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Articles 91 - 117 of 117
Full-Text Articles in Physiology
Ischemia Impairs Vasodilation In Skeletal Muscle Resistance Artery, Kyle Remington Struthers
Ischemia Impairs Vasodilation In Skeletal Muscle Resistance Artery, Kyle Remington Struthers
Master's Theses
Functional vasodilation in arterioles is impaired with chronic ischemia. We sought to examine the impact of chronic ischemia and age on skeletal muscle resistance artery function. To examine the impact of chronic ischemia, the femoral artery was resected from young (2-3mo) and adult (6-7mo) mice and the profunda femoris artery diameter was measured at rest and following gracilis muscle contraction 14 days later using intravital microscopy. Functional vasodilation was significantly impaired in ischemic mice (14.4±4.6% vs. 137.8±14.3%, p<0.0001 n=8) and non-ischemic adult mice (103.0±9.4% vs. 137.8±14.3%, p=0.05 n=10). In order to analyze the cellular mechanisms of the impairment, a protocol was developed to apply pharmacological agents to the experimental preparation while maintaining tissue homeostasis. Endothelial and smooth muscle dependent vasodilation were impaired with ischemia, 39.6 ± 13.6% vs. 80.5 ± 11.4% and 43.0 ± 11.7% vs. 85.1 ± 10.5%, respectively. From this data, it can be supported that smooth muscle dysfunction is the reason for the observed impairment in arterial vasodilation.
Modulation Of Hypoglossal Motoneurons By Nitric Oxide, Justin Philip Benoit
Modulation Of Hypoglossal Motoneurons By Nitric Oxide, Justin Philip Benoit
Master's Theses
Obstructive sleep apnea (OSA)- the occurrence of repetitive episodes of airway obstruction during sleep- is considered a major health problem affecting up to 9% of adults in the United States (Parish & Somers, 2004). The hypoglossal motor nucleus (HMN) controls genioglossus muscle tone and is critically important for maintaining airway patency; loss of excitatory input to the HMN during sleep results in disfacilitation of hypoglossal motoneurons, increased airway resistance and contributes to the development of OSA (Horner R. L., 2007). However, a fundamental question of sleep medicine that remains unresolved is what mechanisms help maintain airway patency during sleep? A …
The Role Of T-Type Calcium Channels In Vascular Smooth Muscle Cell Cycle Regulation, Abigail Prier
The Role Of T-Type Calcium Channels In Vascular Smooth Muscle Cell Cycle Regulation, Abigail Prier
Master's Theses
Results from previous experiments have provided evidence for T-type channel expression in adult pulmonary artery smooth muscle cells (PASMCs) using electrophysiology and qRT-PCR. Studies have also shown that when T-type channels are blocked, either pharmacological or with small hairpin RNA targeted against T-type channel Cav3.1 subunit, mRNA levels are reduced and cell proliferation is inhibited. These results suggest a connection between T-type calcium channels and cell proliferation. In this thesis, Cav3.1 and its possible interplay with cyclin D, an early marker of the cell cycle, was investigated. The time course of cyclin D's translocation to the nucleus to begin the …
Acute Nitrate Exposure Causes Proteomic Changes Consistent With The Regulation Of Reactive Oxygen And Nitrogen Species, Lauren R. Hitt, Lars Tomanek
Acute Nitrate Exposure Causes Proteomic Changes Consistent With The Regulation Of Reactive Oxygen And Nitrogen Species, Lauren R. Hitt, Lars Tomanek
Master's Theses
Nitrate is the most common ionic form of nitrogen in aquatic ecosystems. Although nitrate is known to affect ecosystems at high levels through eutrophication, hypoxia and loss of biodiversity, it is considered to be physiologically inert to the individual aquatic organism. To test the physiological effects of nitrate on aquatic life, we exposed gill tissue of the Pacific oyster, Crassostrea gigas, to nitrate and characterized changes in protein expression, using a gel-based proteomics approach. Of the 642 protein spots detected, we found that 24 proteins (15 identified) changed expression in response to a 6-hour exposure to nitrate concentrations ranging from …
The Relationship Between Plasma Steroid Hormone Concentrations And The Reproductive Cycle Of The Northern Pacific Rattlesnake, Crotalus Oreganus, Craig Michael Lind
The Relationship Between Plasma Steroid Hormone Concentrations And The Reproductive Cycle Of The Northern Pacific Rattlesnake, Crotalus Oreganus, Craig Michael Lind
Master's Theses
To gain a better understanding of the role of steroid hormones in vertebrate reproduction, we quantified steroid hormone concentrations in a free ranging population of the Northern Pacific rattlesnake, Crotalus oreganus. Plasma steroid hormone concentrations were quantified for both male and female snakes throughout the active season (Mar-Oct). We measured testosterone (T), 5α-dihydrotestosterone (DHT), and corticosterone (B) concentrations in male and female snakes. 17β-estradiol (E2) and progesterone (P) were measured in females only. We also observed breeding behaviors (e.g. consortship, courtship, and copulation) in the field and measured testis and follicle size in male and female snakes from museum collections. …
Relationship Between Intracellular Ph And Calcium Uptake In The Skeletal Muscle During Sepsis, Gin Mo
Relationship Between Intracellular Ph And Calcium Uptake In The Skeletal Muscle During Sepsis, Gin Mo
Master's Theses
No abstract provided.
The Magnetic Separation Of Rat Anterior Pituitary Cells, Jodi Flaws
The Magnetic Separation Of Rat Anterior Pituitary Cells, Jodi Flaws
Master's Theses
No abstract provided.
