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Articles 451 - 463 of 463

Full-Text Articles in Exercise Science

Role Of Satellite Cells In Long Term Fiber Type Shifts, Honglu Liu Jan 2013

Role Of Satellite Cells In Long Term Fiber Type Shifts, Honglu Liu

Lewis Honors College Capstone Collection

Muscle fiber type shifts in respect to satellite cells, muscle stem cells, are not well understood currently. The Peterson Lab has generated a mouse model (PAX7-DTA) that ablates satellite cells to determine if these muscle stem cells contribute to mouse muscle fiber type changes over an eight week period. In the study, control and satellite-cell-ablated mouse groups were split into control and overload groups (via synergist ablation surgery) and placed under similar environmental conditions. Eight weeks post-experiment, muscles were dissected to obtain the plantaris muscles of animals from all groups. Muscle cross-sections obtained were immunohistochemically stained, imaged, quantified by fiber …


Changes In In Vivo Knee Contact Forces Through Gait Modification, Allison Kinney, Thor F. Besier, Amy Slider, Scott L. Delp, Darryl D. D'Lima, Benjamin J. Fregly Aug 2012

Changes In In Vivo Knee Contact Forces Through Gait Modification, Allison Kinney, Thor F. Besier, Amy Slider, Scott L. Delp, Darryl D. D'Lima, Benjamin J. Fregly

Mechanical and Aerospace Engineering Faculty Publications

Gait modification represents a non-invasive method for reducing knee joint loading in patients with knee osteoarthritis. Previous studies have shown that a variety of gait modifications are effective in reducing the external knee adduction moment. The external knee adduction moment is often used as a surrogate measure of medial compartment force. However, a recent study showed that reductions in the external knee adduction moment do not guarantee reductions in medial compartment loads. Therefore, direct measurement of changes in knee contact force is important for determining the effectiveness of gait modifications. A previous study found that medial thrust gait and walking …


Throwing Frame For Athletes With Dissabilities, Andrew Higgins, Stefan Owechko, Gabriel (Gabe) Terrasas, Kevin Crisfield Jun 2012

Throwing Frame For Athletes With Dissabilities, Andrew Higgins, Stefan Owechko, Gabriel (Gabe) Terrasas, Kevin Crisfield

Mechanical Engineering

Team Zeus’ senior project was to design, build and test a working throwing frame system for Bridge II Sports, a nonprofit organization in North Carolina. The throwing frame is used to allow athletes and individuals with disabilities to throw shot-put, discus, and javelin using a frame to sit against. Team Zeus was specifically tasked to build a frame that is lighter weight and more transportable than products that are currently on the market. This frame also is adjustable to accommodate a wide range of athlete weights, sizes, and abilities. The final result is a 35lb aluminum frame with two different …


Effectiveness Of Group Kickboxing As A Means To Improve Gait And Balance In Individuals With Ms, Kurt Jackson, Kimberly Edginton Bigelow, Christina Cooper, Harold L. Merriman Oct 2011

Effectiveness Of Group Kickboxing As A Means To Improve Gait And Balance In Individuals With Ms, Kurt Jackson, Kimberly Edginton Bigelow, Christina Cooper, Harold L. Merriman

Mechanical and Aerospace Engineering Faculty Publications

In recent years, there has been a particular emphasis on identifying and delivering appropriate therapeutic interventions that address the significant balance and gait impairments that affect individuals with multiple sclerosis (MS). Group interventions implemented in community settings have been especially of interest, including tai chi classes. Recently, the authors conducted a preliminary study to examine whether group kick-boxing, which requires more vigorous movements, might be a feasible intervention. Initial findings showed promise and led the authors to pursue a more rigorous follow-up study, with the objective of determining whether a 5-week group kickboxing class improved clinical measures of balance and …


Muscle Contributions To Frontal And Transverse Plane Whole-Body Angular Momentum, Richard R. Neptune, Craig P. Mcgowan, Allison Kinney Jul 2011

Muscle Contributions To Frontal And Transverse Plane Whole-Body Angular Momentum, Richard R. Neptune, Craig P. Mcgowan, Allison Kinney

Mechanical and Aerospace Engineering Faculty Publications

The purpose of this study was to build upon previous work by analyzing how gravity and individual muscles contribute to frontal and traverse plane whole-body angular momentum. Identifying which muscles are responsible for generating angular momentum has important implications for the diagnosis and treatment of movement disorders.


