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Full-Text Articles in Pathogenic Microbiology
Helicobacter Pylori Gene Regulation By Virulence Region Located Srnas, Veronica Janette Albrecht
Helicobacter Pylori Gene Regulation By Virulence Region Located Srnas, Veronica Janette Albrecht
EWU Masters Thesis Collection
Approximately 50% of the human population is infected with Helicobacter pylori, which can lead to gastrointestinal diseases such as ulcers and gastric adenocarcinoma. Helicobacter pylori strains are genetically variable, and some contain a DNA region called the cytotoxin associated gene pathogenicity island (cagPAI) that encodes virulence factors. Gastrointestinal disease associated with H. pylori are more likely to occur in infections with cagPAI positive strains. Helicobacter pylori has few known transcriptional regulators, but still must regulate expression to survive a constantly changing environment. A mechanism to facilitate this regulation was revealed in a transcriptome analysis conducted by Sharma et al. (2010) …
Impact Of Chytrid Fungus Pathogen On The Skin Microbiome Of Frogs In Northern Idaho And Turnbull National Wildlife Refuge, Washington, Philip M. Campos
Impact Of Chytrid Fungus Pathogen On The Skin Microbiome Of Frogs In Northern Idaho And Turnbull National Wildlife Refuge, Washington, Philip M. Campos
EWU Masters Thesis Collection
Amphibians worldwide are under threat from the infectious disease chytridiomycosis, which is caused by the chytrid fungus Batrachochytrium dendrobatidis (Bd). Bd is associated with the population declines of an estimated 501 species, 90 of which are presumed or confirmed extinct, making this the greatest documented loss of biodiversity attributed to a disease. Researching the amphibian skin microbiome may provide solutions to conservation of amphibians. Two main relationships have been observed between Bd and the microbiome: 1) bacteria producing antifungal metabolites can inhibit Bd and improve survival against the disease and 2) infection by Bd is believed to affect the composition …