Human and Clinical Nutrition Commons^™

Prediction Of Human Dietary Δ15N Intake From Standardized Food Records: Validity And Precision Of Single Meal And 24-H Diet Data, Frank Hülsemann, Karsten Koehler, Jürgen Wittsiepe, Michael Wilhelm, Annett Hilbig, Mathilde Kersting, Hans Braun, Ulrich Flenker, Wilhelm Schänzer

Department of Nutrition and Health Sciences: Faculty Publications

Natural stable isotope ratios (δ15N) of humans can be used for nutritional analyses and dietary reconstruction of modern and historic individuals and populations. Information about an individual’s metabolic state can be obtained by comparison of tissue and dietary δ¹⁵N. Different methods have been used to estimate dietary δ¹⁵N in the past; however, the validity of such predictions has not been compared to experimental values. For a total of 56 meals and 21 samples of 24-h diets, predicted and experimental δ¹⁵N values were compared. The δ¹⁵N values were predicted from self-recorded food intake …

Time Course Of Changes In Neuromuscular Responses At 30% Versus 70% 1 Repetition Maximum During Dynamic Constant External Resistance Leg Extensions To Failure, Cory M. Smith, Terry J. Housh, Ethan C. Hill, Richard J. Schmidt, Glen O. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

The purpose of the current study was to examine the time course of changes in neuromuscular responses from the vastus medialis (VM) during low versus high intensity dynamic constant external resistance (DCER) leg extension muscle actions to failure. Thirteen men performed DCER leg extensions to failure at 30% and 70% 1-repetition maximum (1-RM) as well as 1-RM measurements pretest and posttest. Electromyogaphy and mechanomyographic signals were measured from the VM. There were no differences in neuromuscular responses pretest versus posttest 1-RM. There were timedependent differences between the 30% and 70% 1-RM protocols. The initial phase of the 30% 1- RM …

Nonprofit Pay In A Competitive Market: Wage Penalty Or Premium?, Christian King, Gregory B. Lewis

Department of Nutrition and Health Sciences: Faculty Publications

Two competing theories argue that the nonprofit sector pays differently: Nonprofit employees may accept lower pay to be able to do meaningful work for a good cause, or they may earn higher pay due to nonprofit organizations’ tax exemptions and weaker incentives to hold down wages. To test these opposing expectations, we use the 2005-2013 American Community Surveys to examine pay differences among registered nurses working for nonprofit, for-profit, and public hospitals. We also test hypotheses that public and nonprofit hospitals have smaller pay disparities by gender, race, and relationship status. We find that pay is highest in nonprofit hospitals, …

Role Of Oxygen Free Radicals, Nitric Oxide And Mitochondria In Mediating Cardiac Alterations During Liver Cirrhosis Induced By Thioacetamide, G. Jayakumar Amirtharaj, Sathish Kumar Natarajan, Anna Pulimood, K. A. Balasubramanian, Aparna Venkatraman, Anup Ramachandran

Department of Nutrition and Health Sciences: Faculty Publications

Thioacetamide (TAA) administration is widely used for induction of liver cirrhosis in rats, where reactive oxygen radicals (ROS) and nitric oxide (NO) participate in development of liver damage. Cardiac dysfunction is an important complication of liver cirrhosis, but the role of ROS or NO in cardiac abnormalities during liver cirrhosis is not well understood. This was investigated in animals after TAA-induced liver cirrhosis and temporal changes in oxidative stress, NO and mitochondrial function in the heart evaluated. TAA induced elevation in cardiac levels of nitrate before development of frank liver cirrhosis, without gross histological alterations. This was accompanied by an …

Healthy Eating: How Do We Define It And Measure It? What’S The Evidence?, Christy C. Tangney, Beth A. Staffileno, Heather Rasmussen

Department of Nutrition and Health Sciences: Faculty Publications

A healthy diet can be defined in many ways, including defining one’s food intake by a dietary pattern. As described in the Dietary Guidelines for Americans Committee report, there are several defined dietary patterns associated with lower rates of chronic diseases. These include the Healthy Eating Index, Dietary Approach to Stop Hypertension, and those based on the Mediterranean diet. This review will focus on guiding health care professionals, including nurse practitioners, how a healthy diet pattern is defined, how it is measured, and a summary of recent evidence supporting the healthfulness of these dietary patterns.

