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Full-Text Articles in Virology
A Deterministic Model For Understanding Nonlinear Viral Dynamics In Oysters, Qubin Qin, Jian Shen, Kimberly S. Reece
A Deterministic Model For Understanding Nonlinear Viral Dynamics In Oysters, Qubin Qin, Jian Shen, Kimberly S. Reece
VIMS Articles
Contamination of oysters with a variety of viruses is one key pathway to trigger outbreaks of massive oyster mortality as well as human illnesses, including gastroenteritis and hepatitis. Much effort has gone into examining the fate of viruses in contaminated oysters, yet the current state of knowledge of nonlinear virus-oyster interactions is not comprehensive because most studies have focused on a limited number of processes under a narrow range of experimental conditions. A framework is needed for describing the complex nonlinear virus-oyster interactions. Here, we introduce a mathematical model that includes key processes for viral dynamics in oysters, such as …
Virus Shedding Kinetics And Unconventional Virulence Tradeoffs, Andrew R. Wargo, Gael Kurath, Robert J. Scott, Benjamin Kerr
Virus Shedding Kinetics And Unconventional Virulence Tradeoffs, Andrew R. Wargo, Gael Kurath, Robert J. Scott, Benjamin Kerr
VIMS Articles
Tradeoff theory, which postulates that virulence provides both transmission costs and benefits for pathogens, has become widely adopted by the scientific community. Although theoretical literature exploring virulence-tradeoffs is vast, empirical studies validating various assumptions still remain sparse. In particular, truncation of transmission duration as a cost of virulence has been difficult to quantify with robust controlled in vivo studies. We sought to fill this knowledge gap by investigating how transmission rate and duration were associated with virulence for infectious hematopoietic necrosis virus (IHNV) in rainbow trout (Oncorhynchus mykiss). Using host mortality to quantify virulence and viral shedding to …
Transmission Of Panulirus Argus Virus 1 (Pav1) And Its Effect On The Survival Of Juvenile Caribbean Spiny Lobster, Mark J. Butler, Donald C. Behringer, Jeffrey D. Shields
Transmission Of Panulirus Argus Virus 1 (Pav1) And Its Effect On The Survival Of Juvenile Caribbean Spiny Lobster, Mark J. Butler, Donald C. Behringer, Jeffrey D. Shields
VIMS Articles
The Caribbean spiny lobster Panulirus argus, an important fisheries species, is host to Panulirus argus virus 1 (PaV1), a lethal, unclassified virus—the first found in any species of lobster— prevalent in juvenile lobsters. We describe a series of laboratory experiments aimed at assessing the likely modes of disease transmission, determining the survival of lobsters relative to each transmission pathway and identifying potential alternate hosts. Given evidence for lower prevalence of PaV1 in large lobsters, the effect of lobster size on susceptibility was also examined. Results demonstrated that PaV1 can be transmitted to juvenile lobsters via inoculation, ingestion of diseased tissue, …