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2013

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Articles 61 - 90 of 471

Full-Text Articles in Physiology

Protein Kinase C Dependent Inhibition Of Kir3.2 (Girk2) Channel Activity And Its Molecular Determinants, Scott Adney Sep 2013

Protein Kinase C Dependent Inhibition Of Kir3.2 (Girk2) Channel Activity And Its Molecular Determinants, Scott Adney

Theses and Dissertations

Inwardly rectifying potassium (Kir) channels are critically important for regulating resting membrane potential in excitable cells, a job underscored by the severe pathophysiology associated with channel dysfunction. While all Kir channels require the activating lipid PIP2, many of these channels have diverse modulatory factors that couple to PIP2-dependent gating. Channels in the Kir3 (GIRK) family, in particular, have several co-activating elements, including G-protein betagamma subunits, ethanol, and sodium. During stimulation of Gq-coupled receptors, downstream activation of Protein Kinase C can phosphorylate and inhibit Kir3 channels, yet the mechanism of inhibition and phosphorylation sites are incompletely understood. We took a combined …

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Lipids And Vesicular Fusion (The Doorway To My Future), Brady Atwood, Dr. Dixon J. Woodbury Sep 2013

Lipids And Vesicular Fusion (The Doorway To My Future), Brady Atwood, Dr. Dixon J. Woodbury

Journal of Undergraduate Research

Exocytosis is the process by which a cell excretes intracellular substances into an extracellular space. Cells perform this by storing these substances in lipid membrane enclosed spheres called vesicles. These vesicles are brought to the inside surface of the cellular membrane where they are docked and primed for release upon the appropriate signal. When the signal occurs the vesicles fuse to the membrane releasing the stored material into the space around the cell. This is especially relevant in neuroscience as this is the process by which neurotransmitters are released into the synaptic cleft which then go on to stimulate/inhibit another …

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The Role Of Phob In The Phosphate Signaling Pathway, Eliza H. Norcross, Dr. William R. Mccleary Sep 2013

The Role Of Phob In The Phosphate Signaling Pathway, Eliza H. Norcross, Dr. William R. Mccleary

Journal of Undergraduate Research

Every living cell requires a means of sensing its environment and responding appropriately. Even a single cell needs to coordinate its functions to survive. One way cells process environmental stimuli is through signal transduction pathways. Types of signaling used in bacteria include two component systems. “Two component” refers to the two parts of the system, a histidine kinase and a response regulator. The bacterium E. coli uses a two component system called the phosphate signaling pathway to sense and respond to varying levels of phosphate in the environment.

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Cytokine Regulation Of Adrenal Secretion Of Dehydroepiandrosterone (Dhea), Edward C. Miner, Dr. Allan M. Judd Sep 2013

Cytokine Regulation Of Adrenal Secretion Of Dehydroepiandrosterone (Dhea), Edward C. Miner, Dr. Allan M. Judd

Journal of Undergraduate Research

The adrenal cortex releases aldosterone, cortisol, and dehydroepiandrosterone (DHEA) into the blood stream. The regulation of aldosterone and cortisol release by the adrenal gland is well studied. In contrast, little is known about the regulation of DHEA secretion. Since low plasma levels of DHEA are associated with the aging process, rheumatoid arthritis, and disease progression in HIV-infected individuals, it is medically significant to determine the mechanism of DHEA release from the adrenal gland.

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The Adrenal Cortex Cell Line H295r Releases Interleukin-6, Timothy E. Lindsay, Dr. Allan M. Judd Sep 2013

The Adrenal Cortex Cell Line H295r Releases Interleukin-6, Timothy E. Lindsay, Dr. Allan M. Judd

Journal of Undergraduate Research

Up to this point, the study of adrenal glands has utilized mostly rat and bovine models. However, in the research of human physiology, human models are preferable to animal models. But human adrenal glands are difficult to obtain, and when they are obtained, experiments often have limited sample sizes. In addition, human adrenal glands available for research are often functionally altered by disease. Also, donors with healthy adrenal glands may be administered multiple pharmacological agents which modify adrenal functions. These obstacles show how a model that provides an unlimited quantity of tissue with consistent secretion patterns would take precedent over …

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The Effects Of Neurotensin On The Rat Distal Colon, Rick Chainani Sep 2013

