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Full-Text Articles in Virology

Detection Of Panulirus Argus Virus 1 In Caribbean Spiny Lobsters, Megan M. Montgomery-Fullerton, Roland Cooper, Kathryn M. Kauffman, Jeffrey D. Shields, Robert E. Ratzlaff Oct 2015

Detection Of Panulirus Argus Virus 1 In Caribbean Spiny Lobsters, Megan M. Montgomery-Fullerton, Roland Cooper, Kathryn M. Kauffman, Jeffrey D. Shields, Robert E. Ratzlaff

Roland A. Cooper

Panulirus argus Virus 1 (PaV1) is a pathogenic virus that infects Caribbean spiny lobsters P. argus in the Florida Keys. We have developed a PCR detection assay for PaV1 for the purpose of studying the natural history of the virus and for monitoring the prevalence of infection. The detection of the virus in hemolymph and other tissues is based on the PCR amplification of a 499 bp product using specific primers designed from a cloned fragment of the PaV1 genome. The sensitivity limit for the assay was 1.2 fg of purified viral DNA. The PaV1 primers did not react with …


Socioeconomic Characteristics And Perceptions Of Cattle Keepers And Constraints To Cattle Production In Western Kenya, Joshua O. Amimo, S Thumbi, B O. Inyangala, J O. Junga, R O. Mosi Jan 2011

Socioeconomic Characteristics And Perceptions Of Cattle Keepers And Constraints To Cattle Production In Western Kenya, Joshua O. Amimo, S Thumbi, B O. Inyangala, J O. Junga, R O. Mosi

Joshua O Amimo

No abstract provided.


Factors Influencing Reproductive Performance Of Cows From Different Nguni Ecotypes In Southern Mozambique, S Maciel, O Mwai, Joshua O. Amimo, S Moyo, M Scholtz, F Neser, M Martins Jan 2011

Factors Influencing Reproductive Performance Of Cows From Different Nguni Ecotypes In Southern Mozambique, S Maciel, O Mwai, Joshua O. Amimo, S Moyo, M Scholtz, F Neser, M Martins

Joshua O Amimo

No abstract provided.


The Effects Of Non-Genetic Factors And Estimation Of Genetic And Phenotypic Parameters And Trends For Milk Yield In Ayrshire Cattle In Kenya, Joshua O. Amimo, J W. Wakhungu, B O. Inyangala, R O. Mosi Jan 2007

The Effects Of Non-Genetic Factors And Estimation Of Genetic And Phenotypic Parameters And Trends For Milk Yield In Ayrshire Cattle In Kenya, Joshua O. Amimo, J W. Wakhungu, B O. Inyangala, R O. Mosi

Joshua O Amimo

No abstract provided.


An Assessment Of The Efficiency Of The Dairy Bull Dam Selection Methodology In Kenya, J Ombura, J W. Wakhungu, R O. Mosi, Joshua O. Amimo Jan 2007

An Assessment Of The Efficiency Of The Dairy Bull Dam Selection Methodology In Kenya, J Ombura, J W. Wakhungu, R O. Mosi, Joshua O. Amimo

Joshua O Amimo

No abstract provided.


Phenotypic And Genetic Parameters Of Reproductive Traits For Ayrshire Cattle On Large-Scale Farms In Kenya, Joshua O. Amimo Jan 2006

Phenotypic And Genetic Parameters Of Reproductive Traits For Ayrshire Cattle On Large-Scale Farms In Kenya, Joshua O. Amimo

Joshua O Amimo

No abstract provided.


Phosphorothioate Di- And Trinucleotides As A Novel Class Of Anti-Hepatitis B Virus Agents, R. P. Iyer, Y. Jin, A. Roland, John D. Morrey, S. Mounir, B. Korba Jan 2004

Phosphorothioate Di- And Trinucleotides As A Novel Class Of Anti-Hepatitis B Virus Agents, R. P. Iyer, Y. Jin, A. Roland, John D. Morrey, S. Mounir, B. Korba

John D. Morrey

Several nucleoside analogs are under clinical development for use against hepatitis B virus (HBV). Lamivudine (3TC), a nucleoside analog, and adefovir dipivoxil (ADV), an acyclonucleotide analog, are clinically approved. However, long-term treatment can induce viral resistance, and following the cessation of therapy, viral rebound is frequently observed. There continues to be a need for new antiviral agents with novel mechanisms of action. A library of more than 600 di- and trinucleotide compounds synthesized by parallel synthesis using a combinatorial strategy was screened for potential inhibitors of HBV replication using the chronically HBV-producing cell line 2.2.15. Through an iterative process of …