Pharmacology, Toxicology and Environmental Health Commons^™

Western Rock Lobster Fishery Harvest Strategy And Decision Rules Framework Proposals, Department Of Fisheries

Fisheries Management Papers

No abstract provided.

The Malawi Project: From Conventional To Holistic Decision Making, Grace Wetmore

Animal Science

How the Cal Poly Malawi Appropriate Technologies Team, and other development groups, can use Holistic Management to aid developing countries in an effort towards a sustainable future.

Curing Nature-Deficit Disorder: How Environmental Education Helps Kids Learn, Jamie Leigh Langley

Mahurin Honors College Capstone Experience/Thesis Projects

Walk into any public school and talk with the children about their experiences in nature and you will begin to see a pattern. Children have made few connections with the world around them. They do not spend much time outdoors and the time they do spend outdoors is not spent interacting directly with nature. Why does this matter? Look at these same kids and you will see another pattern emerging: Attention-Deficit Disorder, depression, obesity, emotional problems, etc. While not all of these problems are directly caused by a lack of interaction with the natural world, current research shows that there …

The Amphipod Orchomenella Pinguis — A Potential Bioindicator For Contamination In The Arctic, Lis Bach, Valery E. Forbes, Ingela Dahllöf

Valery Forbes Publications

Indigenous organisms can be used as bioindicators for effects of contaminants, but no such bioindicator has been established for Arctic areas. Orchomenella pinguis is a benthic amphipod, ubiquitous in the Arctic and can be found in high numbers. We collected O. pinguis at sites with different contamination levels. Population characteristics (body length distribution, average dry weight and amphipod organic content) were related to sediment contaminant concentrations, in order to identify suitable endpoints for using this species as a bioindicator. We show that O. pinguis was prevalent in both clean and contaminated areas, easy to sample and that its population characteristics …

Application Of Multiple Mass Spectrometric Techniques In The Isolation, Determination And Characterisation Of The Marine Toxins; Azaspiracid, Keith O'Callaghan

Theses

The Azaspiracids are a class of polyether marine biotoxins that present a significant health risk to consumers of shellfish. Since their discovery in the late 1990s several human intoxications have been reported, and traced to Irish shellfish farms resulting in closures or harvest rejections. As such incidents involving azaspiracid shellfish poisoning have a major socio-economic impact on communities that rely on shellfish farming revenues.

Recent evidence suggests that azaspiracid poisoning events may become more commonplace. With this increased risk the understanding of azaspiracids mode of action and biological targets becomes crucial. To support these endeavours effective analytical methods need to …

Landholder Information For The Safe Use And Management Of Strychnine For Emu Control, Renee Donovan, David Goodall

Biosecurity published reports

Farmnote 34/2003 - Guide to safe use of strychnine poison for emu control included.

Strychnine is a highly poisonous substance that is used in Western Australia for the control of Wild Dogs and Emus. Its use is restricted by law.

This manual outlines your roles and responsibilities in regard to Strychnine use for emu control. In particular this manual outlines the essential information you need to know in regard to:

• The legislative requirements for Strychnine control in Western Australia
• The properties and mode of action of Strychnine
• How to apply to have a strychnine emu baiting program carried out on …

Landholder Information For The Safe Use And Management Of 1080, Renee Donovan, David Goodall

Biosecurity published reports

This manual outlines your roles and responsibilities for using and managing 1080. In particular this manual outlines the essential information you need to know in regard to:

• The legislative requirements for 1080 control in Western Australia
• The properties and mode of action of 1080
• How to lodge an application to lay 1080 baits How to safely store and transport 1080
• The procedures and notification required to carry out a baiting proposal
• Personal safety, identifying signs of poisoning & effecting appropriate first aid treatment
• Your responsibilities for notifying DAFWA and the Police of any accidents or incidents
• Methods for evaluating the …

Landholder Information For The Safe Use And Management Of Strychnine For Wild Dog Traps, Renee Donovan, David Goodall

Biosecurity published reports

Farmnote 33/2003 - Guide to the safe use of strychnine for jawed traps is included.

Strychnine is a highly poisonous substance that is used in Western Australia for the control of Wild Dogs and Emus. Its use is restricted by law.

