Physiology Commons^™

A Descriptive Analysis Of Severe Maternal Morbidities In Southern Arizona, Joseph Sherman

Undergraduate Honors Theses

Introduction

Maternal morbidities and maternal deaths are rising at an alarming rate throughout the United States, despite advances in medicine and technology (Centers for Disease Control and Prevention [CDC], 2020). In 2020, maternal deaths climbed to its highest peak in thirty years, at 23.8 deaths per 100,000 births (CDC 2020; CDC 2022b). Maternal morbidities have also increased by nearly 200% from 1993 to 2014 (CDC, 2021). The startling rise in both maternal morbidities and maternal deaths is likely exacerbated by limited access to healthcare and the pervasiveness of chronic diseases such as obesity, diabetes, and heart disease (Carroll, 2017; Geller …

Determine Speed Performance Of Young Football Players Via Correlation Analyze, Shokhrukh Erkinov, Ildar Kushbakhtiev, Orif Erdonov, Vokhidjon Makhmudov

Karakalpak Scientific Journal

Problem Statement: Study the optimal relationship between the general and special speed performance of 14-17-year-old football players, taking into account their age characteristics and determining correlation relationship of the general and special speed performance.

Approach: As the object of the research, was chosen to study the development of general and special speed performance of 48 of football players of the SSOR (State school of the Olympic reserve, Tashkent city, Republic of Uzbekistan) aged 14 to 17 years, 12 football players in each group (total n=48).

Purpose: The research studies of the correlation relationship of general and special physical performance by …

Phenotypic Variability In Ipsc-Induced Cardiomyocytes And Cardiac Fibroblasts Carrying Diverse Lmna Mutations, Jiajia Yang

USF Tampa Graduate Theses and Dissertations

Mutations in the LMNA gene (encoding lamin A/C) are the second most common cause of familial arrhythmogenic cardiomyopathy. Diverse LMNA variants in cardiomyocytes have been associated with cardiac phenotypes. Moreover, cardiac fibroblasts make up a large fraction of the myocardium's non-myocyte component, intrinsically linked to extracellular matrix synthesis and turnover as well as secreting large amounts of bioactive metabolites. However, our understanding of how different mutation sites and the non-myocyte niche mediate cardiomyocyte function is limited. To fill this gap, in this thesis I investigated the hypothesis that variable LMNA mutations have significant effects on the genetic, structure and electrophysiological …

Differences In Stronger Versus Weaker Firefighters In Selected Measures Of Power, Quincy Johnson, J. Jay Dawes, Melissa Uftring, Marcel Lopes Dos Santos, Davis Hale, Gabriel J. Sanders, Will Peveler, Roger O. Kollock

International Journal of Exercise Science

International Journal of Exercise Science 15(4): 552-560, 2022. Firefighters are required to perform a wide array of physically demanding job tasks, such as forcible entry, charged hose advances and victim extractions. An adequate level of muscular strength and power are required to successfully perform these tasks. The purpose of this study is to investigate the differences in stronger and weaker firefighters in measures of power. Archived data for twenty-seven (age = 34.3 ± 7.9 yr, body height = 176.3 ± 7.2 cm, body mass = 89.4 ± 15.7 kg) full-time firefighters were analyzed. Participants were placed into one of two …

Effects Of Six-Week Periodized Versus Non-Periodized Kettlebell Swing Training On Strength, Power And Muscular Endurance, Evaldo Rui Tavares Santos Junior, Belmiro De Salles, Ingrid Dias, Roberto Simão, Jeff Willardson

International Journal of Exercise Science

International Journal of Exercise Science 15(4): 526-540, 2022. The purpose of this study was to compare a periodized versus a non- periodized protocol of kettlebell (KTB) swings over six weeks on strength, power, and muscular endurance. Twenty-eight high intensity functional training (HIFT) practitioners were assigned to non- periodized (NPG = 11), periodized (PG = 11), or control groups (CG = 6). NPG used the same load (20 kg) throughout the training period while the PG used a step loading progression (with an added four kilograms every two weeks). Measures of strength and muscular endurance in the deadlift exercise, and power …

