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Hell's Tails: Localizing The Tail Proteins Of The Hyperthermophile-Infecting Virus Ssv1, Jane Arterberry
Hell's Tails: Localizing The Tail Proteins Of The Hyperthermophile-Infecting Virus Ssv1, Jane Arterberry
University Honors Theses
The tail of Saccharolobus spindle-shaped virus 1 (SSV1) has long been thought to be composed solely of viral protein 4 (VP4), but recent SSV1 structural studies have implicated the presence of additional structural proteins C166 and B78 in SSV1's unique tail. The exact locations of these proteins have not been confirmed. Structural proteins VP4 (C-terminus) and B78 are hypothesized to contribute to an adapter region bridging the viral capsid to the tail, whereas C166 is thought to comprise the majority of an internal extended structure, respectively. SSV1 structural proteins lack cysteine residues providing targets to determine their locations in the …