Exercise Science Commons^™

Global Mitophagy Inhibition Via Bnip3 Ablation Is Not Sufficient To Alleviate Skeletal Muscle Impairments In Male And Female Tumor-Bearing Mice, Francielly Morena, Ana Regina Cabrera, Toby L. Chambers, Pietier J. Koopmans, Seongkyun Lim, Stavroula Tsitanou, Sabin Khadgi, Calvin Peterson, Eleanor R. Schrems, Ruqaiza Muhyudin, Sepideh Shakeri, Kevin Zhao, Devan Mishra, Tyrone Washington, Kevin A. Murach, Nicholas P. Greene

Health, Human Performance and Recreation Faculty Publications and Presentations

Cancer cachexia (CC) is marked by severe skeletal muscle loss and dysfunction, associated with mitochondrial degeneration. Our previous studies showed induction of the mitophagy marker BNIP3 3-wk post-Lewis lung carcinoma (LLC) induction. We hypothesize that excessive mitophagy contributes to muscle wasting in CC. To test this, we used a Bnip3 knockout (KO) mouse model with LLC-induced CC to assess its impact on muscle outcomes. Eight-wk-old male and female mice were injected with 1 x 10(6) LLC cells or PBS (sham controls). After 4 wk, we assessed muscle function through dorsiflexor electrophysiology, muscle protein synthesis via deuterium oxide labeling, and mitochondrial …

The N-Pact Factor, Replication And Power Associated With Quantitative Research In Physical Activity And Health, Angelina Haidar, Jeffrey J. Martin, Adam J. Martin, Sarah Rogers, Fatemeh Dehghan, Eva Prokesova

International Journal of Physical Activity and Health

Physical Activity (PA) and health science researchers often face challenges related to sample size, which can impact the reliability and generalizability of study findings. The purpose of the current paper is to address these issues by discussing key statistical concepts: effect size and Type I and Type II errors, with a specific focus on examining statistical power and sample size using studies from the Disability and Health Journal (DHJ). We examined research articles published in DHJ over a 15-year period (2008–2022), covering 62 issues and analyzing a total of 1,177 articles. Our analysis revealed that the median sample sizes …

Associations Between 24-Hour Movement Compositions And Cardiometabolic Health In Children And Adolescents: A Five-Part Compositional Analysis Using Data From The International Children’S Accelerometery Database (Icad), Zoë A. Marshall, Adam Runacres, Pedro Curi Hallal, Russ Jago, Soyang Kwon, Kate Northstone, Russell R. Pate, Jardena Puder, John J. Reilly, Luis B. Sardinha, Niels Wedderkopp, Ester Van Slujis

Faculty Publications

Objectives The benefits of physical activity (PA) and the negative impacts of sedentary time (SED) on health in youth are well established. However, uncertainty remains surrounding how PA and SED jointly influence cardiometabolic risk (CMR) factors. The aim of this study was to determine the joint influence of SED, light-, moderate- and vigorous-intensity PA (LPA, MPA and VPA), and sleep on CMR factors using five-part compositional analyses.

Methods Data were pooled from 16 cohort studies comprising 22 474 children and adolescents from the International Children’s Accelerometery Database. PA was measured using hip-mounted accelerometers with sleep self-reported. CMRs included body mass …

Assessment Of Walkability Of University Campus And Communities: Associations With Perceived Safety & Student Retention, Wendy Bjerke

Exercise Science Faculty Publications

Introduction: Approximately 80% of Americans do not meet minimum guidelines for regular physical activity. Among ways to promote physical activity is to optimize the Built Environment to promote and increase access to walking and cycling. Walkable and accessible university campus environments and proximal communities can promote physical activity and are assessed and compared in this study. Purpose and Methods: Approximately 20 million students attend colleges and universities in the United States with over 100,000 students enrolled in the state of Connecticut. These students can potentially engage in physical activity within a campus or around the surrounding communities for university related …

Voluntary Contractions Underestimate Peak Muscle Activity In Drop Jumps, David Alan Phillips, Skylar Paletta, Michael R. Perlet

