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Pharmacology, Toxicology and Environmental Health Commons

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1993

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Articles 31 - 52 of 52

Full-Text Articles in Pharmacology, Toxicology and Environmental Health

Distribution Of Colchicine In Various Plant Parts Of Gloriosa Superba L., Nudchanart Kitcharoen, Wanchai De-Eknamkul Jan 1993

Distribution Of Colchicine In Various Plant Parts Of Gloriosa Superba L., Nudchanart Kitcharoen, Wanchai De-Eknamkul

The Thai Journal of Pharmaceutical Sciences

An analytical method of TLC-densitometry was developed for the determination of colchicine in various plant parts of Gloriosa superba L.. The method appeared to be simple and rapid since the step of crude extract purification prior to the analysis was no...


Anthraquinones From Xyris Indica, Nijsiri Ruangrungsi, Thatree Phadungcharoen, Suchada Suriyagan, Toshikazu Sekineb, Yuichi Fujiic, Isamu Murakoshi Jan 1993

Anthraquinones From Xyris Indica, Nijsiri Ruangrungsi, Thatree Phadungcharoen, Suchada Suriyagan, Toshikazu Sekineb, Yuichi Fujiic, Isamu Murakoshi

The Thai Journal of Pharmaceutical Sciences

Three anthraquinones, chrysazin(l), 3-methoxychrysazin (2) and 3-hydroxy -chrysazin (3), have been isolated from theflowering heads of Xyris indica L. 3-Hydroxy -chrysazin ( 1,3,8-trihydroxy -9,10-anthracenedione) is new plant constituent. Antimicrobial ...


Effect Of Alcohol On The Postnatal Development Of Cerebellar Cortex In Rat Guste 1-Histological And Morphometric Studies., Mansoor Saleh, M N. Saleh, M A. Desouky, Saadia Sayed, Entesar Saber Jan 1993

Effect Of Alcohol On The Postnatal Development Of Cerebellar Cortex In Rat Guste 1-Histological And Morphometric Studies., Mansoor Saleh, M N. Saleh, M A. Desouky, Saadia Sayed, Entesar Saber

Haematology and Oncology, East Africa

The effect of ethyl alcohol (10%) on the postnatal development of cerebellar cortex was studied using histological and morphometric methods. The external granular layer was much increased in thickness in alcohol fed rat than those of the control while the molecular and granular layer were reduced. The cells of themolecular layer showed neuronal degeneration and many spaces were present in this layer esp < /strong>ecially late postnatal. The Purkinje cells failed to reach their final position up the tenth day and still arranged in more than one row. The degenerative changes appeared at five days and increased with age. The extent …


Variation In Powder Characteristics Of Indomethacin From Various Sources, Satit Puttipipatkhachorn, Ampol Mitrevej, Vanisara Papangkornkij, Vipa Srivichitchok Jan 1993

Variation In Powder Characteristics Of Indomethacin From Various Sources, Satit Puttipipatkhachorn, Ampol Mitrevej, Vanisara Papangkornkij, Vipa Srivichitchok

The Thai Journal of Pharmaceutical Sciences

Powder characteristics of indomethacin powder purchased from three different suppliers were studied. Moisture content, particle shape, particle size, polymorphism and particulate dissolution were determined. All of the indomethacin powder studied were of y-polymorph. This study demonstrated that particulate dissolution rate of indomethacin powder increased with decreased particle size.


Naphthoquiones And A Sterol From Impatiens Balsamina L. Root Cultures, Pharkphoom Panichayupakaranant, Hiroshi Noguchi, Wanchai De-Eknamkul, Uchio Sankawa Jan 1993

Naphthoquiones And A Sterol From Impatiens Balsamina L. Root Cultures, Pharkphoom Panichayupakaranant, Hiroshi Noguchi, Wanchai De-Eknamkul, Uchio Sankawa

The Thai Journal of Pharmaceutical Sciences

A binaphthoquinone; diphthiocol, two naphthoquinones; lawsone and 2-methoxy -1,4-naphthoquinone, and a sterol; spinasterol, were isolated from the root cultures of Impatiens balsamina . Their structures were established on the basis of UV, IR, mass, 1H NMR and 13C NMR spectral data. Diphthiocol is a new natural product in which its synthesis has been reported.


