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2011

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Articles 31 - 60 of 211

Full-Text Articles in Physiology

Two Days, Two Marathons: Superman?, Marco Vescovi M.D., Serena Benzo M.D., Daniele Bronzini, Flavia Bruttini M.D., Antonio Mortara, Ioanna Nakou M.D., Monica Vescovi M.D. Nov 2011

Two Days, Two Marathons: Superman?, Marco Vescovi M.D., Serena Benzo M.D., Daniele Bronzini, Flavia Bruttini M.D., Antonio Mortara, Ioanna Nakou M.D., Monica Vescovi M.D.

International Journal of Exercise Science: Conference Proceedings

The river marathon races are characterized by a duration longer than two hours, with intermissions at predetermined distances depending on the route. In these intermissions the athletes make portages where the competitors carry their canoes in a foot race with a distance of about 150 meters, and then they resumes paddling.

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The Effect Of Preparatory Arousal On Hand Grip Strength And 50 Metre Freestyle Swim Performance., Lewan Parker, Rebecca M. Sealey, Anne Swinbourne Nov 2011

The Effect Of Preparatory Arousal On Hand Grip Strength And 50 Metre Freestyle Swim Performance., Lewan Parker, Rebecca M. Sealey, Anne Swinbourne

International Journal of Exercise Science: Conference Proceedings

Preparatory arousal is a strategy in which an individual purposefully engages in an activity to get themselves emotionally “pumped up” or “charged up” to increase the body’s level of arousal [1]. Preparatory arousal is a common mental preparation strategy used among competitive athletes [2]. It is suggested that preparatory arousal can increase performance of simple tasks requiring maximal strength and muscular endurance and power [3]. However, the majority of preparatory arousal research has only examined non sport specific skills and thus the findings may not be transferable to actual sports that require more complex and dynamic movement patterns. With the …

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C-Reactive Protein And The Disease Analog Model May Identify Predisposed Pre-Obese African-American Women, James W. Navalta, Scott Lyons, Sharon E. Whitlock, Demetrice D. Kirkwood, Scott W. Arnett, Mark A. Schafer Nov 2011

C-Reactive Protein And The Disease Analog Model May Identify Predisposed Pre-Obese African-American Women, James W. Navalta, Scott Lyons, Sharon E. Whitlock, Demetrice D. Kirkwood, Scott W. Arnett, Mark A. Schafer

International Journal of Exercise Science: Conference Proceedings

While the obesity rate in the Unites States has been reported to have hit a plateau, the overall percentage of obese Americans remains alarmingly high (27% self-reported, 33% population estimate). While the subgroup with the highest 2010 obesity rate is Black, non-Hispanic women (41.9%), there remains a disparity in the research with regards to this population group. The implication of an elevated obese population puts a strain on health care, overall quality of life, and is associated with a number of other co-morbidities. Given this background, pilot work to evaluate a disease analog model for obesity would be useful with …

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Building Kayak Excellence: From The Adolescent To The Elite Athlete., Marco Vescovi M.D., Daniele Bronzini, Flavia Bruttini M.D., Antonio Mortara, Ioanna Nakou M.D. Nov 2011

Building Kayak Excellence: From The Adolescent To The Elite Athlete., Marco Vescovi M.D., Daniele Bronzini, Flavia Bruttini M.D., Antonio Mortara, Ioanna Nakou M.D.

International Journal of Exercise Science: Conference Proceedings

Building an athlete in order to reach his maximum possible performance is a long process which starts from infancy. The history of our interdisciplinary group ( medical doctors-trainers) is equally long. It started in the 80s with the cooperation of a medical doctor and a trainer. Over the years, the group has grown involving new trainers, former athletes, athletes and young doctors who share their own specific knowledge in order to individualize and promote the maximal performance of each single athlete, trying to keep them in optimal health and prevent typical injuries caused by overload.

