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Full-Text Articles in Virology
Reviews Of Science For Science Librarians: The Challenge Of The Zika Virus: An Emerging Arbovirus Disease, Frances A. Delwiche
Reviews Of Science For Science Librarians: The Challenge Of The Zika Virus: An Emerging Arbovirus Disease, Frances A. Delwiche
University Libraries Faculty and Staff Publications
First identified in Uganda in 1947, the Zika virus simmered quietly for sixty years, occasionally causing a mild dengue-like illness across parts of central Africa and equatorial Asia. However, since 2007, three large outbreaks have occurred: first in Micronesia, then in French Polynesia in 2013-2014, and as an epidemic involving Mexico, the Caribbean, and Central and South America in 2015-2016. This paper reviews the virology of the Zika virus, its modes of transmission, symptoms of Zika Virus Disease, the association of Zika infections with microcephaly and Guillain-Barre Syndrome, prevention of Zika infections, and ongoing efforts to develop a vaccine.
Determining The Role Of The Ergic-53 Cargo Receptor Complex In Arenavirus Propagation, Joseph P. Klaus
Determining The Role Of The Ergic-53 Cargo Receptor Complex In Arenavirus Propagation, Joseph P. Klaus
Graduate College Dissertations and Theses
Arenaviruses and hantaviruses are human pathogens that cause significant morbidity and mortality. The current lack of vaccines and treatment options for these viruses is a global concern. Despite producing only 4 proteins, these viruses are able to maintain a persistent and asymptomatic infection in wild rodents while being continuously shed into the environment. In humans, these viruses cause a spectrum of diseases ranging from aseptic meningitis to severe hemorrhagic fever syndromes. Little is known about how arenavirus and hantavirus proteins engage and interact with the human proteome during the complex process of viral biogenesis, or how the interactions with human …