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Biomechanics Commons

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2023

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Articles 61 - 90 of 107

Full-Text Articles in Biomechanics

The Effect Of Fatigue On Lower Extremity Joint Kinematics And Performance, Shelley Payne, Sarah Alloto, Joe Wilkins, Ashley Simons May 2023

The Effect Of Fatigue On Lower Extremity Joint Kinematics And Performance, Shelley Payne, Sarah Alloto, Joe Wilkins, Ashley Simons

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE

ACL injuries are multifactorial in nature meaning they can be the result of faulty biomechanics, individual genetic predisposition, or environmental factors (Alentorn- Geli et al., 2009). A focus of most healthcare professionals including physical therapists and athletic trainers includes the screening for preventable risk factors for non- contact ACL injuries. Preventable risk factors include asymmetry between a person’s limbs, decreased hamstring strength, increased muscle fatigue, decreased landing angle of hip and knee Tlexion, increased valgus landing, and lack of Tlexibility in the hip internal rotators (Brophy, 2021). Given the short and long-term negative consequences of an ACL injury, it …


The Effects Of Attentional Focus Instructions On Approach Jump Performance, Hanwen Liu May 2023

The Effects Of Attentional Focus Instructions On Approach Jump Performance, Hanwen Liu

Masters Theses & Specialist Projects

Introduction: Attentional focus is a crucial factor that impacts motor learning and performance. Instructions that direct performers’ attention externally (i.e., toward the effects of movements) have been shown to enhance performance compared to those that direct attention internally (i.e., toward the body’s movements). Research has also demonstrated that novices perform better when they are instructed to focus externally on the process of skill execution versus the outcome. However, this effect has not been tested in complex jumping skills that are important in many sports.

Purpose: The aim of this study was to test the effects of internally and externally directed …


Gaze During Turning In Older Adults, Kalina Mavrov May 2023

Gaze During Turning In Older Adults, Kalina Mavrov

Theses/Capstones/Creative Projects

To navigate complex environments, our gaze needs to attenuate to locomotor tasks, such as walking and turning. Shifting gaze (i.e., rotation of the eyes and head), is important when moving through different environments. The aim of this study was to compare gaze anticipation during clinical tests and complex real-world locomotion. I hypothesized that older adults would shift their gaze in a new heading direction in anticipation of turns. I further predicted increased gaze anticipation in tasks that have a high demand for spatial orientation. Participants were asked to complete clinical tasks consisting of a 2-minute walk, figure-8, and 360-turning in …


Effects Of Pubertal Growth Variation On Knee Mechanics During Walking In Female And Male Adolescents, Andrew W. Froehle, Brian A. Edwards, Matthew Peterson, Brian Meyerson, Dana Duren May 2023

Effects Of Pubertal Growth Variation On Knee Mechanics During Walking In Female And Male Adolescents, Andrew W. Froehle, Brian A. Edwards, Matthew Peterson, Brian Meyerson, Dana Duren

School of Health and Exercise Sciences Faculty Publications

Introduction: Puberty substantially alters the body's mechanical properties, neuromuscular control, and sex differences therein, likely contributing to increased, sex-biased knee injury risk during adolescence. Female adolescents have higher risk for knee injuries than male adolescents of similar age engaging in similar physical activities, and much research has investigated sex differences in mechanical risk factors. However, few studies address the considerable variation in pubertal growth (timing, pace), knee mechanics, and injury susceptibility within sexes, or the impact of such growth variation on mechanical injury risk.

