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Pharmacology, Toxicology and Environmental Health Commons

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2017

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Full-Text Articles in Pharmacology, Toxicology and Environmental Health

Justin's Save The Frogs Project, Justin Sather Dec 2017

Justin's Save The Frogs Project, Justin Sather

The STEAM Journal

Justin’s Save the Frog Project goals are 1) to spread the awareness about the rapid decline in frog population 2) inspire others to make the environment a better place for people and animals 3) make an impact by building wetlands in California specifically for the CA Red-Legged Frogs and Foothill Yellow Legged.


Autoethnography As An Instrument For Professional (Trans) Formation In Pharmaceutical Care Practice, Daniela Álvares Machado Silva, Simone Araújo Medina Mendonça, Maureen O´Dougherty, Djenane Ramalho De Oliveira, Clarice Chemello Nov 2017

Autoethnography As An Instrument For Professional (Trans) Formation In Pharmaceutical Care Practice, Daniela Álvares Machado Silva, Simone Araújo Medina Mendonça, Maureen O´Dougherty, Djenane Ramalho De Oliveira, Clarice Chemello

The Qualitative Report

The recent inclusion of pharmacists in primary healthcare in Brazil through the Family Health Support Team has encouraged them to reflect on the need to change from a professional focused on medications to one focused on individuals. This autoethnography allowed a pharmacist to confront her perspectives on clinical practice between 2014 and 2016, a period when she decided to challenge her traditional training as a pharmacist centered on medications. Using pharmaceutical care practice as the theoretical framework that prompted the profession of pharmacy to change its focus to the patient, the authors collaborated to construct a monologue that engages readers …


Investigating The Toxicity And Accumulation Of 2,4-Dichlorophenoxyacetic Acid (2,4-D) And Glyphosate In Eisenia Fetida, Caitlin Lazurick, Nicole Lidzbarski, Rachel Owings, Jeff Brotherton, Edna Steele Nov 2017

Investigating The Toxicity And Accumulation Of 2,4-Dichlorophenoxyacetic Acid (2,4-D) And Glyphosate In Eisenia Fetida, Caitlin Lazurick, Nicole Lidzbarski, Rachel Owings, Jeff Brotherton, Edna Steele

Journal of the South Carolina Academy of Science

Glyphosate, the main ingredient in Roundup®, is the most widely used herbicide in the world. It is also used in combination with another effective herbicide, 2,4-D, in the formulation called Enlist Duo®. The EPA approved the use of Enlist Duo® on certain crops including those genetically modified to be resistant to both herbicides. The predicted significant increase in the use of these herbicides raised concerns from the general public because both compounds have been classified as possibly or probably carcinogenic. Since herbicides are applied directly to vegetation, the safety of organisms that come in contact …


Phytochemical Screening And Determination Of Antibacterial, Anti-Tumorigenic And Dna Protection Ability Of Root Extracts Of Saussurea Lappa, Sughra Arif Minhas, Fida Muhammad Khan, Fakhar-I- Abbas, Abu Ul Hassan Faiz Sep 2017

Phytochemical Screening And Determination Of Antibacterial, Anti-Tumorigenic And Dna Protection Ability Of Root Extracts Of Saussurea Lappa, Sughra Arif Minhas, Fida Muhammad Khan, Fakhar-I- Abbas, Abu Ul Hassan Faiz

Journal of Bioresource Management

Saussurea lappa is a traditionally well-known plant for its medicinal uses in different indigenous systems of medicine. It is widely used in the treatment of asthma, ulcer, stomach problems and inflammatory diseases. In current study the phytochemical screening of S. lappa showed the presence of sesquiterpenes, anthraquinones, lignans, alkaloids, flavonoids, glycosides and steroids. Antimicrobial potential of subject plant was also investigated against three bacterial strains and maximum antibacterial activity was observed by CEE against S. aureus, CAE against P. aeruginosa, while CME, CEE, EAE and PEE showed almost same significant activity against E. coli. The CME (1000 …


Protective Effect Of Beta-Sitosterol Against Ethanol Toxemia, Dakota Cooper, April Boucher-Zamzo Sep 2017

Protective Effect Of Beta-Sitosterol Against Ethanol Toxemia, Dakota Cooper, April Boucher-Zamzo