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The Effect Of Fatigue On Shoulder Muscle Strength Ratios In Collegiate Water Polo Players, Bobby Sanders, Steven A. Hawkins, Michele Leblanc Nov 2011

The Effect Of Fatigue On Shoulder Muscle Strength Ratios In Collegiate Water Polo Players, Bobby Sanders, Steven A. Hawkins, Michele Leblanc

International Journal of Exercise Science: Conference Proceedings

Introduction: A proposed mechanism of shoulder injuries is imbalances in the strength of the shoulder muscles, however, the effects of fatigue on these imbalances are unknown. The purpose of this study was to investigate the relationship of isokinetic-induced fatigue on the development of shoulder muscle imbalances using both the conventional and functional ratio.

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Effect Of Ankle Taping And Bracing On Dynamic Balance And Perception Of Stability, William Gear, Jessica Bookhout, Amanda Solyntjes Nov 2011

Effect Of Ankle Taping And Bracing On Dynamic Balance And Perception Of Stability, William Gear, Jessica Bookhout, Amanda Solyntjes

International Journal of Exercise Science: Conference Proceedings

Ankle injuries are the most common injury associated with sports participation. A recent study examining NCAA injury data found that 14.9% of all injuries sustained in 15 intercollegiate sports were injuries to the ankle. Taping and bracing are commonly used measures to prevent and/or protect the ankle from injury. Patients often report a feeling of increased stability due to tape and/or brace, however previous studies examining the effect of ankle appliances on stability have produced conflicting results. The purpose of this study was to examine the effect of taping and bracing on dynamic stability, and the perception of stability with …

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Effect Of Increasing Levels Of Fatigue On Knee Proprioception, William Gear Nov 2011

Effect Of Increasing Levels Of Fatigue On Knee Proprioception, William Gear

International Journal of Exercise Science: Conference Proceedings

Ligament injuries of the knee, particularly the anterior cruciate ligament (ACL), represent a significant percentage of lower extremity injuries during athletic participation. One possible factor associate with the high percentage of knee ligament injuries is a decrease in proprioception associated with fatigue. Previous research has found a decrease in proprioception following maximal fatigue of the knee musculature and following low intensity work to maximum fatigue. To date no investigation has examined if incremental increases in fatigue have an effect on proprioception. Therefore, the purpose of this study was to examine the effect of increasing levels of fatigue on active joint …

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Blood Volume Unloading Reduces Cerebral Blood Flow, Taylor Drury, Darren Warburton, Aaron Phillips, Shannon Bredin Nov 2011

Blood Volume Unloading Reduces Cerebral Blood Flow, Taylor Drury, Darren Warburton, Aaron Phillips, Shannon Bredin

International Journal of Exercise Science: Conference Proceedings

Introduction: Cerebral autoregulation (CA) has been understood for over 50 years to maintain constant cerebral blood flow (CBF) over a wide range of arterial blood pressures (60-150 mmHg), and blood volumes. The original work, which published this relationship, however, was derived from a limited number of studies focused primarily on clinical populations. Since that time, it has been applied to healthy individuals and is a mainstay of almost all physiology textbooks. Recent evidence, however, has suggested that CBF in healthy individuals is not independent of alterations in blood pressure and volume, indicating a possible absence of cerebral autoregulation. Lower body …

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Harvest Of The Ipsilateral Hamstrings Does Not Result In Tibial Internal Rotation Strength And Endurance Insufficiencies For Patients 12 To 36 Months Post-Anterior Cruciate Ligament Reconstruction, Giampietro L. Vairo Nov 2011

Harvest Of The Ipsilateral Hamstrings Does Not Result In Tibial Internal Rotation Strength And Endurance Insufficiencies For Patients 12 To 36 Months Post-Anterior Cruciate Ligament Reconstruction, Giampietro L. Vairo

International Journal of Exercise Science: Conference Proceedings

Ipsilateral hamstrings tendons harvest as a primary autograft for anterior cruciate ligament (ACL) reconstruction has become increasingly prevalent among orthopaedic surgeons. Though, limited evidence exists detailing ensuing knee joint performance capacity. Previous authors have reported that ipsilateral semitendinosus and gracilis (STG) harvest results in significant tibial internal rotation strength deficiencies for related patients (1,2). However, prior data in regards to this measure have been reported as absolute as opposed to relative indices of strength and have not produced endurance results. Therefore, our objective was to profile relative tibial internal rotation strength and endurance responses to STG harvest in ACL reconstructed …

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The Metabolic Cost Of A Commercialized Video Fitness Program, Michele Olson Nov 2011

The Metabolic Cost Of A Commercialized Video Fitness Program, Michele Olson

International Journal of Exercise Science: Conference Proceedings

INTRODUCTION: Numerous fitness products and programs are promoted in mainstream society to the general public for the purposes of developing various aspects of physical fitness especially weight loss. However, there is often little information regarding these products and programs including the energy, or, caloric cost of the workout(s). Therefore, the purpose of this study was to determine the mean energy cost of a popular commercialized video exercise program titled, “The FIRM Express.”