Objectives: The present study tested for effects of variation in pubertal growth on established mechanical …


Comparing Lower-Limb Muscle Activity During Gait Performed In Water Versus On Land, Christopher Long May 2023

Comparing Lower-Limb Muscle Activity During Gait Performed In Water Versus On Land, Christopher Long

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

The purpose of this study was to compare lower-limb muscle activation during gait, performed in water versus on land, in order to provide preliminary evidence for the benefit of aquatic treadmill walking in treating individuals with foot drop. Foot drop is a debilitating symptom of several neurological disorders characterized by the inability to dorsiflex the foot while walking. Generally, it is due to weakness in the ankle dorsiflexor muscles and/or increased tone in the plantar flexor muscles. Previous research has found that exercise interventions that demand greater than normal activation of the tibialis anterior (TA) (i.e., the primary ankle dorsiflexor) …


Obstacle Crossing In Healthy Young And Older Individuals, Hope M. Hanson, Ashlyn M. Jendro, Abigail C. Schmitt May 2023

Obstacle Crossing In Healthy Young And Older Individuals, Hope M. Hanson, Ashlyn M. Jendro, Abigail C. Schmitt

Health, Human Performance and Recreation Undergraduate Honors Theses

Introduction: In the United States, the average population age is rising and will continue to increase in the coming years.With an older population comes increased risk of injury associated with falls. Falls are considered a leading cause of injury and death in older individuals, and many falls are caused by body imbalance or obstacle collision due to a clearly visible stationary object (e.g., rug, chair, branch). Older adults tend to cross obstacles with increased toe clearance in order to prevent tripping, but much of what is known about obstacle crossing in older adults is limited to artificial obstacles that are …


Validity Of The Loadsol Pro Insole For Pedal Reaction Force Measurements During Stationary Cycling, Anabelle Vallecillo Bustos May 2023

Validity Of The Loadsol Pro Insole For Pedal Reaction Force Measurements During Stationary Cycling, Anabelle Vallecillo Bustos

Honors Theses

Advancements in wearable technology have allowed clinicians, coaches, and researchers the ability to observe and quantify human movement outside the laboratory. Instrumented insoles are an example of novel technology that can be worn in the shoes and measure vertical reaction force wirelessly. The use of such insoles will prove to be beneficial for athletes as they train, patients as they progress through rehabilitation, and researchers as they experiment in their respective fields. The Loadsol Pro (Novel Inc., St Paul., MN, USA) has been shown to produce accurate and reliable measures of ground reaction forces (GRF) in various dynamic activities including …


Transcutaneous Electrical Stimulation Does Not Decrease Torque Loss Over High Intensity Repetitions, Ian Koskinen May 2023

Transcutaneous Electrical Stimulation Does Not Decrease Torque Loss Over High Intensity Repetitions, Ian Koskinen

All NMU Master's Theses

Transcutaneous Electrical Stimulation, TENS, has been used widely as an analgesic and ergogenic aid for many years. Compared to other modalities of electrical stimulation, TENS has been shown to provide some benefits in exercise performance by reducing pain and increasing endurance in low intensity applications, such as time trial cycling or isometric endurance. While TENS has been shown to have a significant effect on exercise induced pain in individuals performing endurance activities, to my knowledge it has not been examined in high intensity contractions. 18 active young adults (age: 23.11 years ± 2.08, resistance training experience: 7.08 years ± 3.79, …


Opensim-Based Musculoskeletal Modeling: Foundation For Interactive Obstetric Simulator, Bahador Dodge May 2023

Opensim-Based Musculoskeletal Modeling: Foundation For Interactive Obstetric Simulator, Bahador Dodge

Electrical & Computer Engineering Theses & Dissertations

The use of mathematical and computational models to understand complex biological systems, such as the human birth process, is a rapidly growing field in medicine. These models can be used to optimize and personalize medical treatments for individual patients, enhance training, and aid in educational efforts. While recent advancements in healthcare, particularly in obstetrics, have improved care for mothers and babies, studies and government reports indicate a rising rate of maternal mortality in the United States.

