Open Access. Powered by Scholars. Published by Universities.®
Pharmacology, Toxicology and Environmental Health Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Pharmacology (1531)
- Medicine and Health Sciences (8)
- Pharmacy and Pharmaceutical Sciences (4)
- Animal Experimentation and Research (3)
- Medicinal Chemistry and Pharmaceutics (3)
-
- Research Methods in Life Sciences (3)
- Environmental Health (2)
- Pharmaceutics and Drug Design (2)
- Public Health (2)
- Alternative and Complementary Medicine (1)
- Bacteriology (1)
- Bioinformatics (1)
- Chemicals and Drugs (1)
- Diseases (1)
- Environmental Public Health (1)
- Environmental Sciences (1)
- Medicinal and Pharmaceutical Chemistry (1)
- Microbiology (1)
- Nanomedicine (1)
- Nanotechnology (1)
- Natural Products Chemistry and Pharmacognosy (1)
- Organic Chemicals (1)
- Other Pharmacology, Toxicology and Environmental Health (1)
- Other Pharmacy and Pharmaceutical Sciences (1)
- Other Veterinary Medicine (1)
- Physical Sciences and Mathematics (1)
- Public Health Education and Promotion (1)
- Veterinary Medicine (1)
- Keyword
-
- Antioxidant (12)
- Cytotoxicity (10)
- Stability (10)
- Zanthoxylum limonella (10)
- Chitosan (9)
-
- Validation (9)
- Indomethacin (8)
- Leguminosae (7)
- Phyllanthus emblica (7)
- Antibacterial (6)
- Antioxidant activity (6)
- Curcumin (6)
- Molecular docking (6)
- Rats (6)
- Turmeric (6)
- 2 (5)
- 4-naphthoquinone (5)
- Anti-inflammatory (5)
- Anticancer (5)
- Balsaminaceae (5)
- Docking (5)
- HPLC (5)
- Herbal medicine (5)
- Impatiens balsamina (5)
- Lung cancer (5)
- Microemulsions (5)
- Oxidative stress (5)
- Piperine (5)
- Reliability (5)
- Thailand (5)
- Publication Year
- Publication
- Publication Type
Articles 211 - 240 of 1538
Full-Text Articles in Pharmacology, Toxicology and Environmental Health
Allium Cepa Extract Attenuates Ccl4-Induced Oxidative Stress In Rat Brain, Israel Oghenevwodokohwo Okoro, Helen Ejiro Kadiri, Augusta Inegbedion
Allium Cepa Extract Attenuates Ccl4-Induced Oxidative Stress In Rat Brain, Israel Oghenevwodokohwo Okoro, Helen Ejiro Kadiri, Augusta Inegbedion
The Thai Journal of Pharmaceutical Sciences
Introduction: Carbon tetrachloride (CCl4) has been used extensively to evaluate the probable mechanisms of toxicity in experimental animals. The CCl4 induced oxidative stress in rat brain has been established. This study aim to investigate the neuro-prot.
Potentiating Role Of Palm Oil And Its Extracts In Cadmium Induced Alteration Of Amino Transferase, Patrick Chukwuyenum Ichipi-Ifukor
Potentiating Role Of Palm Oil And Its Extracts In Cadmium Induced Alteration Of Amino Transferase, Patrick Chukwuyenum Ichipi-Ifukor
The Thai Journal of Pharmaceutical Sciences
Aims: This study examined the effects of palm oil and palm oil extracts pre-treatment on the activities of serum and tissue amino transferases in acute cadmium induced toxicity. Methodology: Six experimental groups was used and group A served as the con..