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Keynote And Symposia Titles Nov 2011

Keynote And Symposia Titles

International Journal of Exercise Science: Conference Proceedings

Keynote and Symposia titles for the 2nd International eConference on Kinesiology and Integrated Physiology. Meeting was held between October 3-14, 2011 and can be found at: http://kinesiology.econferenceintl.com

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Age-Associated Disruption Of Molecular Clock Expression In Skeletal Muscle Of The Spontaneously Hypertensive Rat, Mitsunori Miyazaki, Elizabeth Schroder, Stephanie E. Edelmann, Michael E. Hughes, Karl Kornacker, C. William Balke, Karyn A. Esser Nov 2011

Age-Associated Disruption Of Molecular Clock Expression In Skeletal Muscle Of The Spontaneously Hypertensive Rat, Mitsunori Miyazaki, Elizabeth Schroder, Stephanie E. Edelmann, Michael E. Hughes, Karl Kornacker, C. William Balke, Karyn A. Esser

Physiology Faculty Publications

It is well known that spontaneously hypertensive rats (SHR) develop muscle pathologies with hypertension and heart failure, though the mechanism remains poorly understood. Woon et al. (2007) linked the circadian clock gene Bmal1 to hypertension and metabolic dysfunction in the SHR. Building on these findings, we compared the expression pattern of several core-clock genes in the gastrocnemius muscle of aged SHR (80 weeks; overt heart failure) compared to aged-matched control WKY strain. Heart failure was associated with marked effects on the expression of Bmal1, Clock and Rora in addition to several non-circadian genes important in regulating skeletal muscle phenotype including …

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The Effect Of Exercise Mode And Intensity Of Submaximal Physical Activities On Salivary Testosterone To Cortisol Ratio And Α-Amylase In Young Active Males, Mohammad Ali Azarbayjani, Hoseyn Fatolahi, Mohammad Javad Rasaee, Maghsod Peeri, Roholah Babaei Oct 2011

The Effect Of Exercise Mode And Intensity Of Submaximal Physical Activities On Salivary Testosterone To Cortisol Ratio And Α-Amylase In Young Active Males, Mohammad Ali Azarbayjani, Hoseyn Fatolahi, Mohammad Javad Rasaee, Maghsod Peeri, Roholah Babaei

International Journal of Exercise Science

We examined the effect of exercise intensity and mode on the acute responses of free testosterone to cortisol ratio and salivary α-amylase. We also evaluated the relationship between cortisol and salivary α-amylase. Ten healthy young active males participated voluntarily in this study in six single sessions. They exercised on a cycle ergo meter, treadmill, and elliptical instrument at intensities of 70% and 85% maximum heart rate for 25 minutes. Saliva samples were collected 5 minutes before and 5 minutes after each exercise session. No significant changes were observed for cortisol. Free testosterone to cortisol ratio increased during each exercise session …

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Influence Of Differences In Exercise-Intensity And Kilograms/Set On Energy Expenditure During And After Maximally Explosive Resistance Exercise, Scott A. Mazzetti Ph.D., Christopher Wolff, Brittany Collins, Michael T. Kolankowski, Brittany Wilkerson, Matthew Overstreet, Troy Grube Oct 2011

Influence Of Differences In Exercise-Intensity And Kilograms/Set On Energy Expenditure During And After Maximally Explosive Resistance Exercise, Scott A. Mazzetti Ph.D., Christopher Wolff, Brittany Collins, Michael T. Kolankowski, Brittany Wilkerson, Matthew Overstreet, Troy Grube