Hepatocyte Abca1 Deletion Impairs Liver Insulin Signaling And Lipogenesis, Chia-Chi C. Key, Mingxia Liu, C. Lisa Kurtz, Soonkyu Chung, Elena Boudyguina, Timothy A. Dinh, Alexander Bashore, Peter E. Phelan, Barry I. Freedman, Timothy F. Osborne, Xuewei Zhu, Lijun Ma, Praveen Sethupathy, Sudha B. Biddinger, John S. Parks

Department of Nutrition and Health Sciences: Faculty Publications

Plasma membrane (PM) free cholesterol (FC) is emerging as an important modulator of signal transduction. Here, we show that hepatocyte-specific knockout (HSKO) of the cellular FC exporter, ATPbinding cassette transporter A1 (ABCA1), leads to decreased PM FC content and defective trafficking of lysosomal FC to the PM. Compared with controls, chow-fed HSKO mice had reduced hepatic (1) insulin- stimulated Akt phosphorylation, (2) activation of the lipogenic transcription factor Sterol Regulatory Element Binding Protein (SREBP)-1c, and (3) lipogenic gene expression. Consequently, Westerntype diet-fed HSKO mice were protected from steatosis. Surprisingly, HSKO mice had intact glucose metabolism; they showed normal gluconeogenic gene …

Greater Neural Adaptations Following High- Vs. Low-Load Resistance Training, Nathaniel D. M. Jenkins, Amelia A. Miramonti, Ethan C. Hill, Cory M. Smith, Kristen C. Cochrane-Snyman, Terry J. Housh, Joel T. Cramer

Department of Nutrition and Health Sciences: Faculty Publications

We examined the neuromuscular adaptations following 3 and 6 weeks of 80 vs. 30%one repetition maximum (1RM) resistance training to failure in the leg extensors. Twenty-six men (age = 23.1 ± 4.7 years) were randomly assigned to a high- (80% 1RM; n = 13) or low-load (30% 1RM; n = 13) resistance training group and completed leg extension resistance training to failure 3 times per week for 6 weeks. Testing was completed at baseline, 3, and 6 weeks of training. During each testing session, ultrasound muscle thickness and echo intensity, 1RM strength, maximal voluntary isometric contraction (MVIC) strength, and contractile …

Cardiorespiratory Fitness Is Associated With Better Executive Function In Young Women, Samuel P. Scott, Mary Jane De Souza, Karsten Koehler, Dylan L. Petkus, Laura E. Murray-Kolb

Department of Nutrition and Health Sciences: Faculty Publications

Purpose: A positive association between cardiorespiratory fitness (CRF) and cognitive function has been demonstrated mainly in children and older adults. Women attending college live in a cognitively demanding setting where optimal cognition matters but often experience declines in CRF. Our aim was to test whether CRF is associated with executive function in young adult women.

Methods: Participants in this cross-sectional study included 120 healthy women age 18–35 yr in a university setting. Each woman completed a maximal treadmill-based exercise test to determine peak oxygen uptake (V˙O_2peak), computerized tests of executive function, and questionnaires to assess motivation …

Eicosapentaenoic Acid Potentiates Brown Thermogenesis Through Ffar4-Dependent Up-Regulation Of Mir-30b And Mir-378*, Jiyoung Kim, Meshail Okla, Anjeza Erickson, Timothy P. Carr, Sathish Kumar Natarajan, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

