Physiology Commons^™

Dim Light Exposure Or Melatonin Ingestion Lowers A Type 2 Diabetic's Blood Glucose Removal Rate: A Single Case, Matthew C. Scott, Arnold G. Nelson, Christopher M. Hearon

International Journal of Exercise Science

International Journal of Exercise Science 12(2): 1161-1168, 2019. The purpose of this case study isto compare a Type 2 diabetic's postprandial glucoregulatory ability under two different room lighting conditions. The subject was a 56-year-old physically active male with well controlled blood glucose levels (HbA1c ≤ 6% for 5 y) from a combination of diet, exercise, and medication. Two hours post evening meal (380 kcal, 18 g fat, 44 g carbohydrate, 12 g protein), a 45 g carbohydrate challenge was given, and blood glucose was measured every 30 minutes for 2.5 hours under three conditions: dim light (<50 lux) (DL), bright light (>40000 lux) …

Effects Of A Game-Centered Health Promotion Program On Fall Risk, Health Knowledge, And Quality Of Life In Community-Dwelling Older Adults, Alyssa K. Dispennette, Mark A. Schafer, Matthew Shake, Brian Clark, Steven Vanover, Gretchen B. Macy, K. Jason Crandall

International Journal of Exercise Science

International Journal of Exercise Science 12(4): 1149-1160, 2019. Quality of life (QOL) is an important aspect of overall well-being in older adults and can be improved with increased physical activity. One in four older adults experiences a fall each year, making it necessary to focus public health interventions towards decreasing fall risk and improving QOL in older adults. The purpose of this study was to determine the effects of the health promotion program, Bingocize^®, on QOL and fall risk in community-dwelling older adults (n = 36; mean age 73.63 ± 6.97). Participants were clustered and randomly assigned …

Kisspeptin And Attributes Of Infertile Males And Females: A Cross-Sectional Study In A Subset Of Pakistani Population, Rehana Rehman, Syeda Sadia Fatima, Faiza Alam, Mussarat Ashraf, Shaheen Zafar

Department of Biological & Biomedical Sciences

Kisspeptin, a peptide hormone, plays a pivotal role in fertility and neuroendocrine regulation of hypothalamo-pituitary-gonadal axis. Increased kisspeptin and reproductive hormones are responsible for fertility in male and females. This study aimed to explore the role of kisspeptin on hypothalamo-pituitary-gonadal axis by comparing the levels of kisspeptin in fertile and infertile subjects and identifying single nucleotide polymorphisms (SNPs) of KISS1 gene in exon 2 and exon 3 of infertile male and female cohorts. A cross-sectional study was carried out on 80 males (44 infertile and 36 fertile) and 88 females (44 in each group). Significantly high levels of kisspeptin (KP), …

Uga Anatomy And Physiology 2 Lab Manual, 3rd Edition, Ann Massey, Lindsey Beebe, Deloris Hesse

Biological Sciences Open Textbooks

This lab manual was created for Anatomy and Physiology II at the University of Georgia under a Textbook Transformation Grant and revised through a Scaling Up OER Pilot Grant.

http://oer.galileo.usg.edu/biology-collections/12/

The manual contains the following labs:

• Blood Composition
• Blood Typing
• Heart Anatomy
• Cardiovascular Physiology
• Systemic Blood Vessels
• Anatomy of the Respiratory System
• Physiology of the Respiratory System
• Renal Anatomy
• Urinalysis
• Digestive System Anatomy
• Digestive Physiology
• Male Reproductive System
• Female Reproductive System

Accessible files with optical character recognition (OCR) and auto-tagging provided by the Center for Inclusive Design and Innovation.

