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Developmental Neuroscience

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Articles 361 - 390 of 409

Full-Text Articles in Neuroscience and Neurobiology

Stress Enhancement Of Craving During Sobriety: A Risk For Relapse, Laura O'Dell Jan 2005

Stress Enhancement Of Craving During Sobriety: A Risk For Relapse, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Epipregnanolone And A Novel Synthetic Neuroactive Steroid Reduce Reduce Alcohol Self-Administration In Rats., Laura O'Dell Jan 2005

Epipregnanolone And A Novel Synthetic Neuroactive Steroid Reduce Reduce Alcohol Self-Administration In Rats., Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Sexually Dimorphic Effects Of Prenatal Stress On Cognition, Hormonal Responses, And Central Neurotransmitters, Rachel E. Bowman, Neil J. Maclusky, Yessenia Sarmiento, Maya Frankfurt, Marisa Gordon, Victoria N. Luine Aug 2004

Sexually Dimorphic Effects Of Prenatal Stress On Cognition, Hormonal Responses, And Central Neurotransmitters, Rachel E. Bowman, Neil J. Maclusky, Yessenia Sarmiento, Maya Frankfurt, Marisa Gordon, Victoria N. Luine

Psychology Faculty Publications

Exposure to stress during gestation results in physiological and behavioral alterations that persist into adulthood. This study examined the effects of prenatal stress on the postnatal expression of sexually differentiated cognitive, hormonal, and neurochemical profiles in male and female rats. Pregnant dams were subjected to restraint stress three times daily for 45 min during d 14-21 of pregnancy. The offspring of control and prenatally stressed dams were tested for anxiety-related and cognitive behaviors, stress and gonadal steroid hormone levels, as well as monoamines and metabolite levels in selected brain regions. Postnatal testosterone levels (measured at 1 and 5 d) did …


Enhanced Operant Self-Administration Of Alcohol In Wistar Rats Receiving Intermittent Versus Continuous Alcohol Vapor Exposure, Laura O'Dell Jan 2004

Enhanced Operant Self-Administration Of Alcohol In Wistar Rats Receiving Intermittent Versus Continuous Alcohol Vapor Exposure, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Ethanol-Induced Increases In Neuroactive Steroids In The Rat Brain And Plasma Are Absent In Adrenalectomized And Gonadectomized Rats, Laura O'Dell Jan 2004

Ethanol-Induced Increases In Neuroactive Steroids In The Rat Brain And Plasma Are Absent In Adrenalectomized And Gonadectomized Rats, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Nicotine Withdrawal In Adolescent And Adult Rats, Laura O'Dell Jan 2004

Nicotine Withdrawal In Adolescent And Adult Rats, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Serotonin1b Receptors In The Ventral Tegmental Area Modulate Cocaine-Induced Elevations Of Dopamine Release In The Nucleus Accumbens, Laura O'Dell Jan 2004

Serotonin1b Receptors In The Ventral Tegmental Area Modulate Cocaine-Induced Elevations Of Dopamine Release In The Nucleus Accumbens, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Neurobiological Mechanisms In The Transition From Drug Use To Drug Dependence, Laura O'Dell Jan 2004

Neurobiological Mechanisms In The Transition From Drug Use To Drug Dependence, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Ethanol-Induced Increases In Neuroactive Steroids In The Rat Brain And Plasma Are Absent In Adrenalectomized And Gonadectomized Rats, Laura O'Dell Jan 2004

Ethanol-Induced Increases In Neuroactive Steroids In The Rat Brain And Plasma Are Absent In Adrenalectomized And Gonadectomized Rats, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Nicotine Withdrawal In Adolescent And Adult Rats, Laura O'Dell Jan 2004

Nicotine Withdrawal In Adolescent And Adult Rats, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Serotonin1b Receptors In The Ventral Tegmental Area Modulate Cocaine-Induced Elevations Of Dopamine Release In The Nucleus Accumbens, Laura O'Dell Jan 2004

Serotonin1b Receptors In The Ventral Tegmental Area Modulate Cocaine-Induced Elevations Of Dopamine Release In The Nucleus Accumbens, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Loss-Of-Function Analysis Of Epha Receptors In Retinotectal Mapping, David Feldheim, Masaru Nakamoto, Miriam Osterfield, Nicholas Gale, Thomas Dechiara, Rajat Rohatgi, George Yancopoulos, John Flanagan Jan 2004