Emerging evidence suggests that n-3 polyunsaturated fatty acids (PUFA) promote brown adipose tissue thermogenesis. However, the underlying mechanisms remain elusive. Here, we hypothesize that n-3 PUFA promotes brown adipogenesis by modulating miRNAs. To test this hypothesis, murine brown preadipocytes were induced to differentiate the fatty acids of palmitic, oleate, or eicosapentaenoic acid (EPA). The increases of brown-specific signature genes and oxygen consumption rate by EPA were concurrent with up-regulation of miR-30b and 378 but not by oleate or palmitic acid. Next, we hypothesize that free fatty acid receptor 4 (Ffar4), a functional receptor for n-3 PUFA, modulates …

Current And Past Menstrual Status Is An Important Determinant Of Femoral Neck Geometry In Exercising Women, Rebecca J. Mallinson, Nancy I. Williams, Jenna C. Gibbs, Karsten Koehler, Heather C.M. Allaway, Emily Southmayd, M. J. De Souza

Department of Nutrition and Health Sciences: Faculty Publications

Menstrual status, both past and current, has been established as an important determinant of bone mineral density (BMD) in young exercising women. However, little is known regarding the association between the cumulative effect of menstrual status and indices of bone health beyond BMD, such as bone geometry and estimated bone strength.

Purpose: This study explores the association between cumulative menstrual status and indices of bone health assessed using dualenergy x-ray absorptiometry (DXA), including femoral neck geometry and strength and areal BMD (aBMD), in exercising women.

Methods: 101 exercising women (22.0 ± 0.4 years, BMI 21.0 ± 0.2 kg/m2, 520±40 min/week …

Akt-Mtorc1 Signaling Regulates Acly To Integrate Metabolic Input To Control Of Macrophage Activation, Anthony J. Covarrubias, Halil Ibrahim Aksoylar, Jiujiu Yu, Nathaniel W. Snyder, Andrew J. Worth, Shankar S. Iyer, Jiawei Wang, Issam Ben-Sahra, Vanessa Byles, Tiffany Polynne-Stapornkul, Erika C. Espinosa, Dudley Lamming, Brendan D. Manning, Yijing Zhang, Ian A. Blair, Tiffany Horng

Department of Nutrition and Health Sciences: Faculty Publications

Macrophage activation/polarization to distinct functional states is critically supported by metabolic shifts. How polarizing signals coordinate metabolic and functional reprogramming, and the potential implications for control of macrophage activation, remains poorly understood. Here we show that IL-4 signaling co-opts the Akt-mTORC1 pathway to regulate Acly, a key enzyme in Ac-CoA synthesis, leading to increased histone acetylation and M2 gene induction. Only a subset of M2 genes is controlled in this way, including those regulating cellular proliferation and chemokine production. Moreover, metabolic signals impinge on the Akt-mTORC1 axis for such control of M2 activation. We propose that Akt-mTORC1 signaling calibrates metabolic …

Disparities In Access To Preventive Health Care Services Among Insured Children In A Cross Sectional Study, Christian King

Department of Nutrition and Health Sciences: Faculty Publications

Children with insurance have better access to care and health outcomes if their parents also have insurance. However, little is known about whether the type of parental insurance matters. This study attempts to determine whether the type of parental insurance affects the access to health care services of children. I used data from the 2009–2013 Medical Expenditure Panel Survey and estimated multivariate logistic regressions (N=26,152). I estimated how family insurance coverage affects the probability that children have a usual source of care, well-child visits in the past year, unmet medical and prescription needs, less than 1 dental visit per year, …

Four Weeks Of High- Versus Low-Load Resistance Training To Failure On The Rate Of Torque Development, Electromechanical Delay, And Contractile Twitch Properties, N.D.M. Jenkins, Terry J. Housh, S.L. Buckner, H.C. Bergstrom, C. M. Smith, Kristen C. Cochrane, E.C. Hill, Amelia A. Miramonti, Richard J. Schmidt, G. O. Johnson, Joel T. Cramer