Variation In Powder Characteristics Of Indomethacin From Various Sources, Satit Puttipipatkhachorn, Ampol Mitrevej, Vanisara Papangkornkij, Vipa Srivichitchok Jan 1993

Variation In Powder Characteristics Of Indomethacin From Various Sources, Satit Puttipipatkhachorn, Ampol Mitrevej, Vanisara Papangkornkij, Vipa Srivichitchok

The Thai Journal of Pharmaceutical Sciences

Powder characteristics of indomethacin powder purchased from three different suppliers were studied. Moisture content, particle shape, particle size, polymorphism and particulate dissolution were determined. All of the indomethacin powder studied were of y-polymorph. This study demonstrated that particulate dissolution rate of indomethacin powder increased with decreased particle size.


Monolignan An Diterpene Glycosides From The Stem Of Tinsospora Rumphii Boerl., Isamu Murakoshi, Toshikazu Sekine, Hideyuki Suzuki, Chihiro Ninomiya, Kazuki Saito, Siriporn Okonogi, Fumio Ikegami Jan 1993

Monolignan An Diterpene Glycosides From The Stem Of Tinsospora Rumphii Boerl., Isamu Murakoshi, Toshikazu Sekine, Hideyuki Suzuki, Chihiro Ninomiya, Kazuki Saito, Siriporn Okonogi, Fumio Ikegami

The Thai Journal of Pharmaceutical Sciences

From dried stems of Tinospora rumphii Boerl. (Menispermaceae), a monolignan glycoside, syringin (1), and a diterpene glycoside, borapetoside B (2), were isolated. The structures of 1 and 2 were elucidated by spectroscopic and enzymatic studies. The amino acid composition and content in ethanol extract of the stems have also been studied.


ระบบยูนิตโดส : คำตอบของปัญหาการกระจายยาในโรงพยาบาล ? (Unit Dose System : The Answer To Your Problems?, อภิฤดี เหมะจุฑา Jan 1993

ระบบยูนิตโดส : คำตอบของปัญหาการกระจายยาในโรงพยาบาล ? (Unit Dose System : The Answer To Your Problems?, อภิฤดี เหมะจุฑา

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Monolignan An Diterpene Glycosides From The Stem Of Tinsospora Rumphii Boerl., Isamu Murakoshi, Toshikazu Sekine, Hideyuki Suzuki, Chihiro Ninomiya, Kazuki Saito, Siriporn Okonogi, Fumio Ikegami Jan 1993

Monolignan An Diterpene Glycosides From The Stem Of Tinsospora Rumphii Boerl., Isamu Murakoshi, Toshikazu Sekine, Hideyuki Suzuki, Chihiro Ninomiya, Kazuki Saito, Siriporn Okonogi, Fumio Ikegami

The Thai Journal of Pharmaceutical Sciences

From dried stems of Tinospora rumphii Boerl. (Menispermaceae), a monolignan glycoside, syringin (1), and a diterpene glycoside, borapetoside B (2), were isolated. The structures of 1 and 2 were elucidated by spectroscopic and enzymatic studies. The amino acid composition and content in ethanol extract of the stems have also been studied.


Biosynthesis In Vitro Of Some Neurotoxic Amino Acids In Lathyrus Species, Fumio Ikegami, Yu-Haey Kuo, Fernand Lambein, Isamu Murakoshi Jan 1993

Biosynthesis In Vitro Of Some Neurotoxic Amino Acids In Lathyrus Species, Fumio Ikegami, Yu-Haey Kuo, Fernand Lambein, Isamu Murakoshi

The Thai Journal of Pharmaceutical Sciences

Two different forms of cysteine synthase (CSase) were purified from the grass pea (Lathyrus sativus), being separated by chromatography on DEAE-Sepharose Fast Flow or EAH-Sepharose 4B. Data on the substrate specificity show that both isoenzymes catalyse ...