The Fitness Landscape Of The African Salmonella Typhimurium St313 Strain D23580 Reveals Unique Properties Of The Pbt1 Plasmid, Rocío Canals, Roy R. Chaudhuri, Rebecca E. Steiner, Siân V. Owen, Natalia Quinones-Olvera, Melita A. Gordon, Michael Baym, Michael Ibba, Jay C. D. Hinton

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

We have used a transposon insertion sequencing (TIS) approach to establish the fitness landscape of the African Salmonella enterica serovar Typhimurium ST313 strain D23580, to complement our previous comparative genomic and functional transcriptomic studies. We used a genome-wide transposon library with insertions every 10 nucleotides to identify genes required for survival and growth in vitro and during infection of murine macrophages. The analysis revealed genomic regions important for fitness under two in vitro growth conditions. Overall, 724 coding genes were required for optimal growth in LB medium, and 851 coding genes were required for growth in SPI-2-inducing minimal medium. These …

Anthropomorphic Denial Of Fish Pain, Lynne U. Sneddon, Matthew C. Leach

Lynne Sneddon, PhD

Key (2016) affirms that we do not know how the fish brain processes pain but denies — because fish lack a human-like cortex — that fish can feel pain. He affirms that birds, like fish, have a singly-laminated cortex and that the structure of the bird brain is quite different from that of the human brain, yet he does not deny that birds can feel pain. In this commentary we describe how Key cites studies that substantiate mammalian pain but discounts the same kind of data as evidence of fish pain. We suggest that Key's interpretations are illogical, do not …

Excess No Stabilizes The Luminal Domain Of Stim2 In A Cys-Specific Manner Thereby Regulating Basal Calcium Homeostasis And Store-Operated Calcium Entry, Matthew Novello

Electronic Thesis and Dissertation Repository

Stromal-interaction molecule 2 (STIM2) is an endoplasmic reticulum (ER) membrane-inserted Ca²⁺-sensing protein which, together with the plasma membrane Ca²⁺ channel Orai1, regulates basal Ca²⁺ homeostasis and store-operated Ca²⁺ entry (SOCE). Recent evidence suggests that S-nitrosylation, which is the covalent attachment of a nitric oxide (NO) moiety to a cysteine thiol, can attenuate the function of the paralog STIM1 protein. Compared to STIM1, STIM2 also functions as a basal Ca²⁺ homeostatic feedback regulator. Therefore, the objective of my study was to evaluate the susceptibility of STIM2 to S-nitrosylation and the effects that this …

Ankle And Midtarsal Joint Quasi-Stiffness During Walking With Added Mass, Andrew M. Kern, Nikolaos Papachatzis, Jeffrey M. Patterson, Dustin A. Bruening, Kota Z. Takahashi

Journal Articles

Examination of how the ankle and midtarsal joints modulate stiffness in response to increased force demand will aid understanding of overall limb function and inform the development of bio-inspired assistive and robotic devices. The purpose of this study is to identify how ankle and midtarsal joint quasi-stiffness are affected by added body mass during over-ground walking. Healthy participants walked barefoot over-ground at 1.25 m/s wearing a weighted vest with 0%, 15% and 30% additional body mass. The effect of added mass was investigated on ankle and midtarsal joint range of motion (ROM), peak moment and quasi-stiffness. Joint quasi-stiffness was broken …

Energy Cost Of Land And Shallow Water Walking In Females Who Are Overweight And Obese, Jacquelyn N. Zera, Elizabeth F. Nagle, Bethany B. Gibbs, John P. Abt, John M. Jakicic

International Journal of Aquatic Research and Education

Nineteen overweight or obese females completed three 10-minute experimental trials including a self-selected pace shallow water walking trial, a matched heart rate response land walking trial, and a self-selected pace land walking trial. Energy expenditure (kcal·min^-1)was computed from expired gases assessed via indirect calorimetry. Results showed energy expenditure was lower (p= 0.046) during shallow water walking (6.46 ± 1.38 kcal·min^-1) compared to matched heart rate response land walking trial (7.26 ± 1.29 kcal·min^-1), with no significant difference in between shallow water and self-selected pace land walking (6.92 ± 1.61 kcal·min^-1). …

Does Fatigue Impact Static And Dynamic Balance Variables In Athletes With Previously Ankle Injury?, Michelle Lacey, Bernard Donne