Despite this rising trend, there is a lack of detailed studies concerning the use of modeling and simulation to develop an interactive obstetrics simulator …


The Effect Of Running On The Onset And Development Of Osteoarthritis, Jordan Hekman May 2023

The Effect Of Running On The Onset And Development Of Osteoarthritis, Jordan Hekman

Senior Honors Theses

Osteoarthritis is a prominent and debilitating form of joint disease characterized by pain and deterioration of the articular cartilage and other tissues in the affected joint. Research has identified a variety of risk factors for osteoarthritis, including age, obesity, gender, previous injury, and occupation. The relationship between running and osteoarthritis is a topic of particular interest because of the prevalence of running as a simple and physiologically beneficial form of exercise. Increasing evidence suggests that recreational running has at worst no effect and at best a protective effect on joint and articular cartilage health in contrast to high-intensity professional/elite-level running …


Guidelines For “Topics Brief” Submissions, James W. Navalta, Robert Salatto, Donald L. Hoover, Andrea Stevenson Apr 2023

Guidelines For “Topics Brief” Submissions, James W. Navalta, Robert Salatto, Donald L. Hoover, Andrea Stevenson

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 4: Issue 1, Article 6, 2023. The “Topics Brief”, a novel submissions format, is introduced with authors guidelines. Within this submissions format, a category describing a target audience should be identified, such as Topics Brief for: Patients, Clinicians, Practitioners, or Students. Authors may also suggest their own category for a target audience. The title should be descriptive and allow for maximum searchability. Authorship criteria include a substantial contribution, assisting with the manuscript draft, and approval of the final version. The format is open, with a focus of presenting work in a clear and …


Introducing The “Topics Brief”: Bridging The Gap Between University And Non-Academics In A Potentially More Meaningful Way, James W. Navalta, Robert Salatto, Donald L. Hoover, Andrea Stevenson Apr 2023

Introducing The “Topics Brief”: Bridging The Gap Between University And Non-Academics In A Potentially More Meaningful Way, James W. Navalta, Robert Salatto, Donald L. Hoover, Andrea Stevenson

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 4: Issue 1, Article 5, 2023. Introducing the “Topics Brief”, aiming to bridge the gap between university and non-academics. Topics Briefs should include the following: 1. Share what was done to a non-academic audience, 2. Condensed format (limited to 1-2 pages, 1 page preferred), 3. Include only the most important parts (i.e., main concepts, main results, main learned experience) to be implemented in practical application, 4. May be heavily visual (we encourage authors to be creative)


Attentional Focus Effects On Motor Variability, Charlend Kenneth Howard Apr 2023

Attentional Focus Effects On Motor Variability, Charlend Kenneth Howard

LSU Doctoral Dissertations

Subtle changes in task instructions with associated changes of one’s focus of attention (FOA) can have measurable effects on performance and learning of complex motor skills (Wulf, 2013). The beneficial effects of adopting an external focus of attention (EF) have been well-documented in physical environments, and recently have also been demonstrated in virtual reality (VR) environments (Cochran, Aiken, Rhea, & Raisbeck, 2021; Yamada, Kuznetsov, Diekfuss, & Raisbeck, 2021). However, these studies primarily focused on performance outcomes (such as error and accuracy), with relatively less emphasis on movement coordination. Given that most human movements are motor abundant (more degrees of freedom …


Evaluating Foot-Drop Interventions For Multiple Sclerosis Using A Multimodal System, Laura Marie Byrnes-Blanco Mar 2023

Evaluating Foot-Drop Interventions For Multiple Sclerosis Using A Multimodal System, Laura Marie Byrnes-Blanco

USF Tampa Graduate Theses and Dissertations

This dissertation explores how multimodal walking impacts quantitative and qualitative aspects of gait for persons with multiple sclerosis (pwMS) experiencing foot-drop. Foot-drop can dramatically impede mobility and clinicians routinely prescribe ankle-foot-orthosis (AFO) and functional electrical stimulation (FES) devices to alleviate its impacts on daily life. However, little is known about how these devices affect pwMS while traversing environments with real-world complexity. To explore this topic, an interventional, parallel assigned study was conducted. A realistic nature pathway containing changes in floor pitch, audiovisual stimulation, and during-trial tasks (for dual-tasking) was generated in an immersive virtual reality system called CAREN: Computer Assisted …


