Exercise Science Commons^™

Intensity-Specific Training Adaptations To Exercise In Females, Julianna P. Mereu

Undergraduate Student Research Internships Conference

Previous studies examining the effects of exercise training on metabolism have primarily used males as participants. It has been shown that as little as one hour of aerobic exercise in males leads to the alteration of several metabolic enzymes, including phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphate (G6Pase). Changes in glycogen content and differences in the usage of glycogen for fuel following exercise training have also been shown in male rats. However, it is unclear whether females demonstrate the same training related metabolic adaptations as males.

Therefore, the purpose of this project was to examine various metabolic responses to an acute exercise …

The Effect Of Type 1 Diabetes On The Metabolic Response To Exercise, Theres Tijo

Undergraduate Student Research Internships Conference

Type 1 Diabetes Mellitus (T1DM) is an autoimmune disorder that results in insufficient endogenous insulin production. Regular exercise has numerous health benefits for individuals with T1DM, however, most insulin-dependent diabetics avoid physical activity due to the fear of exercise-induced hypoglycemia (low blood glucose/BG).

The risk of hypoglycemia in this population may be partly due to lower liver glycogen stores which is a major source of blood glucose during exercise. However, the mechanism that leads to lower glycogen stores in T1DM is unknown.

The purpose of this study was to determine the effect of an acute bout of moderate-intensity aerobic exercise …

Cancer Cachexia: Metabolic Changes That Occur In Oxidative Capacity And Carbohydrate And Lipid Metabolism Of The Liver, Sarah Ramey

Health, Human Performance and Recreation Undergraduate Honors Theses

BACKGROUND: Cancer cachexia is defined as cancer-associated muscle wasting, and is a cancer side effect that dramatically affects cancer prognosis, is thought to be at least partially mediated by increased energy expenditure, and is directly responsible for the death of 20-40% of all cancer patients. Although the liver is known to be a predominant regulator of whole body metabolism, there is little known about its relationship to the development of cancer cachexia. PURPOSE: The purpose of this exploratory study was to investigate alterations in liver metabolism by examining measures of hepatic glycogen storage, oxidative phenotype and lipid content throughout the …