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Articles 301 - 330 of 1538
Full-Text Articles in Pharmacology, Toxicology and Environmental Health
Synthesis And Evaluation Of Pi3kγ Enzyme Inhibitory Activity Of Novel (1h-Pyrazol-4-Yl)Methanamine, Sukumar Bepary, In Kwon Youn, Hee-Jong Lim, Ge Hyeong Lee
Synthesis And Evaluation Of Pi3kγ Enzyme Inhibitory Activity Of Novel (1h-Pyrazol-4-Yl)Methanamine, Sukumar Bepary, In Kwon Youn, Hee-Jong Lim, Ge Hyeong Lee
The Thai Journal of Pharmaceutical Sciences
A series of (1H-pyrazol-4-yl)methanamines have been synthesized and then were evaluated for the PI3Kγ enzyme inhibitory potential. Minor modification of the initially synthesized molecules offered significant improvement of the inhibitory potential from...
Cross Immediate Hypersensitivity Between Ciprofloxacin And Levofloxacin: A Case Report And Literature Review, Chotirat Nakaranurack
Cross Immediate Hypersensitivity Between Ciprofloxacin And Levofloxacin: A Case Report And Literature Review, Chotirat Nakaranurack
The Thai Journal of Pharmaceutical Sciences
Fluoroquinolones can show cross-reactivity because of the similar chemical structure. Levofloxacin is a new fluoroquinolone and can be a safe alternative due to low cross-reactivity. This is a case report showing cross-reactivity between ciprofloxacin an...
Development Of Miconazole Nitrate Loaded Micellar Gel For Improved Topical Delivery, Manish Kumar
Development Of Miconazole Nitrate Loaded Micellar Gel For Improved Topical Delivery, Manish Kumar
The Thai Journal of Pharmaceutical Sciences
The objective of the present investigation was to develop micellar gel of miconazole nitrate using amphiphilic block co-polymer pluronic F-127. Miconazole nitrate was entrapped into the micelles at critical micelle concentration by dialysis method and F2...
Pharmacy Students’ Attitudes And Perceptions About Complementary And Alternative Medicine: A Systematic Review, Mohd Shahezwan Abd Wahab, Phantipa Sakthong, Win Winit-Watjana
Pharmacy Students’ Attitudes And Perceptions About Complementary And Alternative Medicine: A Systematic Review, Mohd Shahezwan Abd Wahab, Phantipa Sakthong, Win Winit-Watjana
The Thai Journal of Pharmaceutical Sciences
Complementary and alternative medicine (CAM) is extensively used worldwide. The attitudes and perceptions of pharmacy students about CAM may influence their practices upon graduation. In this work, a systematic review was conducted by searching available...
Hepatoprotective And Nephrotoxic Effects Of Methanol Leaf Extract Of Telfairia Occidentalis (Hook F.) In Adult Female Albino Rats (Rattus Norvegicus), Chidozie Nwabuisi Okoye, John Ikechukwu Ihedioha, Onyinyechukwu Ada Agina, Izuchukwu Ochiogu, David Ogwu
Hepatoprotective And Nephrotoxic Effects Of Methanol Leaf Extract Of Telfairia Occidentalis (Hook F.) In Adult Female Albino Rats (Rattus Norvegicus), Chidozie Nwabuisi Okoye, John Ikechukwu Ihedioha, Onyinyechukwu Ada Agina, Izuchukwu Ochiogu, David Ogwu
The Thai Journal of Pharmaceutical Sciences
The leaf extract of the plant Telfairia occidentalis, commonly known as fluted pumpkin is used as a hematinic by post-menstrual and pregnant women and for treatment of many different ailments with little consideration of their toxic potentials. This stud...
Predicting The Duration Of Antibacterial Treatment With Cell Wall Synthesis Inhibitors By Using Mathematical Models, Panit Suavansri
Predicting The Duration Of Antibacterial Treatment With Cell Wall Synthesis Inhibitors By Using Mathematical Models, Panit Suavansri
The Thai Journal of Pharmaceutical Sciences
This paper proposed a new mathematical model of within-host population dynamics of bacteria after cell wall synthesis inhibitors administration for practically predicting treatment duration and drug dosage. Our model deployed various concepts from differ...
Developing A Signal Triage Algorithm For Thai National Adverse Drug Reaction Database, Suntharee T. Chaisumritchoke
Developing A Signal Triage Algorithm For Thai National Adverse Drug Reaction Database, Suntharee T. Chaisumritchoke
The Thai Journal of Pharmaceutical Sciences
There was increasing adverse drug reaction (ADR) reports submitted to the Health Product Vigilance Center under the Thai FDA. In order to find some signals, the Thai Signal Detection Program was developed to identify and filter the potential signals, cal...