Effect Of Different Numbers Of Interset Antagonist Proprioceptive Neuromuscular Facilitation Stretching On The Total Number Of Repetitions For The Agonists, Humberto Miranda, Aline Aparecida De Oliveira, Juliana Soares Dos Santos Ribeiro, Fabio Henrique De Freitas, Juliana Brandão Pinto De Castro, Renato L. Alvarenga, Jeff Willardson

International Journal of Exercise Science

International Journal of Exercise Science 15(4): 498-506, 2022. Recent studies have observed that stretching applied to antagonist muscles can promote improvement in agonist muscle performance. The purpose of this study was to investigate the effect of different numbers of interset proprioceptive neuromuscular facilitation (PNF) stretching for the antagonists on the total number of repetitions completed for the agonists (quadriceps) in the leg extension exercise. Fourteen physically active individuals (age: 29.35 ± 10.5 years; body mass: 79.1 ± 11.34 kg; height: 170.4 ± 8.7 cm) participated in this study. The following experimental protocols were performed: 1) Traditional protocol (Traditional) …

Pre-Exhaustion Training, A Narrative Review Of The Acute Responses And Chronic Adaptations, Thiago Trindade, Ragami Alves, Bruno De Castro, Matheus De Medeiros, Jason De Medeiros, Paulo Dantas, Jonato Prestes

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 507-525, 2022. Pre-exhaustion (PE) is a popular resistance training strategy that involves performing a single-joint exercise followed by a multi-joint exercise with minimal recovery between the transition. This approach is widely used by bodybuilding athletes and resistance training (RT) enthusiasts with the aim of enhancing muscle strength and hypertrophy. The present paper aimed to provide a narrative review as to the effects of the PE method on different acute and chronic outcomes, and discuss relevant practical applications. When considering the body of literature as a whole, we conclude that current evidence does not support …

Electromyographic Examination Of Hip And Knee Extension Hex Bar Exercises Varied By Starting Knee And Torso Angles, Edward Jo, Kevin A. Valenzuela, Whitney Leyva, Jennifer Rivera, Kalin Tomlinson, Elisabeth Zetiz

International Journal of Exercise Science

International Journal of Exercise Science 15(1): 541-551, 2022. Variations of the deadlift can be executed using the hexagonal (hex) bar by altering, for instance, the knee and torso angles while maintaining a constant hip angle at the start position. PURPOSE: To examine muscle activation patterns of the biceps femoris, rectus femoris, and erector spinae during three deadlift variations using the hex bar. METHODS: Twenty resistance-trained male and female subjects performed hex bar deadlift variations in three different starting knee flexion positions: 128.4 ± 8.5°, 111.9 ± 8.7°, and 98.3 ± 6.5°. Subjects performed three repetitions at 75% of their three-repetition …

In This Issue (13:4), Stephen J. Langendorfer Ph.D.

International Journal of Aquatic Research and Education

Greetings, IJARE readers and welcome to the fourth issue of Volume 13. I admit being quite excited about this issue. It is jam-packed with outstanding papers from six different countries that deserve your readership and attention.

Assessment Of Relationships Between External Load Metrics And Game Performance In Women’S Lacrosse, Libby Bynum, Ronald Snarr Jr., Bradley Myers 8931361, Jennifer A. Bunn

International Journal of Exercise Science

International Journal of Exercise Science 15(6): 488-497, 2022. The purpose of this study was to analyse the relationship between external load metrics with game performance for Division I collegiate female lacrosse. Data were collected using microtechnology during 26 games with 13 athletes (attackers n = 5, midfielders n = 8). External load variables included: total distance (TD), distance rate (DR), high-intensity (HI) distance, speed, HI sprints, accelerations, decelerations, metabolic equivalent distance (MED), and sprints. For attackers, goals, points, shots, and shots on goal (SOG) had low, positive associations with TD (r = 0.32 to 0.42) and MED (r …

Evaluating Novel Methods Of Classifying Interlimb Asymmetries Within Collegiate American Football Players, Nicolas M. Philipp, Derek A. Crawford, Matthew J. Garver, H. Scott Strohmeyer