International Journal of Exercise Science

With resistance exercise, greater intensity typically elicits increased energy expenditure, but heavier loads require that the lifter perform more sets of fewer repetitions, which alters the kilograms lifted per set. Thus, the effect of exercise-intensity on energy expenditure has yielded varying results, especially with explosive resistance exercise. This study was designed to examine the effect of exercise-intensity and kilograms/set on energy expenditure during explosive resistance exercise. Ten resistance-trained men (22±3.6 years; 84±6.4 kg, 180±5.1 cm, and 13±3.8 %fat) performed squat and bench press protocols once/week using different exercise-intensities including 48% (LIGHT-48), 60% (MODERATE-60), and 72% of 1-repetition-maximum (1-RM) (HEAVY-72), plus …

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Impact Of Exercise Partner Attractiveness On Mood, Enjoyment, And Exertion, Thomas G. Plante, Sarah Gregg, Jaclyn Rubbo, Thomas Favero, Ashley Morisako, Jessica Cuadra Oct 2011

Impact Of Exercise Partner Attractiveness On Mood, Enjoyment, And Exertion, Thomas G. Plante, Sarah Gregg, Jaclyn Rubbo, Thomas Favero, Ashley Morisako, Jessica Cuadra

International Journal of Exercise Science

Social comparison theory was used to examine if males exercising with a female research confederate posing as either attractive or unattractive would alter their exercise mood, exertion, and enjoyment. A total of 101 college students (51 males and 51 females) were randomly assigned to one of three conditions: biking alone, biking with an attractive female confederate, or biking with the same female confederate appearing unattractive. All participants were instructed to complete 20 minutes of exercise at 60%-70% of their maximum target heart rate. Standard exercise mood measures (e.g., Activation-Deactivation Adjective Check List) were administered immediately prior to and immediately following …

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Do Exergames Allow Children To Achieve Physical Activity Intensity Commensurate With National Guidelines?, Rachel Perron, Courtney Graham, Jamie Feldman, Rebecca Moffett, Eric E. Hall Oct 2011

Do Exergames Allow Children To Achieve Physical Activity Intensity Commensurate With National Guidelines?, Rachel Perron, Courtney Graham, Jamie Feldman, Rebecca Moffett, Eric E. Hall

International Journal of Exercise Science

The purpose of this study was to determine if two popular exergames, Wii Fit™ and EA Sports Active™, both games for the Nintendo Wii™ console, help children achieve intensity consistent with recommended physical activity guidelines. Thirty children (19 males and 11 females, Mean age = 9.4 ± 1.8 years) participated in this study by playing each game during one research session. During the session participants wore a heart rate monitor and accelerometer to measure exercise intensity. Perceived exertion (RPE) was measured with the children’s run/walk OMNI scale. All three measures of exercise intensity (heart rate, accelerometer counts, and RPE) found …

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Oxidative Stress Response To Short Duration Bout Of Submaximal Aerobic Exercise In Healthy Young Adults, Keith M. Diaz, Deborah L. Feairheller Phd, Kathleen M. Sturgeon, Sheara T. Williamson, Michael D. Brown Oct 2011

Oxidative Stress Response To Short Duration Bout Of Submaximal Aerobic Exercise In Healthy Young Adults, Keith M. Diaz, Deborah L. Feairheller Phd, Kathleen M. Sturgeon, Sheara T. Williamson, Michael D. Brown

International Journal of Exercise Science

The purpose of this study was to investigate the oxidative stress response to a short duration bout of submaximal exercise in a cohort of healthy young adults. 15 apparently healthy college age males and females completed a modified Bruce-protocol treadmill test to 75-80% of their heart rate reserve. Blood samples collected immediately before (pre-exercise), immediately after, 30, 60 and 120 minutes post-exercise were assayed for total antioxidant capacity (TAC), superoxide disumutase (SOD), thiobarbituric acid-reactive substances (TBARS), and protein carbonyls (PC). SOD activity was significantly increased from pre-exercise levels at 30 minutes (77%), 60 minutes (33%), and 120 minutes (37%) post-exercise. …

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The Relationship Between Stride Rates, Lengths And Body Size And Their Affect On Elite Triathletes’ Running Performance During Competition, Grant J. Landers, Brian A. Blanksby, Timothy R. Ackland Oct 2011