Department of Kinesiology Scholarship and Creative Works

Maximal voluntary isometric contractions (MVIC) are a common method to normalize electromyographic amplitude into standardized units of %MVIC. However, in 60% of drop jump research using an MVIC in 2018–2023, supramaximal activation or activation greater than 100% MVIC occurred. Therefore, MVICs may not be representative of peak muscle activation, leading to erroneous interpretation of muscle activation. The purpose of this study is to quantify EMG normalization difference in drop jump landings. Sixteen (10 M, 6F) participants were recruited for the study. MVICs were recorded from nine lower extremity muscles and this activation compared to the maximal activation recorded from 10 …

Behavioral And Neural Correlates Of Post-Stroke Fatigue: A Randomized Controlled Trial Protocol, Kuan-Chun Liao, Isabellle Christian, Jill C. Stewart, Elaine Trudelle-Jackson, Wanyi Wang, Ty Shang, Hui-Ting Goh

Faculty Publications

Introduction

Post-stroke fatigue (PSF) is highly prevalent and lacks of effective management. Recent evidence suggest the use of transcranial direct current stimulation (tDCS) to reduce PSF. However, the effect was not lasting and the working mechanisms was unclear. The purpose of this study is to determine the behavioral and neurophysiological effects of five daily sessions of tDCS on PSF.

Methods and analysis

This will be a double-blind randomized controlled trial targeting an enrollment of 32 participants with subacute-chronic stroke and significant fatigue (average Fatigue Severity Scale (FSS) > 4). Participants will be equally randomized to either anodal tDCS or sham tDCS …

Effect Of In-Season Potentiation And Priming On Jump Height In Collegiate D1 American Football Players, Benjamin Dagostino, Kody Cooke, Paulette Yamada, Trevor Short

Topics in Exercise Science and Kinesiology

Neuromuscular priming and post-activation potentiation (PAP) are techniques utilized to increase nervous system excitation, muscle force, and rate of force development during subsequent muscle contractions in sport. PAP is a commonly used approach that has the potential to influence neuromuscular status monitoring and flagging, and optimize power training. Specifically, jump height is an important parameter in athletic performance and assessing inter-limb asymmetries. Thus, the purpose of this paper is to report the effects of different PAP strategies on jump height during a competitive D1 American football season. These findings will inform practitioners on optimal PAP strategies and their implications …

Proceedings From The Sixth Annual Society For Sports Neuroscience Conference, Neurosports Editorial Staff

Journal for Sports Neuroscience

Proceedings from the Sixth Annual Society for Sports Neuroscience Conference

Walk A Mile: Exploring Cause-Based Charity Event Participation As A Catalyst For Increasing Physical Activity Behavior, Kimberly S. Fasczewski, Andrey A. Sanko Posada, Meg Hopkins

Journal of Social, Behavioral, and Health Sciences

Despite the known benefits of physical activity (PA), more than half of U.S. adults do not meet the American College of Sports Medicine’s PA recommendations for health, often resulting in negative health outcomes. Developing programming that increases motivation for PA participation is critical for healthcare professionals to combat physical inactivity. Previous research has demonstrated that framing disease-based PA charity fundraising events as “helping a cause” improved motivation for PA due to the individual’s emotional connection to the cause. There is currently no congruent research on motivation for participation in cause-based charity events. Behavioral economics theory posits that cognitive, emotional, and …

Physical Activity And Body Image In Early Onset Cancer Patients, Madeleine Z. Pollard

Graduate Masters Theses

Abstract: Cancer is the leading cause of death among Americans under the age of 85 (Brown et al., 2012). There are increasing rates of cancer diagnoses in adults aged 18-49, which is described as an early onset (EO) diagnosis. Despite high survival rates (Lewis et al., 2021), EO cancer patients are at increased risk for long-term physical and psychological challenges associated with both the disease and its treatment (Haque et al., 2023). Cancer diagnosed during these critical periods of life can significantly impact self-perception and body image, which are critical to identity formation and quality of life (Castonguay, et al., …