Factors Affecting Community Pharmacists’ Intention To Provide Medication Management Program And Disease Screening In Bangkok, Payungjit Kangwol, Puree Anantachoti
Factors Affecting Community Pharmacists’ Intention To Provide Medication Management Program And Disease Screening In Bangkok, Payungjit Kangwol, Puree Anantachoti
The Thai Journal of Pharmaceutical Sciences
Objectives: To determine factors affecting community pharmacists’ intention to provide medication management program (MMP) and disease screening (DS) based on diffusion of innovations theory. Methods: A cross-sectional study using self-administered ma...
Docking And Molecular Dynamic Simulations: Study Of 1, 3, 4-Oxadiazole- Chalcone Hybrid Derivatives To Search New Active Anticancer Agents, Adel Zamri, Neni Frimayanti, Hilwan Yuda Teruna
Docking And Molecular Dynamic Simulations: Study Of 1, 3, 4-Oxadiazole- Chalcone Hybrid Derivatives To Search New Active Anticancer Agents, Adel Zamri, Neni Frimayanti, Hilwan Yuda Teruna
The Thai Journal of Pharmaceutical Sciences
Chalcone hybrid derivatives are one of the anti cancer promising agents. Computational approach (i.e. molecular docking) was applied in this study to search chalcone hybrids derivatives as new anti cancer agents. Blind docking of 81 chalcone derivatives ...
One Pot Synthesis And Docking Study Of Some Tetrahydrobenzo[B]Pyran Derivatives As Extended Spectrum Class Lactamase Inhibitors For Urinary Tract Infection, Prafulla Balkrishna Choudhari
One Pot Synthesis And Docking Study Of Some Tetrahydrobenzo[B]Pyran Derivatives As Extended Spectrum Class Lactamase Inhibitors For Urinary Tract Infection, Prafulla Balkrishna Choudhari
The Thai Journal of Pharmaceutical Sciences
A series of tetrahydrobenzo[b] pyran derivatives were synthesized and screened for the antimicrobial activity against Proteus vulgaris. Structures of newly synthesized compounds were confirmed by physicochemical, spectral and elemental analysis. The dock...
Comparison Of Validated Hplc Methods Using Two Derivatizing Agents For Gamma-Aminobutyric Acid Quantification, Kritchapol Panrod, Anyarporn Tansirikongkol, Vipaporn Panapisal
Comparison Of Validated Hplc Methods Using Two Derivatizing Agents For Gamma-Aminobutyric Acid Quantification, Kritchapol Panrod, Anyarporn Tansirikongkol, Vipaporn Panapisal
The Thai Journal of Pharmaceutical Sciences
Gamma-aminobutyric acid (GABA) has many advantages in physiological functions and skin benefits. Therefore, a feasible and simple method is needed for its determination. The purpose of this study was to validate and compare two HPLC analyses of GABA afte...
Evaluation Of The Methanol Whole Root Extract Of Securidaca Longipedunculata For Antitrypanosomal Activity In Vitro And In Vivo, Eke Ifeanyi Gabriel, Ihedioha Thelma Ebere, Ezeh Ikenna Onyema, Ezeudu Terry Adaku, Eze Ukamaka Uchenna, Okoye Chidozie Nwabuisi, Anaga Aruh Otah
Evaluation Of The Methanol Whole Root Extract Of Securidaca Longipedunculata For Antitrypanosomal Activity In Vitro And In Vivo, Eke Ifeanyi Gabriel, Ihedioha Thelma Ebere, Ezeh Ikenna Onyema, Ezeudu Terry Adaku, Eze Ukamaka Uchenna, Okoye Chidozie Nwabuisi, Anaga Aruh Otah
The Thai Journal of Pharmaceutical Sciences
Securidaca longipedunculata is a medicinal plant used in different parts of Africa for treatment of various ailments including sleeping sickness in Northern Nigeria. On this basis, the methanol root extract of S. longipedunculata was investigated for ant...
