as well as to investigate whether changes in stress hormones …

Physiological Responses To Counterweighted Single-Leg Cycling In Older Males, Phil Lascola, C. Eric Heidorn, Brandon Pollock, Keith Burns, John Mcdaniel

International Journal of Exercise Science

International Journal of Exercise Science 13(2): 1487-1500, 2020. Single-leg cycling (SLC) allows for a greater muscle specific exercise capacity and therefore provides a greater stimulus for metabolic and vascular adaptations compared to double-leg cycling (DLC). The purpose of this investigation was to compare the cardiovascular, peripheral, and metabolic responses of counterweighted (10kg) SLC to DLC in a healthy older male population. Eleven males (56-86 years) performed two cycling modalities consisting of DLC and SLC. For each modality, participants performed 4-minute cycling trials (60rpm) at three work rates (25, 50, 75W). Repeated measures ANOVAs and paired samples T-test (α=0.05) were used …

Rats Genetically Selected For High Aerobic Exercise Capacity Have Elevated Plasma Bilirubin By Upregulation Of Hepatic Biliverdin Reductase-A (Bvra) And Suppression Of Ugt1a1, Terry D. Hinds Jr., Justin F. Creeden, Darren M. Gordon, Adam C. Spegele, Steven L. Britton, Lauren G. Koch, David E. Stec

Pharmacology and Nutritional Sciences Faculty Publications

Exercise in humans and animals increases plasma bilirubin levels, but the mechanism by which this occurs is unknown. In the present study, we utilized rats genetically selected for high capacity running (HCR) and low capacity running (LCR) to determine pathways in the liver that aerobic exercise modifies to control plasma bilirubin. The HCR rats, compared to the LCR, exhibited significantly higher levels of plasma bilirubin and the hepatic enzyme that produces it, biliverdin reductase-A (BVRA). The HCR also had reduced expression of the glucuronyl hepatic enzyme UGT1A1, which lowers plasma bilirubin. Recently, bilirubin has been shown to activate the peroxisome …

Cross-Validation Of Ratings Of Perceived Exertion Derived From Heart Rate Target Ranges Recommended For Pregnant Women, Danilo F. Da Silva, Shuhiba Mohammad, Kelly Ann Hutchinson, Kristi B. Adamo

International Journal of Exercise Science

International Journal of Exercise Science 13(3): 1340-1351, 2020. Currently, there are no established evidence-based rating of perceived exertion (RPE) targets for physical activity (PA) in pregnant women. Yet, a set of target heart rate (HR) ranges have been recommended. Using the Borg Scale, we aimed to determine and validate the RPE target ranges for different PA intensities derived from the recommended HR ranges in the 2019 Canadian Guideline for PA throughout pregnancy. We assessed 13 pregnant women (age: 31.2 ± 3.5 years; gestational age: 20.5 ± 5.0 weeks) using the following three phases: 1) the incremental submaximal walking test to …

Not All Hift Classes Are Created Equal: Evaluating Energy Expenditure And Relative Intensity Of A High-Intensity Functional Training Regimen, Jonathan D. Browne, Robert Carter, Anthony Robinson, Brigette Waldrup, Geoffrey Zhang, Erik Carrillo, Minhsang Dinh, Michael T. Arnold, Jonathan Hu, Eric V. Neufeld, Brett A. Dolezal

International Journal of Exercise Science

International Journal of Exercise Science 13(4): 1206-1216, 2020. The demand for efficient and effective exercises has grown in concert with increased attention to fitness as a determinant of overall health. While past studies have examined the benefits traditional conditioning exercises, there have been few investigations of high intensity functional training (HIFT). The aim of this study was to measure the energy expenditure and relative intensity from participation in a signature, 35-minute group-based HIFT regimen. During the HIFT session, 13 volunteers (aged 23-59 years, 6 females) donned a portable breath-by-breath gas analyzer and a heart rate monitor. Mean caloric expenditure (528 …

The Implementation Of Exercise For Chronic Kidney Disease And Dialysis Patients, Syed Ahmad Rizvi

