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Full-Text Articles in Virology
Presence Of Porcine Endogenous Retrovirus C In Domestic Pigs In Kansas, Avery Welton, Eric T. Gillock
Presence Of Porcine Endogenous Retrovirus C In Domestic Pigs In Kansas, Avery Welton, Eric T. Gillock
SACAD: John Heinrichs Scholarly and Creative Activity Days
There is currently a shortage of organs available to perform allotransplants in humans, prompting the exploration of xenotransplantation as an alternative. Xenotransplantation is the transplantation of living tissues between different species, with porcine tissues being a promising option. However, concerns arise regarding cross-species transmission, particularly in relation to Porcine Endogenous Retroviruses (PERVs). PERVs are retroviruses that are integrated into the germ-line cells of pigs and are permanently embedded in the host cell’s DNA, allowing for vertical transmission. Of significant concern is the infectious nature of two PERV subtypes, A and B, to humans, which can potentially recombine with the third …