Journal of Undergraduate Research at Minnesota State University, Mankato

Herbal medications have no indications of interactions with alcohol on their labels. There has been at least one clinical finding that saw palmetto with active ingredient beta-sitosterol used for enlarged male prostates caused pancreatic damage. This study with 20 male mice hypothesized that ethanol would increase the toxicity of beta-sitosterol. It was found that mice dosed by gavage with 0.1 ml of 95 proof ethanol died starting at the second dose and increased to 100% by the sixth dose (unexpected based on literature). 60-microgram injections of beta-sitosterol prevented deaths in 80% of the mice past the sixth dose opposite to …


The Impact Weather Has On Nyc Citi Bike Share Company Activity, Mark Martinez Jul 2017

The Impact Weather Has On Nyc Citi Bike Share Company Activity, Mark Martinez

Journal of Environmental and Resource Economics at Colby

This paper seeks to figure out the effect weather has on individuals’ behavior. A more focused approach to determining this effect is seeing how different weather conditions ranging from the temperature, the precipitation, the amount of inches of snowfall and the wind speed effect the ridership of Citi Bikes throughout all four seasons. The approach of this research paper is using data from the National Climatic Data Center that focuses in on the weather found in Manhattan, New York and correlates each of the weather conditions to the total number of trips per day that is provided by the Citi …


Electricity Demand Due To Policy Change In The U.K., Kevin W. Doherty Jul 2017

Electricity Demand Due To Policy Change In The U.K., Kevin W. Doherty

Journal of Environmental and Resource Economics at Colby

This paper examines United Kingdom Electricity Demand with regards to the Climate Change Act, which was enacted in November of 2008. Through actual demand data obtained from Nationalgrid, a U.K. based gas and electric utility company, this paper seeks to find out if the Climate Change Act has started to achieve its goal of reducing carbon emissions by looking at trends of electricity demand. Burning fossil fuels to produce electricity is a major contributor to global warming in the U.K. and policies enacted do not always live up to their ultimate goals. This paper tests how on track the Climate …


The Demographic Drivers Of California’S Environmental Voting, Lukas Yasuda Jul 2017

The Demographic Drivers Of California’S Environmental Voting, Lukas Yasuda

Journal of Environmental and Resource Economics at Colby

This study examines the demographics of California’s 53 congressional districts and the relationship with the voting patterns on three environmentally focused propositions in the 2008 and 2010 elections. Previous literature on the topic is mixed as some studies suggest that select attributes are found among environmental voting centers, yet other research describes the relationship as more complex than simple characteristics. Previous literature on the topic is mixed, with some studies suggesting that select attributes are found among environmental vote support hubs, whereas alternative research suggests the problem is more complex than simple characteristics. I collected data on income, education, age, …


How Individuals React To Smog Alerts In Beijing --Evidence From Beijing Subway Volume, Hanjing Shi Jul 2017

How Individuals React To Smog Alerts In Beijing --Evidence From Beijing Subway Volume, Hanjing Shi

Journal of Environmental and Resource Economics at Colby

This paper is going to find out the impact of smog alerts on individuals’ outdoor activities in Beijing. I use the subway volume to represent the outdoor activities. There are four levels of smog alerts in Beijing – blue, yellow, orange, and, red. The blue one is the lowest, and the red one is the highest. People in Beijing in all do not react to smog alerts in all statistically significant both on working days and weekends. But when combine orange alerts and red alerts together, the results show that people react to severe alerts differently during non-weekend days and …


The Effects From Public Transportation On Property Values: A Closer Look At Scituate, Hanover, And Norwell, Massachusetts, Alexandra Taylor Perticone, Christine S. Coveney Jul 2017

The Effects From Public Transportation On Property Values: A Closer Look At Scituate, Hanover, And Norwell, Massachusetts, Alexandra Taylor Perticone, Christine S. Coveney

Journal of Environmental and Resource Economics at Colby

Prior studies have expressed the value of location in real estate, but more recent studies have explored the influence that public transportation has had on housing prices. Access to public transportation is understood to increase the value of homes. Easier access to public transportation allows for shorter and more convenient commutes into or within cities. However, other studies have found that proximity to public transportation can also have adverse effects on property values. This paper investigates whether the implementation of the Greenbush Commuter line in Massachusetts in October 2007 increased the housing prices in Scituate, Ma--the furthest town from the …


Invited Introduction To Jerec, Matthew Kahn Jul 2017

Invited Introduction To Jerec, Matthew Kahn

Journal of Environmental and Resource Economics at Colby

No abstract provided.