Three Functional Foods From Garcinia Mangostana L. Using Low-Alpha-Mangostin Aqueous Extract Of The Pericarp: Product Development, Bioactive Compound Extractions And Analyses, And Sensory Evaluation, Pattamapan Lomarat, Primchanien Moongkarndi, Jutaphen Jaengprajak, Jutima Samer, Vimol Srisukh
Three Functional Foods From Garcinia Mangostana L. Using Low-Alpha-Mangostin Aqueous Extract Of The Pericarp: Product Development, Bioactive Compound Extractions And Analyses, And Sensory Evaluation, Pattamapan Lomarat, Primchanien Moongkarndi, Jutaphen Jaengprajak, Jutima Samer, Vimol Srisukh
The Thai Journal of Pharmaceutical Sciences
Background: As a result of the expansion of aging society worldwide, the trend in consuming healthy foods as well as functional foods for maintaining good health and preventing chronic diseases is increasing. Currently, functional foods are commercially .
The Activity Of Red Ginger Oil In Antioxidant Study In Vitro And Antihyperalgesia Effect In Alloxan-Induced Painful Diabetic Neuropathy In Mice, Fifteen Aprila Fajrin
The Activity Of Red Ginger Oil In Antioxidant Study In Vitro And Antihyperalgesia Effect In Alloxan-Induced Painful Diabetic Neuropathy In Mice, Fifteen Aprila Fajrin
The Thai Journal of Pharmaceutical Sciences
Background: Red ginger oil (RGO) was reported had the highest bio-constituent, especially its essensial oil which was important for antioxidant, than the other varieties. Chronic diabetic triggered the increasing of reactive oxygen species (ROS) which re.
Antiformation And Antimutagenic Activities Of Extracts From Pericarp And Seed Of Zanthoxylum Limonella (Dennst.) Alston, Patamawan Wipoosanapan, Keaw Kangsadalampai, Linna Tongyonk
Antiformation And Antimutagenic Activities Of Extracts From Pericarp And Seed Of Zanthoxylum Limonella (Dennst.) Alston, Patamawan Wipoosanapan, Keaw Kangsadalampai, Linna Tongyonk
The Thai Journal of Pharmaceutical Sciences
Zanthoxylum limonella aston (Z. limonella) is a popular spice in northern Thailand. It is used as a flavoring agent for certain foods. There have been studies about the biological activity of this spice including, antioxidant antimicrobial and anticancer.
Risk Assessment For Ingestion Of Off-Season Longan Stimulated By Potassium Chlorate, Theerayut Baubhom, Kannikar Chatsantiprapa
Risk Assessment For Ingestion Of Off-Season Longan Stimulated By Potassium Chlorate, Theerayut Baubhom, Kannikar Chatsantiprapa
The Thai Journal of Pharmaceutical Sciences
Off-season longans in Thailand were stimulated by potassium chlorate (KClO3). KClO3 is hazardous chemical and prohibited in food since it might cause harm to human health. This research aimed to observe for chemical effects on longan trees, and analyze t.
In Silico Analysis Of Phytochemical Compound Found In Snake Fruit (Salacca Zalacca) Peel As Anti-Aging Agent, Ermi Girsang, Chrismis Novalinda Ginting, I Nyoman Ehrich Lister, Wahyu Widowati, Satrio Haryo Benowo Wibowo, Fajar Sukma Perdana, Rizal Rizal
In Silico Analysis Of Phytochemical Compound Found In Snake Fruit (Salacca Zalacca) Peel As Anti-Aging Agent, Ermi Girsang, Chrismis Novalinda Ginting, I Nyoman Ehrich Lister, Wahyu Widowati, Satrio Haryo Benowo Wibowo, Fajar Sukma Perdana, Rizal Rizal
The Thai Journal of Pharmaceutical Sciences
Skin aging is a complicated natural phenomenon characterized by progressive loss of structural integrity and physiological function of the skin. Snake fruit (Salacca zalacca) is an important fruit crop native from Indonesia. Its waste is a potential sour.
Various Nmdar Antagonists Decrease Interferon-Alpha Induced Depression Behavior In Mice Model Of Despair, Azadeh Mesripour, Ahmad Purhasani, Valiollah Hajhashemi
Various Nmdar Antagonists Decrease Interferon-Alpha Induced Depression Behavior In Mice Model Of Despair, Azadeh Mesripour, Ahmad Purhasani, Valiollah Hajhashemi
The Thai Journal of Pharmaceutical Sciences
Introduction: Treatment with interferon-alpha (IFNa) can induce depression that is likely the result of its effect on the tryptophan–kynurenine pathway. Kynurenine passes through the blood-brain barrier and breaks to neurotoxic metabolites, such as qui...
