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Full-Text Articles in Neuroscience and Neurobiology
Dual And Opposing Modulatory Effects Of Serotonin On Crayfish Lateral Giant Escape Command Neurons, Terri Teshiba, Ashkan Shamsian, Bahram Yashar, Shih-Rung Yeh, Donald H. Edwards, Franklin B. Krasne
Dual And Opposing Modulatory Effects Of Serotonin On Crayfish Lateral Giant Escape Command Neurons, Terri Teshiba, Ashkan Shamsian, Bahram Yashar, Shih-Rung Yeh, Donald H. Edwards, Franklin B. Krasne
Neuroscience Institute Faculty Publications
Serotonin modulates afferent synaptic transmission to the lateral giant neurons of crayfish, which are command neurons for escape behavior. Low concentrations, or high concentrations reached gradually, are facilitatory, whereas high concentrations reached rapidly are inhibitory. The modulatory effects rapidly reverse after brief periods of application, whereas longer periods of application are followed by facilitation that persists for hours. These effects of serotonin can be reproduced by models that involve multiple interacting intracellular signaling systems that are each stimulated by serotonin. The dependence of the neuromodulatory effect on dose, rate, and duration of modulator application may be relevant to understanding the …
Patterns Of Neural Circuit Activation And Behavior During Dominance Hierarchy Formation In Freely Behaving Crayfish, Jens Herberholz, Fadi A. Issa, Donald H. Edwards
Patterns Of Neural Circuit Activation And Behavior During Dominance Hierarchy Formation In Freely Behaving Crayfish, Jens Herberholz, Fadi A. Issa, Donald H. Edwards
Neuroscience Institute Faculty Publications
Creation of a dominance hierarchy within a population of animals typically involves a period of agonistic activity in which winning and losing decide relative positions in the hierarchy. Among crayfish, fighting between size-matched animals leads to an abrupt change of behavior as the new subordinate retreats and escapes from the attacks and approaches of the dominant (Issa et al., 1999). We used high-speed videography and electrical recordings of aquarium field potentials to monitor the release of aggressive and defensive behavior, including the activation of neural circuits for four different tail-flip behaviors. We found that the sequence of tail-flip circuit excitation …