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Molecular, Genetic, and Biochemical Nutrition Commons™
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Articles 31 - 37 of 37
Full-Text Articles in Molecular, Genetic, and Biochemical Nutrition
Type Ii Taste Cells Participate In Mucosal Immune Surveillance, Yumei Qin, Salin Raj Palayyan, Xin Zheng, Shiyi Tian, Robert F. Margolskee, Sunil Kumar Sukumaran
Type Ii Taste Cells Participate In Mucosal Immune Surveillance, Yumei Qin, Salin Raj Palayyan, Xin Zheng, Shiyi Tian, Robert F. Margolskee, Sunil Kumar Sukumaran
Department of Nutrition and Health Sciences: Faculty Publications
The oral microbiome is second only to its intestinal counterpart in diversity and abundance but its effects on taste cells remains largely unexplored. Using single-cell RNASeq, we found that mouse taste cells, in particular, sweet and umami receptor cells that express taste 1 receptor member 3 (Tas1r3), have a gene expression signature reminiscent of Microfold (M) cells, a central player in immune surveillance in the mucosa-associated lymphoid tissue (MALT) such as those in the Peyer’s patch and tonsils. Administration of tumor necrosis factor ligand superfamily member 11 (TNFSF11; also known as RANKL), a growth factor required for differentiation …
Something Smells Fishy: How Lipid Mediators Impact The Maternal–Fetal Interface And Neonatal Development, Maranda Thompson, Arzu Ulu, Maheswari Mukherjee, Ana G. Yuil-Valdes, Melissa Thoene, Matthew Van Ormer, Rebecca Slotkowski, Teri Mauch, Ann Anderson-Berry, Corrine K. Hanson, Tara M. Nordgren, Sathish Kumar Natarajan
Something Smells Fishy: How Lipid Mediators Impact The Maternal–Fetal Interface And Neonatal Development, Maranda Thompson, Arzu Ulu, Maheswari Mukherjee, Ana G. Yuil-Valdes, Melissa Thoene, Matthew Van Ormer, Rebecca Slotkowski, Teri Mauch, Ann Anderson-Berry, Corrine K. Hanson, Tara M. Nordgren, Sathish Kumar Natarajan
Department of Nutrition and Health Sciences: Faculty Publications
Normal pregnancy relies on inflammation for implantation, placentation, and parturition, but uncontrolled inflammation can lead to poor maternal and infant outcomes. Maternal diet is one modifiable factor that can impact inflammation. Omega-3 and -6 fatty acids obtained through the diet are metabolized into bioactive compounds that effect inflammation. Recent evidence has shown that the downstream products of omega-3 and -6 fatty acids may influence physiology during pregnancy. In this review, the current knowledge relating to omega-3 and omega-6 metabolites during pregnancy will be summarized.
Something Smells Fishy: How Lipid Mediators Impact The Maternal–Fetal Interface And Neonatal Development, Maranda Thompson, Arzu Ulu, Maheswari Mukherjee, Ana G. Yuil-Valdes, Melissa K. Thoene, Matthew Van Ormer, Rebecca Slotkowski, Teri Mauch, Ann Anderson-Berry, Corrine K. Hanson, Tara M. Nordgren, Sathish Kumar Natarajan
Something Smells Fishy: How Lipid Mediators Impact The Maternal–Fetal Interface And Neonatal Development, Maranda Thompson, Arzu Ulu, Maheswari Mukherjee, Ana G. Yuil-Valdes, Melissa K. Thoene, Matthew Van Ormer, Rebecca Slotkowski, Teri Mauch, Ann Anderson-Berry, Corrine K. Hanson, Tara M. Nordgren, Sathish Kumar Natarajan
Department of Nutrition and Health Sciences: Faculty Publications
Normal pregnancy relies on inflammation for implantation, placentation, and parturition, but uncontrolled inflammation can lead to poor maternal and infant outcomes. Maternal diet is one modifiable factor that can impact inflammation. Omega-3 and -6 fatty acids obtained through the diet are metabolized into bioactive compounds that effect inflammation. Recent evidence has shown that the downstream products of omega-3 and -6 fatty acids may influence physiology during pregnancy. In this review, the current knowledge relating to omega-3 and omega-6 metabolites during pregnancy will be summarized.