International Journal of Exercise Science

International Journal of Exercise Science 15(6): 473-487, 2022. Over the last few years, researchers and sport scientists have expressed an increased interest in the effects of interlimb asymmetry on aspects of sport performance such as jumping, sprinting, and changing direction. This study aimed to evaluate the diagnostic utility of three different means of classifying asymmetry to highlight if a 6-week resistance training intervention can meaningfully reduce levels of asymmetry, and to determine the relation between asymmetry reduction and improvements in change of direction (CoD) performance, if any. Eighteen, division-two collegiate American football skill position players completed all pre- and post-intervention …

Acute Ingestion Of A Commercially Available Pre-Workout Supplement Improves Anaerobic Power Output And Reduces Muscular Fatigue, Sotiris Panayi, Andy Galbraith

International Journal of Exercise Science

International Journal of Exercise Science 15(6): 455-472, 2022. The effect of a pre-workout supplement on anaerobic power output and muscular fatigue was examined. 18 participants took part in this double-blinded crossover study, reporting for testing on 3 occasions. Participants completed a 6x6 second repeated sprint test, with 20s recovery between sprints. Anaerobic power output was recorded as the highest power achieved during sprint test. Muscular fatigue was reported as a fatigue index across the six sprints ((maximum power – minimum power) ÷ total sprint time). During a baseline visit, participants consumed 250ml of water 30 minutes prior to testing, whilst …

High-Risk Environmental Conditions Attenuates Performance Efficiency Index In Ncaa Di Female Soccer Players, Maxine Furtado Mesa, Jeffrey R. Stout, David H. Fukuda, Michael J. Redd, Adam J. Wells

International Journal of Exercise Science

International Journal of Exercise Science 15(6): 442-454, 2022. The purpose of this study was to evaluate the effects of environmental conditions on running performance and performance efficiency index (Effindex). Performance data recorded using Polar Team Pro sensors from eight collegiate female soccer players in nine matches were analyzed during the 2019 competitive season. Effindex and running performance, including total distance covered (TD_REL) and distance covered in five speed thresholds relative to minutes played, were examined for indications of fatigue with respect to environmental conditions, including ambient temperature and relative humidity. Matches were separated into three groups based on …

The Impact Of Early Morning Training Sessions On Total Sleep Time In Collegiate Athletes, Brandon Merfeld, Austin Mancosky, Joel Luedke, Shalynn Griesmer, Jacob Erickson, Victoria Carvalho, Andrew R. Jagim

International Journal of Exercise Science

International Journal of Exercise Science 15(6): 423-433, 2022. Early morning training sessions may affect sleep quantity in athletes. The purpose of this study is to examine differences in total sleep time of collegiate athletes on nights prior to early morning training sessions relative to non-training nights. Wristwatch monitors equipped with photoplethysmography and accelerometer technology were worn by 18 NCAA Division III collegiate athletes (Age: 20.1 ± 1.6 years, Height: 1.81 ± 0.02 m, Body Mass: 91.2 ± 6.5 kg, Body Fat %: 20.8 ± 1.6%) during a two-week period of training to monitor total sleep times. Athletes recorded time in …

Comparison Of A Continuous And Discontinuous Gxt On Vo2 In Resistance-Trained And Endurance-Trained Males, Brandon D. Shepherd, Ffion G. Price, Ben Krings, Johneric W. Smith

International Journal of Exercise Science

International Journal of Exercise Science 15(4): 414-422, 2022. Traditional graded exercise testing to assess maximal oxygen uptake (VO_2max) may not well represent resistance-trained athletes due to their unfamiliarity with continuous exercise. For this reason, it is possible discontinuous exercise protocols may better represent the maximum capacity for aerobic metabolism in resistance-trained athletes, in order to provide a more valid assessment of VO_2max and risk of developing cardiovascular disease. Purpose: The purpose of this experiment was to compare VO_2peak during a continuous and discontinuous modified Bruce protocol in both highly resistance-trained and endurance-trained males. Methods: 19 college-aged …