International Journal of Exercise Science

International Journal of Exercise Science 12(3): 1121-1137, 2019. Ankle injury, resulting in deficits in static and dynamic balance, can result in significant time loss to sport, affect daily activities and potentially place athletes at greater risk of re-injury. In order to identify athletes at risk of ankle injury accurate and reliable balance assessment tools are required. The purpose of the current study was to quantify reliability of static and dynamic balance variables in currently healthy, previously injured, athletes (n = 19) and assess the impact of an intense intermittent zig-zag running protocol to volitional exhaustion, rated by RPE, on balance …

The Effect Of Barefoot Running On Emg Activity In The Gastrocnemius And Tibialis Anterior In Active College-Aged Females, Ryan Beierle, Phoebe Burton, Hayden Smith, Michael Smith, Stephen J. Ives

International Journal of Exercise Science

International Journal of Exercise Science 12(1): 1110-1120, 2019. Running is one of the most popular forms of exercise, thus overuse injuries such as plantar fasciitis, shin splints, and tibial stress fractures are also common. Barefoot/forefoot running has shown promise to reduce overuse injuries by decreasing the impact upon contact with the ground. The arch of the foot utilizes a ‘spring’ system that simultaneously reduces impact and propels the stride forward. Increased muscle activity in a particular location is indicative of greater impact forces, suggesting a larger risk for overuse injuries. The current study investigated the role of the barefoot condition …

Emg Analysis Of The Neuromuscular Activity During Sit-To-Stand From Different Height Chairs In Water, Antonio Cuesta-Vargas

International Journal of Aquatic Research and Education

The purpose of this study was to use surface electromyography to measure the muscular activity during the sit-to-stand task in water and compare it at three different chair heights. Ten healthy young adults [5 males and 5 females (mean ± SD): age, 22.0 ± 3.1 yr; height, 172.8 ± 9.0 cm; body mass, 63.9 ± 17.2 kg] were recruited for study. We used a telemetry EMG system on the following muscles on the right side of the body: quadriceps (vastus medialis and rectus femoris), long head of the biceps femoris, tibialis anterior, gastrocnemius medialis, soleus, rectus abdominis, and erector spinae). …

Early Timeline Of Lean Tissue Mass And Strength Improvements In Trained Men Following A High Volume/Frequency Resistance Training Program, Michael H. Thomas, Robert H. Ferguson, Steve P. Burns, Natalie B. Allen

International Journal of Exercise Science

International Journal of Exercise Science 12(4): 1094-1109, 2019. The purpose of this study was to determine the early timeline effect of a systemic high volume/frequency resistance training intervention on lean tissue mass and strength in trained men. Twenty-two healthy resistance trained men, age (32.29 ± 9.75 years), training age (9.40 ± 6.18 years) were placed on a 4-week resistance training (RT) intervention with lean mass and strength assessed pre, mid, and post intervention. RT consisted of 6 exercises: flat smith chest press, pull ups, triceps pushdowns, dumbbell bicep curls, leg press or walking lunges, and standing calf raises, completing 5 …

Comparison Of Body Composition Prediction Equations With Air Displacement Plethysmography In Overweight And Obese Caucasian Males., Carley A. Shannon, Justin R. Brown, Andrew T. Del Pozzi

International Journal of Exercise Science

Body mass index (BMI) has been used for years by clinicians to approximate total body fat. However, the body adiposity index (BAI), body adiposity index from the FELS longitudinal study (BAIFELS), and an equation developed by Deurenberg et al. (BFD) were created recently to offset BMI’s limitations and accurately estimate percent body fat (%BF). The prevalence of overweight and obese Caucasian men is increasing in the United States; currently, there is no established way to quickly and accurately predict their %BF. Purpose: To compare the existing %BF equations (BAI, BAIFELS, and BFD) to measured %BF via air displacement plethysmography (ADP) …

Building Community Through Mountain Biking: Blending Coopetition, Collaboration And Community, Andy R. Dotterweich, Brandi M. Eveland-Sayers

ETSU Faculty Works

No abstract provided.