Department of Nutrition and Health Sciences: Faculty Publications

The purpose of this study was to investigate the effects of 4-weeks of high- versus low-load resistance training to failure on rate of torque development (RTD), electromechanical delay (EMD), and contractile twitch characteristics. Fifteen men (mean±SD; age=21.7±2.4 yrs) were randomly assigned to either a high- (80% 1RM; n=7) or low-load (30% 1RM; n=8) training group and completed elbow flexion resistance training to failure 3 times per week for 4 weeks. The participants were tested at baseline, 2-, and 4-weeks of training. Peak RTD (pRTDV) and RTD at 0-30 (RTD30V), 0-50 (RTD50V), 0-100 (RTD100V), and 0-200 (RTD200V) ms, integrated EMG amplitude …

Food Insecurity And Housing Instability In Vulnerable Families, Christian King

Department of Nutrition and Health Sciences: Faculty Publications

Reducing the prevalence of household food insecurity has been a long-standing objective of the federal government. Previous research has found many negative consequences of food insecurity for families and households but has not examined its relationship with housing instability. Using longitudinal data from the Fragile Families and Child Wellbeing Study, difference-in-difference models show that food insecurity is associated with housing instability. The association remains statistically significant after accounting for potential selection and unobserved heterogeneity using propensity score matching and excluding households that experienced prior housing instability from the sample. Examining potential mediating factors, I find that material hardship explains about …

Soft Drinks Consumption And Child Behaviour Problems: The Role Of Food Insecurity And Sleep Patterns, Christian King

Department of Nutrition and Health Sciences: Faculty Publications

Objective: To examine whether the association between soft drinks consumption and child behaviour problems differs by food security status and sleep patterns in young children.

Design: Cross-sectional observational data from the Fragile Families and Child Wellbeing Study (FFCWS), which collected information on food insecurity, soft drinks consumption, sleep patterns and child behaviour problems. Bivariate and multivariate ordinary least-squares regression analyses predicting child behaviour problems and accounting for socio-economic factors and household characteristics were performed.

Setting: Twenty urban cities in the USA with a population of 200 000 or more.

Subjects: Parental interviews of 2829 children who were about 5 years …

Nutrigenomic Functions Of Ppars In Obesogenic Environments, Soonkyu Chung, Young Jun Kim, Soo Jin Yang, Yunkyoung Lee, Myoungsook Lee

Department of Nutrition and Health Sciences: Faculty Publications

Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors that mediate the effects of several nutrients or drugs through transcriptional regulation of their target genes in obesogenic environments.This review consists of three parts. First, we summarize current knowledge regarding the role of PPARs in governing the development of white and brown/beige adipocytes from uncommitted progenitor cells. Next, we discuss the interactions of dietary bioactive molecules, such as fatty acids and phytochemicals, with PPARs for the modulation of PPAR-dependent transcriptional activities and metabolic consequences. Lastly, the effects of PPAR polymorphism on obesity and metabolic outcomes are discussed. In this review, we aim …

Glucagon Regulates Hepatic Lipid Metabolism Via Camp And Insig-2 Signaling: Implication For The Pathogenesis Of Hypertriglyceridemia And Hepatic Steatosis, Hai Wang, Miaoyun Zhao, Neetu Sud, Patricia Christian, Jing Shen, Yongyan Song, Anjeza Pashaj, Kezhong Zhang, Timothy P. Carr, Qiaozhu Su

Department of Nutrition and Health Sciences: Faculty Publications

Insulin induced gene-2 (Insig-2) is an ER-resident protein that inhibits the activation of sterol regulatory element-binding proteins (SREBPs). However, cellular factors that regulate Insig-2 expression have not yet been identified. Here we reported that cyclic AMP-responsive element-binding protein H (CREBH) positively regulates mRNA and protein expression of a liver specific isoform of Insig-2, Insig-2a, which in turn hinders SREBP-1c activation and inhibits hepatic de novo lipogenesis. CREBH binds to the evolutionally conserved CRE-BP binding elements located in the enhancer region of Insig-2a and upregulates its mRNA and protein expression. Metabolic hormone glucagon and nutritional fasting activated CREBH, which upregulated expression …