Honors College Theses

While commonly known to be the organ that helps with urine production within the human body, the kidney plays one of the most crucial roles in maintaining homeostasis. When establishing all of the roles the kidney has on keeping humans healthy, there is the question of how does the body cope when a patient is diagnosed with kidney failure. One of the more common treatment options that allows the body to continue to function without a kidney is by beginning a patient on a form of dialysis. However, as with any treatment, there will always be a list of side …

Characterization Of Adult Heart Rate Responses During Recreational Skateboarding At Community Skateparks, Tyler Wiles, Daniel Kellogg, Heather Furr, Jeff A. Nessler, Sean C. Newcomer

International Journal of Exercise Science

International Journal of Exercise Science 13(2): 501-510, 2020. Youth participating in recreational skating at community skate parks attain exercise intensities and durations that are comparable with the CDC’s exercise recommendations for cardiovascular fitness for their age group. However, it is currently unclear if adults who skateboard in the same environment also achieve the recommended intensities and durations for cardiovascular fitness. Therefore, the purpose of this study was to test the hypothesis that skateboarding would elicit heart rates and durations consistent with the CDC’s recommendations for cardiovascular fitness in adults. Fifty-five subjects between ages 18-55 were recruited from six community skateparks …

Hypothesized Mechanisms Through Which Exercise May Attenuate Memory Interference, Lindsay K. Crawford, Hong Li, Liye Zou, Gao Xia Wei, Paul D. Loprinzi

Faculty and Student Publications

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. In this paper we introduce a mechanistic model through which exercise may enhance episodic memory, specifically via attenuating proactive and retroactive memory interference. We discuss the various types of memory, different stages of memory function, review the mechanisms behind forgetting, and the mechanistic role of exercise in facilitating pattern separation (to attenuate memory interference).

Measuring Physical Activity Using Triaxial Wrist Worn Polar Activity Trackers: A Systematic Review, André Henriksen, Jonas Johansson, Gunnar Hartvigsen, Sameline Grimsgaard, Laila A. Hopstock

International Journal of Exercise Science

International Journal of Exercise Science 13(4): 438-454, 2020. Collecting objective physical activity data from research participants are increasingly done using consumer-based activity trackers. Several validation studies of Polar devices are conducted to date, but no systematic review of the current level of accuracy for these devices exist. The aim of this study is therefore to investigate the accuracy of current wrist-worn Polar devices that equips a triaxial accelerometer to measure physical activity. We conducted a systematic review by searching six databases for validation studies on modern Polar activity trackers. Studies were grouped and examined by tested outcome, i.e. energy expenditure, …

Outdoor Time Is Not Associated With Metabolically Healthy Overweight And Obesity Phenotype In Canadian Children Aged 6-14 Years, Brittany Rioux, Neeru Gupta, Danielle Bouchard, James Dunbar, Martin Senechal

International Journal of Exercise Science

International Journal of Exercise Science 13(2): 383-394, 2020. A large proportion of children living with obesity have favorable cardiometabolic profiles despite their adiposity levels, who are referred to as metabolically healthy overweight or obese (MHO). However, the contribution of active outdoor time to the MHO phenotype is unknown. The purposeof this study was to investigate the association between outdoor time and moderate-to-vigorous physical activity (MVPA) with the MHO phenotype. A cross-sectional analysis of overweight/obese children aged 6-14 (n= 386) from the Canadian Health Measures Survey was performed. Outdoor time was self-reported using five questions in relation to …

Changes In Health Behaviors And Outcomes Following Graduation From Higher Education, Oliver W A Wilson, Peter J. Matthews, Michele Duffey, Zack Papalia, Melissa Bopp

International Journal of Exercise Science

International Journal of Exercise Science 13(5): 131-139, 2020. The purpose of this study was to examine changes in health behaviors and outcomes of higher education (college) students following graduation. Undergraduate students (n= 206) enrolled at a large, northeastern United States university in general education health and wellness courses were assessed pre and post-graduation. Participants self-reported their demographics, physical activity behaviors, dietary behaviors, sleep, and stress pre and post-graduation via an online survey. Paired sample t-tests examined changes health behaviors pre and post-graduation. Following graduation, fruit and vegetable consumption increased significantly, moderate physical activity declined significantly, and both vigorous …