Is It Safe For Hemodialysis Patients To Seek Gains With Less Pain? Acute Hemodynamic Response To Intradialytic Blood Flow Restriction Training, Rony Nobre, Rodrigo Cardoso, Aline Araujo, Rafael Orcy, Jeniffer Aquino, Larissa Ribeiro, Rafaela Catto, Ana Carolina Conteratto, Airton Rombaldi, Maristela Bohlke

International Journal of Exercise Science

International Journal of Exercise Science 15(2): 434-441, 2022. Considering that the hemodynamic safety is a major concern about intradialytic exercise with blood flow restriction, this analysis was performed to compare the blood pressure (BP) behavior during the first two hours of hemodialysis (HD) between sessions with no exercise (control group, CG), low/moderate intensity aerobic exercise with blood flow restriction (BFRE) and conventional aerobic exercise (AE). Adult patients with chronic kidney disease on HD at a university hospital were randomly assigned and submitted to a 12-week intradialytic training with BFRE or AE compared with the CG group. The main outcomes of …

Role Of Bmi1 In Acute Lung Injury, María Helena Hernández-Cuervo

USF Tampa Graduate Theses and Dissertations

Acute Lung Injury (ALI) is a set of signs and symptoms that lead to acute hypoxemic respiratory failure characterized by bilateral pulmonary infiltrates not attributed to cardiogenic origin. It is caused by a massive innate immune response, with the migration of white blood cells (neutrophils and macrophages principally) and a cytokine storm, followed by alterations in mitochondrial function, increase in reactive oxygen species production, and oxidative stress that in turn induces more mitochondrial damage. Several studies have shown that mitochondrial alterations are key events in the mechanism of ALI and reducing mitochondrial dysfunction could be a possible target in the …

Lifeguard Performance Skills: A Systematic Review, Paulo Santiago, Filipe Maia, Sandra Santiago, Daniel Duarte, Pedro Teques

International Journal of Aquatic Research and Education

Drowning is one of the leading causes of death worldwide and lifeguards’ action can be regarded as a significant contribution to change that reality. In this regard, the purpose of this systematic review was to identify factors associated with lifeguards’ performance. After extensive research on PsycArticles, PsicBooks, PsycInfo, SportDiscus, Web of Science, PubMed, Scopus and SportDiscus databases, containing the keywords “lifeguard” AND “performance”, “lifeguard” AND “skills” and “lifeguard” AND “drowning”, we obtained 429 research articles. After eliminating duplicates, excluding those that had no relevance to the study, and screening against set criteria, a total of five articles were fully reviewed. …

Staying Hydrated: A Comparative Analysis Of Humectants In Human Skin, Ayden Olsen, Rachel Prince, Craig Reeves, Cassie Peterson, Jason Adams

Library/Life Sciences Undergraduate Poster Competition 2022

Humectants are an important class of compounds that attract and retain water within a cell. When mixed with water to create wetting solutions, humectants can prevent desiccation of cadaveric specimens. Recognizing a relative scarcity of comparative studies analyzing the effects of various wetting solutions on post preservation cadaveric maintenance, we utilized wet-dry analysis in order to compare the effects of four common humectants on water retention in human skin tissue. We created a concentration gradient for each humectant to identify the optimal concentrations of each compound for water retention, after which we compared water retention in tissue at the optimal …

A Ketogenic Diet Enhances Hippocampal Mitochondrial Efficiency, Cali E. Warren, Erin R. Saito, Benjamin T. Bikman

Library/Life Sciences Undergraduate Poster Competition 2022

Mitochondrial dysfunction and cognitive impairment are common symptoms in many neurologic disorders, as well as in nonpathological aging. Ketones have been suggested as therapeutic for their relevance in epilepsy and other neurodegenerative diseases and psychiatric disorders such as Alzheimer’s and Parkinson’s disease, schizophrenia, and major depressive disorder.