The Effects Of Neurotensin On The Rat Distal Colon, Rick Chainani

Theses and Dissertations

The enteric nervous system controls the gut through the release of specific neurotransmitter and neuromodulators at specific sites such as mucosal secretory cell or smooth muscle cell. In the present study, we have examined the response to one of these neurohumoral agents, Neurotensin, in the rat distal colon. Neurotensin is a paracrine and endocrine modulator of the digestive tract. Even though these effects have been seen in colonic preparations, there are very few functional studies of the effects of Neurotensin in the rat colon, especially the distal colon. In the current study we propose the following hypothesis that Neurotensin will …

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Winter Activity Of Bats In Cache, Juab And Utah Counties, Utah, Benjamin T. Jones, Dr. Duke S. Rogers Sep 2013

Winter Activity Of Bats In Cache, Juab And Utah Counties, Utah, Benjamin T. Jones, Dr. Duke S. Rogers

Journal of Undergraduate Research

Historically, studies of bat activity have been conducted during spring, summer and fall when migratory bats are most abundant and non-migratory bats are most active. Due to the high energy expenditure required to maintain body temperatures sufficient for flight (Fenton, 1992) and the low availability of aerial insects, (Whitaker and Rissler, 1992) activity levels decline markedly with the onset of winter and the corresponding fall in temperatures. Non-migratory bats conserve energy by hibernating through the winter. However, in previous winter surveys conducted in Southern Utah, five of sixteen species know to occur in that area were netted. (Hasenyager, 1980) Bats …

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Phylogenetic Analyses Of The Geographic Origin Of Stlv-I And Htlv-I With Extensive Sequence Sampling: Evidence For An African Origin With Subsequent Separate Viral Evolution In Asia And Africa, Chris R. Kelsey, Dr. Keith A. Crandall Sep 2013

Phylogenetic Analyses Of The Geographic Origin Of Stlv-I And Htlv-I With Extensive Sequence Sampling: Evidence For An African Origin With Subsequent Separate Viral Evolution In Asia And Africa, Chris R. Kelsey, Dr. Keith A. Crandall

Journal of Undergraduate Research

Human T-cell lymphotropic virus type I (HTLV-I) is a retrovirus believed to be the etiologic agent of adult T-cell leukemia/lymphoma (ATL) and HTLV-I -associated myelopathy/ tropical spastic paraparesis (HAM/TSP). HTLV-I is a member of a related group of retroviruses, known collectively as primate T-cell lymphotropic viruses (PTLV) which also include human T-cell lymphotropic virus type II (HTLV-II) and the simian T-cell lymphotropic virus type I (STLV-I). In an attempt to better understand phylogenetic relationships among geographically diverse strains of PTLV-I, and in the process gain more insight into the geographic origin of STLV-I and HTLV-I, a comprehensive study involving multiple …

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Pediatric Study To Determine The Extent Of Parasympathetic Reinnervation To The Human Heart Post Transplant, Aaron W. Jones, R. Paul Evans Sep 2013

Pediatric Study To Determine The Extent Of Parasympathetic Reinnervation To The Human Heart Post Transplant, Aaron W. Jones, R. Paul Evans

Journal of Undergraduate Research

Until recently, it had been assumed that following cardiac transplantation, nerve impulses to the heart were permanently disconnected. Within the past few years, multiple studies prompted by patient complaints, observations, and simple curiosity have proven the surprising fact that the accelerator (or sympathetic) nerves to the heart almost always regrow.1 Furthermore, in a large segment of the recipient population, the same is found for the sensory nerves which relay pain and oxygen supply status of the heart to the brain.2 These discoveries have led scientists worldwide on the search for evidence of the regrowth of the decelerator (or parasympathetic) nerves …

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Identifying Sheep Parentage By Polymorphic Genetic Markers In Suffolk Sheep, Jennifer A. Jerman, Robert L. Park Sep 2013

Identifying Sheep Parentage By Polymorphic Genetic Markers In Suffolk Sheep, Jennifer A. Jerman, Robert L. Park

Journal of Undergraduate Research

Polymorphic genetic markers aid in parentage testing among individuals of the same breed. Suffolk sheep randomly mate and the need for accurate, reliable, and rapid testing for resolution of such mating is mandatory for the animals’ record and further genetic production. Therefore, it is necessary to identify such matings of individuals.