This manual outlines your roles and responsibilities for using and managing Strychnine for Wild Dog control. In particular, this manual outlines the essential information you need to know in regard to:

• The legislative requirements for Strychnine control in Western Australia
• The properties and mode of action of Strychnine « How to lodge an application to use Strychnine
• How to …

Accumulation Of Phycotoxins In The Mussel Mytilus Galloprovincialis From The Central Adriatic Sea, Maja Pavela-Vrančić, Ivana Ujević, Živana Ninčević Gladan, Ambrose Furey

Physical Sciences Publications

Surveys of DSP (Diarrheic Shellfish Poisoning) toxin profiles in the mussel Mytilus galloprovincialis from coastal waters of the central Adriatic Sea, over the years 1995 to 2001, demonstrate that incidents of shellfish toxicity in this area are dominated by the occurrence of okadaic acid (OA) and a PTX derivative, 7-epi-pectenotoxin-2-seco acid (7-epi-PTX-2SA). Toxin composition and the relative ratio of toxic components in shellfish is in correlation with the occurrence of DSP producing organisms from the Dinophysis species along with Prorocentrum micans and Lingulodinium polyedrum. The occurrence of D. sacculus shortly before the appearance of OA in shellfish implicates its possible …

Differential Expression Of Immune Response Genes In Steller Sea Lions (Eumetopias Jubatus): An Indicator Of Ecosystem Health?, Lizabeth Bowen, Brian Aldridge, Kimberlee Beckmen, Tom Gelatt, Lorrie Rea, Kathy Burek, Ken Pitcher, Jeffrey L. Stott

United States Department of Commerce: Staff Publications

Characterization of the polygenic and polymorphic features of the Steller sea lion major histocompatibility complex (MHC) provides an ideal window for evaluating immunologic vigor of the population and identifying emergence of new genotypes that reflect ecosystem pressures. MHC genotyping can be used to measure the potential immunologic vigor of a population. However, since ecosystem-induced changes to MHC genotype can be slow to emerge, measurement of differential expression of these genes can potentially provide real-time evidence of immunologic perturbations. MHC DRB genes were cloned and sequenced using peripheral blood mononuclear leukocytes derived from 10 Steller sea lions from southeast Alaska, Prince …

A Switch From Polyandry To Serial Monogamy: Results From A Three Year Tagging Study Of Horseshoe Crabs In Long Island Sound, Jennifer Mattei Ph.D., Paul Goodell, Christine Depierro, Meghann Burke

Biology Faculty Publications

Part of an ongoing population study of the North American Horseshoe Crab, Limulus polyphemus, in Long Island Sound was completed during the 2003 – 2005 spawning seasons at Milford Point, in Milford, CT. Horseshoe crabs range more widely throughout Long Island Sound than expected and exhibit weak site fidelity. Animals originally tagged in Milford were found as far west as Stamford and as far east as Clinton, CT. during the 3 year study. Out of 522 female horseshoe crabs tagged in 2004 only 4 came back to spawn again at Milford Pt. in 2005. The sex ratios of tagged and …

Differences In Pah Tolerance Between Capitella Species: Underlying Biochemical Mechanisms, Lis Bach, Annemette Palmqvist, Lene Juel Rasmussen, Valery E. Forbes

Valery Forbes Publications

The polychaete Capitella capitata consists of a species complex within which differences in tolerance to tox­icants have been observed. For example, it has been shown that Capitella sp. S is more sensitive (e.g., in terms of survival, growth and reproduction) to PAH and other stressors than the more opportunistic Capi­tella sp. I, which is able to take up and biotransform the PAH fluoranthene (Flu). In the present study, an in­vestigation was performed to examine whether differences in tolerance between Capitella species sp. I and sp. S are due to differences in biotransformation, measured as the amount of Flu-metabolites produced by …

Risk And Consequence Analysis Focused On Biota Transfers Potentially Associated With Surface Water Diversions Between The Missouri River And Red River Basins, Greg Linder, Ed Little, Lynne Johnson, Chad Vishy, Bruce Peacock, Heather Goeddecke