Aging-Induced Increase In Top-Down Connectivity From Dlpfc To Sma/M1 And Decrease In Inter-Limb Motor Coordination During Standing Tasks, Jiahao Pan, Shuqi Zhang

International Journal of Physical Activity and Health

This study aimed to investigate the effects of aging on inhibitory control from the prefrontal cortex (PFC) to the motor cortices and inter-limb coordination during dual task standing. Participants performed single-task and dual-task standing. Ground reaction force, center-of-pressure, muscle activity, and cortical activation were measured. The older group showed a greater effective connectivity index from the intra-hemispheric dorsolateral PFC (DLPFC) to supplementary motor area (SMA) (right, p = 0.009; left, p = 0.003) and left DLPFC to right M1 (p = 0.020)than the young group across task conditions. Also, the older group had greater inter-tibialis anterior coherence at 15–35 …

It Is Not Clear How Well Physical Activity Promotion Materials Are Understood: Findings From A Rapid Literature Review, Jafra D. Thomas, Jasmine C. Wong, Regina F. Hockert, Yi Sheng Wu, Winston Kennedy

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 6: Issue 1, Article 6, 2025. Efforts to promote physical activity and other health-related behaviors are more effective when resource materials are understood by a wide and diverse audience. Before our lab’s previous investigations (Thomas et al., 2024), only one study seemed to use the cloze procedure to directly test the comprehension (i.e., readability) of physical activity promotion material (Cardinal & Seidler, 1995). Thus, this rapid literature review sought to (a) determine the extent the cloze procedure has been used to study physical activity promotion material comprehension in lay adults and (b) collate …

A Description Of Mental Health Policies In Ohio Secondary Schools, Laura L. Harris, Molly Rowe

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE To compare secondary school mental health policies implemented for the student body with those implemented for student athletes.

Athletic Trainers Confidence In Evaluating And Treating Emergent Conditions, Andrea Cripps, Jenny Toonstra, Sara Stiltner

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE The profession of Athletic Training (AT) has undergone a substantial educational overhaul in the last decade, adding more advanced knowledge and skills than ever before. With more than 50% of the profession having obtained their certification more than 10 years prior,¹ it is essential that we understand the varying levels of confidence in evaluating and managing these new skills, so that appropriate continuing education opportunities can be developed to bridge any gaps that may be identified. The purpose of this study to examine self-reported confidence in evaluating and managing acute care skills.

Sternocleidomastoid Syndrome In A Collegiate Basketball Athlete: A Case Study, Sara Stiltner, Rob Whitehurst, Eric Avers

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

BACKGROUND
20-year-old male basketball athlete with recurring upper and lower extremity instability injuries presented fall 2021 with shoulder and ankle instability. A past medical history of thermal capsulorrhaphy from high school with surgical intervention May 2021 (college first year). October 2021 athlete began experiencing rotator cuff strains in both shoulders. November 2021, December 2021, January 2022 athlete experiences recurrent right ankle sprains. Each ankle sprain resulted in two weeks of lost participation, followed by one week of active participation. The third ankle sprain associated with increased swelling and pain over medial ankle. Upon referral and MRI a deltoid ligament sprain …

Causes Of Athletic Trainer Attrition: A Critically Appraised Topic, Mckenna E. Tuttle, Klevione D. Brown, Elizabeth A. Starns

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Athletic Training (AT) attrition has been a persistent issue within the profession for years^1,2. By identifying the factors contributing to the attrition rates among Athletic Trainers, targeted interventions can be developed to mitigate turnover and decrease attrition within the profession.

Kinematic Analysis Of Lower Extremity Movement Patterns During Functional Tests In Collegiate Track And Field Runners To Predict Injury Incidence, Maddie Hoyt, Brooke Parker, Bailey Weise, Andrew Busch

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE
Lower extremity overuse injuries are becoming increasingly more prevalent in endurance-based running sports^1,2,3,4,5,6. These injuries negatively impact an athlete’s sports performance and increase the risk of additional injuries^3,4. The purpose of this study was to first examine kinematic and kinetic variables within distance runners and compare those with previous lower extremity injuries to those without reported injuries; and second to understand if such variables predicted future injuries sustained throughout a track season.