Effect Of Vitamin E Supplementation On Inflammatory Markers And Nutrition Status In Thalassemia Intermedia Patients, Watcharee Prapawatwech, Bunchoo Pongtanakul, Kulwara Meksawan
Effect Of Vitamin E Supplementation On Inflammatory Markers And Nutrition Status In Thalassemia Intermedia Patients, Watcharee Prapawatwech, Bunchoo Pongtanakul, Kulwara Meksawan
The Thai Journal of Pharmaceutical Sciences
Inflammation is a complication found in thalassemic patients. It may be diminished by supplementation of vitamin E. The purpose of this study was to investigate the effects of 12-week vitamin E supplementation on inflammatory markers in patients with tha...
Short Native Α-Helical Cationic Antimicrobial Peptides: Promising Alternative Antibiotics, Jiraphun Jittikoon
Short Native Α-Helical Cationic Antimicrobial Peptides: Promising Alternative Antibiotics, Jiraphun Jittikoon
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Synthesis And Characterization Of Sodium Alginate Conjugate: Preparation And Evaluation Of Transdermal Patches Of Losartan Potassium Using Sodium Alginate Conjugate, Satheesha Babu Bk, Srinivasa Rao K
Synthesis And Characterization Of Sodium Alginate Conjugate: Preparation And Evaluation Of Transdermal Patches Of Losartan Potassium Using Sodium Alginate Conjugate, Satheesha Babu Bk, Srinivasa Rao K
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Relationship Between Carbamazepine Concentrations In Serum And Saliva Of Thai Epileptic Patients, Piyaporn Kaewdoung, Chartchai Puripokai, Chartchai Puripokai, Mayuree H. Tantisira, Somsong Laanwprasert
Relationship Between Carbamazepine Concentrations In Serum And Saliva Of Thai Epileptic Patients, Piyaporn Kaewdoung, Chartchai Puripokai, Chartchai Puripokai, Mayuree H. Tantisira, Somsong Laanwprasert
The Thai Journal of Pharmaceutical Sciences
This study aims to examine and verify the correlation between serum and saliva carbamazepine concentrations in Thai epileptic patients. The subjects were patients aged 15-60 years old who were under treatment with carbamazepine. Carbamazepine concentrati...
Development And Validation Of A Stability-Indicating Ultra-Performance Liquid Chromatographic Method For The Determination Of Rifampicin In Bulk Drug And Capsules, N. Swamy, K. Basavaiah, P. Vamsikrishna, G. Krishnamurthy
Development And Validation Of A Stability-Indicating Ultra-Performance Liquid Chromatographic Method For The Determination Of Rifampicin In Bulk Drug And Capsules, N. Swamy, K. Basavaiah, P. Vamsikrishna, G. Krishnamurthy
The Thai Journal of Pharmaceutical Sciences
A rapid method based on ultra-performance liquid chromatography (UPLC) was developed and validated for the specific determination of anti-tuberculosis drug rifampicin (RIF) in bulk form and capsules. The UPLC determination was carried out on a reversed-p...
Synthesis Of Novel Fused Heterocyclic Pyrazolo-Pyridazine Derivatives As Antimicrobial Agents, M. Alam, M. S. Zaman, K. Arora, A. Ahmad, S. A. Khan, A. Husain
Synthesis Of Novel Fused Heterocyclic Pyrazolo-Pyridazine Derivatives As Antimicrobial Agents, M. Alam, M. S. Zaman, K. Arora, A. Ahmad, S. A. Khan, A. Husain
The Thai Journal of Pharmaceutical Sciences
A series of pyrazolo-pyridazine derivatives (4a-j) were synthesized and evaluated for their antimicrobial activities with an aim to obtain promising antimicrobial agents. In the first step, 6-substituted phenyl-2,3,4,5- tetrahydropyridazin-3-one (2a,b) w...
Application Of Proteoglycans From Fish Cartilage For The Acceleration Of Burn Wound Healing, Sitthiphon Bunman, Pornanong Aramwit, Noppadol Larbcharoensub, Pasarapa Towiwat
Application Of Proteoglycans From Fish Cartilage For The Acceleration Of Burn Wound Healing, Sitthiphon Bunman, Pornanong Aramwit, Noppadol Larbcharoensub, Pasarapa Towiwat
The Thai Journal of Pharmaceutical Sciences
Cartilage contains a variety of proteoglycans (PGs) that can accelerate wound healing. The aim of this study was to evaluate the efficacy of proteoglycans extracted from fish cartilage for the acceleration of burn wound healing. Second degree burn wounds...