Formulation Of Sustained Release Mosquito Larvicidal Preparations From Bacillus Sphaericus(การเตรียมผลิตภัณฑ์ฆ่าลูกนํ้ายุงออกฤทธิ์นาน จากเชื้อแบซิ..., Ruedee Saowakonth, Yupin Rungvejhavuttivittaya, Narong Sarisuta, Suthin Siripraiwan, Puangpen Suyanandana Jan 1993

Formulation Of Sustained Release Mosquito Larvicidal Preparations From Bacillus Sphaericus(การเตรียมผลิตภัณฑ์ฆ่าลูกนํ้ายุงออกฤทธิ์นาน จากเชื้อแบซิ..., Ruedee Saowakonth, Yupin Rungvejhavuttivittaya, Narong Sarisuta, Suthin Siripraiwan, Puangpen Suyanandana

The Thai Journal of Pharmaceutical Sciences

The mosquito larvicidal preparations of Bacillus sphaericus were formulated in the form of sustained release granules by using dibasic calcium phosphate, talc.Avicel PH 101, and ethylcellulose as carriers. The obtained products possessed satisfactorily l...


Identification And Specification Of Khaao-Yen-Nuea Khaao-Yen-Tai(การตรวจพิสูจน์และการทำข้อกำหนดของข้าวเย็นเหนือ ข้าวเย็นใต้), Laddawan Boonyaratanakornkit, Vanida Chantarateptawan Jan 1993

Identification And Specification Of Khaao-Yen-Nuea Khaao-Yen-Tai(การตรวจพิสูจน์และการทำข้อกำหนดของข้าวเย็นเหนือ ข้าวเย็นใต้), Laddawan Boonyaratanakornkit, Vanida Chantarateptawan

The Thai Journal of Pharmaceutical Sciences

Specification of Khaao - Yen - Nuea Khaao - Yen - Tai of the 4 authentic - plant drugs has been carried out on the morphological of plants, macroscopical and microscopical (histology and powdered drug) characteristic, limit of moisture content, total ash...


Two New Isocoumarins From Xyris Indica, Nijsiri Ruangrungsi, Toshikazu Sekine, Thatree Phadungcharoen, Suchada Suriyagan, Isamu Murakoshi Jan 1993

Two New Isocoumarins From Xyris Indica, Nijsiri Ruangrungsi, Toshikazu Sekine, Thatree Phadungcharoen, Suchada Suriyagan, Isamu Murakoshi

The Thai Journal of Pharmaceutical Sciences

Two new isocoumarins named xyridin A and B were isolated from the chloroform extract of the flowering heads of Xyris indica (Xyridaceae). Their structures have been established as 3-n-propyl-6,7-(methylenedioxy)-1H-2- benzopyran-1-one and 3-(r-oxopropyl)...


Two Sterols From Xyris Indica, Nijsiri Ruangrungsi, Thatree Phadungcharoen, Suchada Suriyagan, Toshikazu Sekine, Isamu Murakoshi Jan 1993

Two Sterols From Xyris Indica, Nijsiri Ruangrungsi, Thatree Phadungcharoen, Suchada Suriyagan, Toshikazu Sekine, Isamu Murakoshi

The Thai Journal of Pharmaceutical Sciences

Examination of the flowering heads of Xyris indica (Xyridaceae) revealed the presence of PA'o sterols : stigmasterol and spinasterol.


Effects Of Some Edible Plants On The Differentiation Of U-937 Human Myeloid Leukemia Cells, Masuko Kobori, Yasuhide Miyama, Tojiro Tsushida, Hiroshi Shinmoto, Kazuki Shinohara Jan 1993

Effects Of Some Edible Plants On The Differentiation Of U-937 Human Myeloid Leukemia Cells, Masuko Kobori, Yasuhide Miyama, Tojiro Tsushida, Hiroshi Shinmoto, Kazuki Shinohara

The Thai Journal of Pharmaceutical Sciences

The effects of non-dialyzable extracts of some edible plants, such as red pepper, sugarcane, parsley, Gymnema sylvestre and Bupleurum falcatum, on the differentiation of U-937 human myeloid leukemia cells were examined. The extract ofG. sylvestre and par...


