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Full-Text Articles in Pathogenic Microbiology
Mupirocin Resistance In Staphylococci: An Investigation Of Current Status And Potential Alternative Therapies, Susan O'Shea
Mupirocin Resistance In Staphylococci: An Investigation Of Current Status And Potential Alternative Therapies, Susan O'Shea
Theses
Mupirocin is a topical antibiotic used in hospital infection control practices to control transmission of staphylococci, in particular MRSA, which has become a major problem in Irish hospitals and has a significant impact on patient morbidity and mortality. Overreliance on mupirocin to eradicate MRSA carriage and to prevent infection has led to mupirocin resistance among staphylococcal species. Two distinct types of resistance have developed within strains: low'-level mupirocin resistance (LMR) and high-level mupirocin resistance (HMR).
The aim of this study was to assess the prevalence and types of mupirocin resistance in a large population of clinical staphylococcal isolates including Methicillin …