The Relationship Between Stride Rates, Lengths And Body Size And Their Affect On Elite Triathletes’ Running Performance During Competition, Grant J. Landers, Brian A. Blanksby, Timothy R. Ackland

International Journal of Exercise Science

Previous research has suggested that a degree of predictability exists in the relationship between self-selected running stride rates (SR) and stride lengths (SL) with measures of body size such as mass, height and limb lengths. Significant correlations have also been revealed between these body size measures and performance and between SL and performance. However, there is also evidence to suggest that triathlon performance may be related to maintaining a longer SL during the final run. Hence, the aim of this investigation was to examine whether there was any relationship between SR and SL, with body masses and heights of senior …

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Repeated Sprint Performance In Male And Female College Athletes Matched For Vo2max Relative To Fat Free Mass, Amanda L. Mageean, Ryan P. Alexander, Constance M. Mier Oct 2011

Repeated Sprint Performance In Male And Female College Athletes Matched For Vo2max Relative To Fat Free Mass, Amanda L. Mageean, Ryan P. Alexander, Constance M. Mier

International Journal of Exercise Science

The purpose of this study was to examine gender differences in repeated sprint exercise (RSE) performance among male and female athletes matched for VO2max relative to FFM (VO2max FFM). Thirty nine male and female college athletes performed a graded exercise test for VO2max and hydrostatic weighing to determine FFM. From the results, 11 pairs of males and females matched for VO2max FFM (mean ± SD; 58.3 ± 4.3 and 58.9 ± 4.6 ml.kg FFM-1.min-1; men and women, respectively) were identified. On a separate day, matched participants performed a RSE protocol that consisted of five 6-sec cycle sprints with 30-sec recovery …

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Outcomes Of A Family Based Pediatric Obesity Program - Preliminary Results, Meghan L. Ruebel, Kate A. Heelan, R.Todd Bartee, Nancy Foster Oct 2011

Outcomes Of A Family Based Pediatric Obesity Program - Preliminary Results, Meghan L. Ruebel, Kate A. Heelan, R.Todd Bartee, Nancy Foster

International Journal of Exercise Science

Children that are classified as obese (body mass index (BMI) > 95th percentile for age and sex, Centers for Disease Control and Prevention) have an increased risk for metabolic and cardiovascular complications. Family based programs that focus on physical activity (PA) and healthy eating are recommended for treatment of pediatric obesity. The purpose of the current study is to determine the outcomes of Building Healthy Families (BHF), a family-based pediatric weight loss treatment program composed of nutrition, physical activity and behavioral modification strategies. In addition, mediating variables that are associated with weight loss in children, in order to enhance the retention …

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Case Study On The Development Of The International Journal Of Exercise Science, Scott Lyons Oct 2011

Case Study On The Development Of The International Journal Of Exercise Science, Scott Lyons

International Journal of Exercise Science

The International Journal of Exercise Science is a quarterly, online, open access publication dedicated to the dissemination of research in the areas of Exercise Science, Exercise Physiology, Human Performance, Kinesiology, and related disciplines. Dr. James W. Navalta and Dr. T. Scott Lyons (the author), both Associate Professors of Exercise Science at Western Kentucky University, are the founders of the International Journal of Exercise Science (IJES). IJES is a student-focused journal, in that the editors are specifically seeking research that is led by graduate or undergraduate students. Manuscripts submitted by professionals (defined as those holding a terminal degree) are also gladly …

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A Lipid-Anchored Snare Supports Membrane Fusion, Hao Xu, Michael Zick, William T. Wickner, Youngsoo Jun Oct 2011

A Lipid-Anchored Snare Supports Membrane Fusion, Hao Xu, Michael Zick, William T. Wickner, Youngsoo Jun

Dartmouth Scholarship

Intracellular membrane fusion requires R-SNAREs and Q-SNAREs to assemble into a four-helical parallel coiled-coil, with their hydrophobic anchors spanning the two apposed membranes. Based on the fusion properties of chemically defined SNARE- proteoliposomes, it has been proposed that the assembly of this helical bundle transduces force through the entire bilayer via the transmembrane SNARE anchor domains to drive fusion. However, an R-SNARE, Nyv1p, with a genetically engineered lipid anchor that spans half of the bilayer suffices for the fusion of isolated vacuoles, although this organelle has other R-SNAREs. To demonstrate unequivocally the fusion activity of lipid-anchored Nyv1p, we reconstituted proteoliposomes …