A Comparison Of Lung Function Values Among A Scuba Diver Population And In Comparison To A Non-Diver Population, Gabriel C. Hutson, Jeremy D. Rentsch, Erin M. Eaton

Journal of the South Carolina Academy of Science

The purpose of this study was to investigate possible correlations between lung function values (PEF, IRV, ERV, and FVC) among a diver population, as well as in comparison to a non-diver population. Independent variables for both populations were biological sex, age, and weekly physical activity. Independent variables for the diver population were dive tenure, number of logged dives, certification level, and gas mixture used. A spirometry test was conducted to collect lung function values of both populations. Data from this study suggest a statistically significant relationship between diver and non-diver sex and FVC, diver age and ERV, diver sex and …

The Assessment Of Swimming And Survival Skills: Is Your Programme Fit For Its Purpose?, Paolo Di Paola

International Journal of Aquatic Research and Education

Assessment of swimming and survival skills is a crucial part of any swimming and lifesaving programme. Unfortunately, quite often, it is also the weakest part of the programme itself. Inadequate skills assessment and verification might lead to ineffective skills acquisition and development, to a false sense of safety and over confidence in the water that can be extremely dangerous. Assessor experience and observation skills, assessment methodology, and criteria are all closely inter-linked and their interaction will somehow determine the assessment outcomes. Our paper analyses some of the current issues in these areas of the assessment process, such as assessor’s lack …

First Responders' Narratives Of Drowning: Perceptions Of Family And Community Impacts And Policy Implications, John Wells Phd, Michael Bergin Phd, John Connolly B.Ed., Ma In Ed., Suzanne Denieffe Phd

International Journal of Aquatic Research and Education

This is an exploratory study of the impacts of drowning death on local communities and families in the Republic of Ireland as perceived by first responders. The impact of a death may be particularly stressful. The identified population of interest were members of the Garda and first responders from Community Rescue Boats Ireland. The principal data collection method was one-to-one narrative interviews followed by a focus group. Questioning involved asking interviewees to talk about specific events rather than providing general opinions. Community identity was a source of impact, an urban or rural setting was a significant factor, social media was …

Inhibition Of Mitochondrial Permeability Transition By Deletion Of The Ant Family And Cypd, Jason Karch, Michael J. Bround, Hadi Khalil, Michelle A. Sargent, Nadina Latchman, Naohiro Terada, Pablo M. Peixoto, Jeffery D. Molkentin

Publications and Research

The mitochondrial permeability transition pore (MPTP) has resisted molecular identification. The original model of the MPTP that proposed the adenine nucleotide translocator (ANT) as the inner membrane pore-forming component was challenged when mitochondria from Ant1/2 double null mouse liver still had MPTP activity. Because mice express three Ant genes, we reinvestigated whether the ANTs comprise the MPTP. Liver mitochondria from Ant1, Ant2, and Ant4 deficient mice were highly refractory to Ca2+-induced MPTP formation, and when also given cyclosporine A (CsA), the MPTP was completely inhibited. Moreover, liver mitochondria from mice with quadruple deletion of Ant1, Ant2, Ant4, and Ppif (cyclophilin …

Can Blood Flow Restricted Exercise Improve Ham:Quad Ratios Better Than Traditional Training?, Michael G. Bemben, Kirsten M. Mitcheltree, Rebecca D. Larson, David Ross, Charity Cavazos, Benjamin Friedlander, Debra A. Bemben

International Journal of Exercise Science

International Journal of Exercise Science 12(4): 1080-1093, 2019. Muscular deficiencies between the quadriceps and hamstrings are prevalent among women and often lead to knee injury and ACL tears. The purpose of this study was to examine whether short term resistance training with or without blood flow restriction (BFR) could improve hamstring:quadricep ratios (H:Q) and reduce the chance for injury. Women (n = 14; 18-25 yrs) were randomly assigned to either a traditional resistance training (RT: n = 8) or BFR resistance training in combination with traditional RT (RT+BFR: n = 6) group. Subjects trained 3 days/week for 6 weeks. …

Fetal Pig Dissection Manual (Biol 105), Nathalia G. Holtzman, Daniel J. Yakubov

Open Educational Resources

This book is a guide to the basic fetal pig dissection conducted as a part of the Queens College, CUNY Biology Department Bio105 General Biology: Physiology and Cell Biology course. This course is the first half our two-part series for biology majors. The actives are designed to be conducted over a three- 3-hour lab periods which focus on the relationship of form and function of the pig anatomy and physiology. Step by step instructions for the dissection are provided along with some microscopy tasks to look at the histology of key organs.