Rate Of Perceived Exertion And Cardiorespiratory Fitness In Older Adults With And Without Alzheimer's Disease, Andrea Bevan, Eric Dennis Vidoni, Amber Watts

International Journal of Exercise Science

International Journal of Exercise Science 13(3): 18-35, 2020. Exercise has many benefits for physical and cognitive health in older adults, yet there are many barriers to exercise adherence in this population. Subjective perception of exercise difficulty, or rate of perceived exertion (RPE), may especially be a barrier to exercise in individuals with Alzheimer’s disease (AD), due to changes in initiation and motivation that accompany changes in cognition and brain function. RPE is the most commonly used measure of subjective effort in exercise research, yet the relationship between RPE and objective fitness is not fully understood in older adults. A better …

The Impact Of Exercise In Spaceflight And Microgravity Environments, William Bybee

Mahurin Honors College Capstone Experience/Thesis Projects

Since mankind’s first spaceflight, a significant barricade in reaching distant planets has been the damaging effects of microgravity upon the human body. Effects range from loss in bone mineral density and severe muscle atrophy to autoimmune disorders. The most effective countermeasure of these effects to date is exercise. Implementation of exercise in microgravity is not an easy task, so various specialized equipment must be utilized to effectively administer it. Even with this equipment, exercise as it is currently used does not entirely prevent body systems from undergoing detrimental changes. New modalities and implementations are currently being investigated that may significantly …

Causes And Potential Treatment For Altered Muscle Metaboreflex Control Of Ventricular Vascular Interactions In Heart Failure, Joseph Thomas Mannozzi

Wayne State University Dissertations

Muscle Metaboreflex Activation occurs as a result of metabolic accumulation within active skeletal muscle that stimulates type III and IV afferents. This reflex in healthy subjects causes increased ventricular contraction, tachycardia, enhanced central blood volume mobilization, and 2 mediated vasodilation as a means to increase mean arterial pressure and thereby improve perfusion pressure of active skeletal muscle. However, to date no study has evaluated the interaction between the observed changes in ventricular and vascular dynamics or how the reflex impacts contraction relaxation dynamics before and after induction of heart failure Furthermore, no study has evaluated the impact of chronic selective …

Demographics And Physical Activity Levels Of Esports Athletes At The University Of Akron, Madison Morgan, Patrick Barrett, Madeleine Stoll

Williams Honors College, Honors Research Projects

Esports is rapidly growing and gaining popularity, however there is a lack of research regarding physical activity levels of eSport athletes, especially those at the collegiate level. This study summarizes the current research and findings related to exercise, overall health, and video game performance. All varsity eSport athletes for The University of Akron varsity team were “participants” in this study. A survey tool was designed through Qualtrics (Qualtrics 2020© Provo, UT), an online survey instrument, to assess current physical activity levels, preferences and tolerance for exercise intensity, and perceptions about how physical activity affects gaming performance. This survey was distributed …

Effects Of A Strength Training Intervention And Quality Of Life: Case Study On A Sedentary Adult Female, Lucas Frazier

Williams Honors College, Honors Research Projects

The purpose of the project is to evaluate physiological and quality of life changes in a

sedentary, senior-aged (55 or older) female using a six-week strength training

intervention. This case study will instruct how to perform a push-pull-legs split

routine by going to the gym three times per week. Prior to the six week intervention,

both quantitative and qualitative variables will be collected to assess baseline data,

including the subject’s resting heart rate, resting blood pressure, grip strength, one-

repetition maximum on seven whole body exercises (dumbbell bicep curl, tricep

pushdown, barbell bench press, wide-grip lat pull-down, seated dumbbell press, …

Bone-Loading Physical Activity And Alcohol Intake But Not Bmi Affect Areal Bone Mineral Density In Young College-Aged Korean Women: A Cross-Sectional Study., Dong Jun Sung, Harshvardhan Singh, Seung-Bum Oh, Sojung Kim

