Pharmacology, Toxicology and Environmental Health Commons^™

Anticancer Activity Of Some Boronic Acid Arylidene Heterocycles, Joy Kim

Honors Theses

This research was done in order to investigate the anticancer activity of boronic acid arylidene heterocycles. Boronic acid, heterocycles, and aryl compounds have all independently exhibited various anti-microbial properties and have shown potential to be used in pharmaceuticals for the treatment of viruses and cancers. Using a one-step protocol developed by Dr. Murray, several different arylheterocyclic compounds were combined with an arylboronic acid to synthesize novel compounds. These were then tested for their anti-cancer activity on glioblastoma brain cancer cells. Although varied in potency, all had some amount of anti-cellular effect on the cancer cells. This is only the start …

Framing Fracking: The Environmental And Social Implications Of Hyraulic Fracturing, Lindsay Cohen

Honors Theses

Hydraulic fracturing is a process currently used to obtain natural gas that is trapped in rock, which has low porosity and permeability. The natural gas obtained from this process had had positive impacts such as creating jobs and boosting our economy, but has also had some detrimental impacts on our environment, as well as people.

Kinetic Modeling Of Catalytic Aerogels, Yi Cao

Honors Theses

As pollution becomes an increasing concern globally, strict regulations have been set on vehicle pollutant emissions. The three-way catalytic converter is capable of converting toxic emissions such as carbon monoxide, unburned hydrocarbons and nitrogen oxides to less hazardous waste such as carbon dioxide, water, and nitrogen. Current catalysts employ platinum group metals, which are expensive and environmentally damaging to mine. Catalytically-active aerogels such as Co-Al, Cu-Al and V-Al aerogels have shown promise as alternatives to these metals. The work presented here adapts and extends a global kinetic model which predicts the conversion of hydrocarbons and carbon monoxide on platinum catalyst …

Sem-Edx Analysis Of Aerosol Samples, Xuanhan Zhao

Honors Theses

One of the important environmental issues in upstate New York is the acid rain problem in the Adirondack Mountains, which is associated with atmospheric aerosols. As a part of a systematic study to understand the transport, transformation, and effects of airborne pollutants in the Adirondack Mountains, we are performing an analysis of atmospheric aerosols collected at Piseco Lake. In previous work, we used proton induced X-ray emission (PIXE) [1] spectrometry to measure the concentrations of elements in aerosol samples as a function of the size of the particulate matter. The results of the PIXE analysis indicate significant concentrations of sulfur …

Ten Weeks With Green Beans...And Then Some: Determination Of Bisphenol-A (Bpa) In Canned Goods From Arkansas Markets Using Fluorescence Spectrophotometry, Rachel Pruett

Honors Theses

Bisphenol A (BPA) is a chemical widely used in production of consumer goods. It has come under scrutiny recently after being labeled as an endocrine disruptor (ED), mostly causing adverse effects in infants and young children. It has been associated with diabetes, cardiovascular disease, and abnormal maturation. Because it is so commonly used in product development, humans are exposed to BPA through various means, such as ingestion or dermal absorption. It is a concern that the combined exposure could cause serious effects even in small doses.

In canned foods, the chemical is made into an epoxy resin to provide a …

Studying The Effects Of Theraflu On The Growth Of Selenastrum Capricornutum, Hannah Gray Boren

Honors Theses

Algae contribute to self-purification of streams and rivers and are necessary as food for fish and as components of aquatic food webs (1). However, too much or too little algae may create or be indicative of a problem. If nutrients are present in large amounts, algae growth may become excessive, resulting in algal “blooms.” These algal blooms can change the chemistry of the water, making it toxic to other aquatic occupants, including fish, birds, animals, and other plants (1). On the other hand, if nutrients in the water are limiting or are exhausted, algae growth is inhibited, which results in …

Bringing Bpa To Light: Determination Of Bisphenol A In Thermal Receipt Paper Water Samples And Lake Water Samples Using Fluorescence Spectrophotometry, Bailey Chitwood

Honors Theses

Bisphenol A (BPA) is a chemical that is commonly used in harder plastic products, in the lining of food cans, and in thermal receipt paper. The usage of BPA in common products has become a concern for humans, especially for infants and young children, because of its effects as an endocrine disrupter. BPA has been linked to diabetes, cardiovascular disease, obesity, and certain developmental disorders. Because of the possible effects of BPA on the development of infants and young children, the use of BPA in baby bottles and other baby products has been outlawed. However, BPA is still used in …