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Articles 1 - 9 of 9
Full-Text Articles in Developmental Neuroscience
Effects Of Pre-Pubertal Social Experiences On The Responsiveness Of Juvenile Rats To Predator Odors, Stephen M. Siviy
Effects Of Pre-Pubertal Social Experiences On The Responsiveness Of Juvenile Rats To Predator Odors, Stephen M. Siviy
Psychology Faculty Publications
The extent to which social variables may modulate the fear associated with a predator cue was assessed in juvenile rats. Cat odor reduced play to a comparable extent in both socially housed and isolate-housed rats, although socially housed rats exhibited more risk assessment during extinction. Rats that had played previously in the context used for assessing fear hid slightly less when exposed to cat odor than those rats that had not played previously in the testing context. However, no other differences were found between these two groups suggesting that prior social experience with the testing context has minimal effects on …
Maternal Cocaine Administration In Mice Alters Dna Methylation And Gene Expression In Hippocampal Neurons Of Neonatal And Prepubertal Offspring, Svetlana I. Novikova, Fang He, Jie Bai, Nicholas J. Cutrufello, Michael S. Lidow, Ashiwel S. Undieh
Maternal Cocaine Administration In Mice Alters Dna Methylation And Gene Expression In Hippocampal Neurons Of Neonatal And Prepubertal Offspring, Svetlana I. Novikova, Fang He, Jie Bai, Nicholas J. Cutrufello, Michael S. Lidow, Ashiwel S. Undieh
Publications and Research
Previous studies documented significant behavioral changes in the offspring of cocaine-exposed mothers. We now explore the hypothesis that maternal cocaine exposure could alter the fetal epigenetic machinery sufficiently to cause lasting neurochemical and functional changes in the offspring. Pregnant CD1 mice were administered either saline or 20 mg/kg cocaine twice daily on gestational days 8–19. Male pups from each of ten litters of the cocaine and control groups were analyzed at 3 (P3) or 30 (P30) days postnatum. Global DNA methylation, methylated DNA immunoprecipitation followed by CGI2 microarray profiling and bisulfite sequencing, as well as quantitative real-time RT-PCR gene expression …
Effects Of Neonatal Handling On Play Behavior And Fear Towards A Predator Odor In Juvenile Rats, Stephen M. Siviy
Effects Of Neonatal Handling On Play Behavior And Fear Towards A Predator Odor In Juvenile Rats, Stephen M. Siviy
Psychology Faculty Publications
The effects of brief daily separation, also known as "handling," during the first 2 weeks of life on play behavior and fearfulness toward a predatory odor were assessed in juvenile rats. Handled rats were more playful than nonhandled control rats, and while handling had no effect on the direct response of these rats toward a predatory odor, handled rats did not exhibit a conditioned suppression of play when tested later in the same context where they had been exposed to the predatory odor. Handled rats were still wary of the environment in that they continued to show a heightened level …
Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell
Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell
Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell
Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell
Selected Works Temporary Series
No abstract provided.
Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell
Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell
Departmental Papers (Psych)
No abstract provided.
Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell
Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell
Departmental Papers (Psych)
No abstract provided.
Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell
Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell
Departmental Papers (Psych)
No abstract provided.