College of Science & Mathematics Departmental Research

The purpose of this cross-sectional study was to determine the differences in areal bone mineral density (aBMD) based on alcohol consumption behaviors, bone-loading history as assessed by a bone-specific physical activity questionnaire (BPAQ), and the body mass index (BMI). College-aged female students (N = 112) were recruited from the universities in Seoul and Gyeonggi province, South Korea. The aBMD of the lumbar spine and non-dominant side of the proximal femur (total hip, TH; femoral neck, FN; femoral trochanter, FT) were measured using dual energy X-ray absorptiometry (DXA). Alcohol consumption was determined by the frequency and amount of alcohol intake during …

Examining The Relationship Of Exercise And Sleep In Students Across Multiple Academic Disciplines, Taylor Zewe

Honors Projects

Students in college learn the importance of balancing their academic studies with their sleep and exercise habits. The amount of sleep and exercise a student recieves has been examined in previous research studies. In these studies it was found that exercise had a postive affect on the amount of sleep received. However, there is little research on the affect academic discipline has on sleep habits and/or exercise habits of students in college. The purpose of this study is to examine the sleep and exercise habits among students in multiple academic majors at Bowling Green State University.

Effects Of A Game-Centered Health Promotion Program On Fall Risk, Health Knowledge, And Quality Of Life In Community-Dwelling Older Adults, Alyssa K. Dispennette, Mark A. Schafer, Matthew Shake, Brian Clark, Steven Vanover, Gretchen B. Macy, K. Jason Crandall

International Journal of Exercise Science

International Journal of Exercise Science 12(4): 1149-1160, 2019. Quality of life (QOL) is an important aspect of overall well-being in older adults and can be improved with increased physical activity. One in four older adults experiences a fall each year, making it necessary to focus public health interventions towards decreasing fall risk and improving QOL in older adults. The purpose of this study was to determine the effects of the health promotion program, Bingocize^®, on QOL and fall risk in community-dwelling older adults (n = 36; mean age 73.63 ± 6.97). Participants were clustered and randomly assigned …

Breathing Limited Air Situational Training Masks (Blastmask) Versus Self-Contained Breathing Apparatus (Scba) For Firefighters: A Pilot Study, Thomas Andre, Silvio Valladao, Shana Walsh, Derek Reisbeck

International Journal of Exercise Science

International Journal of Exercise Science 12(6): 941-949, 2019. Despite maintaining high levels of fitness, firefighters’ performance may be negatively impacted by the use of a Self-Contained Breathing Apparatus (SCBA), an essential piece of safety equipment worn during structural firefighting. Routine training with SCBAs can be cost-prohibitive and inefficient. The Breathing Limited Air Situational Training Mask (BlastMask) was developed as a training aid used to simulate the SCBA. The purpose of this study was to examine physiological and perceptual responses elicited by firefighters during steady state exercise when using the BlastMask compared to the SCBA. Current staff male firefighters (n …

The Impact Of Power Training On Balance And Visual Feedback Removal, Juliana Bouton

Senior Honors Theses

Because power training has been known to augment stability, the purpose of this study was to assess whether the removal of visual input affects lower limb muscle power production in young women who are resistance trained to the same degree it affects the untrained. This provided insight as far as the need for resistance training protocols in a largely untrained visually impaired population. To study this, fourteen college-aged female participants (18-23 years) performed a seated double-leg press on a leg sled machine, isolating power production of the lower limbs. After establishing baselines, which involved finding an average of power produced …

Comparison Of Steady State Exercise And Interval Training On Pitching Performance In Collegiate Baseball Players: A Pilot Study, Robert Rabena, Ryan Moran

International Journal of Exercise Science

International Journal of Exercise Science 12(6): 726-734, 2019. Traditionally, a baseball pitcher’s in-season conditioning between starts has consisted of steady state exercise. Little to no research exists on the effects of interval training on pitching performance. The purpose of this study was to examine the difference between steady state exercise (SSE) and interval training (IT) on exercise and pitching performance in collegiate baseball pitchers following an 11-week program. A total of 13 collegiate baseball pitchers were randomly assigned to either the SSE or IT group and tested pre- and post-season on a one-mile run, 30-m sprint, pitching velocity, walks plus …