Hepatoprotective And Choleretic Activity Of Tanacetum Vulgare Flowers Extract, Oksana Ya. Mishchenko, Kateryna O. Kalko, Marharyta Yu. Zolotaikina, Tatyana M. Gontova, Victoria V. Mashtaler, Catherine Yu. Yurchenko, Lyudmyla V. Derymedvid, Anastasia Yu. Pozdniakova
Hepatoprotective And Choleretic Activity Of Tanacetum Vulgare Flowers Extract, Oksana Ya. Mishchenko, Kateryna O. Kalko, Marharyta Yu. Zolotaikina, Tatyana M. Gontova, Victoria V. Mashtaler, Catherine Yu. Yurchenko, Lyudmyla V. Derymedvid, Anastasia Yu. Pozdniakova
The Thai Journal of Pharmaceutical Sciences
Objectives: The article presents the study of hepatoprotective and choleretic properties of Tanacetum vulgare flores dry extract (TVFDE) in vivo. Materials and Methods: The research was carried out using model of subchronic toxi? hepatitis in rats, caus..
Characterization And Potention Phytoestrogen Of Pigeon Pea (Cajanus Cajan L. Mill Sp.) On Rat Ovary, Cicilia Primiani, Pujiati Pujiati, Sutiman Sumitro
Characterization And Potention Phytoestrogen Of Pigeon Pea (Cajanus Cajan L. Mill Sp.) On Rat Ovary, Cicilia Primiani, Pujiati Pujiati, Sutiman Sumitro
The Thai Journal of Pharmaceutical Sciences
Objectives: The objective of this study to analyze the estrogenic compounds in pigeon pea seeds and the effect of the plant seeds on the development of rat ovaries. Materials and method: Liquid chromatography-mass spectrometry (MS) and gas chromatography.
Screening Of Acetylcholinesterase Inhibitory Activity In Essential Oil From Myrtaceae, Vipaporn Sareedenchai
Screening Of Acetylcholinesterase Inhibitory Activity In Essential Oil From Myrtaceae, Vipaporn Sareedenchai
The Thai Journal of Pharmaceutical Sciences
Objective: This research was to investigate acetylcholinesterase inhibitory activity of the essential oil from Myrtaceae and its components. Methods: The essential oils were extracted from fresh leave of Myrtaceae plants: Eucalyptus globulus Labill (Euca.
Physicochemical Characters And Fatty Acid Composition Of Payena Lucida Seed Oils, Penpun Wetwitayaklung
Physicochemical Characters And Fatty Acid Composition Of Payena Lucida Seed Oils, Penpun Wetwitayaklung
The Thai Journal of Pharmaceutical Sciences
Introduction: Payena lucida A.DC. seed oil has long been used as edible oil and treating various kinds of diseases as oral and topical applications in some local areas of Myanmar. Objectives: This research aimed to identify and qualify the physicochemi...
Microwave-Assisted Synthesis, In Silico Studies And In Vivo Evaluation For Antidiabetic Activity Of New Brominated Pyrazoline Analogues, Neni Frimayanti, Jasril Jasril, Ihsan Ikhtiarudin, Syilfia Hasti, Anisa Indah Reza
Microwave-Assisted Synthesis, In Silico Studies And In Vivo Evaluation For Antidiabetic Activity Of New Brominated Pyrazoline Analogues, Neni Frimayanti, Jasril Jasril, Ihsan Ikhtiarudin, Syilfia Hasti, Anisa Indah Reza
The Thai Journal of Pharmaceutical Sciences
Introduction: Pyrazolines have played crucial role in the drug discovery researches and have been used widely as an important pharmacophores or intermediet for synthesis of bioactive compounds. Objective: The aim of this work is to explore the potentia...