How Some Arboreal Salamanders (Genus Aneides) Jump, Glide, And Generate Lift, Christian E. Brown Mar 2023

How Some Arboreal Salamanders (Genus Aneides) Jump, Glide, And Generate Lift, Christian E. Brown

USF Tampa Graduate Theses and Dissertations

The jumping and subsequent aerial behaviors of arboreal lungless salamanders (genus Aneides) had never been investigated or described. The aims of this research were to (1) compare jumping performance within the family Plethodontidae with a special focus on arboreal species from genus Aneides, (2) describe the biomechanics and kinematics of aerial behaviors after a jump or extended fall, and (3) model airflow over the morphology of the most aerially adept salamanders to investigate if they are capable of generating lift. First, I recorded salamanders jumping, locomoting vertically, dropping, and flying in a vertical wind tunnel. Then, I laser-scanned and reconstructed …


Accelerometry-Based Analysis Of Postural Sway In Parkinson's Disease Patients With Levodopa-Induced Dyskinesia, Chandler Brock Mar 2023

Accelerometry-Based Analysis Of Postural Sway In Parkinson's Disease Patients With Levodopa-Induced Dyskinesia, Chandler Brock

UNO Student Research and Creative Activity Fair

Parkinson’s disease (PD) is a progressive neurodegenerative disorder, with patient numbers projected to double to 12 million in the next 20 years. Levodopa-induced dyskinesia (LID) is a major problem associated with the long-term use of levodopa for symptomatic treatment of PD. These involuntary movements can become disabling and may interfere with quality of life. Our prior research showed that PD w/ LID were less stable while standing (i.e., increased postural sway) and had a higher incidence of falls. The aim of this study is to determine if postural sway properties are altered by LID via decomposing the sway signal. We …


Walking Easier By Attaching A Spring-Mass To The Body: A Preliminary Simulation, Hiva Razavi, Philippe Malcolm Mar 2023

Walking Easier By Attaching A Spring-Mass To The Body: A Preliminary Simulation, Hiva Razavi, Philippe Malcolm

UNO Student Research and Creative Activity Fair

When carrying or pushing a load, more force is needed to accelerate and decelerate the additional mass, increasing Ground Reaction Force (GRF). However, this can be reduced by synchronizing the object's movement with the individual's Center of Mass (COM) using antiphase acceleration and deceleration. Past studies have shown this can decrease muscle work and metabolic costs. This study aimed to determine optimal spring parameters to minimize horizontal GRF (GRFh) when pushing a cart by connecting the human to the cart with a spring and damper system.

Three walking conditions were simulated in MATLAB: 1) Normal walking; 2) Walking with a …


Attenuated Skeletal Muscle Metabolism Explains Blunted Reactive Hyperemia After Prolonged Sitting, Cody Anderson, Elizabeth Pekas, Michael Allen, Song-Young Park Mar 2023

Attenuated Skeletal Muscle Metabolism Explains Blunted Reactive Hyperemia After Prolonged Sitting, Cody Anderson, Elizabeth Pekas, Michael Allen, Song-Young Park

UNO Student Research and Creative Activity Fair

Introduction: Although reduced post-occlusive reactive hyperemia (PORH) after prolonged sitting (PS) has been reported as impaired microvascular function, no specific mechanism(s) have been elucidated. One potential mechanism, independent of microvascular function, is that an altered muscle metabolic rate (MMR) may change the magnitude of PORH by modifying the oxygen deficit achieved during cuff-induced arterial occlusions. We speculated that if MMR changes during PS, this may invalidate current inferences about microvascular function during PS. Objective: Therefore, the objective of this study was to examine if peripheral leg MMR changes during PS and to ascertain whether the change in the oxygen deficit …