Welcome By The Editor, Nathan W. Chan Jul 2017

Welcome By The Editor, Nathan W. Chan

Journal of Environmental and Resource Economics at Colby

No abstract provided.


The Mobile Monitoring Of Particulate Matter Through Wearable Sensors And Their Influence On Students' Environmental Attitudes, Joseph M. Abbate Jul 2017

The Mobile Monitoring Of Particulate Matter Through Wearable Sensors And Their Influence On Students' Environmental Attitudes, Joseph M. Abbate

DePaul Discoveries

While we have a comprehensive understanding of air pollutants, and their spatiotemporal characteristics across global, and even regional, scales, we are quite limited in our capacity to monitor neighborhood-scale emissions. The mobile monitoring of air pollution is a growing field, prospectively filling in these gaps while personalizing air quality-based tools and risk assessment. In the present study, we developed wearable sensors for particulate matter (PM); and through a citizen science approach, students of partnering Chicago schools monitored PM concentrations throughout their commutes over a five-day period. While their recorded findings would be used to explore the relationship between PM concentrations …


The Effects Of Isoprene Emission From Native And Invasive Trees On Local Air Quality, Aarti P. Mistry Jul 2017

The Effects Of Isoprene Emission From Native And Invasive Trees On Local Air Quality, Aarti P. Mistry

DePaul Discoveries

Biogenic volatile organic compounds (BVOC) are the second-most abundant reactive gasses emitted into the atmosphere by the biosphere. Isoprene is a BVOC produced by the process of photosynthesis from vegetation and is emitted from plant leaves. Isoprene is a hydrocarbon that combines with oxides of nitrogen in the atmosphere to create ozone in the troposphere, an air pollutant. Invasive trees alter ecosystems and affect native tree populations. Invasive tree species in the Chicagoland area are outcompeting native tree species and expanding rapidly. The effect of isoprene emissions on air quality is a well-researched area in the atmospheric science community, however, …


The Effects Of Fluoride Ions On Neuromuscular Activity And Regeneration In Dugesia Tigrina, John Williams Jr. Jun 2017

The Effects Of Fluoride Ions On Neuromuscular Activity And Regeneration In Dugesia Tigrina, John Williams Jr.

Georgia Journal of Science

Fluoride ions have been implicated in numerous nervous system pathologies, though the association of these ions with these conditions has been controversial. The purpose of this research is to determine the effects that fluoride ions have on the nervous system development and function in planarians as a simple model for fluoride-nervous system interactions. In the first set of experiments, planarians were exposed to one of four concentrations of sodium fluoride: 0 mM, 1 mM, 1 mM, and 5 mM. In the second set of experiments, planarians were bisected and exposed to 1 mM of NaCl and NaF for regeneration purposes. …


Investigating A Modern Midwestern Crisis: The Economy And Opioid Overdose Death In Ohio, Anna M. Gagliardo Jun 2017

Investigating A Modern Midwestern Crisis: The Economy And Opioid Overdose Death In Ohio, Anna M. Gagliardo

Undergraduate Economic Review

This paper examines the effect of local economic factors on the amount of opioid overdose deaths across counties in Ohio. Ohio leads the nation in opioid overdose deaths. The data examined spans all 88 counties of Ohio and compares 2009 and 2013 data, relying predominantly on Ohio Department of Health and US Census American Community Survey data. Using two linear regression models, I demonstrate that there is a significant correlation between insured rates and opioid overdose deaths in 2009 as well as a significant correlation between poverty rates and opioid overdose death rates in Ohio in 2013. Additionally, I show …


Asthma-Related Hospitalization And Emergency Room Visits In Oakland, Alondra Varela Apr 2017

Asthma-Related Hospitalization And Emergency Room Visits In Oakland, Alondra Varela

McNair Research Journal SJSU

The City of Oakland has seen diminished childhood asthma rates. During the last few years more children have been able to qualify for Medi-Cal and other health insurance plans under the Affordable Care Act (ACA). Local programs work together with Medi-Cal and ACA to reduce the number of symptoms related to asthma by making sure children from low-income communities have access to primary care, medicine, and treatment. Unfortunately, the asthma-related hospitalizations and emergency room visits among children have continued to increase. These rates are even higher in low-income communities located near highly trafficked areas. To investigate this phenomenon, this study …


Hiv-1 Protease Inhibitors From Marine Brown Alga: A Literature Review, Eric Nunez Aguilar Apr 2017