Evaluation Of Anti-Anxiety Activity Of Melissa Parviflora (Benth.) In Rats, Kundan Singh Bora, Aruna Dubey
Evaluation Of Anti-Anxiety Activity Of Melissa Parviflora (Benth.) In Rats, Kundan Singh Bora, Aruna Dubey
The Thai Journal of Pharmaceutical Sciences
Melissa parviflora Benth. (Family: Lamiaceae) has been traditionally used as a tranquillizer, relaxants, nervine and sleeping aids throughout the world. The plant is reported to relieve tension and stress reactions, and widely valued for its calming prop...
In Vitro Biological Activities Of Black Pepper Essential Oil And Its Major Components Relevant To The Prevention Of Alzheimer’S Disease, Pattamapan Lomarat, Kittisak Sripha, Phanida Phanthong, Worawan Kitphati, Krit Thirapanmethee, Nuntavan Bunyapraphatsara
In Vitro Biological Activities Of Black Pepper Essential Oil And Its Major Components Relevant To The Prevention Of Alzheimer’S Disease, Pattamapan Lomarat, Kittisak Sripha, Phanida Phanthong, Worawan Kitphati, Krit Thirapanmethee, Nuntavan Bunyapraphatsara
The Thai Journal of Pharmaceutical Sciences
Black pepper oil and its major components were investigated for the biological activities related to the prevention of AD. The inhibition of acetylcholinesterase (AChE) and β-amyloid aggregation, anti-inflammatory and antioxidant activities were examine...
Phytofabrication Of Silver Nanoparticles Using Horse Gram (Dolichos Biflorus L.) Seed Extract And Assessment Of Its Bactericidal And Antioxidant Activities, Mahadevan Vijayalakshmi, Thangavel Rajagopal, Jeyachandran Vijayakumar, Ponnirul Ponmanickam
Phytofabrication Of Silver Nanoparticles Using Horse Gram (Dolichos Biflorus L.) Seed Extract And Assessment Of Its Bactericidal And Antioxidant Activities, Mahadevan Vijayalakshmi, Thangavel Rajagopal, Jeyachandran Vijayakumar, Ponnirul Ponmanickam
The Thai Journal of Pharmaceutical Sciences
The silver nanoparticles synthesized by phytofabrication method receive bigger attention due to their fascinating properties. This study deals with the green mediated synthesis of silver nanoparticles using seed extract of horse gram (Dolichos biflorus L...
Screening Of Patients Receiving Selegiline From Methamphetamine Abusers Using The Urinary Amphetamine/Methamphetamine Ratio, Nunthika Kaewpunya, Wichian Tungtananuwat, Akravudh Viriyavejakul, Patramon Yongpanich, Nantana Thong-Ra-Ar, Chanchai Hosanguan, Somsong Lawanprasert
Screening Of Patients Receiving Selegiline From Methamphetamine Abusers Using The Urinary Amphetamine/Methamphetamine Ratio, Nunthika Kaewpunya, Wichian Tungtananuwat, Akravudh Viriyavejakul, Patramon Yongpanich, Nantana Thong-Ra-Ar, Chanchai Hosanguan, Somsong Lawanprasert
The Thai Journal of Pharmaceutical Sciences
Methamphetamine (MA), the major metabolite of selegiline excreted in urine, can cause false positive interpretation of patient receiving selegiline as a MA user based on the routine non-chiral separation method. This study aims to compare the ratio of am...
Protein-Protein Docking And Molecular Dynamics Simulations Elucidated Binding Modes Of Fubi-P62 Uba Complex, Sumet Chongruchiroj, Panida Kongsawadworakul, Veena Nukoolkarn, Montree Jaturanpinyo, Wichit Nosoong-Noen, Jiraporn Chingunpitak, Jaturong Pratuangdejkul
Protein-Protein Docking And Molecular Dynamics Simulations Elucidated Binding Modes Of Fubi-P62 Uba Complex, Sumet Chongruchiroj, Panida Kongsawadworakul, Veena Nukoolkarn, Montree Jaturanpinyo, Wichit Nosoong-Noen, Jiraporn Chingunpitak, Jaturong Pratuangdejkul
The Thai Journal of Pharmaceutical Sciences
The cytosolic Fau protein, a precursor of antimicrobial peptide, composes of ubiquitin-like domain FUBI at Nterminus and ribosomal protein rpS30 at C-terminus. Fau has been important in killing of intracellular Mycobacterium tuberculosis infection throug...