Injury Epidemiology In Collegiate Marching Band, Morgan Davis, Jinghzen Yang, Matthew Brancaleone

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE
Marching bands have become more popular and physically demanding, with performers taking up to 16,174 steps on game days, which may increase their risk of musculoskeletal injuries. However, research on these performers remains limited. The purpose of this study was to describe the incidence of reported injury and pain and soreness experienced by marching artists within a collegiate marching band.

Atypical Anterior Tibial Stress Fracture Leading To Acute Fracture And Intermedullary Rodding, Emily Mulkey Swisher, Chad Cochran, Raymond Duffett

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE
This case highlights an unusual stress fracture progressing to an acute tibial fracture requiring intermedullary rodding.

The Athletic Trainer's Responsibility In Disability Exercise Adherence, Elizabeth Starns, Stephanie M. Kubiak, Rebecca J. Wehler

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE
This study examined exercise adherence to aerobic and strength training exercise guidelines in individuals with disabilities, highlighting the implications for athletic training (AT). Because disabilities impact over 25% of the U.S. population¹, an understanding of the varied exercise adherence patterns can inform inclusive AT best practices and assist in promoting exercise and sport participation.

Emergency Action Planning In Collegiate Athletics: An Evaluation Of The Current Adoption Of Best Practice Recommendations, Kyler Conn, Ken Blood, Genna Fusco

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE
The primary objective of this study was to assess the current adoption of the National Athletic Trainers’ Association’s (NATA) best practice recommendations regarding emergency planning, outlined in the NATA Position Statement: Emergency Planning in Athletics, at the collegiate level.

Effect Of Hearing Status On Modified Balance Error Scoring System Performance, Matthew Brancaleone, Claire Akard, Jaclyn Caccese

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE
Concussion assessments typically include evaluations of self-reported symptoms, neurocognitive function, and postural control. Specifically, postural control is often assessed using the modified Balance Error Scoring System (mBESS). Although normative mBESS data exist, they may not be appropriate for all athletes, such as those who are deaf or hard-of-hearing (D/HoH). Given the relationship between the cochlea and the vestibular system, athletes who are D/HoH may exhibit differences in postural control due to potential vestibular dysfunction. Therefore, the objective of this study was to compare mBESS performance between athletes who are D/HoH and athletes who are hearing.

Spontaneous Pneumothorax In A Male High School Wrestler, Laura Breese, Sara Stiltner

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE/BACKGROUND
A pneumothorax is the presence of air in the pleural space, it is a life threatening condition and can be classified as spontaneous, acquired, or by pathophysiology. (1)(2) This specific case presents the incident of a spontaneous pneumothorax in an adolescent population.

Effect Of Β-Alanine Supplementation On Inflammation Response And Subsequent Muscle Function Following An Acute Bout Of Resistance Training., David F. Smith

Masters Theses, 2020-current

Purpose: This study aimed to examine the effects of β-alanine supplementation on the inflammation response, as measured by Interleukin-6 (IL-6) levels, and subsequent muscle function in resistance-trained individuals following a single bout of resistance exercise.

Methods: Fourteen resistance-trained subjects were recruited for a double-blind, between-group experiment. Following a two-week washout period (if needed), subjects were randomly assigned to receive either 6.8g of β-alanine daily or a placebo. After the supplementation period, subjects performed a standardized exhaustive squat protocol (10 sets of 10 repetitions at 60% of their estimated 1RM). Venous blood samples were collected pre-exercise, 24-hours post, and 72-hours post …

Agreement Between Methods For Describing The Intensity Of A High Intensity Functional Training Workout, James W. Henley

Master's Theses

This study examined whether a speed-based metric, expressed as percent of maximal speed (%MS), could serve as a practical and accurate method for quantifying intensity in high-intensity functional training (HIFT). Traditional intensity markers—heart rate (HR), blood lactate concentration ([La-]), and rating of perceived exertion (RPE)—were compared to %MS during low- and high-volume (LV, HV) workouts using a combination of correlation and agreement analyses. Twelve males and twelve females completed a baseline assessment followed by two experimental workout sessions. Participants wore HR monitors, provided pre- and post-exercise [La-] samples and RPE scores, and performed maximal speed tests for each workout movement. …