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Computational Optogenetics: Empirically-Derived Voltage- And Light-Sensitive Channelrhodopsin-2 Model, John C. Williams, Jianjin Xu, Zhongju Lu, Aleksandra Klimas, Xuxin Chen, Christina M. Ambrosi, Ira S. Cohen, Emilia Entcheva Sep 2013

Computational Optogenetics: Empirically-Derived Voltage- And Light-Sensitive Channelrhodopsin-2 Model, John C. Williams, Jianjin Xu, Zhongju Lu, Aleksandra Klimas, Xuxin Chen, Christina M. Ambrosi, Ira S. Cohen, Emilia Entcheva

Department of Biomedical Engineering Faculty Publications

Channelrhodospin-2 (ChR2), a light-sensitive ion channel, and its variants have emerged as new excitatory optogenetic tools not only in neuroscience, but also in other areas, including cardiac electrophysiology. An accurate quantitative model of ChR2 is necessary for in silicoprediction of the response to optical stimulation in realistic tissue/organ settings. Such a model can guide the rational design of new ion channel functionality tailored to different cell types/tissues. Focusing on one of the most widely used ChR2 mutants (H134R) with enhanced current, we collected a comprehensive experimental data set of the response of this ion channel to different irradiances and voltages, …

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Up-Regulation Of Ddr2 And Mmp13 As A Mechanism Of Osteoarthritis, Allyson Merrell, Kenneth Merrell Sep 2013

Up-Regulation Of Ddr2 And Mmp13 As A Mechanism Of Osteoarthritis, Allyson Merrell, Kenneth Merrell

Journal of Undergraduate Research

Arthritis is a painful, debilitating disease that affects sixty-six million Americans (The Arthritis Foundation 2005). Osteoarthritis (OA) results in joint degeneration caused by cartilage erosion and synovial inflammation. While the causes of OA remain unclear, current evidence suggests that both mechanical and biochemical factors can initiate OA. Since ethical and practical issues limit the availability of human tissue in OA research it is necessary to use animal models. Mice with the disproportionate micromelia mutation (Dmm) exhibit histological characteristics similar to those of humans with OA. Current research suggests the heterozygous Dmm mouse (D/+) is a valid model for early-onset OA …

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Interfering Rna Activity In Adrenal Cortical Cells, Brian Powell, Dr. Allan Judd Sep 2013

Interfering Rna Activity In Adrenal Cortical Cells, Brian Powell, Dr. Allan Judd

Journal of Undergraduate Research

Before the turn of the century, biological research was taken by storm with the discovery of inhibitory RNA (RNAi). In 1995, Guo and Kemphues (Mello & Conte, 2004) stumbled into this discovery and were later awarded the Nobel Prize in science for their discovery. The discovery turned into a technique that is used to knock out genes with laser-like precision, and although the precision of RNAi has come into question recently, it is still a valued technique (Couzin, 2004). However, still in its infancy, the extent to which RNAi is used naturally in different tissues is unclear. To the extent …

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Classification Of Neuronal Nicotinic Acetylcholine Receptors In Rat Hippocampal Ca1 Interneuron Subpopulations Defined By Neuropeptide Y, Somatostatin, And Calcium-Binding Proteins Mrna Expression, Matt Peterson, Dr. Sterling Sudweeks Sep 2013

Classification Of Neuronal Nicotinic Acetylcholine Receptors In Rat Hippocampal Ca1 Interneuron Subpopulations Defined By Neuropeptide Y, Somatostatin, And Calcium-Binding Proteins Mrna Expression, Matt Peterson, Dr. Sterling Sudweeks

Journal of Undergraduate Research

Hippocampal interneurons are a particularly diverse population of cells. Classifying these interneurons has historically been difficult using traditional schemes such as anatomical morphology, action potential spiking pattern, and receptor pharmacology. More recently however, classification of interneurons by examining expression of neuropeptide Y, somatostatin, and calcium-binding proteins (Ca-BPs: parvalbumin, calbindin, and calretinin) has been promoted as an effective means for identifying subpopulations within the hippocampus. Categorization of the expression of neuropeptide Y, somatostatin, and Ca-BPs with the various types of nicotinic acetylcholine receptors (nAChRs) could provide information valuable for characterizing how various interneuron subpopulations function to modulate the overall activity of …

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Phospholipase A2 Activity In Cell Signaling Apoptotic Pathway, Vu Mai Phuong, Dr. John Bell Sep 2013

Phospholipase A2 Activity In Cell Signaling Apoptotic Pathway, Vu Mai Phuong, Dr. John Bell

Journal of Undergraduate Research

Secretory phospholipase A2 (sPLA2) is a secretory enzyme thought to mainly function in hydrolyzing membrane phospholipids in certain conditions of signaling induced by the immune system or hormone activity. sPLA2 is known to be implicated in inflammatory diseases, sepsis, adult respiratory distress syndrome, ischemia, cancer, atherosclerosis, pre-eclampsia, and gall stones; therefore, understanding its mechanism of action is an important step in helping other researchers determine therapeutic means for these diseases.

