Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Institution
- Publication
- Publication Type
Articles 1 - 5 of 5
Full-Text Articles in Kinesiology
Acute Exercise And Oxidative Stress: Crossfit™ Vs. Treadmill Bout, Brian Kliszczewicz, Quindry C. John, Blessing L. Daniel, Oliver D. Gretchen
Acute Exercise And Oxidative Stress: Crossfit™ Vs. Treadmill Bout, Brian Kliszczewicz, Quindry C. John, Blessing L. Daniel, Oliver D. Gretchen
Faculty and Research Publications
CrossFit™, a popular high-intensity training modality, has been the subject of scrutiny, with concerns of elevated risk of injury and health. Despite these concerns empirical evidence regarding physiologic stresses including acute oxidative stress is lacking. Therefore, the purpose of this investigation was to examine the acute redox response to a CrossFit™ bout. Furthermore, these findings were compared to a high-intensity treadmill bout as a point of reference. Ten males 26.4 ± 2.7 yrs having three or more months of CrossFit™ experience participated in the present study. Blood plasma was collected at four time points: Pre-exercise (PRE), immediately-post-exercise (IPE), 1 hr-post …
High-Density Lipoprotein Antioxidant Responses To High-Intensity Interval And Steady-State Moderate-Intensity Exercise, Zacharias Papadakis, Jeffrey S. Forsse, Annie A. Bane, Taylor Kyle, Li Qian, Flor Elisa Morales Marroquín, Peter W. Grandjean
High-Density Lipoprotein Antioxidant Responses To High-Intensity Interval And Steady-State Moderate-Intensity Exercise, Zacharias Papadakis, Jeffrey S. Forsse, Annie A. Bane, Taylor Kyle, Li Qian, Flor Elisa Morales Marroquín, Peter W. Grandjean
International Journal of Exercise Science: Conference Proceedings
High-intensity interval exercise (HIIE) may impart health benefits beyond what is acquired through moderate-intensity steady state exercise (SSE). Paraoxonase 1 (PON1), an antioxidant associated with high-density lipoprotein (HDL), may be altered with exercise; however, it is unclear whether HIIE provides a greater stimulus for increasing PON1 antioxidant activity than a comparable or greater amount of SSE. PURPOSE: Determine the influence of HIIE on PON1 concentration and activity relative to a comparable amount of moderate-intensity SSE and a dose that is half that of SSE. METHODS: Seventeen male participants (age 27.8 + 6.4 yr; weight 80.6 + 9.0 kg; BMI 25.1 …
Supra-Physiological Doses Of Testosterone Affect Membrane Oxidation Of Human Neutrophils Monitored By The Fluorescent Probe C11-Bodipy581/591, Tacito Pessoa De Souza Jr, Andre K. Yamada, Roberto Simao, Tatiana G. Polotow, Rui Curi, Zachary Pope, Jeffrey Willardson, Marcelo P. Barros
Supra-Physiological Doses Of Testosterone Affect Membrane Oxidation Of Human Neutrophils Monitored By The Fluorescent Probe C11-Bodipy581/591, Tacito Pessoa De Souza Jr, Andre K. Yamada, Roberto Simao, Tatiana G. Polotow, Rui Curi, Zachary Pope, Jeffrey Willardson, Marcelo P. Barros
Faculty Research and Creative Activity
The purpose of this study was to determine the effects of supra-physiological doses of testosterone (TES) on membrane oxidation of activated human neutrophils in vitro using an innovative and sensitive technique: the real-time detection with the fluorescence probe C11-BODIPY581/591. Methodological controls were performed with the lipid-soluble and powerful antioxidant astaxanthin at different neutrophil density cultures. Neutrophils from nine healthy young men (23.4 ± 2.5 years, 174.4 ± 7.0 cm height, and 78.3 ± 7.0 kg weight) were isolated and treated with 0.1 or 10 μM TES for 24 h and subsequently labeled with the free radical-sensitive probe C11-BODIPY581/591 for monitoring …
Supra-Physiological Doses Of Testosterone Affect Membrane Oxidation Of Human Neutrophils Monitored By The Fluorescent Probe C11-Bodipy581/591, Tacito Pessoa De Souza Jr, Andre K. Yamada, Roberto Simao, Tatiana G. Polotow, Rui Curi, Zachary Pope, Jeffrey Willardson, Marcelo P. Barros
Supra-Physiological Doses Of Testosterone Affect Membrane Oxidation Of Human Neutrophils Monitored By The Fluorescent Probe C11-Bodipy581/591, Tacito Pessoa De Souza Jr, Andre K. Yamada, Roberto Simao, Tatiana G. Polotow, Rui Curi, Zachary Pope, Jeffrey Willardson, Marcelo P. Barros
Jeffrey Willardson
The purpose of this study was to determine the effects of supra-physiological doses of testosterone (TES) on membrane oxidation of activated human neutrophils in vitro using an innovative and sensitive technique: the real-time detection with the fluorescence probe C11-BODIPY581/591. Methodological controls were performed with the lipid-soluble and powerful antioxidant astaxanthin at different neutrophil density cultures. Neutrophils from nine healthy young men (23.4 ± 2.5 years, 174.4 ± 7.0 cm height, and 78.3 ± 7.0 kg weight) were isolated and treated with 0.1 or 10 μM TES for 24 h and subsequently labeled with the free radical-sensitive probe C11-BODIPY581/591 for monitoring …
Relationship Between Circulating Progenitor Cells, Vascular Function And Oxidative Stress With Long-Term Training And Short-Term Detraining In Older Men, Sarah Witkowski, Michael M. Lockard, Nathan T. Jenkins, Thomas O. Obisesan, Espen E. Spangenburg, James M. Hagberg
Relationship Between Circulating Progenitor Cells, Vascular Function And Oxidative Stress With Long-Term Training And Short-Term Detraining In Older Men, Sarah Witkowski, Michael M. Lockard, Nathan T. Jenkins, Thomas O. Obisesan, Espen E. Spangenburg, James M. Hagberg
Exercise and Sport Studies: Faculty Publications
Exercise may contribute to the maintenance of vascular function via enhanced liberation and action of bone-marrow-derived progenitor cells. Activity related changes in oxidative stress may also influence the number and function of these cells. In the present study, we sought to determine (i) whether adaptations in reactive hyperaemic FBF (forearm blood flow) response associated with long-term endurance exercise and short-term detraining were related to resting putative progenitor cell number and function, and (ii) whether oxidative stress affected these factors. Participants included men with a history of more than 30 years of moderate-to-high-intensity exercise (HI group) and healthy low-active age- and …