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Molecular and Cellular Neuroscience Commons

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Articles 1 - 3 of 3

Full-Text Articles in Molecular and Cellular Neuroscience

Characterizing The Rogfp2-Orp1 Fluorescent Biosensor For Detecting Oxidative Stress In Mammalian Cells, Sara A. Doan, Stevie Norcross, Mathew Tantama Sep 2015

Characterizing The Rogfp2-Orp1 Fluorescent Biosensor For Detecting Oxidative Stress In Mammalian Cells, Sara A. Doan, Stevie Norcross, Mathew Tantama

The Summer Undergraduate Research Fellowship (SURF) Symposium

Parkinson’s disease is a neurodegenerative disease involving the death of neurons in the substantia nigra and loss of the neurotransmitter, dopamine. The disease leads to progressive loss of motor control. Exact causes and mechanisms by which Parkinson’s disease proceeds are unknown, however, previous experiments determine oxidative stress in mitochondria as a factor that results in cell death. Strategies have been implemented to generate fluorescent biosensors to monitor reactive oxygen species (ROS) concentrations while simultaneously measuring the spatiotemporal distribution and correlation between the ROS, cellular function and organelle. Orp1, an enzyme found in yeast, is a sensitive oxidizing species and when …


Characterizing Orphan Gpcrs In Molluscan Neurons Through Bioinformatics, Preetham Ganupuru Apr 2015

Characterizing Orphan Gpcrs In Molluscan Neurons Through Bioinformatics, Preetham Ganupuru

Georgia State Undergraduate Research Conference

No abstract provided.


Does The Crayfish Tail Fan Sense Chemicals, Semira Adella, Imon Allen, Tyler Flot Apr 2015

Does The Crayfish Tail Fan Sense Chemicals, Semira Adella, Imon Allen, Tyler Flot

Georgia State Undergraduate Research Conference

No abstract provided.