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Molecular Modeling Dynamics Simulations Of Botox And, Richard Swenson, David Busath Sep 2013

Molecular Modeling Dynamics Simulations Of Botox And, Richard Swenson, David Busath

Journal of Undergraduate Research

In general, research of the function of proteins involved in harmful diseases helps researchers who are investigating these diseases better understand part of their puzzle to be able to find solutions to these problems and often opens doors for new treatments of other disorders. For example, to reduce wrinkles, doctors inject patients with Botulinum Neurotoxin(BoTox). I would like to add to the world’s understanding of BoTox so that new procedures can be developed and the harmful effects of botulism can be reduced. My research of Phospholipase A-2 (sPLA2) will likewise add to knowledge of the function of this and other …

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A Comparison Of Two Assays For Measuring Serum Levels Of Thymidine Kinase In Breast Cancer Patients, Dedra A. Cutler, Dr. Kim L. O'Neill Sep 2013

A Comparison Of Two Assays For Measuring Serum Levels Of Thymidine Kinase In Breast Cancer Patients, Dedra A. Cutler, Dr. Kim L. O'Neill

Journal of Undergraduate Research

Thymidine Kinase 1 (TK1) is an enzyme involved in DNA repair and cell proliferation. Increased cell proliferation results in higher than normal levels of TK1. Because of this relationship, TK1 has recently been identified as a useful marker in breast cancer diagnosis and treatment.

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Merocyanine 540 Fluorescence In Apoptotic Lymphocytes, Kristen H. Parker, Dr. John D. Bell Sep 2013

Merocyanine 540 Fluorescence In Apoptotic Lymphocytes, Kristen H. Parker, Dr. John D. Bell

Journal of Undergraduate Research

Our research team in Dr. Bell’s laboratory has focused primarily on studying interactions between cell membranes and the enzyme secretory phospholipase A2 (sPLA2). This enzyme is able to distinguish between healthy cells and foreign or damaged cells, which it hydrolyzes. The purpose of my individual project was to use a specific fluorescent probe to study the mechanism for the selective susceptibility and degradation of cell membranes by sPLA2.

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Intestinal Nematodes Of Lake Trout (Salvelinusnamaycush): An, Sandra B. Bay, Dr. Richard A. Heckmann Sep 2013

Intestinal Nematodes Of Lake Trout (Salvelinusnamaycush): An, Sandra B. Bay, Dr. Richard A. Heckmann

Journal of Undergraduate Research

Recently, a non-endemic species of fish, Salvelinus namaycush, was introduced into Yellowstone Lake. These lake trout feed on the native cutthroat trout, an important food source for higher predators in the area. During routine examinations of the lake trout, an abnormally high infection of intestinal nematodes was discovered. These intestinal nematodes are also found in the endemic lake trout in nearby Lewis Lake, but at a lower level of infection.

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Transgenic Rescue Of Disproportionate Micromelia (Dmm) Mice, Lisa Higgenbotham, Dr. Robert Seegmiller Sep 2013

Transgenic Rescue Of Disproportionate Micromelia (Dmm) Mice, Lisa Higgenbotham, Dr. Robert Seegmiller

Journal of Undergraduate Research

Microinjection is a technique used to introduce DNA into the genome of an animal at the embryo stage. It is an effective way to insert replacement, or rescue, copies of a gene that the embryo may be lacking. In this study, I prepared purified copies of the mouse Col2a1 gene and microinjected them into the pronuclei of single-cell mouse embryos. Col2a1 encodes type II collagen, a major component of cartilage. Mice carrying one or two mutant alleles of Col2a1 are characterized by developmental abnormalities, degenerative joint disease, and even death. This phenotype is observed in Disproportionate micromelia (Dmm) mice, which …

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The Effect Of Estrone On The Interaction Between Phospholipase A And The Phospholipid Bilayer, Eric M. Troxell, Marci L. Troxell, Dr. Marci L. Troxell, John D. Bell Sep 2013

The Effect Of Estrone On The Interaction Between Phospholipase A And The Phospholipid Bilayer, Eric M. Troxell, Marci L. Troxell, Dr. Marci L. Troxell, John D. Bell

Journal of Undergraduate Research

Phospholipase A is a protein that interacts reversibly with the phospholipid bilayer of cell membranes. This interaction is affected by physical alterations in the bilayer, which can be caused by a variety of sources, including temperature and certain drugs. Cholesterol is one of the sources known to change the physical properties of the bilayer. It was hypothesized that estrone (Cl8H2202), which is similar in structure to cholesterol, would also affect the bilayer. Studying the effects of various drugs on the bilayer and phospholipase A2 can lead to greater understanding of the lipid/protein interactions occurring in cells.