Attitudes And Beliefs Regarding Pregnancy Physical Activity In A Non-Pregnant Population, Mallory R. Marshall, John K. Petrella

International Journal of Exercise Science

International Journal of Exercise Science 12(3): 636-645, 2019. The purpose of this study was to examine the attitudes and beliefs about pregnancy physical activity (PA) in non-pregnant individuals. We hypothesized that younger, more educated, females, those who had ever been pregnant (or partner had been pregnant, for males) and physically active individuals would view pregnancy PA more positively than older individuals, those with less education, males, those who had not ever been pregnant (partner had not been pregnant, for males), and those who are inactive, respectively. Participants were non-pregnant adults ages 20+ years who were recruited by word-of-mouth, social media, …

Effects Of Evidence-Based Materials And Access To Local Resources On Physical Activity During Pregnancy, Kolbi Edens

Masters Theses & Specialist Projects

Physical activity (PA) during pregnancy has been shown to be safe and effective for improving maternal and infant health; however, only 23% of pregnant women exercise in accordance with guidelines. PURPOSE: To determine if the distribution of evidence-based educational resources as well as access to community resources will increase PA levels as well as knowledge/beliefs about PA during pregnancy. METHODS: Participants (8-12 weeks) completed assessments concerning their activity levels, as well as knowledge/beliefs regarding PA, during pregnancy. Next, participants were randomly assigned to either an intervention (IG) or control group (CG). The IG received educational information regarding PA during pregnancy, …

Effect Of Fed State On Self-Selected Intensity And Affective Responses To Exercise Following Public Health Recommendations, Ryan Rhodewalt, Katelyn Largent, Blaque Saur, Todd Astorino Ph.D, Zachary Zenko, Matt Schubert

International Journal of Exercise Science

International Journal of Exercise Science 12(2): 602-613, 2019. Nutritional status has numerous effects on exercise metabolism and psychological responses. The effect of fed state on changes in affective valence; however, are unknown. Thus, the present study examined how fed state influenced self-selected exercise intensity, affective responses during exercise, and exercise enjoyment when exercise was completed following physical activity guidelines for public health. In a repeated-measures crossover design, 25 recreationally active men and women (age and BMI = 22.0 ± 2.0 yr and 24.3 ± 3.3 kg/m²) performed a single 30 min session of treadmill exercise at a Rating …

No Effect Of L-Arginine On Vascular Stiffness At Rest And During Reactive Hyperemia In Young Healthy Subjects, Andrew Wells, George Swanson, Thomas Fahey, Michael Smith

International Journal of Exercise Science

International Journal of Exercise Science 12(2): 556-566, 2019. The efficacy of L-arginine in augmenting blood flow via nitric oxide (NO) production is controversial, with several studies in the literature providing equivocal findings. The purpose of this study was to examine the effect of L-arginine supplementation on vascular stiffness at rest and during induced reactive hyperemia. Young healthy males (n = 15) were studied on two separate study days. On day one, a resting pulse wave velocity (PWV) was measured from the carotid and radial sites at rest and immediately following an induced reactive hyperemia (RH). On day two, subjects …

Effects Of Caffeine On Perceptually-Based Intensity Production During Outdoor Running, Kailee Neal, Matt Green, Eric O'Neal, Joyce Mcintosh, Alyssum Reno

International Journal of Exercise Science

ABSTRACT

International Journal of Exercise Science 12(5): 526-535, 2019. Caffeine (CAF) may enhance performance while altering estimated RPE. However, effects of caffeine on RPE production is not well understood. This study examined effects of CAF on velocity (VEL) selection during outdoor running when intensity was prescribed using RPE. Ten (n = 10) fit male runners completed a VO₂ max and two running trials, CAF (6 mg· kg^-1) vs. placebo (PLA). Participants ran a 2.4 km (1.5 m) bout, at prescribed RPE4, and another at prescribed RPE7, following 10 min passive recovery. Separate 2 (trial) x 6 …