Hiv-1 Protease Inhibitors From Marine Brown Alga: A Literature Review, Eric Nunez Aguilar

McNair Research Journal SJSU

The human immunodeficiency virus type 1 (HIV-1) causes an infectious disease that if left untreated can progress to acquired immunodeficiency syndrome (AIDS) and be fatal. Finding a cure and more treatments for HIV has become a top priority in medical research, and due to the cost of synthetic HIV medication, finding a low-cost alternative is essential. Marine pharmacology has provided a possible solution to costly HIV medication through compounds derived from marine brown algae that inhibit the HIV-1 protease (PR). The objective of this study is to emphasize the necessity for further research in HIV-1 protease inhibition using marine wildlife-derived …


Hawkes Co. V. United States Army Corps Of Engineers, Sarah M. Danno Apr 2017

Hawkes Co. V. United States Army Corps Of Engineers, Sarah M. Danno

Public Land & Resources Law Review

A peat mining company will not be required to obtain a permit under the Clean Water Act to discharge dredged and fill material into wetlands. The United States District Court for the District of Minnesota held that the United States Army Corps of Engineers fell short in its attempts to establish jurisdiction over the wetlands by twice failing to show a significant nexus existed between the wetlands and navigable waters. Further, the district court enjoined the Corps from asserting jurisdiction a third time because it would force the mining company through a “never ending loop” of administrative law.


Niche By Basma Kavanagh, Vivian M. Hansen Feb 2017

Niche By Basma Kavanagh, Vivian M. Hansen

The Goose

Review of Basma Kavanagh's Niche.


Possible Mechanisms That Protect The Fetus From Maternal Rejection, Adina Ziemba-Goldfarb Jan 2017

Possible Mechanisms That Protect The Fetus From Maternal Rejection, Adina Ziemba-Goldfarb

The Science Journal of the Lander College of Arts and Sciences

There is no other foreign tissue transplant that has such a strongly parasitic relationship with its human host as the fetus. Although the fetus contains paternal genes, is completely tolerized by its maternal host in almost all pregnancies. This presents an immunological paradox and has generated a lot of attention from leading researchers in the reproductive and immunology fields. This paper reviews the leading explanations for this paradox; that it is attributed to a detailed mechanism of the maternal and fetal immune system in which tryptophan suppresses T-cells from attacking specific paternal cells, while maintaining a strong immune response against …


Full Issue: Volume 10, Number 2 Jan 2017

Full Issue: Volume 10, Number 2

The Science Journal of the Lander College of Arts and Sciences

No abstract provided.


Full Issue: Volume 11, Number 1 Jan 2017

Full Issue: Volume 11, Number 1

The Science Journal of the Lander College of Arts and Sciences

No abstract provided.


Docking, Synthesis, And Cytotoxic Activity Of N-4-Methoxybenzoyl-N’-(4-Fluorophenyl)Thiourea On Hela Cell Line, Anindi Lupita Nasyanka Jan 2017

Docking, Synthesis, And Cytotoxic Activity Of N-4-Methoxybenzoyl-N’-(4-Fluorophenyl)Thiourea On Hela Cell Line, Anindi Lupita Nasyanka

The Thai Journal of Pharmaceutical Sciences

Tiourea derivatives such as phenylthiourea, benzoyltiourea, tenovin, and many more have been reported as anticancer agent. In this study, we have done some initial step (docking, synthesis, and cytotoxic assay) to develop one of thiourea derivatives, N-4.


In Vitro Antimicrobial Activity Of Antidesma Bunius Extracts On Oral Pathogenic Bacteria, Panicha Pongnaratorn, Prakasit Kuacharan, Vayura Kotsuno, Naruwat Pakdee, Pranee Sriraj, Jintana Sattayasai Jan 2017

In Vitro Antimicrobial Activity Of Antidesma Bunius Extracts On Oral Pathogenic Bacteria, Panicha Pongnaratorn, Prakasit Kuacharan, Vayura Kotsuno, Naruwat Pakdee, Pranee Sriraj, Jintana Sattayasai

The Thai Journal of Pharmaceutical Sciences

High antioxidant content of Antidesma bunius may lead to many beneficial pharmaceutical properties such as an anti-bacterial, anti-inflammatory and somatic cell decelerations, as well as cancer prevention. This study aimed at quantifying total phenolic c.


