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Articles 1 - 4 of 4
Full-Text Articles in Other Neuroscience and Neurobiology
Sexually Dimorphic Oxytocin Receptor-Expressing Neurons In The Anteroventral Periventricular Nucleus Regulates Maternal Behavior, Kaustubh Sharma
Sexually Dimorphic Oxytocin Receptor-Expressing Neurons In The Anteroventral Periventricular Nucleus Regulates Maternal Behavior, Kaustubh Sharma
LSU Doctoral Dissertations
The neurohypophysial hormone oxytocin is involved in the regulation of social behaviors, including social recognition, pair bonding, and sex-specific parental behaviors in a variety of species. Oxytocin triggers these social behaviors by binding to oxytocin receptors (OXTR) in various parts of the brain. Oxytocin-induced sex-typical behavior, therefore, suggests a sexual dimorphic distribution of OXTR in the brain. In recent years, the oxytocin system in the brain received tremendous attention as a potential pharmacological target for treatment of many psychiatric disorders, such as anxiety, autism spectrum disorders, and even sex-specific psychiatric disorder like postpartum depression (PPD). An important problem and a …
Chemosensory Communication And Neural Substrates Of Social Behavior In The African Cichlid Fish, Astatotilapia Burtoni, Karen Elizabeth Field
Chemosensory Communication And Neural Substrates Of Social Behavior In The African Cichlid Fish, Astatotilapia Burtoni, Karen Elizabeth Field
LSU Doctoral Dissertations
Social animals must constantly assess their environment to make appropriate decisions. In several fish species, chemosensory signaling is crucial for social communication, conveying information on sex, reproductive state, and social status. Despite its importance in fishes, relatively little is known about how they employ chemical signaling, with only a few of the over 30,000 extant species investigated thus far. Further, there is a scarcity of information about where and how socially-relevant chemosensory signals are processed in the brain of fishes, or how chemosensory signals are integrated with other senses to elicit appropriate behaviors. For my doctoral research, I examined the …
Regulation Of Epithelial Sodium Channels In Vasopressin Neurons In The Hypothalamus, Natalie Jean Mills
Regulation Of Epithelial Sodium Channels In Vasopressin Neurons In The Hypothalamus, Natalie Jean Mills
LSU Doctoral Dissertations
Salt-sensitive individuals have blood pressure that is unusually sensitive to salt intake. Because salt-sensitivity is a common disorder and may cause high blood pressure, it is a significant public health concern. All three epithelial Na+ channel (ENaC) subunits (a, b, and g) and the mineralocorticoid receptor (MR), a known regulator of ENaC, are expressed by vasopressin (VP) synthesizing magnocellular neurons in the hypothalamic supraoptic (SON) and paraventricular (PVN) nuclei. A growing body of evidence indicates that epithelial Na+ channels (ENaCs) in the hypothalamus play a significant role in the development of salt-sensitivity. My dissertation research tests the hypothesis …
Endocytosis And The Nitric Oxide-Dependent Release Of Chloride, Vernon K. Dunn Jr
Endocytosis And The Nitric Oxide-Dependent Release Of Chloride, Vernon K. Dunn Jr
LSU Doctoral Dissertations
Understanding the regulation of retinal synapses is a key step in elucidating the processing of information in the retina. Our lab has previously shown that nitric oxide (NO) can alter the synaptic response properties of amacrine cells by releasing Cl- from internal acidic compartments. This alteration in the Cl- gradient brings about a positive shift in the reversal potential of the GABA-gated current, which can convert inhibitory synapses into excitatory synapses. Recently, we have shown that the cystic fibrosis transmembrane regulator (CFTR) Cl- channel is involved in the Cl- release. Here, we test the hypothesis that (acidic) synaptic vesicles are …