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Full-Text Articles in Pathogenic Microbiology
The Effect Of Diet On Midgut And Resulting Changes In Infectiousness Of Acmnpv Baculovirus In Trichoplusia Ni, Elizabeth Chen
The Effect Of Diet On Midgut And Resulting Changes In Infectiousness Of Acmnpv Baculovirus In Trichoplusia Ni, Elizabeth Chen
Electronic Thesis and Dissertation Repository
The cabbage looper, Trichoplusia ni, a global generalist lepidopteran pest, has developed resistance to many synthetic and biological insecticides, requiring effective and environmentally acceptable alternatives. One possibility is the Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV). This baculovirus is highly infectious for T. ni, with potential as a biocontrol agent, however, its effectiveness is strongly influenced by dietary context. In this study, microscopy and transcriptomics were used to examine how the efficacy of this virus was affected when T. ni larvae were raised on different diets. Larvae raised on potato host plants had lower chitinase and chitin deacetylase transcript levels …
Examination Of Bcaa Transport And Synthesis In Staphylococcus Aureus, Julienne Kaiser
Examination Of Bcaa Transport And Synthesis In Staphylococcus Aureus, Julienne Kaiser
Electronic Thesis and Dissertation Repository
Staphylococcus aureus is a human pathogen capable of causing infections that range from mild skin and soft tissue infections to severe infections of the bone, muscle, heart, and lung. To survive and thrive in such diverse host environments, S. aureus must maintain sufficient levels of metabolites and cofactors to support virulence determinant production and replication. The branched-chain amino acids (BCAAs; Ile, Leu, Val) represent an important group of nutrients for S. aureus metabolism, as they are required for protein synthesis and synthesis of membrane branched-chain fatty acids (BCFAs), which are important for S. aureus environmental adaptation. Moreover, the BCAAs are …