Screening Of Enzyme Activities In Crude Drugs (I) — B-Glucuronidase In Scutellariae Radix —, Fumio Ikegami, Kaori Matsunae, Takashi Kurihara, Takeshi Yamamoto, Isamu Murakoshi Jan 1993

Screening Of Enzyme Activities In Crude Drugs (I) — B-Glucuronidase In Scutellariae Radix —, Fumio Ikegami, Kaori Matsunae, Takashi Kurihara, Takeshi Yamamoto, Isamu Murakoshi

The Thai Journal of Pharmaceutical Sciences

B~Glucuronidase (GUS) activity in the crude drug, Scutellariae Radix, was assayed in line with the quality control of Kampo {Japanese herbal) medicines. GUS was purified to homogeneity in the purification steps including CM-Sepharose Fast Flow and clirom...


Constituents Of Atherolepis Pierrei, Sunee Chansakaow, Thatree Phadungcharoen, Nijsiri Ruangrungsi, Toshikazu Sekineb, Isamu Murakoshi Jan 1993

Constituents Of Atherolepis Pierrei, Sunee Chansakaow, Thatree Phadungcharoen, Nijsiri Ruangrungsi, Toshikazu Sekineb, Isamu Murakoshi

The Thai Journal of Pharmaceutical Sciences

Examination of the chloroform extract from the root of Atherolepis pierrei (Asclepiadaceae) revealed the presence of a long chain hydrocarbon, heptatriacontane together with an aromatic principle, 2-hydroxy-4-methoxy benzaldehyde and three triterpenoids,...


ระบบยูนิตโดส : คำตอบของปัญหาการกระจายยาในโรงพยาบาล ? (Unit Dose System : The Answer To Your Problems?, อภิฤดี เหมะจุฑา Jan 1993

ระบบยูนิตโดส : คำตอบของปัญหาการกระจายยาในโรงพยาบาล ? (Unit Dose System : The Answer To Your Problems?, อภิฤดี เหมะจุฑา

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Amino Acid Composition And Contents Of Some Thai Medicinal Plants, Fumio Ikegami, Terumi Fukuda, Nijsiri Ruangrungsi, Isamu Murakoshi Jan 1993

Amino Acid Composition And Contents Of Some Thai Medicinal Plants, Fumio Ikegami, Terumi Fukuda, Nijsiri Ruangrungsi, Isamu Murakoshi

The Thai Journal of Pharmaceutical Sciences

Examination of the amino acid composition and contents in ethanol extracts from 6 species of Thai medicinal plants revealed that Mucuna collettii contained a large amount of L-DOPA (62.5 umol/g dry wt) which occupied about 83% of all free amino acids in this plant. Some plants yielded a relative high amount of GABA as a major amino acid.


Hypoglycemic Effect Of Tecoma Stans, Chomphu Sripratak, Chumpol Sriudom, Kiattigul Chantevalikhit, Pornpimol Kijsanayotin, Suratana Amnuaypol Jan 1993

Hypoglycemic Effect Of Tecoma Stans, Chomphu Sripratak, Chumpol Sriudom, Kiattigul Chantevalikhit, Pornpimol Kijsanayotin, Suratana Amnuaypol

The Thai Journal of Pharmaceutical Sciences

The total alkaloid salt (picrate salt) from the leaves of Tecoma stans (Juss.) HBK. , orally administered to normal rats, produced a hypoglycemic effect.


Enzymic 12-Hydroxylation And 12-O-Methylation Of Dihydrochelirubine In Dihydromacarpine Formation By Thalictrum Bulgaricum, Lothar Kammerer, Wanchai De-Eknamkul, Meinhart H. Zenk Jan 1993

Enzymic 12-Hydroxylation And 12-O-Methylation Of Dihydrochelirubine In Dihydromacarpine Formation By Thalictrum Bulgaricum, Lothar Kammerer, Wanchai De-Eknamkul, Meinhart H. Zenk

The Thai Journal of Pharmaceutical Sciences

Two novel enzymes, dihydrochelirubine-12-hydroxylase and SAM: 12-hydroxydihy drochelirubine-12-O- methyltransferase have been discovered in cell-free extracts of yeast-elicited Thalictrum bulgaricum VEL. cell cultures. Both enzymes are involved in the la...


อีกก้าวของโครงการพัฒนา อาจารย์เภสัชศาสตร์, N/A Jan 1993

อีกก้าวของโครงการพัฒนา อาจารย์เภสัชศาสตร์, N/A

The Thai Journal of Pharmaceutical Sciences

No abstract provided.