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Molecular and Cellular Neuroscience Commons™
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Full-Text Articles in Molecular and Cellular Neuroscience
Mechanisms Of Microglia Mediated Apolipoprotien E Neurotoxicity, Pardeep Singh
Mechanisms Of Microglia Mediated Apolipoprotien E Neurotoxicity, Pardeep Singh
Dissertations and Theses
No abstract provided.
The Progression Of Aβ Proteins In The Retrosplenial Cortex Using An App/Ps1 Alzheimer’S Disease Transgenic Rodent Model, Maha H. Rashid
The Progression Of Aβ Proteins In The Retrosplenial Cortex Using An App/Ps1 Alzheimer’S Disease Transgenic Rodent Model, Maha H. Rashid
Senior Independent Study Theses
Alzheimer’s disease is the most common form of dementia in the world with a new case of dementia diagnosed every 3.2 seconds. For over 25 years the amyloid cascade hypothesis has existed as a mechanism of understanding and diagnosing Alzheimer’s Disease. The amyloid cascade hypothesis suggests that Alzheimer’s Disease is sequential in protein progression and proliferative from the medial temporal lobe to the rest of the brain. Hypometabolism of brain regions has also been correlated to plaque deposition and hypometabolism is observed in brain regions that make up the default mode network, specifically the retrosplenial cortex, which is not accounted …