The Effect Of Exoskeleton Footwear On Joint Angular Motion During Walking In Patients With Peripheral Artery Disease, Zahra Salamifar, Farahnaz Fallahtafti, Iraklis I. Pipinos, Jason M. Johanning, Sara Myers Mar 2023

The Effect Of Exoskeleton Footwear On Joint Angular Motion During Walking In Patients With Peripheral Artery Disease, Zahra Salamifar, Farahnaz Fallahtafti, Iraklis I. Pipinos, Jason M. Johanning, Sara Myers

UNO Student Research and Creative Activity Fair

Gait, Lower Extremity, Peripheral Artery Disease, Joint Angle, Exoskeleton Footwear, Exoskeleton, Assistive Device, Walking.


The Effects Of Demographics And Risk Factors On The Morphological Characteristics Of Human Femoropopliteal Arteries, Sayed Ahmadreza Razian, Majid Jadidi, Alexey Kamenskiy Mar 2023

The Effects Of Demographics And Risk Factors On The Morphological Characteristics Of Human Femoropopliteal Arteries, Sayed Ahmadreza Razian, Majid Jadidi, Alexey Kamenskiy

UNO Student Research and Creative Activity Fair

Background: Disease of the lower extremity arteries (Peripheral Arterial Disease, PAD) is associated with high morbidity and mortality. During disease development, the arteries adapt by changing their diameter, wall thickness, and residual deformations, but the effects of demographics and risk factors on this process are not clear.

Methods: Superficial femoral arteries from 736 subjects (505 male, 231 female, 12 to 99 years old, average age 51±17.8 years) and the associated demographic and risk factor variables were used to construct machine learning (ML) regression models that predicted morphological characteristics (diameter, wall thickness, and longitudinal opening angle resulting from the …


The Top 50 Most Cited Articles On The Medial Patellofemoral Ligament (Mpfl): A Bibliometric Analysis, Varag Abed, Alex Duvall, Jonathan D. Rexroth, Alyssa Goodwin, Joseph Liu, Austin Stone Mar 2023

The Top 50 Most Cited Articles On The Medial Patellofemoral Ligament (Mpfl): A Bibliometric Analysis, Varag Abed, Alex Duvall, Jonathan D. Rexroth, Alyssa Goodwin, Joseph Liu, Austin Stone

Medical Student Research Symposium

Objectives: To determine which original articles on the topic of the medial patellofemoral ligament (MPFL) have been cited the most in the literature utilizing a bibliometric approach. Secondarily, to determine temporal trends between article types.

Methods: Articles on the topic of the MPFL were identified by utilizing the Web of Science Database. The search yielded 1,596 results and the top 50 cited original articles were collected for further analysis. The following information was gathered for all included articles: title, first author's name, journal name, year of publication, impact factor of the journal in 2021, total number of citations of the …


Human Spacesuit Interaction During Eva Of The Legs Using A Force Sensing System, Niraliben D. Patel Mar 2023

Human Spacesuit Interaction During Eva Of The Legs Using A Force Sensing System, Niraliben D. Patel

USF Tampa Graduate Theses and Dissertations

Astronauts perform a multitude of tasks in space, both in the spacecraft and outside of the spacecraft. Extravehicular Activity (EVA) refers to any activity that is completed outside of the spacecraft, whether it is work on the actual spacecraft, spacewalks, or conducting sample collections on other planets and moons. To do this safely, a pressurized Extravehicular Mobility Unit (EMU) or commonly known as the spacesuit is used. There have been multiple iterations of the United States EMU with advances to further optimize the astronaut safety and EVA tasks. However, there is still relatively little information on the movement of the …


Muscular Strength Predicts Phase Angle In Breast Cancer Survivors, Trevor Short, Cheri Teranishi-Hashimoto, Paulette Yamada Mar 2023

Muscular Strength Predicts Phase Angle In Breast Cancer Survivors, Trevor Short, Cheri Teranishi-Hashimoto, Paulette Yamada

