Pharmacology, Toxicology and Environmental Health Commons^™

Determination Of The Ld-50 Level For 2,4-D On Wild Type Culex Pipiens Mosquito Larvae In Illinois, William H. Ettinger

Masters Theses

The LD-50 levels for 2,4-D and Ronnel were determined and compared on the larvae of Culex pipiens Linneaus mosquitoes. The World Health Organization technique for the 24 hour bioassay was employed. Ronnel served as an indicator of susceptibility to pesticides and it was found that 2,4-D is toxic to mosquito larvae with an LD-50 level of 1.95 p.p.m. It was also found that a concentration of 20 p.p.m. ethanol or greater causes lethality in the larvae.

Mercury, Dieldrin, Ddt, Dde, And Pcb Levels In Tissues From Fish And Wildlife In Utah, Fred A. Smith

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Fish and wildlife were randomly sampled in Utah from pre-selected x areas and analyzed for levels of total mercury, dieldrin, DDT, and DDE. Levels were well within consumptive tolerance or guideline limits except for mercury levels of fish in Willard Bay Reservoir. PCB's were also identified in a large proportion of samples.

None of the chukars, 6 percent of the pheasants, 4 percent of the waterfowl, and none of the fish sampled, excluding Willard Bay Reservoir, were above the 0.5 ppm guideline level for mercury established by the Food and Drug Administration. Seventy-seven percent of the fish sampled from Willard …

Absorption, Translocation And Metabolism Of 1,3-Dichloropropene In Selected Plants, David L. Berry

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The absorption, translocation and metabolism of 1,3-dichloropropene (a soil fumigant) in bush beans, tomato and carrot was studied under growth chamber and greenhouse conditions using solution culture, vermiculite and sand. Absorption was monitored using gas chromatographic analysis and isotope techniques. Plants were shown to absorb a maximum amount of dichloropropene by 24 to 48 hr from solution culture and vermiculite. The plant absorbed and translocated 1,3-dichlorpropene-¹⁴C-U readily to aerial parts of the plant.

Bush beans, tomatoes and carrots absorbed and translocated 3-chlorallyl alcohol-¹⁴C-U from solution culture and vermiculite. Levels of 3-chloroallyl alcohol reached maximum at 24 …

A Study Of Organochlorine Insecticides In Freshwater Crayfish -- Analytical Problems And Biomonitoring Survey, Robert C. Vanderjack

Masters Theses

Crayfish were collected from 3 sites on Polecat Creek, Coles County, Illinois in early spring, early summer, and late summer of 1972. Pesticides were extracted from the crayfish tissue in a one step procedure utilizing a Florisil elution column. Analysis was by electron capture gas chromatography. Pesticide residues in the nannogram range were analyzed and background contamination was an important consideration. Sources of background contamination were investigated and teflon stopcocks, Florisil, and residues on “cleaned” glassware were found to be major contamination sources. Distilled water used in flushing glassware should also be considered a potential contamination source.

Aldrin, dieldrin, and …

Morphological And Physiological Effects Of 2,4-D On Gram-Negative And Gram-Positive Bacteria, John H. Rupnow

Masters Theses

Manometric, spectrophotometric, photomicrographic and quantitative biochemical techniques were employed to determine the morphological and physiological effects of 2,4-D on Gram-positive and Gram-negative bacteria.

The growth and motility of Gram-positive bacteria appeared to be more adversely affected than the growth and motility of Gram-negative species. The terminal oxidation, lysis, and chain length of both Gram-positive and Gram-negative bacteria did not appear to be affected by the concentrations used. The average cell size of both Gram-positive and Gram-negative bacteria was observed to increase after exposure to 1000 ppm 2,4-D. The normal leakage of amino acid and ultraviolet light absorbing cell constituents appeared …

Poison Plants Of Western Australia : The Toxic Species Of The Genus Gastrolobium And Oxylobium., T E H Aplin

Bulletins 4000 -

The toxic species of the genera Gastralobium and Oxylobium are a unquie group of poison plants whch have cause considerable economic loss to stock-raisers in Western Australia ever since early days of settlement.

