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Full-Text Articles in Virology
Hiv-1-Induced Cell-Cell Fusion: Host Regulation And Consequences For Viral Spread, Menelaos Symeonides
Hiv-1-Induced Cell-Cell Fusion: Host Regulation And Consequences For Viral Spread, Menelaos Symeonides
Graduate College Dissertations and Theses
Human immunodeficiency virus type 1 (HIV-1) is a human retrovirus of the lentivirus subgroup which primarily infects T cells and macrophages, and causes acquired immune deficiency syndrome (AIDS). Since its emergence in the early 1980s, HIV-1 has caused a global pandemic which is still responsible for over one million deaths per year, primarily in sub-Saharan Africa.
HIV-1 has been the subject of intense study for over three decades, which has resulted not only in major advances in cell biology, but also in numerous drug treatments that effectively control the infection. However, cessation of treatment always results in reemergence of the …