United States Geological Survey: Publications

Section 1 provides a brief overview of the project, including a cursory summary of the history of the “Garrison Diversion” and how that history relates to this work focused on the analysis of risks and consequences potentially associated with interbasin biota transfers. The present study was initiated under the auspices of the Dakota Water Resources Act (DWRA) of 2000, which directed the Secretary of the Interior to conduct a comprehensive study of the water quality and quantity needs of the Red River Valley and the options for meeting those needs. As such, the Bureau of Reclamation (Reclamation) requested technical support …

Environmental Guidelines For New And Existing Piggeries, A Latto, John Noonan, R. J. Taylor

Bulletins 4000 -

These guidelines apply to the management of Western Australia piggeries in Western Australia, including intensive Growing pigs under intensive conditions where the and extensive operations, straw-based housing and animals spend their entire life cycle indoors, is an combinations of these (otherwise referred to as semi- important part of the Western Australian and intensive housing).

Pfiesteria Piscicida And Dinoflagellates Similar To Pfiesteria, Harold G. Marshall

Virginia Journal of Science

Pfiesteria pisiccida is a microscopic, unicellular organism that is classified as both a mixotrophic and heterotrophic dinoflagellate, which has been associated with both fish deaths and a cause of human illness (Burkholder et al., 1992; Glasgow et al., 1995; Burkholder and Glasgow, 1997). This species possesses a complex life cycle that includes motile forms (e.g. zoospores, gametes, amoebae) and a cyst stage that may remain dormant in the sediment (Burkholder et al., 1995b). Pfiesteria piscicida is known to have toxin and non-toxin producing populations, where cyst transformation into the toxic motile zoospores may be initiated by the presence of certain …

The Relationship Between Ohio River Bass Tournament Success Rates, Forage Fish Abundance And Environmental Conditions, Jeffrey V. Ginger

Theses, Dissertations and Capstones

Due to increasing pressure from Ohio River bass anglers with regard to decreasing catch rates in 1981,1990, and 1997, the West Virginia Division of Natural Resources (WVDNR) initiated a study of black bass populations. The Ohio River Valley Water Sanitation Commission (ORSANCO), in conjunction with state and Federal agencies, has collected population data on Ohio River fishes at lock chambers and has measured various water quality parameters since 1957. That data coupled with Ohio River bass tournament data collected by the DNR since 1975 and other fishery data sets provided a historic look into the variability of angler success. These …

Acidic Marine Biotoxins Implicated In Diarrhetic Shellfish Poisoning, Eoin P. Carmody

Theses

An okadaic acid (OA) etiology has been demonstrated for most outbreaks of diarrhetic shellfish poisoning (DSP) in Europe, An isomer of OA, dinophysistoxin-2 (DTX-2), has recently been found in Irish waters and, in 1991 and 1994, was the major toxin during prolonged infestations in cultivated mussels (Mytilus edulis) along the south-west coast of Ireland.

The OA class of DSP toxins have been analysed by HPLC using modified versions of three established fluorescent derivatisation methods. A ‘dual tag’ method for the confirmation of specific toxins has also been developed.

Survey work has been carried out over the past four years on …

Cerebral Microcirculatory Effects Of Maturation, Scott R. Elliott

Loma Linda University Electronic Theses, Dissertations & Projects

The present studies demonstrate that in the second (2B) and fourth (4B) branches of newborn and adult sheep middle cerebral arteries, 5-HT2 serotonergic receptors mediate contractile responses to serotonin and that alpha-1 adrenergic receptors mediate contractile responses to norepinephrine. In addition, tissue sensitivity to 5-HT and NE decreases significantly with maturation, but does not vary with branch order. These age-related changes were associated with a decrease in affinity and maximum response in 2B and 4B segments of 5-HT and NE contracted arteries, respectively. Norepinephrine and 5-HT occupancy at the pD₂ rose significantly in 2B segments, but did not change …

The Accumulation And Run-Down Of Dieldrin In Wethers Grazed On Paddocks Previously Treated With Dieldrin, Tony Albertsen, Roy Casey, Keith Croker

Journal of the Department of Agriculture, Western Australia, Series 4

In mid 1987, the organochlorines (O/Cs) DDT, dieldrin, heptachlor and chlordane were deregistered for agricultural and horticultural use in Australia. These chemicals had been used widely, and land on several hundred Western Australian farms, particularly where potatoes had been grown, was contaminated with chemical residues. Livestock grazing pastures on such land was also contaminated, and our beef exports were threatened. In 1988, the Western Australian Department of Agriculture started a two-year project to collect information from sheep which were grazed on land that had previously been treated with O/Cs, particularly dieldrin. The levels of O/Cs in body and wool fats …