Loss-Of-Function Analysis Of Epha Receptors In Retinotectal Mapping, David Feldheim, Masaru Nakamoto, Miriam Osterfield, Nicholas Gale, Thomas Dechiara, Rajat Rohatgi, George Yancopoulos, John Flanagan

Biology Faculty Publications

EphA tyrosine kinases are thought to act as topographically specific receptors in the well-characterized projection map from the retina to the tectum. Here, we describe a loss-of-function analysis of EphA receptors in retinotectal mapping. Expressing patches of a cytoplasmically truncated EphA3 receptor in chick retina caused temporal axons to have reduced responsiveness to posterior tectal repellent activity in vitro  and to shift more posteriorly within the map in vivo . A gene disruption of mouse EphA5, replacing the intracellular domain with beta-galactosidase, reduced in vitro  responsiveness of temporal axons to posterior target membranes. It also caused map abnormalities in vivo …


Neurobiological Mechanisms In The Transition From Drug Use To Drug Dependence, Laura O'Dell Jan 2004

Neurobiological Mechanisms In The Transition From Drug Use To Drug Dependence, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Exploring Brain-Based Learning As A Basis For Developing Technology Education Curriculum, Adam G. Saltmarsh Jul 2003

Exploring Brain-Based Learning As A Basis For Developing Technology Education Curriculum, Adam G. Saltmarsh

Honors Capstones

Capstone submitted as a graduation requirement for the BSU Honors Program.


Acutely-Administered Ethanol Participates In Testosterone Synthesis And Increases Testosterone In The Rat Brain., Laura O'Dell Jan 2003

Acutely-Administered Ethanol Participates In Testosterone Synthesis And Increases Testosterone In The Rat Brain., Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Acutely-Administered Ethanol Participates In Testosterone Synthesis And Increases Testosterone In The Rat Brain., Laura O'Dell Jan 2003

Acutely-Administered Ethanol Participates In Testosterone Synthesis And Increases Testosterone In The Rat Brain., Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


D1 Dopamine Receptor Regulation Of Microtubule-Associated Protein-2 Phosphorylation In Developing Cerebral Cortical Neurons, Z.-M. Song, Ashiwel S. Undieh, Y.-Y. Fang, L. Zhang, S. Dracheva, S.C. Sealfon, M.S. Lidow Jul 2002

D1 Dopamine Receptor Regulation Of Microtubule-Associated Protein-2 Phosphorylation In Developing Cerebral Cortical Neurons, Z.-M. Song, Ashiwel S. Undieh, Y.-Y. Fang, L. Zhang, S. Dracheva, S.C. Sealfon, M.S. Lidow

Publications and Research

This study addresses the hypothesis that the previously described capacity of D1 dopamine receptors (D1Rs) to regulate dendritic growth in developing cortical neurons may involve alterations in the phosphorylation state of microtubuleassociated protein-2 (MAP2). The changes in phosphorylation of this protein are known to affect its ability to stabilize the dendritic cytoskeleton. The study involved two systems: primary cultures of mouse cortical neurons grown in the presence of the D1R agonists, SKF82958 or A77636, and the cortex of neonatal transgenic mice overexpressing the D1A subtype of D1R. In both models, a decrease in dendritic extension corresponded with an elevation in …


Enhanced Locomotor, Reinforcing, And Neurochemical Effects Of Cocaine In Serotonin 5-Hydroxytryptamine 2c Receptor Mutant Mice, Laura O'Dell Jan 2002

Enhanced Locomotor, Reinforcing, And Neurochemical Effects Of Cocaine In Serotonin 5-Hydroxytryptamine 2c Receptor Mutant Mice, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Enhanced Locomotor, Reinforcing, And Neurochemical Effects Of Cocaine In Serotonin 5-Hydroxytryptamine 2c Receptor Mutant Mice, Laura O'Dell Jan 2002

Enhanced Locomotor, Reinforcing, And Neurochemical Effects Of Cocaine In Serotonin 5-Hydroxytryptamine 2c Receptor Mutant Mice, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Domain-Specific Olivocerebellar Projection Regulated By The Epha-Ephrin-A Interaction, Kazuhiko Nishida, John Flanagan, Masaru Nakamoto Jan 2002

Domain-Specific Olivocerebellar Projection Regulated By The Epha-Ephrin-A Interaction, Kazuhiko Nishida, John Flanagan, Masaru Nakamoto