Effect Of Sex On Torque, Recovery, Emg, And Mmg Responses To Fatigue, E.C. Hill, Terry J. Housh, C. M. Smith, Kristen C. Cochrane, N.D.M. Jenkins, Joel T. Cramer, Richard J. Schmidt, G. O. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

The purpose of the present investigation was to examine the effect of sex on maximal voluntary isometric contraction (MVIC) torque and the EMG and MMG responses as a result of fatiguing, intermittent, submaximal (65% of MVIC), isometric elbow flexion muscle contractions. Methods: Eighteen men and women performed MVIC trials before (pretest), after (posttest), and 5-min after (5-min recovery) performing 50 intermittent, submaximal isometric muscle contractions. Surface electromyographic (EMG) and mechanomyographic (MMG) signals were simultaneously recorded from the biceps brachii muscle. Results: As a result of the fatiguing workbout torque decreased similarly from pretest to posttest for both the men (24.0%) …

Combined Iron Deficiency And Low Aerobic Fitness Doubly Burden Academic Performance Among Women Attending University, Samuel P. Scott, Mary Jane Desouza, Karsten Koehler, Laura E. Murray-Kolb

Department of Nutrition and Health Sciences: Faculty Publications

Background: Academic success is a key determinant of future prospects for students. Cognitive functioning has been related to nutritional and physical factors. Here, we focus on iron status and aerobic fitness in young-adult female students given the high rate of iron deficiency and declines in fitness reported in this population. Objectives: We sought to explore the combined effects of iron status and fitness on academic success and to determine whether these associations are mediated by cognitive performance.

Methods: Women (n = 105) aged 18–35 y were recruited for this cross-sectional study. Data were obtained for iron biomarkers, peak oxygen …

A Qualitative Phenomenological Exploration Of Teachers’ Experience With Nutrition Education, Elisha M. Hall, Weiwen Chai, Julie A. Albrecht

Department of Nutrition and Health Sciences: Faculty Publications

Background:

Nutrition education delivered by classroom teachers has become a popular intervention designed to combat childhood obesity. However, few qualitative studies have explored nutrition education with teachers.

Purpose:

The purpose of this study was to explore how elementary teachers describe their experience with nutrition education.

Methods:

A qualitative phenomenological approach was used. Semistructured interviews, observations, and document analysis were conducted with 10 teachers who delivered nutrition education in their classrooms. Inductive coding was used to determine invariant constituents, reduce constituents to categories, and cluster categories into themes. Reliability and validity were accomplished through intercoder agreement, audio recording, triangulation, bracketing, and …

Cranberries And Cancer: An Update Of Preclinical Studies Evaluating The Cancer Inhibitory Potential Of Cranberry And Cranberry Derived Constituents, Katherine M. Weh, Jennifer L. Clarke, Laura A. Kresty

Department of Nutrition and Health Sciences: Faculty Publications

Cranberries are rich in bioactive constituents reported to influence a variety of health benefits, ranging from improved immune function and decreased infections to reduced cardiovascular disease and more recently cancer inhibition. A review of cranberry research targeting cancer revealed positive effects of cranberries or cranberry derived constituents against 17 different cancers utilizing a variety of in vitro techniques, whereas in vivo studies supported the inhibitory action of cranberries toward cancers of the esophagus, stomach, colon, bladder, prostate, glioblastoma and lymphoma. Mechanisms of cranberry-linked cancer inhibition include cellular death induction via apoptosis, necrosis and autophagy; reduction of cellular proliferation; alterations in …

Regulation Of Obesity And Metabolic Complications By Gamma And Delta Tocotrienols, Lu Zhao, Xiefan Fang, Maurice R. Marshall, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