Copper Accumulation By Gizzard Shad (Dorosoma Cepedianum) In The Charleston Side Channel Reservoir, Mark T. Christ

Masters Theses

Exposure to trace heavy metals is being extensively studied in relation to their adverse and toxic effects on organisms. Processes affecting compartmentalization, biogeochemical cycling, and transport of trace metals in ecological systems must be elucidated if the impact of trace metal releases on biota are to be understood. Because elemental cycles are often closely linked to hydrologic processes, freshwater and marine systems serve as both vectors and sinks for trace metals in the environment. The regular addition of a heavy metal into an aquatic ecosystem will undoubtedly increase its persistance for availability to the existing biota. Once in the environment, …

Fisheries Report No 74 - Marine Resources Map Of Western Australia- Part 2 - The Influence Of Oil On Marine Resources And Associated Activities With An Emphasis On Those Found In Western Australia, H. E. Jones

Fisheries Research Reports

Part 1 of the text accompanying the marine resources maps dealt with the resources and the morphological, hydrological and meteorological characteristics of the Western Australian coastal environment. This subsidiary part is concerned with the effects of oil on marine resources and associated commercial and recreational activities.

Accounts of oil on the seas due to natural seepages appeared in Europe in the sixteenth century on the return of Spanish and Portuguese ships from voyages to the Americas. One of the earliest reports of oil pollution from a man-made source was in 1754 when leakages from wooden petroleum barges were prevalent in …

Seasonal Variation In Population Location Of The Galapagos Tortoise, Geochelone Elephantopus Vandenburghi, On Volcan Alcedo, Isabela Island, Galapagos Archipelago, Kent R. Beaman

Loma Linda University Electronic Theses, Dissertations & Projects

Twenty tortoises, 10 adult males and 10 adult females, were tagged with radio transmitters. Numbers were painted on each carapace to aid in visual sighting. The tortoises were released, and their movement was monitored over a one year period.

The percent recovery of tagged tortoises along with the numbers of non-tagged tortoises counted in sections of the study area, were used to determine tortoise population movement and location.

Weather data were collected and observations were made concerning the vegetation. These observations were compared with those from previous studies to see what impact seasonal climatic conditions and food availability had on …

Toxicological Studies On Aquatic Contaminants Originating From Coal Production And Utilization: The Induction Of Tolerance To Silver In Laboratory Populations Of Fish And The Chronic Toxicity Of Nickel To Fish Early Life Stages, Wesley J. Birge, Jeffrey A. Black, James F. Hobson, Albert G. Westerman

KWRRI Research Reports

Aquatic toxicity studies were performed on two important coal-derived contaminants, silver and nickel. Silver was investigated with regard to metal-induced tolerance in laboratory populations of the fathead minnow (Pimephales promelas). Fish were exposed to acute silver concentrations following acclimation to sublethal exposures of this metal. Based on median lethal times (LT50), animals which had received 14 days prior exposure to 1.5 and 15 μg Ag/L were three to four times more resistant to silver than were previously unexposed organisms. This metal-induced resistance was not a sustained response. After organisms which had been acclimated to 15 μg/L had been transferred to …

Lead Poisoning Of Sandhill Cranes (Grus Canadensis), R. M. Windingstad, S. M. Kerr, L. N. Locke, J. J. Hurt

Papers in Ornithology

Two wild and two captive sandhill cranes (Grus canadensis) were diagnosed by National Wildlife Health Laboratory personnel as having died from lead toxicity. Ingestion of lead fishing weights by the wild cranes and of unspent .22 caliber shell cartidges by the captive cranes were responsible for these deaths. One crane force-fed lead pellets showed an increase of blood lead levels from 0.77 ppm to 23.8 ppm (wet weight) just before its death 15 days following exposure. Liver lead concentrations of sandhill cranes dying of causes other than lead toxicity are presented.