The Effects Of Sodium Bicarbonate Supplementation On Lower-Body Hypertrophy-Type Resistance Exercise, Benjamin Mclean Carr May 2011

The Effects Of Sodium Bicarbonate Supplementation On Lower-Body Hypertrophy-Type Resistance Exercise, Benjamin Mclean Carr

Dissertations

A number of studies have demonstrated the ergogenic effects of induced-alkalosis on high-intensity intermittent exercise performance. Purpose: The aim of the present study was to examine the effects of sodium bicarbonate (NaHCO3) administration on a high-volume hypertrophy-type resistance exercise regimen for the lower body. Methods: In a double-blind counterbalanced manner, 12 resistance-trained male participants (mean ± SD; age = 20.3 ± 2 yr, mass = 88.3 ± 13.2 kg, height = 1.80 ± 0.07 m), with a minimum of two years of training experience, ingested either 0.3 g˙kg-1 of NaHCO3 or calcium carbonate (CaCO3) …


Pre-Swing Deficits In Forward Propulsion, Swing Initiation And Power Generation By Individual Muscles In Hemiparetic Walking, Carrie L. Peterson, Allison Kinney, Steven A. Kautz, Richard R. Neptune Aug 2010

Pre-Swing Deficits In Forward Propulsion, Swing Initiation And Power Generation By Individual Muscles In Hemiparetic Walking, Carrie L. Peterson, Allison Kinney, Steven A. Kautz, Richard R. Neptune

Mechanical and Aerospace Engineering Faculty Publications

Clinical studies of hemiparetic walking have shown pre-swing abnormalities in the paretic leg suggesting that paretic muscle contributions to important biomechanical walking subtasks are different than those of non-disabled individuals. Three-dimensional forward dynamics simulations of two representative hemiparetic subjects with different levels of walking function classified by self-selected walking speed (i.e., limited community=0.4–0.8 m/s and community walkers=>0.8 m/s) and a speed-matched control were generated to quantify individual muscle contributions to forward propulsion, swing initiation and power generation during the pre-swing phase (i.e., double support phase proceeding toe-off). Simulation analyses identified decreased paretic soleus and gastrocnemius contributions to forward propulsion …


Relationships Between Muscle Contributions To Walking Subtasks And Functional Walking Status In Persons With Post-Stroke Hemiparesis, Allison Kinney, Carrie L. Peterson, Steven A. Kautz, Richard R. Neptune Aug 2010

Relationships Between Muscle Contributions To Walking Subtasks And Functional Walking Status In Persons With Post-Stroke Hemiparesis, Allison Kinney, Carrie L. Peterson, Steven A. Kautz, Richard R. Neptune

Mechanical and Aerospace Engineering Faculty Publications

Walking speed is commonly used to predict stroke severity and assess functional walking status (i.e., household, limited community and community walking status) post-stroke. The underlying mechanisms that limit walking speed (and functional walking status by extension) need to be understood to improve post-stroke rehabilitation. Previous experimental studies have shown correlations between paretic plantarflexor output during the pre-swing phase and walking speed and suggest that the paretic hip flexors can compensate in some hemiparetic subjects. Modeling and simulation studies of healthy walking have shown that the ankle plantarflexors, soleus (SOL) and gastrocnemius (GAS), and uniarticular hip flexors (IL) are essential contributors …


Fabrication Of Ankle-Foot Orthoses Using Selective Laser Sintering Technology, Allison Kinney, M. C. Faustini, Richard R. Neptune, R. H. Crawford, S. J. Stanhope Jul 2007

Fabrication Of Ankle-Foot Orthoses Using Selective Laser Sintering Technology, Allison Kinney, M. C. Faustini, Richard R. Neptune, R. H. Crawford, S. J. Stanhope

Mechanical and Aerospace Engineering Faculty Publications

Passive dynamic ankle-foot orthoses (AFOs) are often prescribed to improve gait performance for those with various neuromuscular disorders. Designs and materials used for AFOs range from simple polypropylene braces to advanced custom carbon fiber dynamic AFOs that passively store and release mechanical energy during gait. AFO designs vary in the shape and length of the foot component as well as the stiffness and length of the tibial component, depending on the desired functional outcomes. However, the current fabrication technology is not ideally suited for refined customization of AFO characteristics to optimize performance, or for rapid lowcost, high volume manufacturing and …