Physical Function In Young And Older Adult Active Pickleball Players – A Cross-Sectional Study, Leighanne T. Paulson, Eric Martin, Kent Adams, Marcus M. Lawrence

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 6: Issue 1, Article 5, 2025. Limited information exists on pickleball’s impact on physical function in older adults (65+ years), despite reported health benefits. PURPOSE: This cross-sectional study evaluated the physical function of active older adult (OA) women and men recreational pickleball players via handgrip strength (HGS) and fatigue (HGF), 6-minute walk distance (6MWD) test, as well as the short physical performance battery (SPPB) compared to sex-matched young adult (YA) controls. METHODS: Thirty YA (18-26 years; n=15 women/men) and 27 OA (65-89 years; n=13 women, n=15 men) participants who played pickleball …

A History Of Omics Discoveries Reveals The Correlates And Mechanisms Of Loading-Induced Hypertrophy In Adult Skeletal Muscle. 2024 Camps Young Investigator Award Invited Review, Toby L. Chambers, Kevin A. Murach

Health, Human Performance and Recreation Faculty Publications and Presentations

Since the early 2000s, omics approaches to study skeletal muscle hypertrophy consequent to loading (e.g., resistance exercise) have expanded dramatically. Beginning with genomics and transcriptomics, there are now omics datasets from hypertrophying skeletal muscle spanning methylomics, proteomics, and phosphoproteomics, with further integration of single cell/nucleus-specific omics, among others. The purpose of this review is to explore the history of leveraging omics to enable understanding and discovery with respect to loading-induced hypertrophy in adult skeletal muscle. We elaborate on key historical and contemporary studies and findings, highlight specific examples where omics discoveries led to a mechanistic understanding of skeletal muscle growth, …

Does Limb Specialization In Track And Field Introduce Asymmetry In Dynamic Stability?, Aaron X. Jones

Master's Theses

Time to stabilization (TTS) represents the time it takes for a person to become still after a hop landing. Lower times suggest greater dynamic stability. Whereas leg dominance (preference) does not seem to have a significant impact on TTS performance in the general healthy populations, limb specialization in sport may introduce asymmetry. This study compares TTS following forward hops in healthy male controls (N = 19) to varsity DIII Track & Field athletes (N = 20). Groups were equal for height, but the athlete group’s average limb length (106.7 ± 5.5 cm) was greater than the control group (101.5 ± …

Economy Smart Watch Fails To Accurately Monitor Blood Glucose Among Healthy Adults, Thinh Le Mr., Douglas Oberlin Dr., Adam Mohan Mr.

Undergraduate Research

Monitoring and maintenance of blood glucose (BG) concentrations is of critical importance to individuals with diabetes mellitus. However, this often requires multiple finger-sticks and a glucometer, or the use of a prescription continuous glucose monitor (CGM). Recently, some smart watches have become available which claim to non-invasively monitor BG. This should not be confused with watches that pair with CGMs. The purpose of this study was to assess whether the economy smart watches were capable of detecting BG changes among healthy individuals. Currently three participants have completed this study. Healthy young adults reported to the lab after a 4-6 hour …

The Impact Of Prenatal Yoga On Hip Mobility And Delivery Outcomes, Zoe Avery

Mahurin Honors College Capstone Experience/Thesis Projects

Yoga has been shown to decrease lumbar pain, improve maternal mental health, and improve delivery outcomes. While there are many well-established benefits of yoga, the mechanism by which yoga elicits these improvements is unclear. One potential mechanism that has not been studied is through improvements in hip mobility. PURPOSE: The purpose of this study was to test the effect of prenatal yoga on hip mobility. The secondary aim was to determine the relationship between hip mobility and pregnancy outcomes. METHODS: Hip mobility via hip internal and external range of motion and hip flexor muscle length was measured in pregnant females …