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Full-Text Articles in Pathogenic Microbiology
A Rapid Viability And Drug‑Susceptibility Assay Utilizing Mycobacteriophage As An Indicator Of Drug Susceptibilities Of Anti‑Tb Drugs Against Mycobacterium Smegmatis Mc2 155, Gillian Catherine Crowley, Jim O'Mahony, Aidan Coffey, Riona G. Sayers, Paul D. Cotter
A Rapid Viability And Drug‑Susceptibility Assay Utilizing Mycobacteriophage As An Indicator Of Drug Susceptibilities Of Anti‑Tb Drugs Against Mycobacterium Smegmatis Mc2 155, Gillian Catherine Crowley, Jim O'Mahony, Aidan Coffey, Riona G. Sayers, Paul D. Cotter
Department of Biological Sciences Publications
Background: A rapid in-house TM4 mycobacteriophage-based assay, to identify multidrug resistance against various anti-tuberculosis drugs, using the fast-growing Mycobacterium smegmatis mc2 155 in a microtiter plate format was evaluated, based on phage viability assays. Methods: A variety of parameters were optimized before the study including the minimum incubation time for the drugs, phage and M. smegmatis mc2 155 to be in contact. An increase in phage numbers over 2 h was indicative that M. smegmatis mc2 155 is resistant to the drugs under investigation, however when phage numbers remained static, M. smegmatis mc2 155 found to …
An Ecotypic Differentiation Of Human And Bovine Fecal Streptococci, With Application To Human Pollution In The Yakima River, Harlen Harvey Johnson
An Ecotypic Differentiation Of Human And Bovine Fecal Streptococci, With Application To Human Pollution In The Yakima River, Harlen Harvey Johnson
All Master's Theses
It was the purpose of this study to report on the development of a technique for distinguishing human fecal streptococci from bovine fecal streptococci, and to make application of this technique in describing some of the sources of pollution in the Yakima River as contributed by the Wilson Creek drainage system, in the Ellensburg area of Washington.