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The -9/+9 Polymorphism Of The Bradykinin Receptor Beta 2 Gene And Athlete Status: A Study Involving Two European Cohorts., Marek Sawczuk, Yevgeniya I. Timshina, Irina V. Astratenkova, Agnieszka Maciejewska-Karłowska, Agata Leońska-Duniec, Krzysztof Ficek, Leysan J. Mustafina, Paweł Cięszczyk, Tomasz Klocek, Ildus I. Ahmetov Sep 2013

The -9/+9 Polymorphism Of The Bradykinin Receptor Beta 2 Gene And Athlete Status: A Study Involving Two European Cohorts., Marek Sawczuk, Yevgeniya I. Timshina, Irina V. Astratenkova, Agnieszka Maciejewska-Karłowska, Agata Leońska-Duniec, Krzysztof Ficek, Leysan J. Mustafina, Paweł Cięszczyk, Tomasz Klocek, Ildus I. Ahmetov

Human Biology Open Access Pre-Prints

Background: Previous studies concerning the relevance of the BDKRB2 gene polymorphisms revealed that the absence (–9 allele) of a 9 base pair sequence in exon 1 of the BDKRB2 gene is correlated with higher skeletal muscle metabolic efficiency, glucose uptake during exercise, as well as endurance athletic performance. Aim: The aim of the study was to investigate the association between the BDKRB2 -9/+9 polymorphism and elite athletic status in two cohorts of east-European athletes. Therefore, we examined the genotype distribution of the BDKRB2 9/+9 polymorphic site in a group of Polish athletes and confirmed the results obtained in a replication …

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Retinal Detachment In Mice With Disproportionate Micromelia, Jared R. Jackson, Dr. Robert Seegmiller Sep 2013

Retinal Detachment In Mice With Disproportionate Micromelia, Jared R. Jackson, Dr. Robert Seegmiller

Journal of Undergraduate Research

Stickler syndrome, caused by a mutation of the Collagen 2A1 gene, is the most common cause of inherited retinal detachment in children. A mutation of the same gene in mice causes Disproportionate Micromelia (Dmm). “In cases where mouse mutations occur in genes that are also responsible for human disorders, the mouse strains provide essential model systems for studies of pathogenetic mechanisms.” The purpose of this study is to find and document evidence of retinal detachment that is hypothesized in heterozygous (Dmm/+) mutant mice.

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Understanding Actin To Stop Metastasis, James Moody, Ben Werner Sep 2013

Understanding Actin To Stop Metastasis, James Moody, Ben Werner

Journal of Undergraduate Research

The purpose of this project is to identify the organization and mechanism of the proteins in the Zyxin-VASP actin regulatory system using biochemical analysis and in vitro reconstitution.

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Chondrocyte Apoptosis Correlated With Progression Of Osteoarthritis In Dmm Mice, Ryan Anderson, Dr. Robert E. Seegmiller Sep 2013

Chondrocyte Apoptosis Correlated With Progression Of Osteoarthritis In Dmm Mice, Ryan Anderson, Dr. Robert E. Seegmiller

Journal of Undergraduate Research

Osteoarthritis (OA) is a progressive disease resulting in the degeneration of synovial joint cartilage and is the leading cause of chronic disability in the elderly1. Despite the prevalence of this disease, its pathogenesis is poorly understood. There is need for low cost, short generation animal model to study this disease. For this, we used a proven mouse model as the means for researching OA, the Disproportionate micromellia (Dmm) mouse which has been shown to develop early onset OA. One mechanism involved in OA that we are specifically researching is programmed cell death, apoptosis, of cartilage cells, chondrocytes and how it …

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Understanding Cancer Metastasis: The Role Of Zyxin In Actin Dynamics, Nicholas H. Bishop Sep 2013

Understanding Cancer Metastasis: The Role Of Zyxin In Actin Dynamics, Nicholas H. Bishop