Association Between The Appropriate Antimicrobial Therapy And Clinical Outcomes In Patients With Sepsis, Ploylarp Lertvipapath, Chankit Puttilerpong, Peerawong Werarak, Tipa Chakorn, Nasikarn Angkasekwinai, Napakadol Noppakusomboon, Apichaya Monsomboon
Association Between The Appropriate Antimicrobial Therapy And Clinical Outcomes In Patients With Sepsis, Ploylarp Lertvipapath, Chankit Puttilerpong, Peerawong Werarak, Tipa Chakorn, Nasikarn Angkasekwinai, Napakadol Noppakusomboon, Apichaya Monsomboon
The Thai Journal of Pharmaceutical Sciences
Sepsis is leading cause of death in hospitals, but appropriate antimicrobial therapy canreduce the mortality rate and improve the clinical outcome. This prospective studyanalyzed the association between appropriate antimicrobial therapy and clinical outc.
Dna Barcoding For Authentication Of The Endangered Plants In Genus Aquilaria, Worathat Thitikornpong, Chanida Palanuvej, Nijsiri Ruangrungsi
Dna Barcoding For Authentication Of The Endangered Plants In Genus Aquilaria, Worathat Thitikornpong, Chanida Palanuvej, Nijsiri Ruangrungsi
The Thai Journal of Pharmaceutical Sciences
Agarwood is a type of wood that is used in traditional Thai medicines and has been applied in several recipes; in particular, this wood is considered as a costly resinous non-wood product. However, the morphological characteristics of the plant in the ge.
Bioactivities Of Organic Riceberry Broken Rice And Crude Riceberry Rice Oil, Vijitra Luang-In, Manatchanok Yotchaisarn, Issaraporn Somboonwatthanakul, Sirirat Deeseenthum
Bioactivities Of Organic Riceberry Broken Rice And Crude Riceberry Rice Oil, Vijitra Luang-In, Manatchanok Yotchaisarn, Issaraporn Somboonwatthanakul, Sirirat Deeseenthum
The Thai Journal of Pharmaceutical Sciences
Objectives: Riceberry broken rice (RBR) and crude riceberry rice oil (CRO) are inevitable by-products generated from organic rice process in Thailand for several tons per year with low value. The aims of this work were to determine gamma-oryzanol content.
Effects Of Age, Hydration Level, And Cosmetic Treatment On Skin Mechanical Properties Of Thai, Anyarporn Tansirikongkol
Effects Of Age, Hydration Level, And Cosmetic Treatment On Skin Mechanical Properties Of Thai, Anyarporn Tansirikongkol
The Thai Journal of Pharmaceutical Sciences
Purpose: Age and skin hydration influence skin mechanical properties. However, correlation between hydration improved by cosmetic and mechanical properties is uncertain. This study aimed to investigate the relationship between age, intrinsic skin hydrati.
Antiproliferative Effects Of Pereskiopsis Diguetii, Caralluma Speciosa And Euphorbia Ritchiei Hydroalcoholic Extract, Tossawan Jitwasinkul, Purin Charoensuksai
Antiproliferative Effects Of Pereskiopsis Diguetii, Caralluma Speciosa And Euphorbia Ritchiei Hydroalcoholic Extract, Tossawan Jitwasinkul, Purin Charoensuksai
The Thai Journal of Pharmaceutical Sciences
To date, cancers remain to be global health problem. The toxicity and the emergence of chemotherapy resistance of currently prescribed anticancer agents highlight the need for the discovery and the development of novel anticancer drugs. The previous succ.
Development And Validation Of Hptlc And Lc Ms-Ms Method For Estimation Of Terizidone In Pharmaceutical Dosage Form, Ritesh P. Bhole, Sonali Phadke
Development And Validation Of Hptlc And Lc Ms-Ms Method For Estimation Of Terizidone In Pharmaceutical Dosage Form, Ritesh P. Bhole, Sonali Phadke
The Thai Journal of Pharmaceutical Sciences
The estimation of Terizidone in pharmaceutical dosage form by using High Performance Thin Layer Chromatography was done using CAMAG HPTLC system. The separation was achieved using precoated silica gel 60 F254 aluminium plates with mobile phase Toluene: n.