Dromotropic Influences Of The Individual Cardiac Nerves At The Atrioventricular Junction Of The Canine Heart, Lynn E. Rinkema
Dromotropic Influences Of The Individual Cardiac Nerves At The Atrioventricular Junction Of The Canine Heart, Lynn E. Rinkema
Master's Theses
No abstract provided.
The Effect Of Daily Exercise On Regional Myocardial Flow Of Proximal Coronary Constriction Dogs And Its Mechanism, Ming Hsiung Hwang
The Effect Of Daily Exercise On Regional Myocardial Flow Of Proximal Coronary Constriction Dogs And Its Mechanism, Ming Hsiung Hwang
Master's Theses
No abstract provided.
Variations In Mood During The Menstrual Cycle In Relation To The Personality Factors Of Trait-Anxiety And Androgyny, Mary Leslie Smith O'Connor
Variations In Mood During The Menstrual Cycle In Relation To The Personality Factors Of Trait-Anxiety And Androgyny, Mary Leslie Smith O'Connor
Master's Theses
No abstract provided.
The Effects Of Left Stellate Ganglion And Ventrolateral Cardiac Nerve Activity On Canine Av Nodal Electrophysiologic Properties, David Leon Fishman
The Effects Of Left Stellate Ganglion And Ventrolateral Cardiac Nerve Activity On Canine Av Nodal Electrophysiologic Properties, David Leon Fishman
Master's Theses
No abstract provided.
Insulin And Altered Reticuloendothelial System Function, Angela M. Hadbavny
Insulin And Altered Reticuloendothelial System Function, Angela M. Hadbavny
Master's Theses
No abstract provided.
Myocardial And Splenic Catecholamine Alterations In Burn Shock, Reno R. Cova
Myocardial And Splenic Catecholamine Alterations In Burn Shock, Reno R. Cova
Master's Theses
No abstract provided.
Relative Densities Of Sympathetic Nerve Terminals In Dog Right Atrium, Caryl Jean Coglianese
Relative Densities Of Sympathetic Nerve Terminals In Dog Right Atrium, Caryl Jean Coglianese
Master's Theses
No abstract provided.
Effects Of Diethylstilbestrol, Norethindrone, And Mestranol On Selected Microbes, John N. Haan
Effects Of Diethylstilbestrol, Norethindrone, And Mestranol On Selected Microbes, John N. Haan
Master's Theses
No abstract provided.
The Effects Of Left Stellate Ganglion Stimulation On Left Ventricular Synchrony In Dogs, Charles Edward Osadjan
The Effects Of Left Stellate Ganglion Stimulation On Left Ventricular Synchrony In Dogs, Charles Edward Osadjan
Master's Theses
No abstract provided.
Mechanism Of Hypotension In Acute Spinal Shock, John Francis Moran
Mechanism Of Hypotension In Acute Spinal Shock, John Francis Moran
Master's Theses
No abstract provided.
Reflex Respiratory Effects From Intermittent Stimulation Of Vagus And Superior Laryngeal Nerves, Charles Hillenbrand
Reflex Respiratory Effects From Intermittent Stimulation Of Vagus And Superior Laryngeal Nerves, Charles Hillenbrand
Master's Theses
No abstract provided.
Some Actions Of Sodium Salicylate On Scorbutic Guinea Pigs, Jacob John Giardina
Some Actions Of Sodium Salicylate On Scorbutic Guinea Pigs, Jacob John Giardina
Master's Theses
No abstract provided.
Changes Of Electrical Resistance In Nerve During Block By Cold, Irvin Franklin Hummon Jr.
Changes Of Electrical Resistance In Nerve During Block By Cold, Irvin Franklin Hummon Jr.
Master's Theses
No abstract provided.
Further Studies Of The Effect Of Saponin On Intestinal Absorption, Nello Michael Felicelli
Further Studies Of The Effect Of Saponin On Intestinal Absorption, Nello Michael Felicelli
Master's Theses
No abstract provided.
Studies On The Intestinal Absorption Of Histamine. , Raphael William Albi
Studies On The Intestinal Absorption Of Histamine. , Raphael William Albi
Master's Theses
No abstract provided.
Studies On The Relation Between Inorganic Ions And Drugs Acting On The Excised Intestine, William Blasé Spiteri
Studies On The Relation Between Inorganic Ions And Drugs Acting On The Excised Intestine, William Blasé Spiteri
Master's Theses
No abstract provided.
Studies Of The Intestinal Absorption Of Tyramine, Charles Lewis Coyle
Studies Of The Intestinal Absorption Of Tyramine, Charles Lewis Coyle
Master's Theses
No abstract provided.
On The Sedimentation Of Erythrocytes From Lymph, John Russell
On The Sedimentation Of Erythrocytes From Lymph, John Russell
Master's Theses
No abstract provided.
The Influence Of Saponin On The Intestinal Absorption Of Calcium, Frank Charles Sternasty
The Influence Of Saponin On The Intestinal Absorption Of Calcium, Frank Charles Sternasty
Master's Theses
No abstract provided.
Studies On The Intestinal Absorption Of Histamine. I. The Effects Of Various Chemical Agents Applied To The Mucosa, Lambert Francis Mammoser
Studies On The Intestinal Absorption Of Histamine. I. The Effects Of Various Chemical Agents Applied To The Mucosa, Lambert Francis Mammoser
Master's Theses
No abstract provided.