In addition to the full text of the …

Histology Atlas: Basic Mammalian Tissue Types (Biol 105), Joshua Barnes, Daniel J. Yakubov, Corinna Singleman, Nathalia G. Holtzman

Open Educational Resources

This book is a guide to the basic histology lab conducted as a part of the Queens College, CUNY Biology Department Bio105 General Biology: Physiology and Cell Biology course. This course is the first half our two-part series for biology majors. The actives are designed to be conducted over a single 3-hour lab periods which focus on the relationship of form and function of the cellular and organ level anatomy and physiology. Step by step instructions for each slide set are provided for all the key organs.

In addition to the full text of the book, we also provide a …

The Effect Of Moderate Intensity Aerobic Exercise On Affect And Exercise Intention In Active And Inactive College Students, Allison M. Kyral, Amber M. Shipherd, Christopher M. Hearon

International Journal of Exercise Science

International Journal of Exercise Science 12(5): 1070-1079, 2019. Physical activity has long been established as an essential behavior for vital physical and psychosocial health outcomes (16, 18), but lack of physical activity is still a rampant problem worldwide (7). Numerous factors influence physical activity participation, including affect, a measure of well-being. Research has found that affect increases following an exercise session, though some recent studies have discovered that affect tends to be lower when measured during exercise (14). Therefore, the purpose of this study was to explore the differences in affect between active and inactive college students during exercise. A …

Effects Of Short-Term High Versus Continuous Moderate Intensity Training On Insulin Resistance In Overweight And Obese Adults: A Randomized Controlled Trial, Tshidi Thaane, Ayesha Motala, Andrew Mckune

International Journal of Exercise Science

International Journal of Exercise Science 12(3): 1057-1069, 2019. In long-term exercise training studies ( > 6 weeks), improvements in insulin resistance (IR) are amplified by decreased body fat and/or increased cardio-respiratory fitness. This presents a challenge in studying the independent effects of exercise training. Our study purpose was to determine the effects of short-term continuous moderate intensity training (CMIT) and high intensity interval training (HIIT) on IR in overweight/obese adults. Participants were stratified into insulin sensitive (IS) and IR groups, and randomized into non-exercise control (CNT), CMIT and HIIT sub-groups that underwent baseline and post testing. Exercise sessions were 18-24 minutes …

Acute Effects Of A Multi-Ingredient Pre-Workout Supplement On 5-Km Running Performance In Recreationally-Trained Athletes, Daniel J. Lutsch, Clayton L. Camic, Andrew R. Jagim, Nora J. Johnston, Taylor L. Musgjerd

International Journal of Exercise Science

International Journal of Exercise Science 12(2): 1045-1056, 2019. The purpose of the present study was to examine the effects of an acute dose of a multi-ingredient pre-workout supplement on 5-km running performance and subjective measures of fatigue. Twenty aerobically-trained, males (n= 10, mean ± SD = 80.8 ± 6.1 kg) and females (n= 10, 64.5 ± 6.6 kg) completed two 5-km running races for time in a double-blind, cross-over fashion. During the first session, subjects were randomly assigned to ingest the supplement or placebo 30 minutes prior to running a 5-km race. The supplement contained multiple …

Assessing The Structure-Function Relationships Of The Apolipoprotein(A) Kringle Iv Sub-Type 10 Domain, Matthew J. Borrelli