Scavenger Receptor B1 Facilitates The Endocytosis Of Escherichia Coli Via Tlr4 Signaling In Mammary Gland Infection, Qamar Taban, Syed Mudasir Ahmad, Peerzada Tajamul Mumtaz, Basharat Bhat, Ehtishamul Haq, Suhail Magray, Sahar Saleem, Nadeem Shabir, Amatul Muhee, Zahid Amin Kashoo, Mahrukh Hameed Zargar6, Abrar A. Malik, Nazir A. Ganai, Riaz A. Shah
Scavenger Receptor B1 Facilitates The Endocytosis Of Escherichia Coli Via Tlr4 Signaling In Mammary Gland Infection, Qamar Taban, Syed Mudasir Ahmad, Peerzada Tajamul Mumtaz, Basharat Bhat, Ehtishamul Haq, Suhail Magray, Sahar Saleem, Nadeem Shabir, Amatul Muhee, Zahid Amin Kashoo, Mahrukh Hameed Zargar6, Abrar A. Malik, Nazir A. Ganai, Riaz A. Shah
Department of Nutrition and Health Sciences: Faculty Publications
SCARB1 belongs to class B of Scavenger receptors (SRs) that are known to be involved in binding and endocytosis of various pathogens. SRs have emerging role in regulating innate immunity and host–pathogen interactions by acting in co-ordination with Toll-like receptors.Query Little is known about the function of SCARB1 in milk-derived mammary epithelial cells (MECs). This study reports the role of SCARB1 in infection and its potential association in TLR4 signaling on bacterial challenge in Goat mammary epithelial cells (GMECs). The novelty in the establishment of MEC culture lies in the method that aims to enhance the viability of the cells …
Site-Specific Incidence Rate Of Blastocystis Hominis And Its Association With Childhood Malnutrition: Findings From A Multi-Country Birth Cohort Study, Barbie Zaman Wahid, Ahshanul Haque, Amran Gazi, Shah Mohammad Fahim, Abu Syed Golam Faruque, Mustafa Mahfuz, Tahmeed Ahmed
Site-Specific Incidence Rate Of Blastocystis Hominis And Its Association With Childhood Malnutrition: Findings From A Multi-Country Birth Cohort Study, Barbie Zaman Wahid, Ahshanul Haque, Amran Gazi, Shah Mohammad Fahim, Abu Syed Golam Faruque, Mustafa Mahfuz, Tahmeed Ahmed
Department of Nutrition and Health Sciences: Faculty Publications
In this study, we investigated the potential association between the burden of asymptomatic Blastocystis spp. (Blastocystis hominis) infection and nutritional status among children under 2 years of age using the data collected from 1,715 children from eight distinct geographic locations, including Bangladesh, Brazil, India, Peru, Tanzania, Pakistan, Nepal, and South Africa. Childhood stunting, wasting, and underweight were the outcome variables, and B. hominis infection was the exposure variable of this present study. The presence of B. hominis in nondiarrheal stools was evaluated by TaqMan Array Cards. Site-specific incidence rates were estimated using Poisson regression, and multiple generalized estimating …
The Paradox Of Child Poverty And Welfare, Tirna Purkait
The Paradox Of Child Poverty And Welfare, Tirna Purkait
Department of Nutrition and Health Sciences: Faculty Publications
The United States confronts persistent child welfare issues rooted in poverty. The age-old debate vacillates between advocating personal responsibility and bolstering social safety nets. Current welfare programs, aiming to mitigate child poverty, often fall short given the deep nexus of poverty and child maltreatment. This paper probes the intricate ties between child poverty and welfare, emphasizing state legislative variances, inherent system paradoxes, and potential policy enhancements. Exploring historical contexts, existing societal frameworks, and future reforms, this research emphasizes the urgency for all-encompassing solutions. These should tackle poverty’s core while fortifying child welfare, safeguarding the well-being of forthcoming American generations.
Site-Specific Analysis Of The Incidence Rate Of Enterotoxigenic Escherichia Coli Infection Elucidates An Association With Childhood Stunting, Wasting, And Being Underweight: A Secondary Analysis Of The Mal-Ed Birth Cohort, Ahshanul Haque, Sabiha Nasrin, Parag Palit, Rina Das, Barbie Zaman Wahid, Amran Gazi, Mustafa Mahfuz, Abu Syed Golam Faruque, Tahmeed Ahmed
Site-Specific Analysis Of The Incidence Rate Of Enterotoxigenic Escherichia Coli Infection Elucidates An Association With Childhood Stunting, Wasting, And Being Underweight: A Secondary Analysis Of The Mal-Ed Birth Cohort, Ahshanul Haque, Sabiha Nasrin, Parag Palit, Rina Das, Barbie Zaman Wahid, Amran Gazi, Mustafa Mahfuz, Abu Syed Golam Faruque, Tahmeed Ahmed
Department of Nutrition and Health Sciences: Faculty Publications
Asymptomatic infection by fecal enteropathogens is a major contributor to childhood malnutrition. Here, we investigated the incidence rate of asymptomatic infection by enterotoxigenic Escherichia coli (ETEC) and assessed its association with childhood stunting, wasting, and being underweight among children under 2 years of age. The Malnutrition and Enteric Disease birth cohort study included 1,715 children who were followed from birth to 24 months of age from eight distinct geographic locations including Bangladesh, Brazil, India, Peru, Tanzania, Pakistan, Nepal, and South Africa. The TaqMan array card assay was used to determine the presence of ETEC in the nondiarrheal stool samples collected …