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Full-Text Articles in Developmental Neuroscience

Mapping Molecular Datasets Back To The Brain Regions They Are Extracted From: Remembering The Native Countries Of Hypothalamic Expatriates And Refugees, Arshad Khan, Alice Grant, Anais Martinez, Gully Burns, Brendan Thatcher, Vishwanath Anekonda, Benjamin Thompson, Zachary Roberts, Daniel Moralejo, James Blevins Jun 2018

Mapping Molecular Datasets Back To The Brain Regions They Are Extracted From: Remembering The Native Countries Of Hypothalamic Expatriates And Refugees, Arshad Khan, Alice Grant, Anais Martinez, Gully Burns, Brendan Thatcher, Vishwanath Anekonda, Benjamin Thompson, Zachary Roberts, Daniel Moralejo, James Blevins

Selected Works Temporary Series

This article, which includes novel unpublished data along with commentary and analysis,focuses on approaches to link transcriptomic, proteomic, and peptidomic datasets mined frombrain tissue to the original locations within the brain that they are derived from using digital atlasmapping techniques. We use, as an example, the transcriptomic, proteomic and peptidomicanalyses conducted in the mammalian hypothalamus. Following a brief historical overview, wehighlight studies that have mined biochemical and molecular information from the hypothalamusand then lay out a strategy for how these data can be linked spatially to the mapped locations in acanonical brain atlas where the data come from, thereby allowing …


Mapping Molecular Datasets Back To The Brain Regions They Are Extracted From: Remembering The Native Countries Of Hypothalamic Expatriates And Refugees, Khan, Alice Grant, Anais Martinez, Gully Burns, Brendan Thatcher, Vishwanath Anekonda, Benjamin Thompson, Zachary Roberts, Daniel Moralejo, James Blevins Jun 2018

Mapping Molecular Datasets Back To The Brain Regions They Are Extracted From: Remembering The Native Countries Of Hypothalamic Expatriates And Refugees, Khan, Alice Grant, Anais Martinez, Gully Burns, Brendan Thatcher, Vishwanath Anekonda, Benjamin Thompson, Zachary Roberts, Daniel Moralejo, James Blevins

Departmental Papers (Biology)

This article, which includes novel unpublished data along with commentary and analysis,focuses on approaches to link transcriptomic, proteomic, and peptidomic datasets mined frombrain tissue to the original locations within the brain that they are derived from using digital atlasmapping techniques. We use, as an example, the transcriptomic, proteomic and peptidomicanalyses conducted in the mammalian hypothalamus. Following a brief historical overview, wehighlight studies that have mined biochemical and molecular information from the hypothalamusand then lay out a strategy for how these data can be linked spatially to the mapped locations in acanonical brain atlas where the data come from, thereby allowing …


Behavioral, Biochemical, And Molecular Indices Of Stress Are Enhanced In Female Versus Male Rats Experiencing Nicotine Withdrawal, Laura O'Dell May 2013

Behavioral, Biochemical, And Molecular Indices Of Stress Are Enhanced In Female Versus Male Rats Experiencing Nicotine Withdrawal, Laura O'Dell

Selected Works Temporary Series

Stress is a major factor that promotes tobacco use and relapse during withdrawal. Although women are more vulnerable to tobacco use than men, the manner in which stress contributes to tobacco use in women versus men is unclear.Thus, the goal of this study was to compare behavioral and biological indices of stress in male and female rats during nicotine withdrawal. Since the effects of nicotine withdrawal are age-dependent, this study also included adolescent rats. An initial study was conducted to provide comparable nicotine doses across age and sex during nicotine exposure and withdrawal. Rats received sham surgery or an osmotic …


Behavioral, Biochemical, And Molecular Indices Of Stress Are Enhanced In Female Versus Male Rats Experiencing Nicotine Withdrawal, Laura O'Dell May 2013

Behavioral, Biochemical, And Molecular Indices Of Stress Are Enhanced In Female Versus Male Rats Experiencing Nicotine Withdrawal, Laura O'Dell

Departmental Papers (Psych)

Stress is a major factor that promotes tobacco use and relapse during withdrawal. Although women are more vulnerable to tobacco use than men, the manner in which stress contributes to tobacco use in women versus men is unclear.Thus, the goal of this study was to compare behavioral and biological indices of stress in male and female rats during nicotine withdrawal. Since the effects of nicotine withdrawal are age-dependent, this study also included adolescent rats. An initial study was conducted to provide comparable nicotine doses across age and sex during nicotine exposure and withdrawal. Rats received sham surgery or an osmotic …


Effect Of Nicotine On Body Composition, Laura O'Dell May 2012

Effect Of Nicotine On Body Composition, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Effect Of Nicotine On Body Composition, Laura O'Dell May 2012

Effect Of Nicotine On Body Composition, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell Jan 2011

Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell Jan 2011

Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell Jan 2009

A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell Jan 2009

Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell Jan 2009

Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Pdf Of All O'Dell Manuscripts, Laura O'Dell Jan 2009

Pdf Of All O'Dell Manuscripts, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell Jan 2009

Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell Jan 2009

Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell Jan 2009

Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell Jan 2009

Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell Jan 2009

The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell Jan 2009

The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell Jan 2009

Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell Jan 2009

Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell Jan 2009

Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell Jan 2009

A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell Jan 2009

Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell Jan 2009

Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell Jan 2009

Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell Jan 2008

Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell Jan 2008

Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell Jan 2008

Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell Jan 2008

Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell Jan 2008

Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.