Physiology Commons^™

Physiological And Psychological Responses To Six Weeks Of High-Intensity Interval And Moderate-Intensity Continuous Training In Physically Inactive Young Adults, Emily R. Dunston

EWU Masters Thesis Collection

High-intensity interval training (HIIT) has been proposed as a public health strategy to promote physical activity; yet, there is limited evidence examining factors related to adherence to HIIT.

PURPOSE: To determine the effect of six weeks of HIIT and moderate-intensity continuous training (MICT) on physiological and psychological responses to training.

METHODS: Physically inactive young adults (n = 20; age = 21.4 ± 2.2 years) were randomized to the HIIT or MICT group. Assessments of body composition, cardiorespiratory fitness (CRF), moderate-to-vigorous physical activity (MVPA) and sedentary behavior levels were completed prior to and following the intervention. Participants completed 18 training sessions …

Sport Specialization And Its Effects On Collegiate Athlete Injury Rate, Alexander Duane Yager

EWU Masters Thesis Collection

No abstract provided.

Comparison Of Lower Extremity Strength And Strength Symmetry Among U.S. Ski Team Sports, Benjamin J. Adams

EWU Masters Thesis Collection

Most research in ski sports performance, injury, and sport physiological demands focuses on alpine ski racing. Very little research is available describing aerial and moguls ski competitors. Purpose: Compare lower extremity strength limb symmetry index (LSI) and relative strength (RS) among alpine, mogul, and aerials ski competitors. Methods: Archival data from 156 males and females from the U.S. Ski Team at Olympic, World Cup, and national levels were analyzed to compare RS and LSI among ski sports. Strength data consisted of maximal isometric bilateral squat strength values from each leg independently. A 3x2x2 factorial ANOVA was conducted to determine differences …

Evaluation Of The Use Of Alternative Biomarkers As Indicators Of Post-Release Mortality In Blacktip Sharks (Carcharhinus Limbatus), Casey L. Zender

UNF Graduate Theses and Dissertations

The release of sharks caught in recreational fisheries or as by-catch in non-target commercial fisheries is generally regarded as a sustainable fishing approach. However, post-release mortality can occur in these fish due to physiological damage sustained during capture. It is important to determine the amount of mortality specifically attributed to capture so losses can be accounted for in population management practices. Previous studies have used electronic tagging and/or measurement of secondary stress indicators in plasma (e.g., pH, levels of lactate, glucose, pCO₂) to estimate rates of post-release mortality. These methods may not always be the best approaches, as …

Functional Analysis Of Fam83d And Dupd1 – Two Novel Neruogenic Skeletal Muscle Atrophy-Induced Genes, Lisa Michelle Cooper

UNF Graduate Theses and Dissertations

Fam83d and Dupd1 have been identified as novel genes in skeletal muscle that are upregulated in response to neurogenic atrophy in a mouse model. qPCR analysis reveaed both genes are expressed in skeletal muscle with Fam83d expression being highest during myoblast proliferation, while Dupd1 expression is highest during myotube differentiation. Overexpression of either protein results in inhibition of proper muscle cell differentiation as evidenced by repression of both myosin heavy chain and myogenin expression. Characterization of transcriptional activity revealed both genes are modulated by myogenic regulatory factors and additionally, Dupd1 expression is enhanced by dexamethasone treatment. Assessment of subcellular localization …

Basigin As An Immune Mediator In The Cns, Alicia Gonzalez

UNF Graduate Theses and Dissertations

Chronic inflammation is a hallmark of many neurodegenerative disorders. Although the central nervous system (CNS) can stave peripheral pathogens from crossing the blood-brain barrier (BBB) through a network of continuous endothelia, astrocytes, and pericytes, prolonged exposure to a pathogen can comprise this barrier. Basigin, a cell adhesion molecule, is found on the surface of endothelial cells and has been demonstrated to interact with toll-like receptor 4 (TLR4). TLR4 recognizes lipopolysaccharide (LPS), found on the outer membrane of Gram-negative bacteria. The activation of TLR4 produces pro-inflammatory cytokines, like IL-6. The present study aims to address the expression pattern of Basigin gene …

The Immunological Response To Chronic Stress In Obese Mice, Matthew Corey Parsley

Graduate Theses, Dissertations, and Problem Reports (ETD)

Obesity and psychological stress are major risk factors for cardiovascular disease and have a positive correlation with vascular dysfunction. This functional deficit has been linked to a pro-inflammatory milieu, exacerbated by an upregulation of pro-inflammatory cytokines. Febuxostat, a xanthine oxidase inhibitor, has been shown to rescue vascular impairment in these models. The purpose of this study was to examine the individual and combined effects of obesity and chronic stress on neuroimmune cell populations, and assess if febuxostat is able mediate immune alterations.

Male mice (n=48) were assigned into either normal chow (lean) and high-fat diet (obese) groups. The lean animals …

Acute Physiological Responses To Arm-Cranking With Blood Flow Restriction, Benjamin Cockfield

Dissertations, Master's Theses and Master's Reports

Physiological responses to aerobic blood flow restriction exercise (BFR) are well documented for lower-body exercise but not upper-body exercise. I evaluated cardiorespiratory (heart rate, VO2, RER, ventilation), metabolic (tissue saturation, deoxyhemoglobin concentrations), and perceptual (effort, pain) responses to arm cranking with BFR at varying arterial occlusion pressures (AOP). Ten adults performed 4 intermittent arm cranking protocols (6x2-min, 1-min recovery): 1) low load (LL) – 40%VO2peak and 0% AOP; high load (HL) – 80%VO2peak and 0% AOP; (BFR50) – 40%VO2peak with 50% AOP; (BFR70) – 40%VO2peak with 70% AOP. Heart rate, RER, and ventilation, were higher with BFR compared to LL …

Spinal Motor Neuron Excitability And Balance Control Changes Following Downslope Walking, Nikki Aitcheson-Huehn

Theses and Dissertations (Comprehensive)

Downslope walking (DSW) has been proposed as a rehabilitation tool for people with Multiple Sclerosis (PwMS) although there are mixed findings in young adults (YA) regarding the balance control changes, despite both populations experiencing depressed spinal motor neuron (MN) pool excitability. Our aim was to determine whether YAs could demonstrate improved balance control in conjunction with SOL H reflex depression (estimate of spinal MN excitability) following DSW. We also aimed to determine whether reciprocal inhibition was a potential mechanism for H reflex depression via conditioned SOL H reflexes. Thirty young adults (23±1.4y, 6 males) were assigned to 30-minutes of DSW …

Muscle Soreness And Damage During Wildland Firefighter Critical Training, Katherine Sue Christison

Graduate Student Theses, Dissertations, & Professional Papers

Introduction: Wildland firefighters (WLFF) undergo a critical training (CT) period immediately before the firefighting season. The intensity of CT exercise could lead to muscle damage, as previously reported cases of rhabdomyolysis in WLFFs have been documented. This study established the effects of activities performed during a two-week CT period on acute markers of muscle damage in WLFFs.

Methods: 18 male and 3 female Type I Interagency Hotshot WLFFs were studied during a 14-day critical training period. Upper- (US) and lower-body (LS) muscle soreness and daily body weight (BW) scales were collected. Venous blood was collected on Days 1, 4, 8, …