Tocotrienols (T3s) are a subclass of unsaturated vitamin E that have been extensively studied for their anti-proliferative, anti-oxidative and anti-inflammatory properties in numerous cancer studies. Recently, T3s have received increasing attention due to their previously unrecognized property to attenuate obesity and its associated metabolic complications. In this review, we comprehensively evaluated the recent published scientific literature about the influence of T3s on obesity, with a particular emphasis on the signaling pathways involved. T3s have been demonstrated in animal models or human subjects to reduce fat mass, body weight, plasma concentrations of free fatty acid, triglycerides and cholesterol, as well as …

Successfully Changing The Landscape Of Information Distribution: Extension Food Website Reaches People Locally And Globally, Alice Henneman, Lisa Franzen-Castle, Kayla Colgrove, Vishal Singh

Department of Nutrition and Health Sciences: Faculty Publications

The goal of the Food website was to develop Internet-based content that was relevant and reached the general public and multiplier groups, such as educators, health professionals, and media outlets. The purpose of this paper was to examine whether a multi-modal approach to information delivery through increases in and changes to content, electronic mailing list creation, and social media posting impacted user access, traffic channels, and referrals from 2010 to 2014. When comparing 2010-2011 versus 2013-2014, there was a 150% increase in total pageviews, 197% increase in unique pageviews, and a 39% increase in average time spent on a page. …

Low Energy Availability In Exercising Men Is Associated With Reduced Leptin And Insulin But Not With Changes In Other Metabolic Hormones, Karsten Koehler, Neele R. Hoerner, Jenna C. Gibbs, Christoph Zinner, Hans Braun, Mary Jane De Souza, Wilhelm Schaenzer

Department of Nutrition and Health Sciences: Faculty Publications

Low energy availability, defined as low caloric intake relative to exercise energy expenditure, has been linked to endocrine alterations frequently observed in chronically energy-deficient exercising women. Our goal was to determine the endocrine effects of low energy availability in exercising men. Six exercising men (V_O2peak : 49.3 ± 2.4 ml · kg⁻¹ · min⁻¹) underwent two conditions of low energy availability (15 kcal · kg⁻¹ fat-free mass [FFM] · day⁻¹) and two energy-balanced conditions (40 kcal · kg⁻¹ FFM · day⁻¹) in randomized order. During one low energy availability and …

Relationship Between Concentrations Of Lutein And Stard3 Among Pediatric And Geriatric Human Brain Tissue, Jirayu Tanprasertsuk, Binxing Li, Paul S. Bernstein, Rohini Vishwanathan, Mary Ann Johnson, Leonard Poon, Elizabeth J. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Lutein, a dietary carotenoid, selectively accumulates in human retina and brain. While many epidemiological studies show evidence of a relationship between lutein status and cognitive health, lutein’s selective uptake in human brain tissue and its potential function in early neural development and cognitive health have been poorly evaluated at a molecular level. The objective of this study was to evaluate the cross-sectional relationship between concentrations of brain lutein and StARD3 (identified as its binding protein in retinal tissue) among three age groups: infants (1–4 months, n = 10), older adults (55–86 years, n = 8), and centenarians (98–105 years, n …

The Apoa5 Rs662799 Polymorphism Is Associated With Dyslipidemia And The Severity Of Coronary Heart Disease In Chinese Women, Yanmei Wang, Zhan Lu, Jingxiao Zhang, Yang Yang, Jing Shen, Xiaoming Zhang, Yongyan Song

Department of Nutrition and Health Sciences: Faculty Publications

Background: The APOA5 rs662799 polymorphism has been widely reported regarding its associations with the plasma lipid levels and the occurrence of coronary heart disease (CHD), whereas its relationship with the severity of CHD has not yet been explored.

Methods: Four hundred and seventy-eight angiografically defined subjects (325 CHD patients and 153 CHD-free controls) were enrolled in this study. The rs662799 polymorphism was genotyped, and the fasting lipid data were collected for all participants. The severity of CHD was evaluated for the CHD patients by using Gensini scores.