New Treatment For Multiple Sclerosis Could Halt Disease Progression Without Weakening Immune System, Carter Helquist, Dario Mizrachi

Library/Life Sciences Undergraduate Poster Competition 2022

• Multiple Sclerosis (MS) is a debilitating neurological and autoimmune disease in which immune cells cause demyelination of axons in nervous tissue.
• Current treatments for the disease are principally aimed at weakening the immune system to therefore weaken the autoimmune attack on the brain. This leaves patients prone to other sicknesses.
• We seek a treatment that prevents the immune cells from entering the central nervous system (CNS) thereby protecting its cells.
• We can prevent immune cells from entering the CNS by strengthening the blood brain barrier through targeting claudin 5 proteins in the tight junctions.
• This new treatment could mean increased …

Chimeric Claudins Reveal Role In Neural Tube Defects, Wesley Allen, Nathan Beckett, Emma Brenchley, Jacob Wengler, Lauren Hall, Cailey Winn, Meredith Mann, Sion Jung, Spencer Thacker, Rachel May, Dario Mizrachi, Micheal Stark

Library/Life Sciences Undergraduate Poster Competition 2022

Claudins (CLDN), a family of proteins found in the tight junction, play a major role in membrane permeability. While claudin disruption is known to contribute to the formation of neural tube defects (NTD), current research methods rely heavily on a non-specific toxin, CPE, when exploring the importance of CLDNs within neural tube formation. This makes it difficult to identify individual CLDN’s contribution to NTD formation, creating a need for a more specific method.

Hsp90 Inhibitors Modulate Sars-Cov-2 Spike Protein Subunit 1-Induced Human Pulmonary Microvascular Endothelial Activation And Barrier Dysfunction, Ruben Manuel Luciano Colunga Biancatelli, Pavel Solopov, Betsy W. Gregory, Yara Khodour, John D. Catravas

Bioelectrics Publications

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused more than 5 million deaths worldwide. Multiple reports indicate that the endothelium is involved during SARS-Cov-2-related disease (COVID-19). Indeed, COVID-19 patients display increased thrombophilia with arterial and venous embolism and lung microcapillary thrombotic disease as major determinants of deaths. The pathophysiology of endothelial dysfunction in COVID-19 is not completely understood. We have investigated the role of subunit 1 of the SARS-CoV-2 spike protein (S1SP) in eliciting endothelial barrier dysfunction, characterized dose and time relationships, and tested the hypothesis that heat shock protein 90 (HSP90) inhibitors would prevent and repair such injury. S1SP …

An Interactive Game With Virtual Reality Immersion To Improve Cultural Sensitivity In Health Care, Paul J. Hershberger, Yong Pei, Timothy N. Crawford, Sabrina M. Neeley, Thomas Wischgoll, Dixit B. Patel, Miteshkumar M. Vasoya, Angie Castle, Sankalp Mishra, Lahari Surapaneni, Aman A. Pogaku, Aishwarya Bositty, Todd Pavlack

Health and Sport Science Faculty Publications

Purpose: Biased perceptions of individuals who are not part of one's in-groups tend to be negative and habitual. Because health care professionals are no less susceptible to biases than are others, the adverse impact of biases on marginalized populations in health care warrants continued attention and amelioration.Method: Two characters, a Syrian refugee with limited English proficiency and a black pregnant woman with a history of opioid use disorder, were developed for an online training simulation that includes an interactive life course experience focused on social determinants of health, and a clinical encounter in a community health center utilizing virtual reality …

Harnessing Blood Clot Removal Mechanisms After Germinal Matrix Hemorrhage, Jerry J. Flores

Loma Linda University Electronic Theses, Dissertations & Projects

Germinal matrix hemorrhage (GMH) is one of the leading causes of morbidity, mortality, and acquired infantile hydrocephalus in preterm infants in the United States, with little progress made in its clinical management. Blood clots have been shown to elicit secondary brain injury after GMH, by disrupting normal cerebrospinal fluid circulation and absorption after germinal matrix hemorrhage causing post-hemorrhagic hydrocephalus development. Current evidence suggests that rapid hematoma resolution is necessary to quickly improve neurological outcomes after hemorrhagic stroke. N-formyl peptide receptor 2 (FPR2), a G-protein-coupled receptor, has been shown to be neuroprotective after stroke. FPR2 activation has been associated with the …