In Silico Docking And Pharmacophoric Analysis Of 3-Indolyl Pyridine Derivatives Toward Cyclooxygenase-2, Sukumar Bepary, Ge Hyeong Lee, Hee Jong Lim, In Kwon Youn
In Silico Docking And Pharmacophoric Analysis Of 3-Indolyl Pyridine Derivatives Toward Cyclooxygenase-2, Sukumar Bepary, Ge Hyeong Lee, Hee Jong Lim, In Kwon Youn
The Thai Journal of Pharmaceutical Sciences
A series of 3-indolyl pyridine derivatives having anti-inflammatory activities were docked into the indomethacin binding pocket of cyclooxygenase-2 enzyme. In this in silico study, the possible orientations of the molecules in the binding site of the rec...
Integration Of Thai Traditional Medicine Into Physicians' Practice Part 1: Conditions Facilitating The Integration, Katekaew Jehso, Sanguan Lerkiatbundit, Wantanee Wiroonpanich
Integration Of Thai Traditional Medicine Into Physicians' Practice Part 1: Conditions Facilitating The Integration, Katekaew Jehso, Sanguan Lerkiatbundit, Wantanee Wiroonpanich
The Thai Journal of Pharmaceutical Sciences
The purpose of this study was to gain a greater understanding of the physicians’ experiences in the conditions facilitating physicians to integrate Thai traditional medicine (TTM) into their current practice. A qualitative grounded theory method was de...
Integration Of Thai Traditional Medicine Into Physicians' Practice Part 2: Raising Consciousness, The Process Of Integration From Physicians' Experiences, Katekaew Jehso, Sanguan Lerkiatbundit, Wantanee Wiroonpanich
Integration Of Thai Traditional Medicine Into Physicians' Practice Part 2: Raising Consciousness, The Process Of Integration From Physicians' Experiences, Katekaew Jehso, Sanguan Lerkiatbundit, Wantanee Wiroonpanich
The Thai Journal of Pharmaceutical Sciences
The main purpose of the study was to gain deeper insight on physicians’ experiences in the integration process of Thai traditional medicine (TTM) into their practice. A grounded theory method was used to gain an understanding of the core process from p...
Hptlc Method For Simultaneous Estimation Of Ramipril And Losartan Potassium In Pharmaceutical Dosage Form: Development And Validation Consideration, Darshana A. Parmar, Dinesh V. Thakkar, Rashmin B. Patel, Mrunali R. Patel
Hptlc Method For Simultaneous Estimation Of Ramipril And Losartan Potassium In Pharmaceutical Dosage Form: Development And Validation Consideration, Darshana A. Parmar, Dinesh V. Thakkar, Rashmin B. Patel, Mrunali R. Patel
The Thai Journal of Pharmaceutical Sciences
This paper describes validated high-performance thin-layer chromatography (HPTLC) methods for simultaneous estimation of ramipril (RAM) and losartan potassium (LOS) in pure powder and formulation. The HPTLC separation was achieved on an aluminum-backed l...
Anti-Platelet Aggregation Activity And Chemical Analysis Of Raw And Wine Stir-Fried Chuanxiong Rhizoma (Kot-Hua-Bua), Uthai Sotanaphun, Rataya Luechapudiporn, Prinyaporn Pradmeeteekul, Jankana Burana-Osot, Panadda Phattanawasin, Noppamas Soonthornchareonnon, Yenchit Techadamrongsin
Anti-Platelet Aggregation Activity And Chemical Analysis Of Raw And Wine Stir-Fried Chuanxiong Rhizoma (Kot-Hua-Bua), Uthai Sotanaphun, Rataya Luechapudiporn, Prinyaporn Pradmeeteekul, Jankana Burana-Osot, Panadda Phattanawasin, Noppamas Soonthornchareonnon, Yenchit Techadamrongsin
The Thai Journal of Pharmaceutical Sciences
Chuanxiong Rhizoma (CR) is the dried rhizome of Ligusticum chuanxiong Hort. It is known as Kot-HuaBua in Thai traditional medicine. Two types of CR, raw CR and wine stir-fried CR, were commercially available in traditional drugstores in Thailand. Raw CR ...
Development Thai Herbal Medicine Knowledge Base Using Ontology Technique, Wachana Tungkwampian, Anuchai Theerarungchaisri, Marut Buranarach
Development Thai Herbal Medicine Knowledge Base Using Ontology Technique, Wachana Tungkwampian, Anuchai Theerarungchaisri, Marut Buranarach
The Thai Journal of Pharmaceutical Sciences
This study proposes a method for developing a knowledge base of Thai herbal medicine by using ontology techniques and developing its application as a semantic search system. Since knowledge of Thai herbal medicine is often presented in flat knowledge and...