Results: The variant C allele of the rs662799 polymorphism was associated with lower …

Effects Of Fatiguing Constant Versus Alternating Intensity Intermittent Isometric Muscle Actions On Maximal Torque And Neuromuscular Responses, C. M. Smith, Terry J. Housh, E.C. Hill, Kristen C. Cochrane, N.D.M. Jenkins, Richard J. Schmidt, G. O. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Objective: To determine the effects of constant versus alternating applications of torque during fatiguing, intermittent isometric muscle actions of the leg extensors on maximal voluntary isometric contraction (MVIC) torque and neuromuscular responses. Methods: Sixteen subjects performed two protocols, each consisting of 50 intermittent isometric muscle actions of the leg extensors with equal average load at a constant 60% MVIC or alternating 40 then 80% (40/80%) MVIC with a work-to-rest ratio of 6-s on and 2-s off. MVIC torque as well as electromyographic signals from the vastus lateralis (VL), vastus medialis (VM), and rectus femoris (RF) and mechanomyographic signals from the …

Carbohydrate Intake In Form Of Gel Is Associated With Increased Gastrointestinal Distress But Not With Performance Differences Compared With Liquid Carbohydrate Ingestion During Simulated Long-Distance Triathlon, Mahdi Sareban, David Zügel, Karsten Koehler, Paul Hartveg, Martina Zügel, Uwe Schumann, Jürgen Michael Steinacker, Gunnar Treff

Department of Nutrition and Health Sciences: Faculty Publications

The ingestion of exogenous carbohydrates (CHO) during prolonged endurance exercise, such as long-distance triathlon, is considered beneficial with regard to performance. However, little is known about whether this performance benefit differs among different forms of CHO administration. To this end, the purpose of our study was to determine the impact of CHO ingestion from a semisolid source (GEL) on measures of performance and gastrointestinal (GI) comfort compared with CHO ingestion from a liquid source (LIQ). Nine well-trained triathletes participated in this randomized crossover study. Each participant completed a 60-min swim, 180-min bike exercise, and a 60-min all-out run in a …

Low Resting Metabolic Rate In Exercise-Associated Amenorrhea Is Not Due To A Reduced Proportion Of Highly Active Metabolic Tissue Compartments, Karsten Koehler, Nancy I. Williams, Rebecca J. Mallinson, Emily A. Southmayd, Heather C.M. Allaway, Mary Jane De Souza

Department of Nutrition and Health Sciences: Faculty Publications

Exercising women with menstrual disturbances frequently display a low resting metabolic rate (RMR) when RMR is expressed relative to body size or lean mass. However, normalizing RMR for body size or lean mass does not account for potential differences in the size of tissue compartments with varying metabolic activities. To explore whether the apparent RMR suppression in women with exercise-associated amenorrhea is a consequence of a lower proportion of highly active metabolic tissue compartments or the result of metabolic adaptations related to energy conservation at the tissue level, RMR and metabolic tissue compartments were compared among exercising women with amenorrhea …

Effects Of Short-Term Dynamic Constant External Resistance Training And Subsequent Detraining On Strength Of The Trained And Untrained Limbs: A Randomized Trial, Pablo B. Costa, Trent J. Herda, Ashley A. Herda, Joel T. Cramer

Department of Nutrition and Health Sciences: Faculty Publications

Short-term resistance training has been shown to increase isokinetic muscle strength and performance after only two to nine days of training. The purpose of this study was to examine the effects of three days of unilateral dynamic constant external resistance (DCER) training and detraining on the strength of the trained and untrained legs. Nineteen men were randomly assigned to a DCER training group or a non-training control group. Subjects visited the laboratory eight times, the first visit was a familiarization session, the second visit was a pre-training assessment, the subsequent three visits were for training sessions (if assigned to the …