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Full-Text Articles in Developmental Neuroscience

Mapping Molecular Datasets Back To The Brain Regions They Are Extracted From: Remembering The Native Countries Of Hypothalamic Expatriates And Refugees, Arshad Khan, Alice Grant, Anais Martinez, Gully Burns, Brendan Thatcher, Vishwanath Anekonda, Benjamin Thompson, Zachary Roberts, Daniel Moralejo, James Blevins Jun 2018

Mapping Molecular Datasets Back To The Brain Regions They Are Extracted From: Remembering The Native Countries Of Hypothalamic Expatriates And Refugees, Arshad Khan, Alice Grant, Anais Martinez, Gully Burns, Brendan Thatcher, Vishwanath Anekonda, Benjamin Thompson, Zachary Roberts, Daniel Moralejo, James Blevins

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This article, which includes novel unpublished data along with commentary and analysis,focuses on approaches to link transcriptomic, proteomic, and peptidomic datasets mined frombrain tissue to the original locations within the brain that they are derived from using digital atlasmapping techniques. We use, as an example, the transcriptomic, proteomic and peptidomicanalyses conducted in the mammalian hypothalamus. Following a brief historical overview, wehighlight studies that have mined biochemical and molecular information from the hypothalamusand then lay out a strategy for how these data can be linked spatially to the mapped locations in acanonical brain atlas where the data come from, thereby allowing …


Behavioral, Biochemical, And Molecular Indices Of Stress Are Enhanced In Female Versus Male Rats Experiencing Nicotine Withdrawal, Laura O'Dell May 2013

Behavioral, Biochemical, And Molecular Indices Of Stress Are Enhanced In Female Versus Male Rats Experiencing Nicotine Withdrawal, Laura O'Dell

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Stress is a major factor that promotes tobacco use and relapse during withdrawal. Although women are more vulnerable to tobacco use than men, the manner in which stress contributes to tobacco use in women versus men is unclear.Thus, the goal of this study was to compare behavioral and biological indices of stress in male and female rats during nicotine withdrawal. Since the effects of nicotine withdrawal are age-dependent, this study also included adolescent rats. An initial study was conducted to provide comparable nicotine doses across age and sex during nicotine exposure and withdrawal. Rats received sham surgery or an osmotic …


Effect Of Nicotine On Body Composition, Laura O'Dell May 2012

Effect Of Nicotine On Body Composition, Laura O'Dell

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No abstract provided.


Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell Jan 2011

Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell

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No abstract provided.


A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell Jan 2009

A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell

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No abstract provided.


Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell Jan 2009

Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell

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No abstract provided.


Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell Jan 2009

Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell

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No abstract provided.


Pdf Of All O'Dell Manuscripts, Laura O'Dell Jan 2009

Pdf Of All O'Dell Manuscripts, Laura O'Dell

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No abstract provided.


Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell Jan 2009

Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell

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No abstract provided.


Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell Jan 2009

Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell Jan 2009

Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell

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No abstract provided.


Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell Jan 2009

Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell Jan 2009

The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell Jan 2008

Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell

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No abstract provided.


Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell Jan 2008

Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell

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No abstract provided.


Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell Jan 2008

Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Adolescent Nicotine Exposure Produces Less Affective Measures Of Withdrawal Relative To Adult Nicotine Exposure In Male Rats, Laura O'Dell Jan 2007

Adolescent Nicotine Exposure Produces Less Affective Measures Of Withdrawal Relative To Adult Nicotine Exposure In Male Rats, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Crf–Crf1 System Activation Mediates Withdrawal-Induced Increases In Nicotine Self-Administration In Nicotine-Dependent Rats., Laura O'Dell Jan 2007

Crf–Crf1 System Activation Mediates Withdrawal-Induced Increases In Nicotine Self-Administration In Nicotine-Dependent Rats., Laura O'Dell

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No abstract provided.


Diminished Nicotine Withdrawal In Adolescent Rats: Implications For Vulnerability To Addiction, Laura O'Dell Jan 2007

Diminished Nicotine Withdrawal In Adolescent Rats: Implications For Vulnerability To Addiction, Laura O'Dell

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No abstract provided.


“Nicotine Deprivation Effect” In Rats With Intermittent 23-Hour Access To Intravenous Nicotine Self-Administration, Laura O'Dell Jan 2007

“Nicotine Deprivation Effect” In Rats With Intermittent 23-Hour Access To Intravenous Nicotine Self-Administration, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Viral Vector-Induced Amygdala Npy Overexpression Reverses Increased Alcohol Intake Caused By Repeated Deprivations In Wistar Rats, Laura O'Dell Jan 2007

Viral Vector-Induced Amygdala Npy Overexpression Reverses Increased Alcohol Intake Caused By Repeated Deprivations In Wistar Rats, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Behavioral And Neurochemical Responses To Cocaine In Periadolescent And Adult Rats, Laura O'Dell Jan 2006

Behavioral And Neurochemical Responses To Cocaine In Periadolescent And Adult Rats, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Corticotropin-Releasing Factor Within The Central Nucleus Of The Amygdala Mediates Enhanced Ethanol Self-Administration In Ethanol-Dependent Rats During Withdrawal., Laura O'Dell Jan 2006

Corticotropin-Releasing Factor Within The Central Nucleus Of The Amygdala Mediates Enhanced Ethanol Self-Administration In Ethanol-Dependent Rats During Withdrawal., Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Biphasic Alterations In Serotonin1b (5-Ht1b) Receptor Function During Abstinence From Extended Cocaine Self-Administration, Laura O'Dell Jan 2006

Biphasic Alterations In Serotonin1b (5-Ht1b) Receptor Function During Abstinence From Extended Cocaine Self-Administration, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Diminished Nicotine Withdrawal In Adolescent Rats: Implications For Vulnerability To Addiction, Laura O'Dell Jan 2006

Diminished Nicotine Withdrawal In Adolescent Rats: Implications For Vulnerability To Addiction, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Extended Access To Nicotine Self-Administration Leads To Dependence: Circadian Measures, Withdrawal Measures, And Extinction Behavior In Rats, Laura O'Dell Jan 2006

Extended Access To Nicotine Self-Administration Leads To Dependence: Circadian Measures, Withdrawal Measures, And Extinction Behavior In Rats, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Unlimited Access To Heroin Self-Administration: Independent Motivational Markers Of Opiate Dependence, Laura O'Dell Jan 2006

Unlimited Access To Heroin Self-Administration: Independent Motivational Markers Of Opiate Dependence, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Epipregnanolone And A Novel Synthetic Neuroactive Steroid Reduce Reduce Alcohol Self-Administration In Rats., Laura O'Dell Jan 2005

Epipregnanolone And A Novel Synthetic Neuroactive Steroid Reduce Reduce Alcohol Self-Administration In Rats., Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Stress Enhancement Of Craving During Sobriety: A Risk For Relapse, Laura O'Dell Jan 2005

Stress Enhancement Of Craving During Sobriety: A Risk For Relapse, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Enhanced Operant Self-Administration Of Alcohol In Wistar Rats Receiving Intermittent Versus Continuous Alcohol Vapor Exposure, Laura O'Dell Jan 2004

Enhanced Operant Self-Administration Of Alcohol In Wistar Rats Receiving Intermittent Versus Continuous Alcohol Vapor Exposure, Laura O'Dell

Selected Works Temporary Series

No abstract provided.