The Effect Of The Herbicide Glyphosate On The Growth Of Selenastrum Capricornutum, Judith Susan Eisen

Undergraduate Honors Capstone Projects

The herbicide glyphosate (MON-0139), an isopropylamine salt of N- (phosphonemethyl)glycine, was tested to determine its effects on the growth of the fresh water green alga Selenastrum capricornutum. Experiments were carried out to determine algicidal, algistatic, and inhibitory concentrations of the compound.

Concentrations from 5 ppm to 1000 ppm were inhibitory to the growth of the alga, but the effects were algistatic, rather than algicidal. At concentrations from 0.1 ppm to 1.0 ppm the growth of the alga was stimulated by the presence of the herbicide, while at concentrations from 0.001 ppm to 0.05 ppm the effects of the herbicide were …

The Interaction Of Promazine With Selected Macromolecules And A Membrane Utilizing Absorption And Emission Spectroscopy, Jess D. Keeler

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The association of promazine-HCl with bovine serum albumin, ammonium detergent micelles, and hemoglobin-free-rabbit-erythrocyte membranes were measured using the changes in the absorption and the emission of the interactants plus the fluorescent probe 1-anilino-8-naphthalene sulfonate. The binding of a promazine to serum protein and membrane did not alter the emission of the drug. However, the binding did produce a measurable quenching of the membrane and protein fluorescence. The quenching reaction was pH sensitive for both the protein and the membrane. Promazine binding to serum protein produced a hyperchromic change in the drugs absorption spectrum which paralleled the quenching reaction. The binding …

Effect On Bees Of Insecticides Used On Rape, A C. Kessell

Journal of the Department of Agriculture, Western Australia, Series 4

Rapeseed could provide beekeepers in Western Australia with a valuable new honey crop—hut insecticidal spraying of rape at flowering time is a potentially serious threat to most commercial beekeepers.

There are indications that insect pollination may improve rapeseed yields, so both growers and beekeepers could gain from a co-operative approach to the problem. Spraying after sundown and preventing spray drift to nearby apiaries should avoid most losses.

Preliminary Observations On The Effects Of Treflan To Fishes, P. Bradley Latvaitis

Masters Theses

Treflan E.C. is a selective, preemergence, soil incorporated herbicide. Preliminary tests were made to evaluate its effects at concentrations of 0.75, 1.275 and 1.8 p.p.m. on twenty species of fresh water fishes in the laboratory. The herbicide was proven to be a powerful fish toxicant. Centrarchus, Cichlasoma centrarchus, was the most resistant fish tested, while Bluegill, Lepomis macrochirus, was among the least resistant. Treflan E.C. decomposes and degrades rapidly. It was also found to interact with plastics. Further studies are necessary to provide a complete investigation of the effects of Treflan on Fishes.

Poison Sedge Can Kill Stock, M E. Nairn, T. E. H. Aplin, D. S. Petterson, A. J. Brighton

Journal of the Department of Agriculture, Western Australia, Series 4

POISON SEDGE was first suspected of being toxic to livestock in Western Australia nearly 80 years ago.

Sudden deaths of sheep grazing areas on which poison sedge grew have been reported from many regions from Geraldton to Scott River.

This article reports a case of poisoning in the field, and the experimental reproduction of poison sedge toxicity in pen-fed sheep.

Chemical Control Of Eucalypts : Standing Timber, Stumps, Sucker Regrowth, Geoffrey A. Pearce

Journal of the Department of Agriculture, Western Australia, Series 4

The eucalypt is particularly well adapted to withstand long periods without rain. The characteristics which make this possible also make the tree difficult to kill, without removing the stump and part of the root system.