How Rabbit Poisoning Methods Work, S H. Wheeler

Journal of the Department of Agriculture, Western Australia, Series 4

While the "rabbit plauges" of the past are a distant memory for most farmers, rabbit numbers must still be controlled in many parts of Western Australia. Rabit control techniques rely heavily on poisoning, which given the right conditions can kill a high percentage of rabbits at risk.

Recent research by the Agricultural Protection Board has been aimed at determining how different poisons, baits and poisoning methods work. By knowing in detail how each method works and what influences its results, we can choose the best control method for a particular place and time, avoid costly failures, and increase the effectiveness …

1080 : A Selective Poison For Pests, D R. King

Journal of the Department of Agriculture, Western Australia, Series 4

Since the 1960s, the control programmes for rabbits and dingoes in Western Australia have relied heavily on the use of sodium monofluoroacetate, more commonly known as compound 1080. Large quantaties are used each year as it is a valuable substance for the control of vertebrate pests.

Once in the animal's body 1080 is converted to fluorocitrate, a poison which is highly toxic to most mammals. Fluorocitrate blocks the Krebs cycle, a fundamental pathway of energy exchange in animals and plants. The animal dies as a result of damage to the heart, or to the brain and central nervous system, or …

The Induction Of Tolerance To Heavy Metals In Natural And Laboratory Populations Of Fish, Wesley J. Birge, William H. Benson, Jeffrey A. Black

KWRRI Research Reports

Aquatic toxicity studies were performed on two natural populations of fathead minnows. One group of organisms was taken from a metal-contaminated flyash pond associated with a coal-fired power plant and the other group was collected from relatively uncontaminated hatchery ponds. Acute tests indicated that flyash pond fish were significantly more tolerant to cadmium and copper than were hatchery fish. At an exposure concentration of 6.0 mg Cd/L in moderately hard water, the median period of survival for flyash pond fish was 50.0 hr compared to 6.8 hr for hatchery fish. Both groups of organisms were about equally sensitive to zinc. …

Mast Cell Histamine Release Induced By Portuguese Man-Of-War (Physalia) Venom, A. Lester Flowers

Loma Linda University Electronic Theses, Dissertations & Projects

Richet and Portier studied the immunization of dogs against attenuated toxic extracts of the sea anemone and showed that, when given secondary injections of sublethal amounts of native toxic extracts, the dogs experienced severe pruritus and insensitivity followed by death. They called this increased sensitivity to the toxins, anaphylaxis. Richet and Portier, and later Jacques and Schachter, and Uvnäs also studied the direct pruritic and histamine releasing effects of cnidarian (e.g. Physalia, Actinia, Cyanea), toxic extracts. While the anaphylactic effect, discovered by Richet and Portier, has been extended by numerous studies to provide the foundation of our current knowledge of …

Leptophos Metabolism In The Rat: An In Vivo Study Of Oxidative Versus Conjugative Modes Of Metabolism, David Richard Hampson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The objectives of this research were to examine the metabolism in vivo of the pesticide leptophos in the rat under normal conditions and during inhibition of the mixed-function oxidases and during depletion of glutathione. Glutathione is a cofactor in the conjugation reactions of the glutathione-S-transferases. Both the mixed-function oxidase system and the glutathione-S-transferases have been shown to be important in the biotransformation of other organophosphate pesticides.

Urinary metabolites of leptophos were extracted, derivatized and subsequently analyzed by gas-liquid chromatography. The methods used to analyze for alkyl phosphonates were subject to several shortcomings and modifications of the original procedure were necessary. …

Effects Of Organic Compounds On Amphibian Reproduction, Wesley J. Birge, Jeffrey A. Black, Robert A. Kuehne

KWRRI Research Reports

Aquatic toxicity tests were conducted with atrazine, carbon tetrachloride, chloroform, methylene chloride, trisodium nitrilotriacetic acid (NTA), and phenol. Each compound was administered to developmental stages of three to five amphibian species. Exposure was initiated at fertilization and maintained through 4 days posthatching. Test responses included lethality and teratogenesis. Different amphibian species exhibited varying degrees of tolerance to the selected compounds. Greatest tolerance usually was observed for the more broadly adapted semi-aquatic and terrestrial species (e.g., Bufo americanus, Bufo fowleri). The more sensitive amphibians usually included those species which normally are restricted to aquatic or moist habitats (e.g., Rana …