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Pathogenic Microbiology Commons

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Full-Text Articles in Pathogenic Microbiology

Investigation Of Host Responses Upon Infection Of Distinct Toxoplasma Strains, Rachel Devonne Hill Dec 2011

Investigation Of Host Responses Upon Infection Of Distinct Toxoplasma Strains, Rachel Devonne Hill

Doctoral Dissertations

Toxoplasma gondii is the causative agent of Toxoplasmosis in human and animals. T. gondii isolates are highly diverse. Hundreds of genotypes have been identified, but only three clonal lineages, namely Type I, II and III are prevalent worldwide. In mouse model, T. gondii strains can be divided into three groups based on their virulence, including the virulent (LD100=1), the intermediately virulent (LD50 = 103-104) and the non virulent (LD50 > 105). The clonal Type I, II and III T. gondii strains belong to these three groups, respectively. Epidemiologic studies suggest the …


Evaluation Of Chromosomally-Integrated Luxcdabe And Plasmid-Borne Gfp Markers For The Study Of Localization And Shedding Of Stec O91:H21 In Calves, Yingying Hong May 2011

Evaluation Of Chromosomally-Integrated Luxcdabe And Plasmid-Borne Gfp Markers For The Study Of Localization And Shedding Of Stec O91:H21 In Calves, Yingying Hong

Masters Theses

Shiga toxin-producing Escherichia coli (STEC) has been recognized as an important foodborne pathogen. Of this group, O91 is one of the common serogroups frequently isolated from patients and food in some countries, with O91:H21 being previously implicated in hemolytic uremic syndrome (HUS). Cattle are principle reservoirs for STEC, and studies examining STEC shedding in cattle often include experimental inoculation of strains of interest using antibiotic resistance markers for identifiable recovery. However, indigenous fecal microbes exhibiting similar resistance patterns can confound such studies. Such was the case in a study by our group when attempting to characterize shedding patterns of O91:H21 …