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 4: Issue 1, Article 4, 2023. Phase angle (PhA) has emerged as a prognostic indicator of survival and quality of life (QOL) in cancer patients. Identifying measures of physical fitness that correlate with PhA can provide guidance toward optimizing cancer rehabilitation programs and future research. The purpose was to examine the relationship between PhA and physical fitness in breast cancer survivors. Sixty-three breast cancer survivors (60 ± 9 years, PhA 4.59±0.52, mean±SD) completed assessments for muscular strength, muscular endurance, cardiorespiratory endurance, flexibility, and body composition. PhA and body composition were measured using bioimpedance …


The Pursuit Of Peak Athletic Performance, Trevor Short Mar 2023

The Pursuit Of Peak Athletic Performance, Trevor Short

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 4: Issue 1, Article 3, 2023. Achieving peak performance in sports is a multifactorial phenomenon that spans several scientific disciplines. The optimization of human performance requires a comprehensive and systematic assessment that identifies potential performance-inhibiting factors. The result of such analysis allows for more individualized and accurate evaluation, athlete monitoring, and training interventions. Thus, there is a need for a multidisciplinary model of peak performance to guide practitioners when conducting a comprehensive analysis. The purpose of this manuscript is to provide a brief but practical vade mecum for practitioners to consider in the …


Changes In Attitudes And Functional Performance After An Educational Intervention And Participation In The Dime In Cadets, Emily Gabriel, Cameron Powden Feb 2023

Changes In Attitudes And Functional Performance After An Educational Intervention And Participation In The Dime In Cadets, Emily Gabriel, Cameron Powden

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Introduction: Cadets frequently suffer from lower extremity injuries, but fail to participate in effective injury prevention programs (IPPs). The purpose of this study was to determine if an intervention focused on benefits and barriers of IPP with participation in an IPP would change attitudes towards participating in IPPs and functional performance. Methods: Thirty-four ROTC cadets (Male: n=28, Age: 19.67±1.45 years, Height: 175.57±8.30cm, Mass: 75.38±14.30kg) volunteered to participate in the study. Participants completed the Health Belief Model Scale (HBMS), Theory of Planned Behavior Scale (TPBS), Y-Balance test, Landing Error Scoring System, 2-mile run, push-up test, and sit-up test. During the Army …


The Theory Of Planned Behavior As A Framework To Identify Attitudes And Perceptions Of Athletic Trainers Towards Quality Improvement, Meredith Madden, Dominique M. Ross Feb 2023

The Theory Of Planned Behavior As A Framework To Identify Attitudes And Perceptions Of Athletic Trainers Towards Quality Improvement, Meredith Madden, Dominique M. Ross

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: The BOC announced a concept for continuing professional certification for athletic trainers (ATs), including an optional quality improvement (QI) project to examine practice performance. The purpose of this study was to examine current attitudes, perceived control and subjective norms of ATs regarding QI. Method: Data was collected using a qualitative descriptive design. A web-based survey was distributed via email and social media. Open-ended questions were evaluated by two independent coders using a general inductive approach. Results: Three major themes emerged: reservations about QI, benefits of QI, and impacts on the profession. Conclusions: When integrated into the Theory of Planned …


Multiple Behaviors For Turning Performance Of Pacific Bluefin Tuna (Thunnus Orientalis), Abigail M. Downs, Allison Kolpas, Barbara A. Block, Frank E. Fish Feb 2023

Multiple Behaviors For Turning Performance Of Pacific Bluefin Tuna (Thunnus Orientalis), Abigail M. Downs, Allison Kolpas, Barbara A. Block, Frank E. Fish

Biology Faculty Publications

Tuna are known for exceptional swimming speeds, which are possible because of their thunniform lift-based propulsion, large muscle mass and rigid fusiform body. A rigid body should restrict maneuverability with regard to turn radius and turn rate. To test if turning maneuvers by the Pacific bluefin tuna (Thunnus orientalis) are constrained by rigidity, captive animals were videorecorded overhead as the animals routinely swam around a large circular tank or during feeding bouts. Turning performance was classified into three different types: (1) glide turns, where the tuna uses the caudal fin as a rudder; (2) powered turns, where the animal uses …