Development And Analysis Of A Software Package To Quantify In Vivo Polyethylene Wear After Total Hip Arthroplasty, Allison Kinney, Catherine G. Ambrose Jul 2007

Development And Analysis Of A Software Package To Quantify In Vivo Polyethylene Wear After Total Hip Arthroplasty, Allison Kinney, Catherine G. Ambrose

Mechanical and Aerospace Engineering Faculty Publications

Since the first total hip arthroplasty (THA) in 1938, THA evolved and developed into one of the major concentrations of orthopaedic research. The typical hip implant device used today incorporates a femoral and an acetabular component that serve to replicate the anatomical and mechanical functions of the natural hip joint. However, several problems exist that can effect the function of the implant device. Wear in the polyethylene liner of the acetabular component of the total hip replacement device is known as one of the major factors that affects the longevity of total hip replacement devices. Both manual and computer-aided techniques …


Disaggregating The Relative Influence Of Genetic, Environmental And Individual Factors On Ldl And Hdl Cholesterols And Bmi For A Sample Of African American (Aa) Mothers And Daughters, C. Jayne Brahler, Jewel Harden, Michelle Mchone, Matthew Soules, Eric Evans, Ann Alyanak, Fred Diakpieng, Paul M. Vanderburgh Feb 2006

Disaggregating The Relative Influence Of Genetic, Environmental And Individual Factors On Ldl And Hdl Cholesterols And Bmi For A Sample Of African American (Aa) Mothers And Daughters, C. Jayne Brahler, Jewel Harden, Michelle Mchone, Matthew Soules, Eric Evans, Ann Alyanak, Fred Diakpieng, Paul M. Vanderburgh

Health and Sport Science Faculty Publications

There are many reports about the associations between blood lipids, body mass index (BMI) and dietary cholesterol intakes both within the individual and between related individuals. The purpose of this descriptive research project was to investigate the relationships between LDL and HDL cholesterols, body mass index and dietary cholesterol intakes for a sample of African American (AA) mothers and their daughters and to attempt to separate the contribution of genetic versus environmental factors. Mother and daughter participants (n =42 and 66, respectively) were 12-14-hours fasted when blood samples were drawn, heights and weights measured, and 24 hour food recalls completed.


Qtc Is Associated With Obesity And Physical Activity Level For African American Females, C. Jayne Brahler Apr 2004

Qtc Is Associated With Obesity And Physical Activity Level For African American Females, C. Jayne Brahler

Health and Sport Science Faculty Publications

Long QT syndrome (LQTS) is an independent risk factor for cardiovascular or ischemic disease mortality. Obesity as a cause for acquired LQTS in otherwise healthy individuals is rapidly gaining the attention of the scientific community. African American people have a higher incidence of obesity compared to Caucasians, yet race-specific information is not available for their prevalence of LQTS. Chronic physical activity can help reduce the incidence of obesity, yet little is known about the effects of chronic physical activity on acquired LQTS. Subjects in this study were a volunteer sample of African American mothers (21-53 yr, n = 44) and …


Microscale Investigation Of Thermo-Fluid Transport In The Transition Fil, Region Of An Evaporating Capillary Meniscus Using A Microgravity Environment, Kenneth D. Kihm, Jeffrey S. Allen, Kevin P. Hallinan, David M. Pratt Jan 2004

Microscale Investigation Of Thermo-Fluid Transport In The Transition Fil, Region Of An Evaporating Capillary Meniscus Using A Microgravity Environment, Kenneth D. Kihm, Jeffrey S. Allen, Kevin P. Hallinan, David M. Pratt

Mechanical and Aerospace Engineering Faculty Publications

In order to enhance the fundamental understanding of thin film evaporation and thereby improve the critical design concept for two-phase heat transfer devices, microscale heat and mass transport is to be investigated for the transition film region using state-of-the-art optical diagnostic techniques. By utilizing a microgravity environment, the length scales of the transition film region can be extended sufficiently, from submicron to micron, to probe and measure the microscale transport fields which are affected by intermolecular forces. Extension of the thin film dimensions under microgravity will be achieved by using a conical evaporator made of a thin silicon substrate under …