Journal of Undergraduate Research

My research aims to elucidate the protein interactions at cell-cell contacts (adherens junctions or AJs) by studying the fluorescence recovery of three known AJ proteins (zyxin, VASP, and actin) after photobleaching. At AJs, zyxin interacts with VASP (Vasioukhin et al., 2000) which in turn encourages the polymerization of actin (Vasioukhin et al., 2000). Mutation of certain regions of zyxin may reveal their role in zyxin-VASP binding and regulation. The effects of altering VASP activity should be evident in actin turnover rate. In Fluorescence Recovery after Photobleaching (FRAP), regions of cell-cell adhesions with fluorescently labeled zyxin, VASP, or actin are bleached …

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Fetal Programming Of A Hyperactive Hypothalamic-Pituitary-Adrenal Axis, Joshua P. Thatcher, Dr. James P. Porter Sep 2013

Fetal Programming Of A Hyperactive Hypothalamic-Pituitary-Adrenal Axis, Joshua P. Thatcher, Dr. James P. Porter

Journal of Undergraduate Research

Cardiovascular diseases have become among the most widespread of adult diseases in the United States. Over the last few decades, the United States has experienced a dramatic increase in the rate of diseases such as Diabetes Mellitus Type II, Obesity and Hypertension.

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Aspirin And Low-Molecular Weight Heparin Combination Therapy Effectively Prevents Recurrent Miscarriage In Hyperhomocysteinemic Women., Pratip Chakraborty, Sayani Banerjee, Piyali Saha, Shyam Sundar Nandi, Sunita Sharma, Sourendra K. Goswami, Baidyanath Chakravarty, Syed N. Kabir Sep 2013

Aspirin And Low-Molecular Weight Heparin Combination Therapy Effectively Prevents Recurrent Miscarriage In Hyperhomocysteinemic Women., Pratip Chakraborty, Sayani Banerjee, Piyali Saha, Shyam Sundar Nandi, Sunita Sharma, Sourendra K. Goswami, Baidyanath Chakravarty, Syed N. Kabir

Journal Articles: Cellular & Integrative Physiology

The management of recurrent pregnancy loss (RPL) still remains a great challenge, and women with polycystic ovarian syndrome (PCOS) are at a greater risk for spontaneous abortion. Treatment with low-molecular-weight heparin (LMWH) has become an accepted treatment option for women with RPL; however, the subgroup of women, who are likely to respond to LMWH, has not been precisely identified. The present study evaluated the efficacy of LMWH with reference to PCOS and associated metabolic phenotypes including hyperhomocysteinemia (HHcy), insulin resistance (IR) and obesity. This prospective observational study was conducted at Institute of Reproductive Medicine, Kolkata, India. A total of 967 …

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Histological Validation Of Iron As An Imaging Biomarker For Amyloid Beta And Tau Depositions In Alzheimer’S Disease, Ashley Salin, Dr. Jonathan Wisco Sep 2013

Histological Validation Of Iron As An Imaging Biomarker For Amyloid Beta And Tau Depositions In Alzheimer’S Disease, Ashley Salin, Dr. Jonathan Wisco

Journal of Undergraduate Research

At present, no one can diagnose a patient with Alzheimer’s disease until postmortem examination. It was our goal to change that theory and make it possible to diagnose varying degrees of Alzheimer’s through Magnetic Resonance Imaging. Analysis of the spatial overlap of non-heme iron, phosphorylated tau protein, and Amyloid Beta depositions in consecutive tissue slices of the hippocampus of post-mortem subjects ultimately facilitated characterization and detection of diseases, such as Alzheimer’s through MRI’s.

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Three-Dimensional Characterization And Mapping Of Gluteus Medius Muscle Fibers, Kylen Zibetti, Dr. Jonathan Wisco Sep 2013

Three-Dimensional Characterization And Mapping Of Gluteus Medius Muscle Fibers, Kylen Zibetti, Dr. Jonathan Wisco

Journal of Undergraduate Research

The human body is amazingly complex. Every structure and function affects multiple other structures and functions in a very automated way. Going from sitting to standing includes thousands of activated neurons, millions of contracting muscle fibers, and perfect balance coordinated between the semicircular canals and brain. With so much to study it was difficult to narrow it down. I decided though that I wanted to better understand anatomy, and especially the very fine anatomy of the hip because I am interested in gait pattern. After working with Dr. Wisco, I concluded that I would create a three dimensional model of …

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