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Pharmacology, Toxicology and Environmental Health Commons™
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Full-Text Articles in Pharmacology, Toxicology and Environmental Health
In Silico Screening Of Violacein As An Epidermal Growth Factor Receptor Inhibitor, Smitha S Bhat, Sindhu R, Shashanka K Prasad
In Silico Screening Of Violacein As An Epidermal Growth Factor Receptor Inhibitor, Smitha S Bhat, Sindhu R, Shashanka K Prasad
International Journal of Health and Allied Sciences
EGFR is a key player in the signalling cascades of various kinds of cancers and tyrosine kinase inhibitors block EGFR signalling. Natural products have long been used as candidates for therapy in the management of cancer. Violacein, a bacterial pigment, has been known for its numerous biological applications such as antimicrobial, antileishmanial, antiviral, as well as antitumoral. Computational studies have concluded that it may have activity against cancers like pancreatic cancer, thyroid cancer, colorectal cancer, and endometrial cancer indicating its potential application as a broad range of anti-cancerous drug. This study aimed to perform the molecular docking of violacein with …
Understanding The Status Of Important Criteria Air Pollutants And Its Health Effects – A Review, Christeena Varghese, Lingaraju H G, Shankramma Kalikeri
Understanding The Status Of Important Criteria Air Pollutants And Its Health Effects – A Review, Christeena Varghese, Lingaraju H G, Shankramma Kalikeri
International Journal of Health and Allied Sciences
In India, airborne pollutant is serious, and a growing illness cause of concern, adding considerably to the country's disease burden. Atmospheric effects are generally known to have several harmful health implications. India's air pollution has risen significantly because of population expansion, rising vehicle numbers, fuel usage, inefficient transit networks, poor land use patterns, industrialisation, and most importantly, insufficient environmental legislation. Because air pollution is a major factor, this has an impact on human health. People gradually understood that contaminated outdoor air had detrimental consequences on human health. Hypercholesterolemia, breathing problems, chronic obstructive pulmonary disease (COPD), and asthma are all connected …