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A Mathematical Model Of Muscle Containing Heterogeneous Half-Sarcomeres Exhibits Residual Force Enhancement, Stuart G. Campbell, P. Chris Hatfield, Kenneth S. Campbell Sep 2011

A Mathematical Model Of Muscle Containing Heterogeneous Half-Sarcomeres Exhibits Residual Force Enhancement, Stuart G. Campbell, P. Chris Hatfield, Kenneth S. Campbell

Physiology Faculty Publications

A skeletal muscle fiber that is stimulated to contract and then stretched from L₁ to L₂ produces more force after the initial transient decays than if it is stimulated at L₂. This behavior has been well studied experimentally, and is known as residual force enhancement. The underlying mechanism remains controversial. We hypothesized that residual force enhancement could reflect mechanical interactions between heterogeneous half-sarcomeres. To test this hypothesis, we subjected a computational model of interacting heterogeneous half-sarcomeres to the same activation and stretch protocols that produce residual force enhancement in real preparations. Following a transient period of elevated force associated with …

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Functional Plasticity Of Central Trpv1 Receptors In Brainstem Dorsal Vagal Complex Circuits Of Streptozotocin-Treated Hyperglycemic Mice, Andrea Zsombok, Muthu D. Bhaskaran, Hong Gao, Andrei V. Derbenev, Bret N. Smith Sep 2011

Functional Plasticity Of Central Trpv1 Receptors In Brainstem Dorsal Vagal Complex Circuits Of Streptozotocin-Treated Hyperglycemic Mice, Andrea Zsombok, Muthu D. Bhaskaran, Hong Gao, Andrei V. Derbenev, Bret N. Smith

Physiology Faculty Publications

Emerging data indicate that central neurons participate in diabetic processes by modulating autonomic output from neurons in the dorsal motor nucleus of the vagus (DMV). We tested the hypothesis that synaptic modulation by transient receptor potential vanilloid type 1 (TRPV1) receptors is reduced in the DMV in slices from a murine model of type 1 diabetes. The TRPV1 agonist capsaicin robustly enhanced glutamate release onto DMV neurons by acting at preterminal receptors in slices from intact mice, but failed to do so in slices from diabetic mice. TRPV1 receptor protein expression in the vagal complex was unaltered. Brief insulin preapplication …

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Beta-Lysine Discrimination By Lysyl-Trna Synthetase, Marla S. Gilreath, Hervé Roy, Tammy J. Bullwinkle, Assaf Katz, Michael Ibba, William Wiley Navarre Sep 2011

Beta-Lysine Discrimination By Lysyl-Trna Synthetase, Marla S. Gilreath, Hervé Roy, Tammy J. Bullwinkle, Assaf Katz, Michael Ibba, William Wiley Navarre

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Elongation factor P is modified with (R)‐β‐lysine by the lysyl‐tRNA synthetase (LysRS) paralog PoxA. PoxA specificity is orthogonal to LysRS, despite their high similarity. To investigate α‐ and β‐lysine recognition by LysRS and PoxA, amino acid replacements were made in the LysRS active site guided by the PoxA structure. A233S LysRS behaved as wild type with α‐lysine, while the G469A and A233S/G469A variants decreased stable α‐lysyl‐adenylate formation. A233S LysRS recognized β‐lysine better than wildtype, suggesting a role for this residue in discriminating α‐ and β‐amino acids. Both enantiomers of β‐lysine were substrates for tRNA aminoacylation by LysRS, which, together with …

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Load Carriage Distance Run And Pushups Tests: No Body Mass Bias And Occupationally Relevant, Paul M. Vanderburgh, Nicholas S. Mickley, Philip A. Anloague, Kimber Lucius Sep 2011

Load Carriage Distance Run And Pushups Tests: No Body Mass Bias And Occupationally Relevant, Paul M. Vanderburgh, Nicholas S. Mickley, Philip A. Anloague, Kimber Lucius