Evaluating The Effect Of Donepezil On Depression And Obsessive–Compulsion Disorder In Mice Models And Proposing The Mechanism Involved, Azadeh Mesripour, Valiollah Hajhashemi, Shahrzad Rezaie
Evaluating The Effect Of Donepezil On Depression And Obsessive–Compulsion Disorder In Mice Models And Proposing The Mechanism Involved, Azadeh Mesripour, Valiollah Hajhashemi, Shahrzad Rezaie
The Thai Journal of Pharmaceutical Sciences
Introduction: Considering that donepezil (DPZ) is commonly prescribed for Alzheimer's disease patients, the aim of the present study was evaluating DPZ antidepressant effect and introducing the possible mechanism. Therefore nicotinic (mecamylamine) and m.
Anti-Hyperglycemic Effect And Subchronic Toxicity Of The Combined Extract From Sattagavata- Mathurameha -Tubpikarn Anti-Diabetic Herbal Formulae, Penchom Peungvicha
Anti-Hyperglycemic Effect And Subchronic Toxicity Of The Combined Extract From Sattagavata- Mathurameha -Tubpikarn Anti-Diabetic Herbal Formulae, Penchom Peungvicha
The Thai Journal of Pharmaceutical Sciences
The three herbal formulae (Sattagavata, Mathurameha, Tubpikarn) were prescribed to diabetic patients for a long times and they included Sattagavata for circulatory system promotion, Mathurameha for diabetics and Tubpikarn for hepatoprotection with less s.
Validated Thin-Layer Chromatography-Densitometric Method For Simultaneous Determination Of Piperine And Plumbagin In “Benjakul” Thai Polyherbal Formulation And Its Antioxidant Activities, Savita Chewchinda, Pattamapan Lomarat, Pongtip Sithisarn
Validated Thin-Layer Chromatography-Densitometric Method For Simultaneous Determination Of Piperine And Plumbagin In “Benjakul” Thai Polyherbal Formulation And Its Antioxidant Activities, Savita Chewchinda, Pattamapan Lomarat, Pongtip Sithisarn
The Thai Journal of Pharmaceutical Sciences
The purpose of this study was to evaluate antioxidant activity and quantitative analysis of piperine and plumbagin content in “Benjukul (BEN)” Thai polyherbal formulation by TLC densitometric method. BEN was recognized in the list of herbal medicinal...
Antihypercholesterol Activity Of Costus Speciosus Water Extract, Hari Susanti, Subagus Wahyuono, Ratna Asmah Susidarti, Ika Puspita Sari
Antihypercholesterol Activity Of Costus Speciosus Water Extract, Hari Susanti, Subagus Wahyuono, Ratna Asmah Susidarti, Ika Puspita Sari
The Thai Journal of Pharmaceutical Sciences
Hypercholesterol is one of cause of cardiovascular disease. Costus speciosus is known empirically as an antihypercholesterol remedy. The study was conducted to determine the effect of water extract of Costus speciosus (CS) on cholesterol blood serum leve.
Characterization Of Lactic Acid Producing Bacillus Coagulans Strains With Their Antibacterial Activity And L-Lactic Acid Production, Vasana Tolieng
Characterization Of Lactic Acid Producing Bacillus Coagulans Strains With Their Antibacterial Activity And L-Lactic Acid Production, Vasana Tolieng
The Thai Journal of Pharmaceutical Sciences
Objectives: Screening of antibacterial activity, identification, and L-lactic acid production of spore forming Bacillus isolates. Materials and methods: Fourteen Bacillus isolates were characterized based on their phenotypic characteristics and 16SrRNA .