A Molecular Signature Defining Exercise Adaptation With Ageing And In Vivo Partial Reprogramming In Skeletal Muscle, Ronald G. Jones Iii, Andrea Dimet-Wiley, Amin Haghani, Francielly Morena Da Silva, Camille R. Brightwell, Seongkyun Lim, Sabin Khadgi, Yuan Wen, Corey M. Dungan, Robert T. Brooke, Nicholas P. Greene, Charlotte A. Peterson, John J. Mccarthy, Steve Horvath, Stanley J. Watowich, Christopher S. Fry, Kevin A. Murach Feb 2023

A Molecular Signature Defining Exercise Adaptation With Ageing And In Vivo Partial Reprogramming In Skeletal Muscle, Ronald G. Jones Iii, Andrea Dimet-Wiley, Amin Haghani, Francielly Morena Da Silva, Camille R. Brightwell, Seongkyun Lim, Sabin Khadgi, Yuan Wen, Corey M. Dungan, Robert T. Brooke, Nicholas P. Greene, Charlotte A. Peterson, John J. Mccarthy, Steve Horvath, Stanley J. Watowich, Christopher S. Fry, Kevin A. Murach

Health, Human Performance and Recreation Faculty Publications and Presentations

Exercise promotes functional improvements in aged tissues, but the extent to which it simulates partial molecular reprogramming is unknown. Using transcriptome profiling from (1) a skeletal muscle-specific in vivo Oct3/4, Klf4, Sox2 and Myc (OKSM) reprogramming-factor expression murine model; (2) an in vivo inducible muscle-specific Myc induction murine model; (3) a translatable high-volume hypertrophic exercise training approach in aged mice; and (4) human exercise muscle biopsies, we collectively defined exercise-induced genes that are common to partial reprogramming. Late-life exercise training lowered murine DNA methylation age according to several contemporary muscle-specific clocks. A comparison of the murine soleus transcriptome …


Effects Of A Race Timer On The 3-Minute All-Out Test For Critical Power, Paul Mandell, Boe Burrus, Taylor Bloedon Jan 2023

Effects Of A Race Timer On The 3-Minute All-Out Test For Critical Power, Paul Mandell, Boe Burrus, Taylor Bloedon

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 4: Issue 1, Article 2, 2023. The 3-min all-out cycling test (3MT) elicits valuable fitness metrics including V̇O2peak, HRmax, Critical Power (CP), and Work Above End Power (WEP; equivalent to work prime; W’). Twelve (n = 12) healthy active males were recruited to participate in the current study on the effects of the implementation of a race timer on the 3MT. Participants completed a V̇O2peak test and one 3MT familiarization trial before completing one standard 3MT and one 3MT with the presence of a countdown race timer in …


Biomechanically-Consistent Skin Stretch As An Intuitive Mechanism For Sensory Feedback: A Preliminary Investigation In The Lower Limb, Jenny A. Kent Jan 2023

Biomechanically-Consistent Skin Stretch As An Intuitive Mechanism For Sensory Feedback: A Preliminary Investigation In The Lower Limb, Jenny A. Kent

Physical Therapy Faculty Research

The proprioceptive loss accompanied by lower limb amputation can impair function and mobility. We explore a simple, mechanical skin-stretch array configured to generate superficial tissue behaviour that might occur with movement about an intact joint. Four adhesive pads attached around the circumference of the lower leg were connected via cords to a remote “foot” mounted on a ball joint attached to the underside of a fracture boot, such that “foot” reorientation would result in skin stretch. In two discrimination experiments performed with and without the connection, with no view of the mechanism, and with minimal training, unimpaired adults (i) estimated …