Electronic Thesis and Dissertation Repository

Elevated plasma lipoprotein(a) (Lp(a)) is the most prevalent heritable risk factor in the development of cardiovascular disease. The apolipoprotein(a) (apo(a)) component of Lp(a) is strongly implicated in the pathogenicity of Lp(a). It is hypothesized that the inflammatory potential of Lp(a)/apo(a) is mediated by the lysine binding ability of the apo(a) kringle IV10 (KIV10) domain, along with its covalently bound oxidized phospholipid (oxPL). Using targeted mutagenesis, two novel null alleles for the LPA gene that generate non-secretable apo(a) species have been identified, resulting from amino acid substitutions in the KIV10 domain. A potential mechanism by which KIV10 oxPL modification is enriched …

Measures Of Fluid Loss During Surfing: A Preliminary Analysis In Recreational Surfers, Rudi A. Meir, Zachary James Crowley-Mchattan Dr, Lyndon O. Brooks, Blake Duncan, Christian Gorrie, Jeremy Sheppard

International Journal of Aquatic Research and Education

Surfing is a popular sport, but little is known about the extent to which recreational surfers experience fluid loss from this activity. The principal objective of this research was to estimate fluid loss during a surfing session through changes in pre- to post-session urine color (Ucol), urine osmolality (Uosm), and body mass (BM). Data were collected from 11 recreational surfers across 14 surf sessions conducted under various environmental (mean water temperature = 22.1 SD ± 2.3; range = 20-26^oC; air temperature range = 13.1-31.5^oC; relative humidity range = 37.5-88.1%) and surfing conditions (e.g. winter/summer, wave type, …

Effects Of Aerobic Exercise Modality On Cognition And Fitness In Breast Cancer Survivors, Julie A. Larsen, Judy Knuth

International Journal of Exercise Science

International Journal of Exercise Science 12(3): 1023-1033, 2019. Although cognitive dysfunction is a common occurrence among breast cancer survivors, there is no widely recognized intervention for this debilitating condition. The purpose of this study was to determine whether floor/step aerobics (FSA) and/or treadmill walking (TMW) interventions can improve outcomes when compared to standard care (STC). Recent breast cancer survivors participated in 12 weeks of FSA (n=8), TMW (n=7), or STC (n=10) with pre/post assessments of cognition and fitness. Interaction effects between group and time were assessed with repeated measures ANOVA. Throughout the extent of …

The Relationship Between Lower-Body Strength And Power, And Load Carriage Tasks: A Critical Review, Robin Marc Orr, J. Jay Dawes, Robert G. Lockie, Daniel Godeassi

International Journal of Exercise Science

International Journal of Exercise Science 12(6): 1001-1022, 2019. The purpose of this review was to critically appraise articles that have investigated the association between lower-body strength and power during load carriage in tactical personnel. Literature databases were searched with specific search terms, yielding 921 articles. Additional studies found from article reference lists were also assessed for eligibility. Out of these articles, 16 met the inclusion/exclusion criteria and were critically appraised. Articles were assessed by the Downs and Black evaluation tool with inter-rater agreement determined by Cohen’s kappa and final results graded according to the Kennelly quality grading system. Of the …

Prevalence Of Disordered Eating And Muscle Dysmorphia In College Students By Predominant Exercise Type, Taylor E. Lechner, Emily M. Gill, Madeleine J. Drees, Carrie M. Hamady, Mary-Jon Ludy

International Journal of Exercise Science

International Journal of Exercise Science 12(4): 1001-1012, 2019. Many young adults experience distorted body image and decreased body satisfaction. To attain more “ideal” bodies, negative alterations in eating and/or exercise habits are common. This study’s objective was to compare disordered eating and muscle dysmorphia in undergraduates who participate in aerobic-, anaerobic-, or flexibility-predominant exercise; mixed exercise; or no exercise. One hundred twelve undergraduate students (age 21.2 ± 4.8 years; BMI 25.0 ± 4.6 kg/m²) were recruited from the student union and recreation center. The Eating Attitudes Test (EAT-26), Muscle Dysmorphic Disorder Inventory (MDDI), and demographic/exercise questions were administered …