Industrial Pollution In Coles County, Illinois, Michael William Conlin

Masters Theses

The Anaconda American Brass Company at Mattoon, Coles County, Illinois was found to discharge waste containing excessive amounts of copper, hexavalent chromium, sulfates, acids, and alkalies. These wastes were found to enter an agricultural field tile system and to emit at the Shellhammer tile where they entered a small unnamed creek, a large pond along Interstate 57, and Riley Creek.

Tests of the Shellhammer tile and Anaconda American Brass Company effluent were conducted from March, 1970 thru May, 1971. Maximum concentrations determined were as follows: (1) copper -- 15.5 ppm; (2) hexavalent chromium -- 1.5 ppm; (3) pH -- range …

Effects Of Controlled Atmosphere Storage On Specific Biochemical Changes In Apricot And Peach Fruits, Bartley Norman Wankier

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The effects of controlled atmosphere storage vs conventional refrigerated storage on the metabolism of Moorpark and Large Early Montgamet apricot and Elberta peach fruits were studied. The controlled atmospheres studied were 0.0 percent CO₂-5.0 percent O₂; 2.5 percent CO₂-5.0 percent O₂; 5.0 percent CO₂-2.5 percent O₂; 7.5 percent CO₂-5.0 percent O₂; as compared to conventional refrigerated storage. Nitrogen percent was assumed to be the difference between the total CO₂ and O₂ content minus 100.

Fruits were periodically removed from the storage and …

A Comparative In Vitro Metabolic Study Of Certain Pesticidal Phenyl N-Methyl-Carbamates, Larry A. Wheeler

Loma Linda University Electronic Theses, Dissertations & Projects

Two critical parameters in the evaluation of the toxicological hazards of the use of carbamate pesticides are: (1) a rapid, sensitive, and precise analytical method of identification of the carbamate and its metabolites; and (2) their metabolism. A method in this study was developed whereby various carbamates and their metabolites could be chromatographed in the gaseous phase. Also, a comparative in vitro study of 15,000 g liver supernatants from human, rat, and dog was performed. Additional tissues investigated for metabolic activity toward the carbamates, Zectran and Mesurol, were kidney (from the dog only) and various blood fractions (red blood cells, …

Estamos Contaminando El Agua Del Mar, Aldemaro Romero Jr.

Publications and Research

No abstract provided.

Brisket Disease: Influence Of Hypoxia And An Induced Calcium-Potassium Imbalance On The Mineral Composition Of Blood, Heart, Liver, Kidney, And Bone, David Eugene Bailey

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Brisket disease, an affliction of cattle, is important because of: (1) economic losses, (2) similarities to chronic mountain sickness in humans, and (3) the provision of experimental animals for cardiac research. In afflicted cattle, right cardiac ventricular hypertrophy and dilatation occur and are manifestations of attempted compensation for reduced alveolar oxygen by increasing pulmonary circulation.

Geographic variations in occurrence of brisket disease in Utah indicate that hypoxia is not the sole causative factor. From the findings that afflicted cattle exhibit hypocalcemia and hyperkalemia, and the disease occurs most commonly in wet meadowland environments where potassium is high and calcium low …

Brisket Disease: Elemental And Oxalate Contents Of Cattle Forages On Two Utah Cattle Allotments, Raga Hafez I. Abaza

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

It was hypothesized that the hypocalcemia, hyperphosphoremia, hyperkalemia and the mild hypochromic microcytic anemia which existed in cattle afflicted with brisket disease could be due, at least in part, to nutritional disturbances. A chemical composition study was made of seven monocotyledonous plant species that comprise a major part of the diet and nine dicotyledonous plant species consumed by cattle and known or suspected of being poisonous. The plants analyzed were collected from two cattle grazing allotments, 7-mile and UM, in the Fishlake District, Fishlake National Forest, Utah, where brisket disease incidence is high. In each species the percentages on dry …

Poison Plants Of Western Australia : The Toxic Species Of The Genera Gastrolobium And Oxylobium : Prickly Poison And Bullock Poison, T E H Aplin

Journal of the Department of Agriculture, Western Australia, Series 4

PRICKLY POISON is one of the most widely distributed and one of the most variable of species of the genus Gastrolobium.