Cost-Effectiveness Analysis Of Aripiprazole Compared With Risperidone In Treatment Of Acute Schizophrenia Patients In Thailand, Wiwat Thavornwattanayong
Cost-Effectiveness Analysis Of Aripiprazole Compared With Risperidone In Treatment Of Acute Schizophrenia Patients In Thailand, Wiwat Thavornwattanayong
The Thai Journal of Pharmaceutical Sciences
OBJECTIVES: Schizophrenia is the third leading cause of loss of life years in Thailand. Currently, aripiprazole is the latest drug for the treatment of acute schizophrenia in Thailand but its cost-effectiveness has not been studied. The purpose of this s.
A Novel Assay For Evaluation Of The Total Antioxidant Capacity (Tac) Using A Nontoxic Probe, Sirirat Panich
A Novel Assay For Evaluation Of The Total Antioxidant Capacity (Tac) Using A Nontoxic Probe, Sirirat Panich
The Thai Journal of Pharmaceutical Sciences
A novel and simple method for measuring total antioxidant capacity (TAC) was established. Herein, the new assay is based on generating the deep blue Imipramine (IMI) free radical by oxidising IMI with ammonium tetra vanadate (NH4VO3) in acid medium. Once.
In Silico Evaluation Of Molecular Interactions Between Known ?-Glucosidase Inhibitors And Homologous ?-Glucosidase Enzymes From Saccharomyces Cerevisiae, Rattus Norvegicus, And Ganc-Human, Teni Ernawati
The Thai Journal of Pharmaceutical Sciences
The aim of this study was to observe molecular interactions between alpha glucosidase inhibitor waith alpha glucosidase enzyme derived from Saccharomyces cereviseae, Rattus norvegicus and GANC-human. Therefore, they were used against four of the well-kno.
Intended High-Performance Liquid Chromatography Procedure For The Quantification Of Norfloxacin And Its Potential Impurities In Active Pharmaceutical Ingredient And Tablet Dosage Forms, Bikshal Babu Kasimala, Venkateswara Rao Anna, Useni Reddy Mallu, L. Maheshwara Reddy
Intended High-Performance Liquid Chromatography Procedure For The Quantification Of Norfloxacin And Its Potential Impurities In Active Pharmaceutical Ingredient And Tablet Dosage Forms, Bikshal Babu Kasimala, Venkateswara Rao Anna, Useni Reddy Mallu, L. Maheshwara Reddy
The Thai Journal of Pharmaceutical Sciences
Norfloxacin [NFXC] is an active pharmaceutical ingredient belongs to 4-quinolone antibacterial agent used for the prophylaxis of gram +ve and gram-ve bacterial infections. A reliable stability-indicating RP-HPLC method was developed for the separation an.
Development And Validation Of Novel Stability-Indicating High-Performance Liquid Chromatography Method For The Determination Of Miglitol In Pharmaceuticals, Kanakapura Basavaiah, Nagaraju Rajendraprasad
Development And Validation Of Novel Stability-Indicating High-Performance Liquid Chromatography Method For The Determination Of Miglitol In Pharmaceuticals, Kanakapura Basavaiah, Nagaraju Rajendraprasad
The Thai Journal of Pharmaceutical Sciences
A reversed phase high performance liquid chromatographic (RP-HPLC) method for the determination of miglitol (MGL) in pharmaceuticals is presented. The assay was performed on a Phenomenex Luna C18 (150 × 4.6 mm; 5µm particle size) column using phosphate...
Quantitative Structure–Activity Relationship Modeling Of S-Triazines And 2-Arylpyrimidines As Selective Pde4b Inhibitors, Anand Gaurav, Gabriel Akyirem Akowuah, Choo Shiuan Por
Quantitative Structure–Activity Relationship Modeling Of S-Triazines And 2-Arylpyrimidines As Selective Pde4b Inhibitors, Anand Gaurav, Gabriel Akyirem Akowuah, Choo Shiuan Por
The Thai Journal of Pharmaceutical Sciences
A QSAR analysis was conducted on a series of 2-arylpyrimidine and s-triazine derivatives as selective PDE4B inhibitors. Primary objective of the study is to develop predictive QSAR models for s-triazines and 2-arylpyrimidines as selective PDE4B and to id.