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Extracellular Microvesicles As A Novel Biomarker For Wound Healing, Walid Omran Mari
Extracellular Microvesicles As A Novel Biomarker For Wound Healing, Walid Omran Mari
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Introduction: Wound healing is a sophisticated dynamic process that involves complex coordination among a variety of resident cells in a suitable extracellular environment. Chronic wounds are defined as wounds that fail to heal within a period of 3 months. Negative pressure wound therapy (NPWT) is a closed suction drainage system is used to enable mass transport of fluid from the body as an adjunct to surgical procedures. (Oasis-ultra) is a triple layer extracellular matrix containing different types of glycosaminoglycans (GAGs) like heparin sulfate, hyaluronic acid and chondroitin sulfate. In addition, it has adhesion molecule such as fibronectin and laminin along …
Usage Of Extracellular Microvesicles As Novel And Promising Therapeutic Tool In Wound Healing, Sami Gamaleddin F. Alsabri
Usage Of Extracellular Microvesicles As Novel And Promising Therapeutic Tool In Wound Healing, Sami Gamaleddin F. Alsabri
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Introduction Extracellular Microvesicles (EMVs) can carry genetic messages and biologically active proteins throughout tissues and the body. Because of their transport capabilities, EMVs play an important role both diseased and healthy conditions. For example, EMVs play an important regenerative role in many damaged tissues. In the current studies, we examine the role of EMVs in epithelial wound healing. The potential use of EMVs as drug delivery vehicles has gained considerable scientific interest because they can be delivered in circulation, can be targeted to specific areas/cells, and can pass natural barriers. In the current work, we investigate the potential of EMVs …
Effect Of Oasis-Ultra Matrix On The Healing Rate Of Stage Iv Pressure Wounds, Abdelfatah Shaban Abou Issa
Effect Of Oasis-Ultra Matrix On The Healing Rate Of Stage Iv Pressure Wounds, Abdelfatah Shaban Abou Issa
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Introduction: (Oasis-ultra) is an extra cellular collagen rich matrix derived from porcine intestinal sub-mucosa. A prospective, multi-centered, randomized, single-blinded clinical trial was conducted to study the effects of Oasis-ultra combined with negative pressure wound therapy (NPWT) on the healing rate of stage IV pressure wounds versus NPWT alone. Materials and Methods: Twelve subjects were involved in the study: six patients in the study group and six in the control group. NPWT was changed twice a week for all subjects, and Oasis-ultra was applied weekly. The wounds were measured weekly, and the healing rate was calculated for each subject for 12 …