Biology Faculty Publications

Neural maps in the vertebrate central nervous system often show discontinuously segregated, domain-to-domain patterns. However, the molecular mechanism that establishes such maps is not well understood. Here we show that in the chicken olivocerebellar system, EphA receptors and ephrin-As are expressed with distinct levels and combinations in mapping domains. When ephrin-A2 is retrovirally overexpressed in the cerebellum, the olivocerebellar map is disrupted, excluding axons with high receptor activity from ectopic expression domains. Conversely, overexpression of a truncated EphA3 receptor in the cerebellum reduces endogenous ligand activity to undetectable levels and causes aberrant mapping, with high receptor axons invading high ligand …


Neuromotor And Cognitive Development In Children With Cerebral Palsy In Relation To Neural Plasticity, Vaniecea Pollard May 2001

Neuromotor And Cognitive Development In Children With Cerebral Palsy In Relation To Neural Plasticity, Vaniecea Pollard

McCabe Thesis Collection

Infants with neurological disabilities, such as cerebral palsy (CP) and Down syndrome (DS), show severe delays in motor and cognitive development relative to chronological age. Involvement of neural plasticity as a treatment of such neurological disorders is increasingly being seen. Previous studies have found that interventions involving sensory linked motor performance have been critical in facilitating motor improvement. The purpose of this study was to compare self-initiated mobility in children with CP and DS. Three infants, ages 8, 9, and 22 months, with diagnoses of no CP, DS, and CP respectively, participated in the study. The infants were videotaped in …


Antidepressant Drugs Appear To Enhance Cocaine-Induced Toxicity, Laura O'Dell Jan 2000

Antidepressant Drugs Appear To Enhance Cocaine-Induced Toxicity, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Molecular Mechanisms Mediating Genetic Sensitivity To Cocaine-Induced Convulsions., Laura O'Dell Jan 2000

Molecular Mechanisms Mediating Genetic Sensitivity To Cocaine-Induced Convulsions., Laura O'Dell

Selected Works Temporary Series

No abstract provided.


The Role Of Serotonin2 Receptors In Mediating Cocaine-Induced Convulsions, Laura O'Dell Jan 2000

The Role Of Serotonin2 Receptors In Mediating Cocaine-Induced Convulsions, Laura O'Dell

Selected Works Temporary Series

No abstract provided.


The Role Of Serotonin2 Receptors In Mediating Cocaine-Induced Convulsions, Laura O'Dell Jan 2000

The Role Of Serotonin2 Receptors In Mediating Cocaine-Induced Convulsions, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Eph Receptors And Ephrins, Masaru Nakamoto Jan 2000

Eph Receptors And Ephrins, Masaru Nakamoto

Biology Faculty Publications

The Eph receptors are the largest known family of receptor tyrosine kinases. The Eph receptors and theirmembrane-attached ligands, ephrins, show diverse expression patterns during development. Recent studies havedemonstrated that Eph receptors and ephrins play important roles in many developmental processes, includingneuronal network formation, the patterning of the neural tube and the paraxial mesoderm, the guidance of cellmigration, and vascular formation. In the nervous system, Eph receptors and ephrins have been shown to act aspositional labels to establish topographic projections. They also play a key role in pathway ®nding by axons andneural crest cells. The crucial roles of Eph receptors and …


Antidepressant Drugs Appear To Enhance Cocaine-Induced Toxicity, Laura O'Dell Jan 2000

Antidepressant Drugs Appear To Enhance Cocaine-Induced Toxicity, Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Molecular Mechanisms Mediating Genetic Sensitivity To Cocaine-Induced Convulsions., Laura O'Dell Jan 2000

Molecular Mechanisms Mediating Genetic Sensitivity To Cocaine-Induced Convulsions., Laura O'Dell

Departmental Papers (Psych)

No abstract provided.


Behavioral Effects Of Psychomotor Stimulant Infusions Into Amygdaloid Nuclei., Laura O'Dell Jan 1999

Behavioral Effects Of Psychomotor Stimulant Infusions Into Amygdaloid Nuclei., Laura O'Dell

Selected Works Temporary Series

No abstract provided.


Serotonin2c Receptors Appear To Mediate Genetic Sensitivity To Cocaine-Induced Convulsions, Laura O'Dell Jan 1999

Serotonin2c Receptors Appear To Mediate Genetic Sensitivity To Cocaine-Induced Convulsions, Laura O'Dell

Selected Works Temporary Series

No abstract provided.