High-Performance Thin-Layer Chromatography Analysis Of (E)-4-(3?,4?-Dimethoxyphenyl)But-3-En-1-Ol (Compound D) In Zingiber Cassumunar Roxb Rhizome Extract: An Application On Genetic Differentiation, Prasan Tangyuenyongwatana, Piyarat Parinyapong Chareonsap, Wandee Gritsanapan Jan 2017

High-Performance Thin-Layer Chromatography Analysis Of (E)-4-(3?,4?-Dimethoxyphenyl)But-3-En-1-Ol (Compound D) In Zingiber Cassumunar Roxb Rhizome Extract: An Application On Genetic Differentiation, Prasan Tangyuenyongwatana, Piyarat Parinyapong Chareonsap, Wandee Gritsanapan

The Thai Journal of Pharmaceutical Sciences

Objectives: This study focused on developing high performance thin-layer chromatography (HPTLC) quantitative analysis method for compound D, a major anti-inflammatory compound in Zingiber cassumunar extract. In addition, the amplified fragment length pol.


Stability Determination Of An Alternative Approach To Use Of Liquid Drug Substance As Oil Phase In Microemulsion Formulations: Methyl Salicylate, Warunee Leesajakul, Sunee Channarong, Pathamaporn Chuetee Jan 2017

Stability Determination Of An Alternative Approach To Use Of Liquid Drug Substance As Oil Phase In Microemulsion Formulations: Methyl Salicylate, Warunee Leesajakul, Sunee Channarong, Pathamaporn Chuetee

The Thai Journal of Pharmaceutical Sciences

The objective of this study was to investigate the stability of microemulsions using methyl salicylate as oil phase in the presence and the absence of hydrophobic additives and/or drug after six-month storage at ambient temperature. The investigated addi.


Isocratic Ultra-Performance Liquid Chromatographic Assay Of Quetiapine Fumarate In Pharmaceuticals, N Rajendra Prasad, Kanakapura Basavaiah Jan 2017

Isocratic Ultra-Performance Liquid Chromatographic Assay Of Quetiapine Fumarate In Pharmaceuticals, N Rajendra Prasad, Kanakapura Basavaiah

The Thai Journal of Pharmaceutical Sciences

An isocratic and reversed phase ultra-performance liquid chromatographic (RP-UPLC) method has been developed for the determination of quetiapine fumarate (QTF)) in bulk drug and in its tablets. The method was developed using AQUITY UPLC HSS T3 (2.1 x 50.


Analytical Method Development And Validation For Iron And Ascorbic Acid In Ferrous Bisglyciante Effervescent Tablets By Colorimetry And Rp-Hplc., Vasantharaju Sg Jan 2017

Analytical Method Development And Validation For Iron And Ascorbic Acid In Ferrous Bisglyciante Effervescent Tablets By Colorimetry And Rp-Hplc., Vasantharaju Sg

The Thai Journal of Pharmaceutical Sciences

A sensitive colorimetric and reverse phase high performance liquid chromatographic method was developed for estimation of total iron and ascorbic acid in ferrous bisglycinate effervescent tablets. A colorimetric method was developed for total iron us...


Hepatoprotective And Hepatoregenerative Therapeutic Effects Of Polyherbal Medicine Heparmin Tm On Rattus Norvegicus Wistar With Liver Fibrosis, Diana Lyrawati, Amalia Ghassani Muslimah, Dewi Laksmita, Dian Indrawati Santoso, Erlien Lindawati Poernomo, Karina Larasati, Lina Zahrotus Sajidah, Oktavia Rahayu Adianingsih, Rosida Dewi Agusningtyas, Mudjiwijono Handaru Eko, Bogi Pratomo Wibowo Jan 2017

Hepatoprotective And Hepatoregenerative Therapeutic Effects Of Polyherbal Medicine Heparmin Tm On Rattus Norvegicus Wistar With Liver Fibrosis, Diana Lyrawati, Amalia Ghassani Muslimah, Dewi Laksmita, Dian Indrawati Santoso, Erlien Lindawati Poernomo, Karina Larasati, Lina Zahrotus Sajidah, Oktavia Rahayu Adianingsih, Rosida Dewi Agusningtyas, Mudjiwijono Handaru Eko, Bogi Pratomo Wibowo

The Thai Journal of Pharmaceutical Sciences

Chronic injury severely impairs liver regeneration through excess inflammation, scarring and epithelial abnormalities, since injured cells may shift response from pro-regeneration into pro-fibrosis which leads to cirrhosis and total liver failure. An Ind.