Health and Sport Science Faculty Publications

Recent research has demonstrated body mass (M) bias in military physical fi tness tests favoring lighter, not just leaner, service members. Mathematical modeling predicts that a distance run carrying a backpack of 30 lbs would eliminate M-bias. The purpose of this study was to empirically test this prediction for the U.S. Army push-ups and 2-mile run tests. Two tests were performed for both events for each of 56 university Reserve Offi cer Training Corps male cadets: with (loaded) and without backpack (unloaded). Results indicated signifi cant M-bias in the unloaded and no M-bias in the loaded condition for both events. …

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Aging And Sympathetic Neurotransmission In Two Strains Of Rats That Differ In Longevity And Immune Profiles, Sam David Perez Sep 2011

Aging And Sympathetic Neurotransmission In Two Strains Of Rats That Differ In Longevity And Immune Profiles, Sam David Perez

Loma Linda University Electronic Theses, Dissertations & Projects

Age-related changes in sympathetic neurotransmission in immune organs may be associated with immunosenescence; however no causal relationship has been established. From previous studies in Fischer rats (F344), we have found that during middle age, sympathetic nerve activity (SNA) rises in the spleen followed by a decline in noradrenergic (NA) innervation. Also, increased sympathetic signaling via betaadrenergic receptor (β-AR) and reduced proliferation of lymphocytes are evident with increasing age. Although SNA progressively rises with age, effects of age on sympathetic factors may be different across rat strains. If causal relationships exist between sympathetic activity and immune function, they may be related …

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First Transcriptome Of The Testis-Vas Deferens-Male Accessory Gland And Proteome Of The Spermatophore From Dermacentor Variabilis (Acari: Ixodidae), Daniel E. Sonenshine, Brooke W. Bissinger, Noble Egekwu, Kevin V. Donohue, Sayed M. Khalil, R. Michael Roe Sep 2011

First Transcriptome Of The Testis-Vas Deferens-Male Accessory Gland And Proteome Of The Spermatophore From Dermacentor Variabilis (Acari: Ixodidae), Daniel E. Sonenshine, Brooke W. Bissinger, Noble Egekwu, Kevin V. Donohue, Sayed M. Khalil, R. Michael Roe

Biological Sciences Faculty Publications

Ticks are important vectors of numerous human diseases and animal diseases. Feeding stimulates spermatogenesis, mating and insemination of male factors that trigger female reproduction. The physiology of male reproduction and its regulation of female development are essentially a black box. Several transcriptomes have catalogued expression of tick genes in the salivary glands, synganglion and midgut but no comprehensive investigation has addressed male reproduction and mating. Consequently, a new global approach using transcriptomics, proteomics, and quantitative gene expression is needed to understand male reproduction and stimulation of female reproduction.This first transcriptome to the reproductive biology of fed male ticks, Dermacentor variabilis …

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Impaired Resistance Artery Reactivity Following Arteriogenesis, Michael (Mike) Machado Sep 2011

Impaired Resistance Artery Reactivity Following Arteriogenesis, Michael (Mike) Machado

Biomedical Engineering

No abstract provided.

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Spiking Patterns And Their Functional Implications In The Antennal Lobe Of The Tobacco Hornworm Manduca Sexta, Hong Lei, Carolina E. Reisenman, Caroline H. Wilson, Prasad Gabbur, John G. Hildebrand Aug 2011

Spiking Patterns And Their Functional Implications In The Antennal Lobe Of The Tobacco Hornworm Manduca Sexta, Hong Lei, Carolina E. Reisenman, Caroline H. Wilson, Prasad Gabbur, John G. Hildebrand

Health Sciences and Kinesiology Faculty Articles

Bursting as well as tonic firing patterns have been described in various sensory systems. In the olfactory system, spontaneous bursts have been observed in neurons distributed across several synaptic levels, from the periphery, to the olfactory bulb (OB) and to the olfactory cortex. Several in vitro studies indicate that spontaneous firing patterns may be viewed as “fingerprints” of different types of neurons that exhibit distinct functions in the OB. It is still not known, however, if and how neuronal burstiness is correlated with the coding of natural olfactory stimuli. We thus conducted an in vivo study to probe this question …

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