Is Your Farm A Haven For Grain Pests, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

Overseas markets insist that the grain they buy must be in sound condition and free of insect pests.

Keep your farm free of stored grain pests and you will help to protect our export markets and reduce the cost of treatment that you and your neighbours will bear.

Poultry : Toxic Factors In Protein Supplements, D F. Hessels

Journal of the Department of Agriculture, Western Australia, Series 4

The toxic effect of low quality and/or stale protein supplements can be a problem in the poultry industry.

This article describes trials carried out to assess their importance in Western Australia.

Wallaby Control In The Kimberleys, C D. Gooding

Journal of the Department of Agriculture, Western Australia, Series 4

EXPERIMENTS aimed at controlling sandy wallabies along the Fitzroy River frontage were started in 1952 by officers of the Agriculture Protection Board.

This work was undertaken in response to requests for assistance from some of the station owners and managers between Derby and Fitzroy Crossing.

Interbasin Movement Of Ground Water At The Nevada Test Site, Isaac J. Winograd

Publications (WR)

The present paper presents hydraulic evidence for the interbasin circulation of ground water through carbonate rocks of Paleozoic age at the Nevada Test Site. An integral part of this evidence is the discovery that aquifers in alluvium and tuff, formerly thought to be the principal aquifers at the Test Site, are semiperched above a thick tuffaceous aquiclude that separates them from the carbonate rocks.

This paper is based on one of the studies being made by the Geological
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Dingo And Fox Baits, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

THE Vermin Control Section of the Agriculture Protection Board has devised an effective method of preparing poison for impregnating dingo and fox baits. The method is recommended where it is not convenient to use commercial 1/2 grain strychnine tablets.

Control Of The Emu, C D. Gooding, J. L. Long

Journal of the Department of Agriculture, Western Australia, Series 4

Vermin research officers C. D. GOODING and J. L LONG give the latest recommendations for control of the emu, based on a series of observations and poisoning experiments in the northern wheatbelt.

An Improved Method Of Utilising Strychine In The Preparation Of Dingo And Fox Baits, L A. Harrison

Journal of the Department of Agriculture, Western Australia, Series 4

AT present dingo and fox baits are made from fat or other material attractive to the animal to be poisoned, into which is inserted either alkaloid or soluble strychnine.

Vermin Symposium Report : Wanted : A New Approach To Rabbit Control, A R. Tomlinson

Journal of the Department of Agriculture, Western Australia, Series 4

THE main reason why rabbits have not increased as rapidly as their amazing capabilities might have led people to expect has been a series of years not suitable for full breeding.

This has been more important than myxomatosis and "1080". This was one of the thoughts taken away by those who attended the rabbit control symposium held in Perth recently.

Toxic Annuals In Horticulture, Robert Dunlop Royce

Journal of the Department of Agriculture, Western Australia, Series 4

THE number of poisonous shrubs and trees that are grown in gardens is very great, and several of these species have been discussed in detail.

It is probable that few people realise just how many of the commonest garden plants are in some way or under some circumstances, likely to contain a toxic principle.

Furthermore, this is not confined to the longer lived plants, but it applies equally to the annual plants, both summer growing and winter growing.

Wild Dog Control In The North-West, R J. Fraser

Journal of the Department of Agriculture, Western Australia, Series 4

BECAUSE of its sparsely-settled condition, the North-West of Western Australia is almost an ideal breeding-ground and hunting-ground for wild dogs.

Even the best of the pastoral country is but thinly populated and there are large areas of rugged country which is seldom traversed by white men.

Rats And Mice And Their Control, C D. Gooding, J. L. Long

Journal of the Department of Agriculture, Western Australia, Series 4

BEFORE colonisation by the white man, Australia contained over 50 species of rats and mice.

Although several of these native species have been known to breed to plague proportions they are normally slower breeders than the introduced species.

Once settlement had been established on our shores it was only a matter of time before the introduction of more of these pests, occurred probably from the British Isles.