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Full-Text Articles in Pharmacology, Toxicology and Environmental Health

Fluid Properties Of Solvents And Oils Used In In Situ Forming Microparticles, Sai Myo Thu Rein, Torsak Intaraphairot Jan 2022

Fluid Properties Of Solvents And Oils Used In In Situ Forming Microparticles, Sai Myo Thu Rein, Torsak Intaraphairot

The Thai Journal of Pharmaceutical Sciences

In situ forming microparticle (ISM) has been recently used as the injectable drug delivery system prepared from polymeric non-aqueous phase in oil emulsion. Solvents and oils used in ISM including N-methyl pyrrolidone (NMP), 2-pyrrolidone (PYR), dimethyl sulfoxide (DMSO), glycofurol, triacetin, olive oil, camellia oil and isopropyl myristate (IPM) were evaluated for pH, density, viscosity, flow time, surface tension, contact angle, color distribution, injectability, antimicrobial activities and cytotoxicity. The most viscous camellia oil and olive oil showed the highest flow time with lowest color diffusion and lower injectability; thus, they were suitable for performing as external phase of ISM to prolong …


Microbiological Study In A Gneissic Cave From Sri Lanka, With Special Focus On Potential Antimicrobial Activities, Ethige Isuru P. Silva, Pathmakumara Jayasingha, Saman Senanayake, Anura Dandeniya, Dona Helani Munasinghe Mar 2021

Microbiological Study In A Gneissic Cave From Sri Lanka, With Special Focus On Potential Antimicrobial Activities, Ethige Isuru P. Silva, Pathmakumara Jayasingha, Saman Senanayake, Anura Dandeniya, Dona Helani Munasinghe

International Journal of Speleology

The emergence of antibiotic resistance is a global health crisis, thus the search for novel antimicrobial compounds has become a continuous necessity. Underexplored and extreme environments, such as cave ecosystems, have been identified as a promising potential source for the discovery of novel microorganisms with novel antimicrobial compounds (AMC). This study presents the first cave microbiological investigation in Sri Lanka, with a special preference for bioprospecting of novel AMC. The cave sediment characterization demonstrated the presence of close to strong acidic conditions (pH 3.1 – 3.3) and thus indicates the possibility of isolating acidophilic microorganisms. Eight cave wall/ceiling fungal strains …


Antimicrobial Activities Of Medicinal Plant Products(ฤทธิ์ต้านจุลินทรีย์ของผลิตภัณฑ์สมุนไพร), Areerat Laorpaksa, Nongluksna Sriubolmas, Peerapun Khruddhaveacho Jan 2002

Antimicrobial Activities Of Medicinal Plant Products(ฤทธิ์ต้านจุลินทรีย์ของผลิตภัณฑ์สมุนไพร), Areerat Laorpaksa, Nongluksna Sriubolmas, Peerapun Khruddhaveacho

The Thai Journal of Pharmaceutical Sciences

This study determined antimicrobial activities of 57 selected medicinal plant products with antimicrobial indications by agar diffusion assay. The percentage of samples exhibiting antibacterial activities against Staphylococcus aureus ATCC 29213, Salmone...


Chemical Compositions And Antimicrobial Activities Of Essential Oil From Melaleuca Leucadendron Var. Minor(องค์ประกอบทางเคมีและฤทธิ์ต้านจุลินทรีย์ของน้ำมันห..., Puangnoi Lohakachornpan, Watcharin Rangsipanuratn Jan 2001

Chemical Compositions And Antimicrobial Activities Of Essential Oil From Melaleuca Leucadendron Var. Minor(องค์ประกอบทางเคมีและฤทธิ์ต้านจุลินทรีย์ของน้ำมันห..., Puangnoi Lohakachornpan, Watcharin Rangsipanuratn

The Thai Journal of Pharmaceutical Sciences

The fresh leaves of Melaleuca leucadendron Linn. var. minor Duthie (Myrtaceae) was hydrodistilled by Clevenger apparatus. Gas chromatography-mass spectrometry analyses revealed the presence of 45 components. Terpinolene (29.21 %), a-terpinene (22.55%), 2...