Relating Metabolic Phenotypes To Movement Behavior In Brook Trout, Jacob E. Bowman

All NMU Master's Theses

Brook trout movement-related life history strategies vary considerably and range from individuals that stay within the same 100 meters their entire life to individuals that are potamodromous or anadromous. Potential drivers of movement life histories have been the subject of much research in fish, with genetic subpopulation explanations often failing to explain the phenomenon. Metabolic phenotypes have been suggested as a possible driver for expression of different movement life histories. I investigated if metabolic phenotypes are related to movement strategies within a population of brook trout (Salvelinus fontinalis) in Unnamed Creek, a tributary to the Rock River, Alger …

Parent Motivational Climate, Sport Enrollment Motives, And Young Athlete Commitment And Enjoyment In Year-Round Swimming, Rachel E. Williams, Christine M. Habeeb, Thomas D. Raedeke, Dee Dlugonski, Katrina D. Dubose

International Journal of Exercise Science

International Journal of Exercise Science 15(5): 358-372, 2022. Parents are known to influence the athlete sport experience through motivational climates. Athletes’ perception of motivational climates and their own motives for sport participation influence enjoyment and long-term sport commitment. It is unknown, however, the extent parent motives for initially enrolling their child in a year-round sports program associate with children’s sport participation enjoyment and commitment. The purposes of this study were to (a) determine parent motives for enrolling their child (5-8 years) in year-round swimming and (b) explore the relationships of parent motives and motivational climates with child enjoyment and commitment. …

Validation Of A New Ramping Aerobic Exercise Protocol (Ndks) In Overweight, Obese, And Normal Weight Individuals, Jill K. Nustad, Mckaela E. Halvorson, Alexa L. Scott

International Journal of Exercise Science

International Journal of Exercise Science 15(4): 386-398, 2022. The research purpose was to establish reliability and validity of determining VO_2max via a new NDKS (Nustad Dressler Kobes Saghiv; named for the sir names of department faculty at the time) ramping protocol compared to the Standard Bruce protocol in normal weight, overweight, and obese individuals. Forty-two physically active participants (23M, 19F) ages 18-28 years were grouped into normal weight (N = 15, 8F, BMI 18.5-24.9 kg/m²), overweight (N = 27, 11F, BMI = 25-29.9 kg/m²), and Class I obese (N = 7, 1F, …

Effect Of Different Training Programs At Self-Selected Intensity On Body Composition, Perceptual Responses And Fitness Outcomes In Obese Women, Ragami Chaves Alves, Alysson Enes, Lucio Follador, Jonato Prestes, Sérgio Gregório Da Silva

International Journal of Exercise Science

International Journal of Exercise Science 15(4): 373-385, 2022. Obesity induces several disorders, such as android obesity, insulin resistance, and coronary/peripheral artery disease, and obese individuals commonly have low adherence to training programs. Exercise at self-selected intensity is a feasible strategy to avoid dropouts of training routines. We aimed to assess the effects of different training programs at self-selected intensity on body composition, ratings of perceived exertion (RPE), feelings of pleasure and displeasure (FPD) and fitness outcomes (maximum oxygen uptake (VO2max) and maximum dynamic strength (1RM)) in obese women. Forty obese women (n = 40; Body Mass Index: 33.2 ± …

Acute Effects Of Velocity-Based Resistance Training On The Physical Functional Performance Of Older Adults, Suzy S. Pinto, Ewertton S. Bezerra, Keuly G. Silva, Rodrigo Ramirez-Campillo, Abderaouf B. Abderrahman

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 399-413, 2022. The aim of this study was to analyse the acute effects of velocity-based resistance training on the physical and functional performance of older adults. Twenty participants (70.4 ± 7.4 years) performed the deadlift exercise, in two different resistance training protocols. The moderate-velocity protocol (MV) predicted maximum loads so that the movement velocity during the concentric phase remained in the range of 0.5 to 0.7 m/s and the high-velocity protocol (HV) predicted maximum loads so that the movement velocity remained between 0.8 and 1.0 m/s. The jump height (cm), handgrip strength (kg), and …